Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01448:Celsr2'

84528

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Celsr2

Ensembl Gene

ENSMUSG00000068740

Gene Name

cadherin, EGF LAG seven-pass G-type receptor 2

Synonyms

mfmi1, EGFL2, flamingo

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01448

Quality Score

Status

Chromosome

Chromosomal Location

108390851-108415552 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 108393239 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 2835 (L2835P)

Ref Sequence

ENSEMBL: ENSMUSP00000088046 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090558]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000090558
AA Change: L2835P

PolyPhen 2 Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000088046
Gene: ENSMUSG00000068740
AA Change: L2835P

Domain	Start	End	E-Value	Type
signal peptide	1	31	N/A	INTRINSIC
low complexity region	35	53	N/A	INTRINSIC
CA	203	287	1.36e-26	SMART
CA	311	397	1.33e-29	SMART
CA	421	503	2.59e-27	SMART
CA	527	608	3.33e-30	SMART
CA	632	710	5.18e-18	SMART
CA	734	813	1.08e-29	SMART
CA	837	919	8.08e-29	SMART
low complexity region	920	932	N/A	INTRINSIC
CA	943	1021	4.3e-24	SMART
CA	1049	1125	1.87e-1	SMART
low complexity region	1188	1198	N/A	INTRINSIC
EGF	1231	1286	1.81e-3	SMART
EGF_CA	1288	1324	2.24e-8	SMART
EGF	1331	1366	6.65e-2	SMART
LamG	1387	1554	8.4e-30	SMART
EGF	1577	1610	8e-5	SMART
LamG	1636	1770	1.56e-24	SMART
EGF	1796	1829	2.35e-2	SMART
EGF	1831	1867	3.88e-3	SMART
TNFR	1908	1943	1.35e-1	SMART
EGF_Lam	1924	1969	9.54e-12	SMART
HormR	1972	2034	1.57e-20	SMART
Pfam:GAIN	2046	2289	3e-62	PFAM
GPS	2315	2368	1.86e-25	SMART
Pfam:7tm_2	2373	2605	1.1e-48	PFAM
low complexity region	2715	2733	N/A	INTRINSIC
low complexity region	2857	2873	N/A	INTRINSIC
low complexity region	2874	2881	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126349

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126935

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000130941

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000133216

Predicted Effect

unknown
Transcript: ENSMUST00000147251
AA Change: L823P

SMART Domains

Protein: ENSMUSP00000122329
Gene: ENSMUSG00000068740
AA Change: L823P

Domain	Start	End	E-Value	Type
Pfam:GAIN	35	278	5.1e-63	PFAM
GPS	304	357	1.86e-25	SMART
Pfam:7tm_2	362	594	2e-49	PFAM
low complexity region	704	722	N/A	INTRINSIC
low complexity region	846	862	N/A	INTRINSIC
low complexity region	863	870	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for disruptions in this allele have mild to moderately dilated lateral ventricles in the brain but are otherwise normal. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Targeted, knock-out(1) Targeted, other(3)

