Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01404:Vwf'

79738

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vwf

Ensembl Gene

ENSMUSG00000001930

Gene Name

Von Willebrand factor

Synonyms

6820430P06Rik, B130011O06Rik

Accession Numbers

Genbank: NM_011708; MGI: 98941

Essential gene?

Probably non essential (E-score: 0.165) question?

Stock #

IGL01404

Quality Score

Status

Chromosome

Chromosomal Location

125546774-125686679 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 125677970 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Proline at position 2543 (Q2543P)

Ref Sequence

ENSEMBL: ENSMUSP00000107873 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000112254]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000112254
AA Change: Q2543P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000107873
Gene: ENSMUSG00000001930
AA Change: Q2543P

Domain	Start	End	E-Value	Type
VWD	23	181	3.43e-35	SMART
C8	221	295	1.11e-21	SMART
Pfam:TIL	298	351	6.9e-15	PFAM
VWC	353	413	8.71e-1	SMART
VWD	380	543	2.93e-52	SMART
C8	580	652	3.82e-25	SMART
Pfam:TIL	655	710	4.1e-14	PFAM
EGF_like	790	825	4.37e1	SMART
VWC	832	901	3.29e-3	SMART
VWD	859	1015	5.15e-39	SMART
C8	1056	1130	1.01e-33	SMART
Pfam:TIL	1144	1199	1.3e-9	PFAM
VWA	1278	1461	1.81e-20	SMART
low complexity region	1464	1477	N/A	INTRINSIC
VWA	1499	1672	8.43e-39	SMART
VWA	1692	1875	2.83e-31	SMART
VWC	1882	1949	2.99e0	SMART
VWD	1941	2104	5.03e-42	SMART
C8	2135	2203	1.29e-13	SMART
Pfam:TIL	2206	2257	8.3e-8	PFAM
VWC	2260	2328	3.16e-16	SMART
low complexity region	2417	2428	N/A	INTRINSIC
VWC	2434	2497	2.61e-17	SMART
VWC	2513	2577	3.37e0	SMART
VWC	2585	2647	2.55e-11	SMART
CT	2730	2815	1.37e-31	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000147101

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
PHENOTYPE: Homozygous null mutants exhibit hemostatic and thrombotic defects similar to human von Willebrand disease. Mutants have prolonged bleeding time, newborns occasionally show fatal intra-abdominal bleeding and some adults have detectable fecal occult blood. [provided by MGI curators]

Allele List at MGI

All alleles(33) : Targeted, knock-out(1) Gene trapped(32)

