Incidental Mutation 'R0906:Gm4945'
ID 83341
Institutional Source Beutler Lab
Gene Symbol Gm4945
Ensembl Gene ENSMUSG00000062472
Gene Name predicted gene 4945
MMRRC Submission 039064-MU
Accession Numbers
Essential gene? Possibly non essential (E-score: 0.307) question?
Stock # R0906 (G1)
Quality Score 160
Status Validated
Chromosome 17
Chromosomal Location 47042587-47043039 bp(-) (GRCm38)
Type of Mutation exon
DNA Base Change (assembly) A to C at 47042870 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000075152
SMART Domains Protein: ENSMUSP00000074649
Gene: ENSMUSG00000062472

Pfam:Ribosomal_L29e 3 42 2.6e-29 PFAM
low complexity region 117 143 N/A INTRINSIC
Coding Region Coverage
  • 1x: 99.5%
  • 3x: 99.0%
  • 10x: 97.8%
  • 20x: 96.3%
Validation Efficiency 100% (33/33)
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
AA986860 T A 1: 130,737,693 (GRCm38) probably benign Het
Atp7b T C 8: 22,027,826 (GRCm38) H332R probably benign Het
Bace2 C T 16: 97,356,941 (GRCm38) P47L possibly damaging Het
Cyp2c39 A G 19: 39,510,871 (GRCm38) M1V probably null Het
Dcbld2 A G 16: 58,455,247 (GRCm38) E442G probably damaging Het
Gm14496 A G 2: 182,000,515 (GRCm38) T660A probably damaging Het
Gm5065 T C 7: 5,359,829 (GRCm38) I153T probably damaging Het
Gm6729 T C 10: 86,540,592 (GRCm38) noncoding transcript Het
Golga1 G A 2: 39,047,643 (GRCm38) R204W probably damaging Het
Guf1 T C 5: 69,566,386 (GRCm38) I348T probably damaging Het
Htra4 T A 8: 25,037,144 (GRCm38) I212L probably benign Het
Itih5 G A 2: 10,249,188 (GRCm38) R750Q probably benign Het
Lgr6 C T 1: 134,994,010 (GRCm38) A199T probably damaging Het
Naip2 T C 13: 100,161,854 (GRCm38) E558G probably benign Het
Naip2 C T 13: 100,161,860 (GRCm38) G556D probably benign Het
Nsd1 T C 13: 55,277,590 (GRCm38) V1520A probably benign Het
Nuak1 C T 10: 84,375,280 (GRCm38) V315I probably damaging Het
Nup205 G T 6: 35,236,892 (GRCm38) G1740C probably damaging Het
Olfr398 G C 11: 73,983,859 (GRCm38) L250V probably damaging Het
Pclo T C 5: 14,676,686 (GRCm38) probably benign Het
Pik3r6 T C 11: 68,536,101 (GRCm38) probably benign Het
Pikfyve T A 1: 65,253,397 (GRCm38) F1336I probably damaging Het
Pla2r1 A G 2: 60,514,947 (GRCm38) I355T possibly damaging Het
Rgs22 A T 15: 36,103,902 (GRCm38) probably benign Het
Sec63 T A 10: 42,801,928 (GRCm38) M312K probably damaging Het
Slc2a5 T C 4: 150,142,830 (GRCm38) I401T probably benign Het
Slc9a8 G T 2: 167,434,867 (GRCm38) probably benign Het
Stab1 T C 14: 31,145,249 (GRCm38) E1718G probably benign Het
Terb1 A T 8: 104,452,636 (GRCm38) I640N probably damaging Het
Tmem217 A G 17: 29,526,516 (GRCm38) L80P probably damaging Het
Topbp1 C T 9: 103,328,593 (GRCm38) P810L probably benign Het
Ttbk2 G A 2: 120,783,781 (GRCm38) R151C probably damaging Het
Vmn2r88 T G 14: 51,418,209 (GRCm38) L626R probably damaging Het
Predicted Primers PCR Primer

Sequencing Primer
Posted On 2013-11-08