Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01403:Vmn2r103'

79693

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r103

Ensembl Gene

ENSMUSG00000091771

Gene Name

vomeronasal 2, receptor 103

Synonyms

EG627636

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.058) question?

Stock #

IGL01403

Quality Score

Status

Chromosome

Chromosomal Location

19993625-20032798 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 20013229 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 117 (Y117H)

Ref Sequence

ENSEMBL: ENSMUSP00000126756 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000172203]

AlphaFold

E9PWW0

Predicted Effect

probably benign
Transcript: ENSMUST00000172203
AA Change: Y117H

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000126756
Gene: ENSMUSG00000091771
AA Change: Y117H

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	82	449	1.3e-37	PFAM
Pfam:NCD3G	509	562	3.5e-22	PFAM
Pfam:7tm_3	595	830	1.1e-51	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb5	A	T	12: 118,836,602 (GRCm39)	L1103Q	probably damaging	Het
Adam12	T	A	7: 133,521,339 (GRCm39)	Q605L	probably benign	Het
Adk	A	G	14: 21,284,983 (GRCm39)	K102R	probably damaging	Het
Afdn	C	T	17: 14,124,132 (GRCm39)	P1761S	probably damaging	Het
Ascc1	A	G	10: 59,848,280 (GRCm39)		probably benign	Het
Aspdh	A	G	7: 44,115,983 (GRCm39)		probably null	Het
Bbx	T	C	16: 50,022,876 (GRCm39)	I753V	probably benign	Het
Ccdc33	T	C	9: 58,024,668 (GRCm39)	Y186C	probably damaging	Het
Ccdc78	T	A	17: 26,007,218 (GRCm39)		probably null	Het
Ckmt1	T	C	2: 121,193,447 (GRCm39)		probably benign	Het
Csf1r	A	G	18: 61,247,897 (GRCm39)	T322A	probably benign	Het
Dnah7b	T	C	1: 46,155,460 (GRCm39)		probably benign	Het
Dr1	A	G	5: 108,417,576 (GRCm39)	N41D	possibly damaging	Het
Ehmt1	G	A	2: 24,729,638 (GRCm39)	T633I	possibly damaging	Het
Fgf7	T	A	2: 125,877,860 (GRCm39)	Y76N	probably damaging	Het
Hmcn1	A	T	1: 150,468,848 (GRCm39)	W5038R	probably damaging	Het
Ighv14-1	A	G	12: 113,895,862 (GRCm39)	V21A	probably damaging	Het
Igkv5-37	T	A	6: 69,940,420 (GRCm39)	I75F	probably damaging	Het
Inhbc	T	A	10: 127,205,968 (GRCm39)	I100F	probably damaging	Het
Irs3	A	G	5: 137,643,581 (GRCm39)	F68L	probably damaging	Het
Itpr3	T	A	17: 27,337,569 (GRCm39)	C2460S	probably damaging	Het
Krt34	A	G	11: 99,929,116 (GRCm39)	C365R	possibly damaging	Het
Krt81	G	A	15: 101,361,269 (GRCm39)	H104Y	probably benign	Het
Ly6g	A	G	15: 75,030,497 (GRCm39)	N82S	probably damaging	Het
Mrpl58	A	T	11: 115,297,404 (GRCm39)	I72F	probably damaging	Het
Myo9a	G	A	9: 59,778,846 (GRCm39)	R1534H	probably damaging	Het
Npat	T	A	9: 53,466,429 (GRCm39)	F239L	probably benign	Het
Nsd2	A	G	5: 34,042,722 (GRCm39)		probably benign	Het
Nuggc	T	C	14: 65,860,635 (GRCm39)	V427A	probably benign	Het
Or52b1	G	A	7: 104,978,605 (GRCm39)	R265C	probably benign	Het
Or5p55	A	G	7: 107,566,828 (GRCm39)	T75A	possibly damaging	Het
Pde4a	A	T	9: 21,116,412 (GRCm39)	I467F	probably damaging	Het
Pkhd1l1	T	A	15: 44,347,229 (GRCm39)	C198*	probably null	Het
Pla2r1	A	G	2: 60,254,632 (GRCm39)	V1312A	probably damaging	Het
Pola2	T	C	19: 6,009,121 (GRCm39)	H79R	probably benign	Het
Potefam1	T	C	2: 111,059,515 (GRCm39)		probably benign	Het
Pramel15	A	T	4: 144,103,703 (GRCm39)	M141K	probably benign	Het
Psen2	A	T	1: 180,062,548 (GRCm39)		probably benign	Het
Rnf213	A	G	11: 119,334,126 (GRCm39)	K3112E	probably damaging	Het
Slc6a4	G	T	11: 76,922,498 (GRCm39)	V630L	probably benign	Het
Smg1	A	T	7: 117,757,355 (GRCm39)		probably benign	Het
Tmc8	A	G	11: 117,681,900 (GRCm39)	T510A	possibly damaging	Het
Usp18	T	A	6: 121,245,627 (GRCm39)	H334Q	possibly damaging	Het
Vps13b	T	A	15: 35,709,625 (GRCm39)	D1857E	probably benign	Het