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2700049A03Rik	T	A	12: 71,164,378 (GRCm38)		probably null	Het
4921524L21Rik	T	C	18: 6,638,653 (GRCm38)	S351P	possibly damaging	Het
Ablim3	A	G	18: 61,871,683 (GRCm38)	Y12H	probably damaging	Het
Adam2	C	T	14: 66,077,210 (GRCm38)		probably null	Het
Adgre4	A	T	17: 55,797,639 (GRCm38)	N235I	possibly damaging	Het
Aldh3b1	A	C	19: 3,921,205 (GRCm38)	V153G	probably benign	Het
B430306N03Rik	A	G	17: 48,321,073 (GRCm38)	Y177C	probably damaging	Het
Cast	A	T	13: 74,738,287 (GRCm38)	Y249*	probably null	Het
Cfap43	T	C	19: 47,795,666 (GRCm38)	D476G	probably benign	Het
Cpa4	T	C	6: 30,581,702 (GRCm38)	I216T	possibly damaging	Het
Cpeb3	T	C	19: 37,088,548 (GRCm38)	D407G	probably benign	Het
Ctnnal1	T	C	4: 56,829,590 (GRCm38)	D413G	probably damaging	Het
Cyb5a	A	G	18: 84,877,860 (GRCm38)	S84G	probably benign	Het
Dpy19l4	C	A	4: 11,273,006 (GRCm38)		probably null	Het
Erbin	A	T	13: 103,839,464 (GRCm38)	S641T	probably damaging	Het
Espn	T	A	4: 152,138,444 (GRCm38)	T326S	probably benign	Het
Extl1	T	C	4: 134,359,203 (GRCm38)	M514V	probably benign	Het
Fancc	G	A	13: 63,361,638 (GRCm38)	L134F	probably damaging	Het
Fis1	C	T	5: 136,965,974 (GRCm38)	A90V	probably benign	Het
Gdi2	A	G	13: 3,564,611 (GRCm38)	T319A	probably benign	Het
Gjc3	A	G	5: 137,957,858 (GRCm38)	F55S	probably damaging	Het
Gm10762	C	T	2: 128,967,085 (GRCm38)		probably benign	Het
Got1	A	G	19: 43,504,609 (GRCm38)	I291T	possibly damaging	Het
Gpr179	C	A	11: 97,338,186 (GRCm38)	G1048*	probably null	Het
Ino80	T	A	2: 119,456,718 (GRCm38)	D56V	possibly damaging	Het
Kcp	C	A	6: 29,496,639 (GRCm38)	C624F	probably damaging	Het
Kctd1	T	A	18: 14,969,553 (GRCm38)	Q857L	probably damaging	Het
Lins1	G	A	7: 66,713,928 (GRCm38)	V524I	probably damaging	Het
Lrp1	A	T	10: 127,595,032 (GRCm38)	Y383N	probably damaging	Het
Mgam	A	C	6: 40,644,945 (GRCm38)	K84Q	probably benign	Het
Mib2	T	A	4: 155,654,936 (GRCm38)	E862V	probably damaging	Het
Myh1	G	T	11: 67,222,151 (GRCm38)	R1827L	possibly damaging	Het
Myh10	T	C	11: 68,752,040 (GRCm38)		probably null	Het
Myo1e	A	G	9: 70,337,766 (GRCm38)	Y382C	probably benign	Het
Nktr	G	A	9: 121,741,152 (GRCm38)		probably null	Het
Nlrc4	A	G	17: 74,445,711 (GRCm38)	I559T	probably damaging	Het
Nod2	A	T	8: 88,663,736 (GRCm38)	M224L	probably benign	Het
Olfr175-ps1	G	A	16: 58,824,595 (GRCm38)	T38I	probably damaging	Het
Olfr658	A	T	7: 104,644,480 (GRCm38)	Y295*	probably null	Het
Olfr984	A	G	9: 40,101,262 (GRCm38)	I76T	probably benign	Het
Pex7	G	T	10: 19,894,811 (GRCm38)		probably benign	Het
Ptprb	A	T	10: 116,339,436 (GRCm38)	D1112V	probably benign	Het
Rubcn	G	A	16: 32,827,296 (GRCm38)	T636M	probably damaging	Het
Scn5a	A	C	9: 119,486,470 (GRCm38)	L1724R	probably damaging	Het
Sec14l2	T	C	11: 4,116,710 (GRCm38)	D34G	possibly damaging	Het
Serpina3k	A	G	12: 104,340,623 (GRCm38)	D38G	probably benign	Het
Sh3bgr	A	C	16: 96,206,490 (GRCm38)	K18N	probably damaging	Het
Sh3bp5l	A	T	11: 58,346,060 (GRCm38)	H281L	probably benign	Het
Slc28a2	T	G	2: 122,452,057 (GRCm38)	I287M	probably damaging	Het
Slc2a1	T	A	4: 119,132,238 (GRCm38)	M45K	possibly damaging	Het
Syt11	A	G	3: 88,762,216 (GRCm38)	I123T	probably benign	Het
Tfg	C	A	16: 56,694,493 (GRCm38)		probably benign	Het
Tmem177	T	C	1: 119,910,061 (GRCm38)	D296G	probably damaging	Het
Trabd2b	A	G	4: 114,599,956 (GRCm38)	I357V	probably benign	Het
Trp63	C	A	16: 25,820,385 (GRCm38)		probably benign	Het
Ugt1a8	T	C	1: 88,087,895 (GRCm38)	L10P	probably benign	Het
Vmn2r103	A	G	17: 19,812,434 (GRCm38)	I823M	probably damaging	Het
Vmn2r45	T	C	7: 8,481,468 (GRCm38)	N446S	probably damaging	Het
Vps13c	A	T	9: 67,913,204 (GRCm38)		probably null	Het
Vwa3b	C	T	1: 37,154,036 (GRCm38)	T11I	probably benign	Het
Yap1	G	A	9: 7,934,741 (GRCm38)		probably benign	Het
Zfp282	A	C	6: 47,897,836 (GRCm38)	D325A	probably damaging	Het
Zfyve9	T	G	4: 108,682,151 (GRCm38)	Y975S	probably damaging	Het

