Incidental Mutation 'IGL01410:Vmn1r192'
ID79953
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r192
Ensembl Gene ENSMUSG00000099787
Gene Namevomeronasal 1 receptor 192
SynonymsV1ri1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.082) question?
Stock #IGL01410
Quality Score
Status
Chromosome13
Chromosomal Location22187075-22188141 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 22187909 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Proline at position 47 (L47P)
Ref Sequence ENSEMBL: ENSMUSP00000072426 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072632]
Predicted Effect probably damaging
Transcript: ENSMUST00000072632
AA Change: L47P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000072426
Gene: ENSMUSG00000099787
AA Change: L47P

DomainStartEndE-ValueType
Pfam:TAS2R 1 293 2.6e-10 PFAM
Pfam:V1R 37 299 1.1e-35 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 60 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aox1 T A 1: 58,106,025 probably null Het
Aspm C T 1: 139,482,444 T1359I probably benign Het
Atp13a2 A G 4: 140,992,198 D26G probably benign Het
Atrnl1 G A 19: 58,131,104 A1343T probably damaging Het
Ccsap A C 8: 123,859,230 S61A probably damaging Het
Cdh1 A T 8: 106,657,853 M318L probably benign Het
Cfap69 G A 5: 5,646,979 P106S probably damaging Het
Cfp G A X: 20,929,724 T88I probably damaging Het
Chst1 A T 2: 92,614,130 I316F probably damaging Het
Col7a1 A T 9: 108,964,618 D1382V unknown Het
Cr2 T A 1: 195,163,234 M514L possibly damaging Het
Cubn G A 2: 13,465,908 H558Y probably benign Het
Cul9 A T 17: 46,528,646 M802K probably damaging Het
Dennd2d A T 3: 106,491,226 I169L probably damaging Het
Dnah11 T A 12: 118,047,256 K162* probably null Het
Dnah3 T A 7: 119,967,720 T2428S possibly damaging Het
Dock11 T A X: 36,037,643 H1284Q probably damaging Het
Flrt2 T A 12: 95,779,192 D101E probably damaging Het
Gabrr2 G A 4: 33,085,626 V349M probably damaging Het
Gli2 C A 1: 118,836,891 V1177L probably benign Het
Gm16506 A G 14: 43,724,173 Y206H probably benign Het
Gm1966 C T 7: 106,603,051 noncoding transcript Het
Gm5612 C T 9: 18,427,573 probably benign Het
Heg1 C T 16: 33,725,566 T460I possibly damaging Het
Lgals9 T G 11: 78,973,151 D56A probably damaging Het
Lpgat1 A T 1: 191,776,432 probably null Het
Megf6 T A 4: 154,252,563 probably null Het
Megf8 G A 7: 25,359,871 M2265I probably benign Het
Memo1 G A 17: 74,241,981 R121* probably null Het
Morc1 T C 16: 48,612,314 V715A probably benign Het
Mycbp2 A T 14: 103,229,492 probably null Het
Ncapg2 T A 12: 116,424,650 V318D possibly damaging Het
Ndst1 T C 18: 60,700,445 Y498C probably damaging Het
Nod1 C T 6: 54,944,356 A326T probably damaging Het
Olfr1206 T A 2: 88,865,520 M305K probably benign Het
Olfr697 A G 7: 106,741,499 V145A probably benign Het
Peg3 T C 7: 6,707,625 S1533G probably benign Het
Pgc G T 17: 47,734,240 G361V probably damaging Het
Phka1 C T X: 102,586,106 R477H probably damaging Het
Plagl2 C T 2: 153,232,654 R109Q probably damaging Het
Prr36 T A 8: 4,216,230 I107F probably benign Het
Ptpdc1 T A 13: 48,586,604 R450S probably damaging Het
Ptprb A T 10: 116,302,274 D361V possibly damaging Het
Rbm44 A G 1: 91,168,829 D970G probably benign Het
Scrn2 T G 11: 97,030,570 V52G probably benign Het
Sdk1 C T 5: 142,212,120 T2176I probably benign Het
Serpina1d T A 12: 103,763,734 E396D probably benign Het
Slc38a5 A C X: 8,279,831 Q465P probably benign Het
Slc38a5 G T X: 8,279,832 Q465H probably benign Het
Smarca1 T C X: 47,892,378 T48A possibly damaging Het
Trak2 A T 1: 58,923,607 I132N probably damaging Het
Trank1 T C 9: 111,365,259 S784P probably benign Het
Trank1 A G 9: 111,365,049 T714A probably benign Het
Trp53i13 G A 11: 77,508,257 probably benign Het
Trrap A C 5: 144,831,021 D2596A probably benign Het
Ttyh1 A T 7: 4,124,657 T19S probably damaging Het
Tyk2 C T 9: 21,109,364 V947M probably damaging Het
Ugt2b34 G A 5: 86,892,830 A411V possibly damaging Het
Virma T A 4: 11,518,929 Y725* probably null Het
Vmn2r74 T C 7: 85,961,292 D64G possibly damaging Het
Other mutations in Vmn1r192
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01869:Vmn1r192 APN 13 22187580 missense probably damaging 1.00
R0975:Vmn1r192 UTSW 13 22187463 missense probably damaging 1.00
R1751:Vmn1r192 UTSW 13 22187271 missense probably benign 0.08
R1767:Vmn1r192 UTSW 13 22187271 missense probably benign 0.08
R1880:Vmn1r192 UTSW 13 22187594 missense probably benign 0.12
R1881:Vmn1r192 UTSW 13 22187594 missense probably benign 0.12
R2113:Vmn1r192 UTSW 13 22187630 missense possibly damaging 0.67
R4290:Vmn1r192 UTSW 13 22187295 missense probably damaging 1.00
R4292:Vmn1r192 UTSW 13 22187295 missense probably damaging 1.00
R4294:Vmn1r192 UTSW 13 22187295 missense probably damaging 1.00
R4295:Vmn1r192 UTSW 13 22187295 missense probably damaging 1.00
R4921:Vmn1r192 UTSW 13 22187480 missense probably damaging 1.00
R5377:Vmn1r192 UTSW 13 22187631 missense probably benign 0.01
R5569:Vmn1r192 UTSW 13 22187214 missense possibly damaging 0.91
R6181:Vmn1r192 UTSW 13 22187282 missense probably damaging 1.00
R6455:Vmn1r192 UTSW 13 22187830 missense probably benign 0.08
R6860:Vmn1r192 UTSW 13 22187952 missense probably benign
R7246:Vmn1r192 UTSW 13 22187774 missense probably damaging 1.00
R7762:Vmn1r192 UTSW 13 22187675 missense probably damaging 0.97
R8066:Vmn1r192 UTSW 13 22187395 nonsense probably null
Posted On2013-11-05