Other mutations in Vmn2r103

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00333:Vmn2r103	APN	17	20,013,364 (GRCm39)	missense	probably damaging	0.98
IGL00939:Vmn2r103	APN	17	20,015,227 (GRCm39)	missense	probably benign	0.00
IGL01120:Vmn2r103	APN	17	20,013,259 (GRCm39)	missense	probably benign	0.06
IGL01404:Vmn2r103	APN	17	20,032,696 (GRCm39)	missense	probably damaging	1.00
IGL01713:Vmn2r103	APN	17	20,014,330 (GRCm39)	missense	probably damaging	1.00
IGL01802:Vmn2r103	APN	17	20,019,470 (GRCm39)	missense	probably benign
IGL02251:Vmn2r103	APN	17	20,014,231 (GRCm39)	missense	possibly damaging	0.84
IGL02466:Vmn2r103	APN	17	19,993,631 (GRCm39)	missense	probably benign
IGL02555:Vmn2r103	APN	17	20,031,873 (GRCm39)	missense	probably damaging	1.00
IGL02668:Vmn2r103	APN	17	20,014,389 (GRCm39)	missense	probably benign	0.03
IGL02715:Vmn2r103	APN	17	20,014,218 (GRCm39)	missense	probably damaging	0.97
IGL02735:Vmn2r103	APN	17	20,032,510 (GRCm39)	missense	probably benign	0.27
IGL03101:Vmn2r103	APN	17	19,993,782 (GRCm39)	missense	probably damaging	0.98
R0003:Vmn2r103	UTSW	17	20,032,241 (GRCm39)	missense	probably damaging	0.99
R0052:Vmn2r103	UTSW	17	20,031,903 (GRCm39)	missense	probably benign	0.01
R0375:Vmn2r103	UTSW	17	20,013,726 (GRCm39)	missense	probably benign	0.12
R0375:Vmn2r103	UTSW	17	20,013,121 (GRCm39)	missense	probably benign	0.06
R0755:Vmn2r103	UTSW	17	19,993,830 (GRCm39)	missense	probably benign	0.01
R0837:Vmn2r103	UTSW	17	20,014,189 (GRCm39)	missense	probably damaging	0.99
R1345:Vmn2r103	UTSW	17	20,014,509 (GRCm39)	missense	probably damaging	1.00
R1396:Vmn2r103	UTSW	17	20,013,230 (GRCm39)	missense	probably benign
R1488:Vmn2r103	UTSW	17	20,013,922 (GRCm39)	missense	probably damaging	0.97
R1533:Vmn2r103	UTSW	17	19,993,662 (GRCm39)	missense	probably benign	0.01
R1590:Vmn2r103	UTSW	17	20,014,496 (GRCm39)	missense	probably benign
R1928:Vmn2r103	UTSW	17	20,032,029 (GRCm39)	missense	possibly damaging	0.95
R1942:Vmn2r103	UTSW	17	20,032,562 (GRCm39)	missense	probably benign	0.02
R2071:Vmn2r103	UTSW	17	20,014,056 (GRCm39)	missense	probably benign
R2219:Vmn2r103	UTSW	17	20,013,909 (GRCm39)	missense	probably damaging	1.00
R2442:Vmn2r103	UTSW	17	19,993,793 (GRCm39)	missense	probably benign	0.00
R2889:Vmn2r103	UTSW	17	20,013,862 (GRCm39)	missense	probably damaging	1.00
R3762:Vmn2r103	UTSW	17	20,032,411 (GRCm39)	missense	probably damaging	0.98
R4014:Vmn2r103	UTSW	17	20,013,866 (GRCm39)	missense	possibly damaging	0.67
R4331:Vmn2r103	UTSW	17	20,014,495 (GRCm39)	missense	probably benign	0.00
R4630:Vmn2r103	UTSW	17	20,013,958 (GRCm39)	missense	probably benign	0.04
R4631:Vmn2r103	UTSW	17	20,013,958 (GRCm39)	missense	probably benign	0.04