Other mutations in Vwf

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00489:Vwf	APN	6	125,658,872 (GRCm38)	missense	unknown
IGL00561:Vwf	APN	6	125,642,721 (GRCm38)	missense	possibly damaging	0.88
IGL01104:Vwf	APN	6	125,683,556 (GRCm38)	missense	probably damaging	1.00
IGL01539:Vwf	APN	6	125,590,262 (GRCm38)	missense	possibly damaging	0.85
IGL01550:Vwf	APN	6	125,679,289 (GRCm38)	missense	probably benign	0.00
IGL01563:Vwf	APN	6	125,591,165 (GRCm38)	missense	probably damaging	1.00
IGL01637:Vwf	APN	6	125,645,736 (GRCm38)	missense	probably damaging	1.00
IGL01720:Vwf	APN	6	125,642,835 (GRCm38)	missense	possibly damaging	0.69
IGL01834:Vwf	APN	6	125,590,170 (GRCm38)	splice site	probably benign
IGL02103:Vwf	APN	6	125,646,355 (GRCm38)	missense	probably damaging	1.00
IGL02120:Vwf	APN	6	125,616,034 (GRCm38)	missense	probably benign	0.26
IGL02174:Vwf	APN	6	125,555,395 (GRCm38)	missense	probably damaging	1.00
IGL02203:Vwf	APN	6	125,642,406 (GRCm38)	missense	probably damaging	1.00
IGL02420:Vwf	APN	6	125,677,916 (GRCm38)	missense	probably benign	0.00
IGL02723:Vwf	APN	6	125,642,930 (GRCm38)	missense	possibly damaging	0.85
IGL02818:Vwf	APN	6	125,663,548 (GRCm38)	missense	probably benign
IGL02931:Vwf	APN	6	125,615,968 (GRCm38)	missense	possibly damaging	0.68
IGL03015:Vwf	APN	6	125,684,138 (GRCm38)	splice site	probably benign
IGL03038:Vwf	APN	6	125,604,157 (GRCm38)	missense	possibly damaging	0.92
IGL03060:Vwf	APN	6	125,663,560 (GRCm38)	missense	probably damaging	1.00
IGL03114:Vwf	APN	6	125,599,363 (GRCm38)	nonsense	probably null
IGL03266:Vwf	APN	6	125,678,077 (GRCm38)	splice site	probably benign
gingerman	UTSW	6	125,662,963 (GRCm38)	critical splice acceptor site	probably null
R0605_vwf_644	UTSW	6	125,685,837 (GRCm38)	missense	probably benign	0.02
R1575_Vwf_091	UTSW	6	125,663,571 (GRCm38)	nonsense	probably null
R1628_Vwf_608	UTSW	6	125,647,738 (GRCm38)	unclassified	probably benign
R1669_Vwf_448	UTSW	6	125,647,906 (GRCm38)	missense	possibly damaging	0.92
R1833_Vwf_948	UTSW	6	125,642,037 (GRCm38)	missense	probably benign	0.14
R2130_vwf_946	UTSW	6	125,657,057 (GRCm38)	missense	probably damaging	1.00
R6360_Vwf_065	UTSW	6	125,683,526 (GRCm38)	missense	probably benign	0.13
R7900_Vwf_938	UTSW	6	125,628,476 (GRCm38)	critical splice donor site	probably null
Russiahouse	UTSW	6	125,639,341 (GRCm38)	nonsense	probably null
B5639:Vwf	UTSW	6	125,642,984 (GRCm38)	missense	probably damaging	1.00
R0025:Vwf	UTSW	6	125,682,812 (GRCm38)	missense	probably benign	0.05
R0025:Vwf	UTSW	6	125,682,812 (GRCm38)	missense	probably benign	0.05
