Incidental Mutation 'R0906:Gm6729'
ID 83329
Institutional Source Beutler Lab
Gene Symbol Gm6729
Ensembl Gene ENSMUSG00000090816
Gene Name predicted gene 6729
MMRRC Submission 039064-MU
Accession Numbers
Essential gene? Probably non essential (E-score: 0.076) question?
Stock # R0906 (G1)
Quality Score 225
Status Validated
Chromosome 10
Chromosomal Location 86362161-86377447 bp(-) (GRCm39)
Type of Mutation unclassified
DNA Base Change (assembly) T to C at 86376456 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000165173
SMART Domains Protein: ENSMUSP00000133178
Gene: ENSMUSG00000090816

S_TKc 14 262 4.3e-87 SMART
UBA 276 313 2.99e-4 SMART
low complexity region 327 341 N/A INTRINSIC
low complexity region 450 465 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219485
Meta Mutation Damage Score 0.0869 question?
Coding Region Coverage
  • 1x: 99.5%
  • 3x: 99.0%
  • 10x: 97.8%
  • 20x: 96.3%
Validation Efficiency 100% (33/33)
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
AA986860 T A 1: 130,665,430 (GRCm39) probably benign Het
Atp7b T C 8: 22,517,842 (GRCm39) H332R probably benign Het
Bace2 C T 16: 97,158,141 (GRCm39) P47L possibly damaging Het
Cyp2c39 A G 19: 39,499,315 (GRCm39) M1V probably null Het
Dcbld2 A G 16: 58,275,610 (GRCm39) E442G probably damaging Het
Gm14496 A G 2: 181,642,308 (GRCm39) T660A probably damaging Het
Gm4945 A C 17: 47,353,796 (GRCm39) noncoding transcript Het
Golga1 G A 2: 38,937,655 (GRCm39) R204W probably damaging Het
Guf1 T C 5: 69,723,729 (GRCm39) I348T probably damaging Het
Htra4 T A 8: 25,527,160 (GRCm39) I212L probably benign Het
Itih5 G A 2: 10,253,999 (GRCm39) R750Q probably benign Het
Lgalsl2 T C 7: 5,362,828 (GRCm39) I153T probably damaging Het
Lgr6 C T 1: 134,921,748 (GRCm39) A199T probably damaging Het
Naip2 C T 13: 100,298,368 (GRCm39) G556D probably benign Het
Naip2 T C 13: 100,298,362 (GRCm39) E558G probably benign Het
Nsd1 T C 13: 55,425,403 (GRCm39) V1520A probably benign Het
Nuak1 C T 10: 84,211,144 (GRCm39) V315I probably damaging Het
Nup205 G T 6: 35,213,827 (GRCm39) G1740C probably damaging Het
Or1r1 G C 11: 73,874,685 (GRCm39) L250V probably damaging Het
Pclo T C 5: 14,726,700 (GRCm39) probably benign Het
Pik3r6 T C 11: 68,426,927 (GRCm39) probably benign Het
Pikfyve T A 1: 65,292,556 (GRCm39) F1336I probably damaging Het
Pla2r1 A G 2: 60,345,291 (GRCm39) I355T possibly damaging Het
Rgs22 A T 15: 36,104,048 (GRCm39) probably benign Het
Sec63 T A 10: 42,677,924 (GRCm39) M312K probably damaging Het
Slc2a5 T C 4: 150,227,287 (GRCm39) I401T probably benign Het
Slc9a8 G T 2: 167,276,787 (GRCm39) probably benign Het
Stab1 T C 14: 30,867,206 (GRCm39) E1718G probably benign Het
Terb1 A T 8: 105,179,268 (GRCm39) I640N probably damaging Het
Tmem217 A G 17: 29,745,490 (GRCm39) L80P probably damaging Het
Topbp1 C T 9: 103,205,792 (GRCm39) P810L probably benign Het
Ttbk2 G A 2: 120,614,262 (GRCm39) R151C probably damaging Het
Vmn2r88 T G 14: 51,655,666 (GRCm39) L626R probably damaging Het
Other mutations in Gm6729
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1034:Gm6729 UTSW 10 86,375,890 (GRCm39) unclassified noncoding transcript
R1052:Gm6729 UTSW 10 86,376,799 (GRCm39) unclassified noncoding transcript
R1523:Gm6729 UTSW 10 86,376,039 (GRCm39) unclassified noncoding transcript
R1922:Gm6729 UTSW 10 86,376,782 (GRCm39) unclassified noncoding transcript
R3498:Gm6729 UTSW 10 86,376,582 (GRCm39) unclassified noncoding transcript
R4133:Gm6729 UTSW 10 86,377,030 (GRCm39) unclassified noncoding transcript
R4193:Gm6729 UTSW 10 86,376,483 (GRCm39) unclassified noncoding transcript
R4940:Gm6729 UTSW 10 86,376,252 (GRCm39) unclassified noncoding transcript
X0028:Gm6729 UTSW 10 86,376,648 (GRCm39) unclassified noncoding transcript
Predicted Primers PCR Primer

Sequencing Primer
Posted On 2013-11-08