Mutagenetix > Incidental Mutation

Incidental Mutation 'R0906:Gm4945'

83341

Institutional Source

Beutler Lab

Gene Symbol

Gm4945

Ensembl Gene

ENSMUSG00000062472

Gene Name

predicted gene 4945

Synonyms

MMRRC Submission

039064-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.307) question?

Stock #

R0906 (G1)

Quality Score

160

Status

Validated

Chromosome

Chromosomal Location

47042587-47043039 bp(-) (GRCm38)

Type of Mutation

exon

DNA Base Change (assembly)

A to C at 47042870 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000075152

SMART Domains

Protein: ENSMUSP00000074649
Gene: ENSMUSG00000062472

Domain	Start	End	E-Value	Type
Pfam:Ribosomal_L29e	3	42	2.6e-29	PFAM
low complexity region	117	143	N/A	INTRINSIC

Coding Region Coverage

1x: 99.5%
3x: 99.0%
10x: 97.8%
20x: 96.3%

Validation Efficiency

100% (33/33)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AA986860	T	A	1: 130,737,693 (GRCm38)		probably benign	Het
Atp7b	T	C	8: 22,027,826 (GRCm38)	H332R	probably benign	Het
Bace2	C	T	16: 97,356,941 (GRCm38)	P47L	possibly damaging	Het
Cyp2c39	A	G	19: 39,510,871 (GRCm38)	M1V	probably null	Het
Dcbld2	A	G	16: 58,455,247 (GRCm38)	E442G	probably damaging	Het
Gm14496	A	G	2: 182,000,515 (GRCm38)	T660A	probably damaging	Het
Gm5065	T	C	7: 5,359,829 (GRCm38)	I153T	probably damaging	Het
Gm6729	T	C	10: 86,540,592 (GRCm38)		noncoding transcript	Het
Golga1	G	A	2: 39,047,643 (GRCm38)	R204W	probably damaging	Het
Guf1	T	C	5: 69,566,386 (GRCm38)	I348T	probably damaging	Het
Htra4	T	A	8: 25,037,144 (GRCm38)	I212L	probably benign	Het
Itih5	G	A	2: 10,249,188 (GRCm38)	R750Q	probably benign	Het
Lgr6	C	T	1: 134,994,010 (GRCm38)	A199T	probably damaging	Het
Naip2	T	C	13: 100,161,854 (GRCm38)	E558G	probably benign	Het
Naip2	C	T	13: 100,161,860 (GRCm38)	G556D	probably benign	Het
Nsd1	T	C	13: 55,277,590 (GRCm38)	V1520A	probably benign	Het
Nuak1	C	T	10: 84,375,280 (GRCm38)	V315I	probably damaging	Het
Nup205	G	T	6: 35,236,892 (GRCm38)	G1740C	probably damaging	Het
Olfr398	G	C	11: 73,983,859 (GRCm38)	L250V	probably damaging	Het
Pclo	T	C	5: 14,676,686 (GRCm38)		probably benign	Het
Pik3r6	T	C	11: 68,536,101 (GRCm38)		probably benign	Het
Pikfyve	T	A	1: 65,253,397 (GRCm38)	F1336I	probably damaging	Het
Pla2r1	A	G	2: 60,514,947 (GRCm38)	I355T	possibly damaging	Het
Rgs22	A	T	15: 36,103,902 (GRCm38)		probably benign	Het
Sec63	T	A	10: 42,801,928 (GRCm38)	M312K	probably damaging	Het
Slc2a5	T	C	4: 150,142,830 (GRCm38)	I401T	probably benign	Het
Slc9a8	G	T	2: 167,434,867 (GRCm38)		probably benign	Het
Stab1	T	C	14: 31,145,249 (GRCm38)	E1718G	probably benign	Het
Terb1	A	T	8: 104,452,636 (GRCm38)	I640N	probably damaging	Het
Tmem217	A	G	17: 29,526,516 (GRCm38)	L80P	probably damaging	Het
Topbp1	C	T	9: 103,328,593 (GRCm38)	P810L	probably benign	Het
Ttbk2	G	A	2: 120,783,781 (GRCm38)	R151C	probably damaging	Het
Vmn2r88	T	G	14: 51,418,209 (GRCm38)	L626R	probably damaging	Het

Predicted Primers

PCR Primer
(F):5'- GACATTAGGCTTCGGTTGGCAGAG -3'
(R):5'- TATTTCCCATGCTGCACTGTGGGC -3'

Sequencing Primer
(F):5'- AGAGCCTCTGACCCTTGG -3'
(R):5'- CGTGGGTTACCACATGGC -3'

Posted On

2013-11-08