Incidental Mutation 'IGL01404:Vmn2r103'
| ID |
79736 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn2r103
|
| Ensembl Gene |
ENSMUSG00000091771 |
| Gene Name |
vomeronasal 2, receptor 103 |
| Synonyms |
EG627636 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.059)
|
| Stock # |
IGL01404
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
19773363-19812536 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 19812434 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Methionine
at position 823
(I823M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000126756
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000172203]
|
| AlphaFold |
E9PWW0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000172203
AA Change: I823M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126756
Gene: ENSMUSG00000091771
AA Change: I823M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:ANF_receptor
|
82 |
449 |
1.3e-37 |
PFAM |
|
Pfam:NCD3G
|
509 |
562 |
3.5e-22 |
PFAM |
|
Pfam:7tm_3
|
595 |
830 |
1.1e-51 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
T |
A |
12: 71,164,378 (GRCm38) |
|
probably null |
Het |
| 4921524L21Rik |
T |
C |
18: 6,638,653 (GRCm38) |
S351P |
possibly damaging |
Het |
| Ablim3 |
A |
G |
18: 61,871,683 (GRCm38) |
Y12H |
probably damaging |
Het |
| Adam2 |
C |
T |
14: 66,077,210 (GRCm38) |
|
probably null |
Het |
| Adgre4 |
A |
T |
17: 55,797,639 (GRCm38) |
N235I |
possibly damaging |
Het |
| Aldh3b1 |
A |
C |
19: 3,921,205 (GRCm38) |
V153G |
probably benign |
Het |
| B430306N03Rik |
A |
G |
17: 48,321,073 (GRCm38) |
Y177C |
probably damaging |
Het |
| Cast |
A |
T |
13: 74,738,287 (GRCm38) |
Y249* |
probably null |
Het |
| Cfap43 |
T |
C |
19: 47,795,666 (GRCm38) |
D476G |
probably benign |
Het |
| Cpa4 |
T |
C |
6: 30,581,702 (GRCm38) |
I216T |
possibly damaging |
Het |
| Cpeb3 |
T |
C |
19: 37,088,548 (GRCm38) |
D407G |
probably benign |
Het |
| Ctnnal1 |
T |
C |
4: 56,829,590 (GRCm38) |
D413G |
probably damaging |
Het |
| Cyb5a |
A |
G |
18: 84,877,860 (GRCm38) |
S84G |
probably benign |
Het |
| Dpy19l4 |
C |
A |
4: 11,273,006 (GRCm38) |
|
probably null |
Het |
| Erbin |
A |
T |
13: 103,839,464 (GRCm38) |
S641T |
probably damaging |
Het |
| Espn |
T |
A |
4: 152,138,444 (GRCm38) |
T326S |
probably benign |
Het |
| Extl1 |
T |
C |
4: 134,359,203 (GRCm38) |
M514V |
probably benign |
Het |
| Fancc |
G |
A |
13: 63,361,638 (GRCm38) |
L134F |
probably damaging |
Het |
| Fis1 |
C |
T |
5: 136,965,974 (GRCm38) |
A90V |
probably benign |
Het |
| Gdi2 |
A |
G |
13: 3,564,611 (GRCm38) |
T319A |
probably benign |
Het |
| Gjc3 |
A |
G |
5: 137,957,858 (GRCm38) |
F55S |
probably damaging |
Het |
| Gm10762 |
C |
T |
2: 128,967,085 (GRCm38) |
|
probably benign |
Het |
| Got1 |
A |
G |
19: 43,504,609 (GRCm38) |
I291T |
possibly damaging |
Het |
| Gpr179 |
C |
A |
11: 97,338,186 (GRCm38) |
G1048* |
probably null |
Het |
| Ino80 |
T |
A |
2: 119,456,718 (GRCm38) |
D56V |
possibly damaging |
Het |
| Kcp |
C |
A |
6: 29,496,639 (GRCm38) |
C624F |
probably damaging |
Het |
| Kctd1 |
T |
A |
18: 14,969,553 (GRCm38) |
Q857L |
probably damaging |
Het |
| Lins1 |
G |
A |
7: 66,713,928 (GRCm38) |
V524I |
probably damaging |
Het |
| Lrp1 |
A |
T |
10: 127,595,032 (GRCm38) |
Y383N |
probably damaging |
Het |
| Mgam |
A |
C |
6: 40,644,945 (GRCm38) |
K84Q |
probably benign |
Het |
| Mib2 |
T |
A |
4: 155,654,936 (GRCm38) |
E862V |
probably damaging |
Het |
| Myh1 |
G |
T |
11: 67,222,151 (GRCm38) |
R1827L |
possibly damaging |
Het |
| Myh10 |
T |
C |
11: 68,752,040 (GRCm38) |
|
probably null |
Het |
| Myo1e |
A |
G |
9: 70,337,766 (GRCm38) |
Y382C |
probably benign |
Het |
| Nktr |
G |
A |
9: 121,741,152 (GRCm38) |
|
probably null |
Het |
| Nlrc4 |
A |
G |
17: 74,445,711 (GRCm38) |
I559T |
probably damaging |
Het |
| Nod2 |
A |
T |
8: 88,663,736 (GRCm38) |
M224L |
probably benign |
Het |
| Olfr175-ps1 |
G |
A |
16: 58,824,595 (GRCm38) |
T38I |
probably damaging |
Het |
| Olfr658 |
A |
T |
7: 104,644,480 (GRCm38) |
Y295* |
probably null |
Het |
| Olfr984 |
A |
G |
9: 40,101,262 (GRCm38) |
I76T |
probably benign |
Het |
| Pex7 |
G |
T |