R0087:Vwf	UTSW	6	125,645,954 (GRCm38)	missense	probably benign	0.03
R0194:Vwf	UTSW	6	125,643,297 (GRCm38)	missense	probably benign
R0206:Vwf	UTSW	6	125,637,456 (GRCm38)	missense	probably damaging	1.00
R0233:Vwf	UTSW	6	125,686,510 (GRCm38)	missense	possibly damaging	0.91
R0233:Vwf	UTSW	6	125,686,510 (GRCm38)	missense	possibly damaging	0.91
R0390:Vwf	UTSW	6	125,626,361 (GRCm38)	nonsense	probably null
R0427:Vwf	UTSW	6	125,673,939 (GRCm38)	missense	probably benign
R0437:Vwf	UTSW	6	125,566,318 (GRCm38)	missense	probably damaging	1.00
R0470:Vwf	UTSW	6	125,628,428 (GRCm38)	missense	possibly damaging	0.70
R0499:Vwf	UTSW	6	125,638,114 (GRCm38)	missense	probably benign	0.10
R0554:Vwf	UTSW	6	125,642,781 (GRCm38)	missense	probably benign	0.13
R0605:Vwf	UTSW	6	125,685,837 (GRCm38)	missense	probably benign	0.02
R0711:Vwf	UTSW	6	125,626,271 (GRCm38)	missense	probably benign	0.01
R0723:Vwf	UTSW	6	125,566,262 (GRCm38)	missense	probably benign	0.01
R0973:Vwf	UTSW	6	125,643,006 (GRCm38)	missense	probably damaging	1.00
R1054:Vwf	UTSW	6	125,590,227 (GRCm38)	missense	probably damaging	1.00
R1115:Vwf	UTSW	6	125,655,065 (GRCm38)	missense	unknown
R1156:Vwf	UTSW	6	125,637,488 (GRCm38)	missense	probably damaging	1.00
R1191:Vwf	UTSW	6	125,599,252 (GRCm38)	missense	probably damaging	1.00
R1240:Vwf	UTSW	6	125,603,308 (GRCm38)	splice site	probably null
R1398:Vwf	UTSW	6	125,603,457 (GRCm38)	missense	probably benign	0.02
R1435:Vwf	UTSW	6	125,642,249 (GRCm38)	nonsense	probably null
R1528:Vwf	UTSW	6	125,608,291 (GRCm38)	missense	possibly damaging	0.69
R1575:Vwf	UTSW	6	125,663,571 (GRCm38)	nonsense	probably null
R1575:Vwf	UTSW	6	125,655,251 (GRCm38)	missense	unknown
R1628:Vwf	UTSW	6	125,647,738 (GRCm38)	unclassified	probably benign
R1669:Vwf	UTSW	6	125,647,906 (GRCm38)	missense	possibly damaging	0.92
R1699:Vwf	UTSW	6	125,685,900 (GRCm38)	missense	possibly damaging	0.74
R1699:Vwf	UTSW	6	125,643,069 (GRCm38)	missense	probably damaging	1.00
R1725:Vwf	UTSW	6	125,646,282 (GRCm38)	missense	probably benign	0.05
R1742:Vwf	UTSW	6	125,667,550 (GRCm38)	missense	probably benign	0.02
R1809:Vwf	UTSW	6	125,590,175 (GRCm38)	splice site	probably benign
R1833:Vwf	UTSW	6	125,642,037 (GRCm38)	missense	probably benign	0.14
R1866:Vwf	UTSW	6	125,667,529 (GRCm38)	missense	possibly damaging	0.62
R1870:Vwf	UTSW	6	125,642,939 (GRCm38)	missense	probably damaging	1.00
R1874:Vwf	UTSW	6	125,628,372 (GRCm38)	missense	probably benign	0.00
R1941:Vwf	UTSW	6	125,639,279 (GRCm38)	missense	possibly damaging	0.64
R2061:Vwf	UTSW	6	125,591,188 (GRCm38)	missense	probably damaging	0.98