R4632:Vmn2r103	UTSW	17	20,013,958 (GRCm39)	missense	probably benign	0.04
R4660:Vmn2r103	UTSW	17	20,032,077 (GRCm39)	missense	probably damaging	1.00
R4801:Vmn2r103	UTSW	17	20,015,338 (GRCm39)	missense	probably benign	0.06
R4802:Vmn2r103	UTSW	17	20,015,338 (GRCm39)	missense	probably benign	0.06
R4931:Vmn2r103	UTSW	17	20,032,031 (GRCm39)	missense	probably benign	0.01
R4995:Vmn2r103	UTSW	17	19,993,773 (GRCm39)	missense	probably benign	0.14
R5309:Vmn2r103	UTSW	17	20,013,296 (GRCm39)	missense	probably benign	0.01
R5312:Vmn2r103	UTSW	17	20,013,296 (GRCm39)	missense	probably benign	0.01
R5329:Vmn2r103	UTSW	17	20,032,433 (GRCm39)	missense	probably damaging	1.00
R5611:Vmn2r103	UTSW	17	20,013,904 (GRCm39)	missense	probably damaging	0.99
R5684:Vmn2r103	UTSW	17	20,013,251 (GRCm39)	missense	probably benign	0.02
R5715:Vmn2r103	UTSW	17	20,015,201 (GRCm39)	missense	probably benign	0.17
R5907:Vmn2r103	UTSW	17	20,032,715 (GRCm39)	missense	possibly damaging	0.67
R6029:Vmn2r103	UTSW	17	20,014,478 (GRCm39)	nonsense	probably null
R6114:Vmn2r103	UTSW	17	20,032,587 (GRCm39)	missense	probably damaging	0.99
R6285:Vmn2r103	UTSW	17	20,032,406 (GRCm39)	missense	probably benign
R6292:Vmn2r103	UTSW	17	20,013,866 (GRCm39)	missense	possibly damaging	0.67
R6334:Vmn2r103	UTSW	17	20,014,344 (GRCm39)	missense	probably damaging	0.97
R6501:Vmn2r103	UTSW	17	20,032,166 (GRCm39)	missense	probably benign	0.29
R6710:Vmn2r103	UTSW	17	20,032,239 (GRCm39)	missense	probably damaging	1.00
R6774:Vmn2r103	UTSW	17	19,993,773 (GRCm39)	missense	probably benign	0.14
R6981:Vmn2r103	UTSW	17	20,013,739 (GRCm39)	missense	probably benign	0.00
R7768:Vmn2r103	UTSW	17	20,032,314 (GRCm39)	missense	probably damaging	0.99
R7816:Vmn2r103	UTSW	17	20,014,476 (GRCm39)	missense	probably benign	0.06
R7885:Vmn2r103	UTSW	17	20,013,385 (GRCm39)	missense	probably benign	0.25
R8002:Vmn2r103	UTSW	17	20,019,511 (GRCm39)	missense	probably damaging	1.00
R8031:Vmn2r103	UTSW	17	20,013,759 (GRCm39)	missense	probably benign	0.00
R8140:Vmn2r103	UTSW	17	20,032,058 (GRCm39)	missense	probably damaging	1.00
R8186:Vmn2r103	UTSW	17	20,032,205 (GRCm39)	missense	probably damaging	1.00
R8559:Vmn2r103	UTSW	17	20,032,646 (GRCm39)	missense	probably benign	0.01
R9413:Vmn2r103	UTSW	17	20,032,158 (GRCm39)	missense	possibly damaging	0.54
R9591:Vmn2r103	UTSW	17	20,031,921 (GRCm39)	missense	possibly damaging	0.70
R9652:Vmn2r103	UTSW	17	20,014,027 (GRCm39)	missense	probably benign	0.01
R9680:Vmn2r103	UTSW	17	20,019,525 (GRCm39)	nonsense	probably null
R9743:Vmn2r103	UTSW	17	20,032,475 (GRCm39)	missense	probably damaging	1.00
Z1088:Vmn2r103	UTSW	17	20,015,309 (GRCm39)	missense	probably benign	0.08

Posted On

2013-11-05