10: 19,894,811 (GRCm38) |
|
probably benign |
Het |
| Ptprb |
A |
T |
10: 116,339,436 (GRCm38) |
D1112V |
probably benign |
Het |
| Rubcn |
G |
A |
16: 32,827,296 (GRCm38) |
T636M |
probably damaging |
Het |
| Scn5a |
A |
C |
9: 119,486,470 (GRCm38) |
L1724R |
probably damaging |
Het |
| Sec14l2 |
T |
C |
11: 4,116,710 (GRCm38) |
D34G |
possibly damaging |
Het |
| Serpina3k |
A |
G |
12: 104,340,623 (GRCm38) |
D38G |
probably benign |
Het |
| Sh3bgr |
A |
C |
16: 96,206,490 (GRCm38) |
K18N |
probably damaging |
Het |
| Sh3bp5l |
A |
T |
11: 58,346,060 (GRCm38) |
H281L |
probably benign |
Het |
| Slc28a2 |
T |
G |
2: 122,452,057 (GRCm38) |
I287M |
probably damaging |
Het |
| Slc2a1 |
T |
A |
4: 119,132,238 (GRCm38) |
M45K |
possibly damaging |
Het |
| Syt11 |
A |
G |
3: 88,762,216 (GRCm38) |
I123T |
probably benign |
Het |
| Tfg |
C |
A |
16: 56,694,493 (GRCm38) |
|
probably benign |
Het |
| Tmem177 |
T |
C |
1: 119,910,061 (GRCm38) |
D296G |
probably damaging |
Het |
| Trabd2b |
A |
G |
4: 114,599,956 (GRCm38) |
I357V |
probably benign |
Het |
| Trp63 |
C |
A |
16: 25,820,385 (GRCm38) |
|
probably benign |
Het |
| Ugt1a8 |
T |
C |
1: 88,087,895 (GRCm38) |
L10P |
probably benign |
Het |
| Vmn2r45 |
T |
C |
7: 8,481,468 (GRCm38) |
N446S |
probably damaging |
Het |
| Vps13c |
A |
T |
9: 67,913,204 (GRCm38) |
|
probably null |
Het |
| Vwa3b |
C |
T |
1: 37,154,036 (GRCm38) |
T11I |
probably benign |
Het |
| Vwf |
A |
C |
6: 125,677,970 (GRCm38) |
Q2543P |
probably damaging |
Het |
| Yap1 |
G |
A |
9: 7,934,741 (GRCm38) |
|
probably benign |
Het |
| Zfp282 |
A |
C |
6: 47,897,836 (GRCm38) |
D325A |
probably damaging |
Het |
| Zfyve9 |
T |
G |
4: 108,682,151 (GRCm38) |
Y975S |
probably damaging |
Het |
|
| Other mutations in Vmn2r103 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00333:Vmn2r103
|
APN |
17 |
19,793,102 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL00939:Vmn2r103
|
APN |
17 |
19,794,965 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01120:Vmn2r103
|
APN |
17 |
19,792,997 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL01403:Vmn2r103
|
APN |
17 |
19,792,967 (GRCm38) |
missense |
probably benign |
|
|
IGL01713:Vmn2r103
|
APN |
17 |
19,794,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01802:Vmn2r103
|
APN |
17 |
19,799,208 (GRCm38) |
missense |
probably benign |
|
|
IGL02251:Vmn2r103
|
APN |
17 |
19,793,969 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
IGL02466:Vmn2r103
|
APN |
17 |
19,773,369 (GRCm38) |
missense |
probably benign |
|
|
IGL02555:Vmn2r103
|
APN |
17 |
19,811,611 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02668:Vmn2r103
|
APN |
17 |
19,794,127 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02715:Vmn2r103
|
APN |
17 |
19,793,956 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02735:Vmn2r103
|
APN |
17 |
19,812,248 (GRCm38) |
missense |
probably benign |
0.27 |
|
IGL03101:Vmn2r103
|
APN |
17 |
19,773,520 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0003:Vmn2r103
|
UTSW |
17 |
19,811,979 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0052:Vmn2r103
|
UTSW |
17 |
19,811,641 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0375:Vmn2r103
|
UTSW |
17 |
19,793,464 (GRCm38) |
missense |
probably benign |
0.12 |
|
R0375:Vmn2r103
|
UTSW |
17 |
19,792,859 (GRCm38) |
missense |
probably benign |
0.06 |
|
R0755:Vmn2r103
|
UTSW |
17 |
19,773,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0837:Vmn2r103
|
UTSW |
17 |
19,793,927 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1345:Vmn2r103
|
UTSW |
17 |
19,794,247 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1396:Vmn2r103
|
UTSW |
17 |
19,792,968 (GRCm38) |
missense |
probably benign |
|
|
R1488:Vmn2r103
|
UTSW |
17 |
19,793,660 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1533:Vmn2r103
|
UTSW |
17 |
19,773,400 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1590:Vmn2r103
|
UTSW |
17 |
19,794,234 (GRCm38) |
missense |
probably benign |
|
|
R1928:Vmn2r103
|
UTSW |
17 |
19,811,767 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1942:Vmn2r103
|
UTSW |
17 |
19,812,300 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2071:Vmn2r103