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700020A23Rik	A	T	2: 130,405,847 (GRCm38)	E75D	possibly damaging	Het
1700084J12Rik	A	G	15: 33,405,633 (GRCm38)		probably benign	Het
2610303G11Rik	T	A	9: 98,186,709 (GRCm38)		noncoding transcript	Het
4931414P19Rik	T	C	14: 54,585,960 (GRCm38)	D320G	possibly damaging	Het
Adamts6	G	A	13: 104,297,164 (GRCm38)	E34K	probably damaging	Het
Alms1	T	A	6: 85,677,899 (GRCm38)	N3142K	possibly damaging	Het
Anapc7	G	A	5: 122,428,213 (GRCm38)	A62T	probably damaging	Het
Atp8b3	G	A	10: 80,520,422 (GRCm38)	P1152L	probably benign	Het
Cc2d2a	C	T	5: 43,684,185 (GRCm38)	T181I	possibly damaging	Het
Ctns	A	T	11: 73,188,722 (GRCm38)	V99D	possibly damaging	Het
Dchs1	T	C	7: 105,771,927 (GRCm38)	R429G	probably damaging	Het
Ddx11	T	C	17: 66,134,137 (GRCm38)	V218A	probably damaging	Het
Eftud2	G	A	11: 102,865,563 (GRCm38)		probably benign	Het
Erich1	G	T	8: 14,078,853 (GRCm38)	T29N	possibly damaging	Het
Exosc8	T	C	3: 54,729,265 (GRCm38)	E215G	probably damaging	Het
Fam184a	G	T	10: 53,698,949 (GRCm38)	A188E	probably benign	Het
Fign	A	G	2: 63,979,688 (GRCm38)	S413P	probably damaging	Het
Fkbp6	A	G	5: 135,349,696 (GRCm38)	S33P	probably damaging	Het
Glb1	A	G	9: 114,450,677 (GRCm38)		probably benign	Het
H2-Q1	T	C	17: 35,323,461 (GRCm38)		probably benign	Het
Helz2	T	C	2: 181,233,977 (GRCm38)	T1575A	probably damaging	Het
Il18r1	A	G	1: 40,474,730 (GRCm38)	E32G	probably damaging	Het
Ints5	C	T	19: 8,895,487 (GRCm38)	P270L	possibly damaging	Het
Itga7	G	T	10: 128,949,468 (GRCm38)	E847*	probably null	Het
Kcns3	A	C	12: 11,091,643 (GRCm38)	S352A	possibly damaging	Het
Kiz	A	G	2: 146,863,801 (GRCm38)	K94E	probably benign	Het
Lin7b	C	T	7: 45,369,200 (GRCm38)	V12M	probably damaging	Het
Myo18b	A	T	5: 112,811,704 (GRCm38)	I1409N	probably damaging	Het
Myo5b	A	G	18: 74,644,090 (GRCm38)	H407R	probably damaging	Het
Nelfa	T	C	5: 33,898,802 (GRCm38)	T506A	probably damaging	Het
Or10p21	A	G	10: 129,011,860 (GRCm38)	T192A	probably damaging	Het
Or4d5	A	T	9: 40,101,082 (GRCm38)	M136K	probably damaging	Het
Or5p72	T	A	7: 108,423,028 (GRCm38)	Y152*	probably null	Het
Or6c69	A	G	10: 129,912,245 (GRCm38)	I11T	possibly damaging	Het
Pclo	A	C	5: 14,676,394 (GRCm38)		probably benign	Het
Pes1	G	A	11: 3,977,979 (GRCm38)	E544K	possibly damaging	Het
Rabgap1l	A	G	1: 160,740,745 (GRCm38)		probably benign	Het
Rapgef2	T	C	3: 79,068,937 (GRCm38)	M1521V	probably benign	Het
Rapgef2	C	T	3: 79,103,962 (GRCm38)		probably null	Het
Reln	A	G	5: 22,040,405 (GRCm38)	V735A	probably benign	Het
Slc2a4	A	G	11: 69,945,076 (GRCm38)	S316P	possibly damaging	Het
Smarce1	C	T	11: 99,210,187 (GRCm38)	G373E	possibly damaging	Het
Spata31d1a	T	A	13: 59,701,559 (GRCm38)	R918S	probably benign	Het
St3gal4	T	C	9: 35,052,331 (GRCm38)	K227R	probably benign	Het
Stra6l	T	A	4: 45,864,864 (GRCm38)		probably null	Het
Stxbp5l	T	C	16: 37,215,979 (GRCm38)	I425V	probably damaging	Het
Tcaf2	T	C	6: 42,630,328 (GRCm38)	T231A	probably benign	Het
Tiparp	G	T	3: 65,552,609 (GRCm38)	G442*	probably null	Het
Tnks	A	G	8: 34,839,982 (GRCm38)	Y1138H	probably damaging	Het
Vezt	T	A	10: 93,996,857 (GRCm38)	I231F	probably damaging	Het
Vmn2r4	A	T	3: 64,406,395 (GRCm38)	N388K	probably damaging	Het
Zbed3	A	G	13: 95,336,634 (GRCm38)	K189E	possibly damaging	Het
Zfp512b	T	C	2: 181,587,785 (GRCm38)	T625A	possibly damaging	Het
Zfp827	A	T	8: 79,060,733 (GRCm38)	Q176L	possibly damaging	Het