R2103:Vwf	UTSW	6	125,646,330 (GRCm38)	missense	probably benign	0.31
R2104:Vwf	UTSW	6	125,646,330 (GRCm38)	missense	probably benign	0.31
R2130:Vwf	UTSW	6	125,657,057 (GRCm38)	missense	probably damaging	1.00
R2159:Vwf	UTSW	6	125,626,341 (GRCm38)	missense	probably damaging	0.99
R2178:Vwf	UTSW	6	125,642,132 (GRCm38)	missense	possibly damaging	0.90
R2656:Vwf	UTSW	6	125,555,361 (GRCm38)	missense	probably benign	0.00
R2913:Vwf	UTSW	6	125,685,846 (GRCm38)	missense	probably benign	0.08
R2917:Vwf	UTSW	6	125,608,143 (GRCm38)	missense	probably benign	0.07
R3726:Vwf	UTSW	6	125,677,948 (GRCm38)	utr 3 prime	probably benign
R3735:Vwf	UTSW	6	125,588,613 (GRCm38)	missense	probably damaging	1.00
R3774:Vwf	UTSW	6	125,649,099 (GRCm38)	splice site	probably null
R3934:Vwf	UTSW	6	125,555,499 (GRCm38)	missense	probably damaging	1.00
R4291:Vwf	UTSW	6	125,642,322 (GRCm38)	missense	probably damaging	1.00
R4384:Vwf	UTSW	6	125,655,116 (GRCm38)	missense	unknown
R4743:Vwf	UTSW	6	125,684,091 (GRCm38)	critical splice acceptor site	probably null
R4760:Vwf	UTSW	6	125,570,604 (GRCm38)	missense	probably damaging	1.00
R4776:Vwf	UTSW	6	125,566,305 (GRCm38)	missense	possibly damaging	0.53
R4791:Vwf	UTSW	6	125,643,363 (GRCm38)	missense
R4871:Vwf	UTSW	6	125,686,462 (GRCm38)	missense	probably benign	0.25
R4894:Vwf	UTSW	6	125,645,934 (GRCm38)	nonsense	probably null
R4963:Vwf	UTSW	6	125,667,483 (GRCm38)	nonsense	probably null
R5010:Vwf	UTSW	6	125,566,257 (GRCm38)	missense	probably benign	0.15
R5289:Vwf	UTSW	6	125,667,510 (GRCm38)	utr 3 prime	probably benign
R5512:Vwf	UTSW	6	125,673,887 (GRCm38)	utr 3 prime	probably benign
R5523:Vwf	UTSW	6	125,643,042 (GRCm38)	missense
R5642:Vwf	UTSW	6	125,603,418 (GRCm38)	missense
R5860:Vwf	UTSW	6	125,679,265 (GRCm38)	utr 3 prime	probably benign
R5860:Vwf	UTSW	6	125,643,090 (GRCm38)	missense
R5896:Vwf	UTSW	6	125,678,762 (GRCm38)	critical splice acceptor site	probably null
R5926:Vwf	UTSW	6	125,604,174 (GRCm38)	missense	probably damaging	1.00
R5976:Vwf	UTSW	6	125,603,463 (GRCm38)	missense
R6053:Vwf	UTSW	6	125,600,665 (GRCm38)	missense	probably benign	0.21
R6151:Vwf	UTSW	6	125,657,065 (GRCm38)	missense	unknown
R6179:Vwf	UTSW	6	125,649,289 (GRCm38)	missense	unknown
R6181:Vwf	UTSW	6	125,566,146 (GRCm38)	missense	probably damaging	0.98
R6234:Vwf	UTSW	6	125,657,165 (GRCm38)	missense	unknown
R6360:Vwf	UTSW	6	125,683,526 (GRCm38)	missense	probably benign	0.13
R6412:Vwf	UTSW	6	125,679,316 (GRCm38)	missense	probably benign	0.00
R6464:Vwf	UTSW	6	125,639,400 (GRCm38)	critical splice donor site	probably null