|
UTSW |
17 |
19,793,794 (GRCm38) |
missense |
probably benign |
|
|
R2219:Vmn2r103
|
UTSW |
17 |
19,793,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2442:Vmn2r103
|
UTSW |
17 |
19,773,531 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2889:Vmn2r103
|
UTSW |
17 |
19,793,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3762:Vmn2r103
|
UTSW |
17 |
19,812,149 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4014:Vmn2r103
|
UTSW |
17 |
19,793,604 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R4331:Vmn2r103
|
UTSW |
17 |
19,794,233 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4630:Vmn2r103
|
UTSW |
17 |
19,793,696 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4631:Vmn2r103
|
UTSW |
17 |
19,793,696 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4632:Vmn2r103
|
UTSW |
17 |
19,793,696 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4660:Vmn2r103
|
UTSW |
17 |
19,811,815 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Vmn2r103
|
UTSW |
17 |
19,795,076 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4802:Vmn2r103
|
UTSW |
17 |
19,795,076 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4931:Vmn2r103
|
UTSW |
17 |
19,811,769 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4995:Vmn2r103
|
UTSW |
17 |
19,773,511 (GRCm38) |
missense |
probably benign |
0.14 |
|
R5309:Vmn2r103
|
UTSW |
17 |
19,793,034 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5312:Vmn2r103
|
UTSW |
17 |
19,793,034 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5329:Vmn2r103
|
UTSW |
17 |
19,812,171 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5611:Vmn2r103
|
UTSW |
17 |
19,793,642 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5684:Vmn2r103
|
UTSW |
17 |
19,792,989 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5715:Vmn2r103
|
UTSW |
17 |
19,794,939 (GRCm38) |
missense |
probably benign |
0.17 |
|
R5907:Vmn2r103
|
UTSW |
17 |
19,812,453 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R6029:Vmn2r103
|
UTSW |
17 |
19,794,216 (GRCm38) |
nonsense |
probably null |
|
|
R6114:Vmn2r103
|
UTSW |
17 |
19,812,325 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6285:Vmn2r103
|
UTSW |
17 |
19,812,144 (GRCm38) |
missense |
probably benign |
|
|
R6292:Vmn2r103
|
UTSW |
17 |
19,793,604 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R6334:Vmn2r103
|
UTSW |
17 |
19,794,082 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6501:Vmn2r103
|
UTSW |
17 |
19,811,904 (GRCm38) |
missense |
probably benign |
0.29 |
|
R6710:Vmn2r103
|
UTSW |
17 |
19,811,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6774:Vmn2r103
|
UTSW |
17 |
19,773,511 (GRCm38) |
missense |
probably benign |
0.14 |
|
R6981:Vmn2r103
|
UTSW |
17 |
19,793,477 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7768:Vmn2r103
|
UTSW |
17 |
19,812,052 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7816:Vmn2r103
|
UTSW |
17 |
19,794,214 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7885:Vmn2r103
|
UTSW |
17 |
19,793,123 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8002:Vmn2r103
|
UTSW |
17 |
19,799,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8031:Vmn2r103
|
UTSW |
17 |
19,793,497 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8140:Vmn2r103
|
UTSW |
17 |
19,811,796 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8186:Vmn2r103
|
UTSW |
17 |
19,811,943 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8559:Vmn2r103
|
UTSW |
17 |
19,812,384 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9413:Vmn2r103
|
UTSW |
17 |
19,811,896 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R9591:Vmn2r103
|
UTSW |
17 |
19,811,659 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R9652:Vmn2r103
|
UTSW |
17 |
19,793,765 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9680:Vmn2r103
|
UTSW |
17 |
19,799,263 (GRCm38) |
nonsense |
probably null |
|
|
R9743:Vmn2r103
|
UTSW |
17 |
19,812,213 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Vmn2r103
|
UTSW |
17 |
19,795,047 (GRCm38) |
missense |
probably benign |
0.08 |
|
| Posted On |
2013-11-05 |
Incidental Mutation