Other mutations in Celsr2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00898:Celsr2	APN	3	108,413,879 (GRCm38)	missense	possibly damaging	0.49
IGL01020:Celsr2	APN	3	108,403,270 (GRCm38)	missense	probably damaging	0.99
IGL01420:Celsr2	APN	3	108,393,763 (GRCm38)	missense	probably benign	0.13
IGL01559:Celsr2	APN	3	108,406,867 (GRCm38)	missense	possibly damaging	0.75
IGL01674:Celsr2	APN	3	108,414,843 (GRCm38)	missense	probably damaging	1.00
IGL01863:Celsr2	APN	3	108,394,022 (GRCm38)	missense	probably benign	0.00
IGL02309:Celsr2	APN	3	108,396,011 (GRCm38)	missense	probably damaging	1.00
IGL02325:Celsr2	APN	3	108,412,871 (GRCm38)	missense	probably damaging	1.00
IGL02409:Celsr2	APN	3	108,413,955 (GRCm38)	missense	probably damaging	1.00
IGL02514:Celsr2	APN	3	108,397,510 (GRCm38)	missense	probably benign	0.01
IGL02812:Celsr2	APN	3	108,414,113 (GRCm38)	missense	probably benign	0.25
IGL02894:Celsr2	APN	3	108,395,210 (GRCm38)	missense	probably damaging	1.00
IGL03281:Celsr2	APN	3	108,412,940 (GRCm38)	missense	probably damaging	1.00
barrow	UTSW	3	108,394,965 (GRCm38)	missense	possibly damaging	0.92
goldeneye	UTSW	3	108,394,919 (GRCm38)	missense	probably damaging	1.00
1mM(1):Celsr2	UTSW	3	108,400,838 (GRCm38)	missense	probably benign	0.01
ANU74:Celsr2	UTSW	3	108,412,499 (GRCm38)	missense	probably damaging	1.00
IGL02799:Celsr2	UTSW	3	108,414,062 (GRCm38)	missense	probably damaging	1.00
R0011:Celsr2	UTSW	3	108,413,402 (GRCm38)	missense	probably benign	0.19
R0031:Celsr2	UTSW	3	108,413,063 (GRCm38)	missense	probably damaging	1.00
R0049:Celsr2	UTSW	3	108,397,254 (GRCm38)	missense	probably benign	0.12
R0049:Celsr2	UTSW	3	108,397,254 (GRCm38)	missense	probably benign	0.12
R0090:Celsr2	UTSW	3	108,393,327 (GRCm38)	splice site	probably benign
R0140:Celsr2	UTSW	3	108,397,933 (GRCm38)	missense	probably benign	0.00
R0524:Celsr2	UTSW	3	108,401,587 (GRCm38)	missense	probably damaging	1.00
R0607:Celsr2	UTSW	3	108,403,895 (GRCm38)	critical splice donor site	probably null
R0662:Celsr2	UTSW	3	108,398,520 (GRCm38)	missense	probably damaging	0.99
R0690:Celsr2	UTSW	3	108,414,977 (GRCm38)	missense	probably damaging	1.00
R0691:Celsr2	UTSW	3	108,412,623 (GRCm38)	missense	probably damaging	1.00
R0710:Celsr2	UTSW	3	108,412,712 (GRCm38)	missense	probably benign	0.42
R0730:Celsr2	UTSW	3	108,398,606 (GRCm38)	missense	probably damaging	1.00
R0815:Celsr2	UTSW	3	108,401,301 (GRCm38)	missense	possibly damaging	0.56
R0848:Celsr2	UTSW	3	108,414,338 (GRCm38)	missense	probably benign
R0989:Celsr2	UTSW	3	108,403,272 (GRCm38)	missense	probably benign	0.00
R1185:Celsr2	UTSW	3	108,399,709 (GRCm38)	missense	possibly damaging	0.95
R1185:Celsr2	UTSW	3	108,399,709 (GRCm38)	missense	possibly damaging	0.95
R1185:Celsr2	UTSW	3	108,399,709 (GRCm38)	missense	possibly damaging	0.95
R1469:Celsr2	UTSW	3	108,414,108 (GRCm38)	missense	probably damaging	1.00
R1469:Celsr2	UTSW	3	108,414,108 (GRCm38)	missense	probably damaging	1.00
R1474:Celsr2	UTSW	3	108,393,739 (GRCm38)	missense	possibly damaging	0.91
R1608:Celsr2	UTSW	3	108,402,483 (GRCm38)	missense	probably damaging	1.00
R1653:Celsr2	UTSW	3	108,413,520 (GRCm38)	missense	possibly damaging	0.52
R1659:Celsr2	UTSW	3	108,414,095 (GRCm38)	missense	probably benign
R1689:Celsr2	UTSW	3	108,407,304 (GRCm38)	missense	possibly damaging	0.63
R1848:Celsr2	UTSW	3	108,401,310 (GRCm38)	missense	probably benign	0.35
R1859:Celsr2	UTSW	3	108,396,630 (GRCm38)	missense	probably damaging	1.00
