Incidental Mutation 'R0931:Klri1'
ID80879
Institutional Source Beutler Lab
Gene Symbol Klri1
Ensembl Gene ENSMUSG00000067610
Gene Namekiller cell lectin-like receptor family I member 1
Synonyms
MMRRC Submission 039075-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.066) question?
Stock #R0931 (G1)
Quality Score225
Status Validated
Chromosome6
Chromosomal Location129697218-129717132 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 129697418 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000085362 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088046]
Predicted Effect probably benign
Transcript: ENSMUST00000088046
SMART Domains Protein: ENSMUSP00000085362
Gene: ENSMUSG00000067610

DomainStartEndE-ValueType
transmembrane domain 78 100 N/A INTRINSIC
CLECT 132 245 3.32e-7 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000205221
Coding Region Coverage
  • 1x: 99.4%
  • 3x: 98.9%
  • 10x: 97.7%
  • 20x: 96.0%
Validation Efficiency 100% (42/42)
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamtsl1 G A 4: 86,249,847 A476T probably benign Het
Aknad1 T C 3: 108,752,023 S118P probably damaging Het
Arhgap20 A G 9: 51,816,741 T85A probably benign Het
Astn2 A G 4: 65,648,293 L824P probably damaging Het
Ccr1 C A 9: 123,963,790 K234N probably damaging Het
Cfap46 T C 7: 139,655,841 R203G probably damaging Het
Col8a1 A G 16: 57,628,568 I193T unknown Het
Cpa2 T C 6: 30,552,071 probably benign Het
Crabp1 T C 9: 54,768,433 L100P possibly damaging Het
Cspp1 A T 1: 10,104,286 R655W probably damaging Het
Ddx1 A T 12: 13,237,817 probably benign Het
Dnah7b T G 1: 46,099,612 probably benign Het
Dzip3 A G 16: 48,951,558 S583P probably damaging Het
Exosc1 A G 19: 41,933,237 probably benign Het
Fam160a1 A G 3: 85,673,243 S552P probably benign Het
Gas7 A T 11: 67,652,925 probably benign Het
Gm996 T C 2: 25,578,489 E470G possibly damaging Het
Gss A T 2: 155,567,689 probably benign Het
Hdhd3 G A 4: 62,499,520 R140* probably null Het
Irx2 T A 13: 72,631,556 S320T possibly damaging Het
Kcnf1 T C 12: 17,175,141 S360G possibly damaging Het
Klk1b4 T C 7: 44,211,056 L166P probably damaging Het
Mettl27 T C 5: 134,934,431 probably benign Het
Myrfl T A 10: 116,839,449 H193L probably benign Het
Nbas C T 12: 13,331,114 probably benign Het
Olfr455 C A 6: 42,538,086 R312L probably benign Het
Olfr691 A T 7: 105,337,529 Y62* probably null Het
Papolg A G 11: 23,882,257 I177T probably damaging Het
Pdcd1 A G 1: 94,039,513 V220A probably benign Het
Psmc1 T C 12: 100,119,082 L234P probably damaging Het
Rasa2 A T 9: 96,552,404 M610K possibly damaging Het
Ryr3 A G 2: 112,653,702 F3930S probably damaging Het
Sacs G A 14: 61,203,495 V997I probably benign Het
Setdb2 A G 14: 59,423,496 probably benign Het
Ssu2 C A 6: 112,384,398 L32F probably damaging Het
Taar1 A T 10: 23,921,283 N293I probably damaging Het
Ttn A G 2: 76,781,502 probably benign Het
Vmn2r49 T C 7: 9,986,398 M389V possibly damaging Het
Wdr7 T C 18: 63,865,300 V1106A probably benign Het
Zfp324 A G 7: 12,966,258 I15V probably benign Het
Other mutations in Klri1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01328:Klri1 APN 6 129698837 missense probably damaging 1.00
IGL01380:Klri1 APN 6 129698798 missense probably benign 0.01
IGL01608:Klri1 APN 6 129698167 missense possibly damaging 0.50
IGL01778:Klri1 APN 6 129717047 missense possibly damaging 0.59
R1646:Klri1 UTSW 6 129703336 missense probably benign 0.00
R1649:Klri1 UTSW 6 129698241 missense probably benign
R1746:Klri1 UTSW 6 129698155 splice site probably null
R1960:Klri1 UTSW 6 129697384 missense probably benign 0.02
R6561:Klri1 UTSW 6 129717001 missense probably benign 0.03
R6773:Klri1 UTSW 6 129703547 missense possibly damaging 0.67
X0021:Klri1 UTSW 6 129716911 missense probably benign 0.25
Predicted Primers PCR Primer
(F):5'- ACTGGGTGAGGCTGCATCTCT -3'
(R):5'- GCAGACAGTGTAGGATTAGCTTGTGTGT -3'

Sequencing Primer
(F):5'- cttttgacccccacatgcTC -3'
(R):5'- TGTGTGATGTTGTCTAGTATCGG -3'
Posted On2013-11-07