R6522:Vwf	UTSW	6	125,662,963 (GRCm38)	critical splice acceptor site	probably null
R6766:Vwf	UTSW	6	125,639,376 (GRCm38)	missense	unknown
R6856:Vwf	UTSW	6	125,642,150 (GRCm38)	nonsense	probably null
R6877:Vwf	UTSW	6	125,657,201 (GRCm38)	missense	possibly damaging	0.48
R6896:Vwf	UTSW	6	125,566,194 (GRCm38)	missense	probably damaging	1.00
R7113:Vwf	UTSW	6	125,655,044 (GRCm38)	missense
R7287:Vwf	UTSW	6	125,637,467 (GRCm38)	missense
R7359:Vwf	UTSW	6	125,566,257 (GRCm38)	missense
R7509:Vwf	UTSW	6	125,642,169 (GRCm38)	missense
R7519:Vwf	UTSW	6	125,667,543 (GRCm38)	missense
R7545:Vwf	UTSW	6	125,614,097 (GRCm38)	missense
R7549:Vwf	UTSW	6	125,626,267 (GRCm38)	missense
R7593:Vwf	UTSW	6	125,647,768 (GRCm38)	missense
R7635:Vwf	UTSW	6	125,682,734 (GRCm38)	missense
R7793:Vwf	UTSW	6	125,686,520 (GRCm38)	missense
R7802:Vwf	UTSW	6	125,666,677 (GRCm38)	missense
R7824:Vwf	UTSW	6	125,658,815 (GRCm38)	missense
R7849:Vwf	UTSW	6	125,656,803 (GRCm38)	missense
R7900:Vwf	UTSW	6	125,628,476 (GRCm38)	critical splice donor site	probably null
R7919:Vwf	UTSW	6	125,647,859 (GRCm38)	missense
R7966:Vwf	UTSW	6	125,639,341 (GRCm38)	nonsense	probably null
R8101:Vwf	UTSW	6	125,570,559 (GRCm38)	nonsense	probably null
R8162:Vwf	UTSW	6	125,645,836 (GRCm38)	splice site	probably null
R8345:Vwf	UTSW	6	125,679,302 (GRCm38)	missense
R8853:Vwf	UTSW	6	125,657,264 (GRCm38)	missense
R9027:Vwf	UTSW	6	125,666,663 (GRCm38)	missense
R9065:Vwf	UTSW	6	125,646,299 (GRCm38)	missense
R9068:Vwf	UTSW	6	125,648,829 (GRCm38)	unclassified	probably benign
R9128:Vwf	UTSW	6	125,642,730 (GRCm38)	missense
R9136:Vwf	UTSW	6	125,599,393 (GRCm38)	splice site	probably benign
R9164:Vwf	UTSW	6	125,565,843 (GRCm38)	missense
R9177:Vwf	UTSW	6	125,604,291 (GRCm38)	missense
R9334:Vwf	UTSW	6	125,677,946 (GRCm38)	missense
R9508:Vwf	UTSW	6	125,555,508 (GRCm38)	missense
R9553:Vwf	UTSW	6	125,600,699 (GRCm38)	missense
R9660:Vwf	UTSW	6	125,591,707 (GRCm38)	missense	possibly damaging	0.61
R9706:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9708:Vwf	UTSW	6	125,657,090 (GRCm38)	missense
R9712:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9714:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9728:Vwf	UTSW	6	125,591,707 (GRCm38)	missense	possibly damaging	0.61
R9758:Vwf	UTSW	6	125,626,267 (GRCm38)	missense
X0021:Vwf	UTSW	6	125,646,331 (GRCm38)	missense	probably damaging	1.00
X0065:Vwf	UTSW	6	125,603,433 (GRCm38)	missense	probably null	0.05
Z1176:Vwf	UTSW	6	125,603,308 (GRCm38)	splice site	probably null
Z1176:Vwf	UTSW	6	125,591,231 (GRCm38)	missense

Posted On

2013-11-05