R1918:Celsr2	UTSW	3	108,398,650 (GRCm38)	missense	probably benign	0.05
R1974:Celsr2	UTSW	3	108,414,214 (GRCm38)	missense	probably damaging	1.00
R2042:Celsr2	UTSW	3	108,402,495 (GRCm38)	missense	probably damaging	0.98
R2167:Celsr2	UTSW	3	108,413,193 (GRCm38)	missense	probably damaging	0.96
R2333:Celsr2	UTSW	3	108,398,605 (GRCm38)	missense	probably benign	0.16
R2434:Celsr2	UTSW	3	108,404,479 (GRCm38)	missense	probably damaging	1.00
R2504:Celsr2	UTSW	3	108,413,591 (GRCm38)	missense	probably benign	0.11
R3420:Celsr2	UTSW	3	108,414,416 (GRCm38)	missense	probably benign	0.03
R3712:Celsr2	UTSW	3	108,400,839 (GRCm38)	missense	probably benign
R3723:Celsr2	UTSW	3	108,397,415 (GRCm38)	splice site	probably benign
R3809:Celsr2	UTSW	3	108,403,239 (GRCm38)	missense	possibly damaging	0.67
R4018:Celsr2	UTSW	3	108,394,965 (GRCm38)	missense	possibly damaging	0.92
R4126:Celsr2	UTSW	3	108,402,097 (GRCm38)	missense	possibly damaging	0.71
R4177:Celsr2	UTSW	3	108,413,978 (GRCm38)	missense	probably damaging	0.96
R4232:Celsr2	UTSW	3	108,413,772 (GRCm38)	missense	probably benign	0.02
R4293:Celsr2	UTSW	3	108,393,677 (GRCm38)	missense	probably benign	0.01
R4458:Celsr2	UTSW	3	108,394,997 (GRCm38)	missense	probably damaging	0.98
R4621:Celsr2	UTSW	3	108,395,216 (GRCm38)	missense	possibly damaging	0.86
R4645:Celsr2	UTSW	3	108,395,969 (GRCm38)	missense	probably damaging	1.00
R4700:Celsr2	UTSW	3	108,397,231 (GRCm38)	missense	probably benign	0.24
R4732:Celsr2	UTSW	3	108,398,952 (GRCm38)	missense	probably damaging	0.99
R4733:Celsr2	UTSW	3	108,398,952 (GRCm38)	missense	probably damaging	0.99
R4901:Celsr2	UTSW	3	108,406,987 (GRCm38)	missense	possibly damaging	0.81
R4932:Celsr2	UTSW	3	108,402,758 (GRCm38)	missense	probably damaging	1.00
R4989:Celsr2	UTSW	3	108,412,629 (GRCm38)	missense	possibly damaging	0.62
R5052:Celsr2	UTSW	3	108,412,358 (GRCm38)	missense	probably damaging	1.00
R5093:Celsr2	UTSW	3	108,413,373 (GRCm38)	missense	possibly damaging	0.66
R5114:Celsr2	UTSW	3	108,393,996 (GRCm38)	missense	probably benign	0.05
R5120:Celsr2	UTSW	3	108,393,120 (GRCm38)	missense	probably benign	0.02
R5135:Celsr2	UTSW	3	108,398,659 (GRCm38)	missense	probably damaging	1.00
R5247:Celsr2	UTSW	3	108,397,630 (GRCm38)	missense	probably benign	0.34
R5381:Celsr2	UTSW	3	108,402,757 (GRCm38)	missense	probably damaging	1.00
R5412:Celsr2	UTSW	3	108,399,995 (GRCm38)	missense	probably damaging	1.00
R5445:Celsr2	UTSW	3	108,392,658 (GRCm38)	missense	probably benign	0.01
R5528:Celsr2	UTSW	3	108,413,294 (GRCm38)	missense	probably damaging	1.00
R5598:Celsr2	UTSW	3	108,402,803 (GRCm38)	missense	possibly damaging	0.82
R5652:Celsr2	UTSW	3	108,396,735 (GRCm38)	missense	probably null	0.49
R5697:Celsr2	UTSW	3	108,403,921 (GRCm38)	nonsense	probably null
R5718:Celsr2	UTSW	3	108,393,358 (GRCm38)	missense	probably benign
R5869:Celsr2	UTSW	3	108,413,909 (GRCm38)	missense	probably damaging	1.00
R5876:Celsr2	UTSW	3	108,413,943 (GRCm38)	missense	probably damaging	0.96
R6021:Celsr2	UTSW	3	108,401,245 (GRCm38)	missense	probably benign
R6054:Celsr2	UTSW	3	108,406,963 (GRCm38)	missense	possibly damaging	0.95
R6244:Celsr2	UTSW	3	108,393,128 (GRCm38)	missense	probably damaging	0.96
R6313:Celsr2	UTSW	3	108,401,214 (GRCm38)	missense	probably damaging	0.99
R6322:Celsr2	UTSW	3	108,412,574 (GRCm38)	missense	probably damaging	1.00
R6555:Celsr2	UTSW	3	108,394,919 (GRCm38)	missense	probably damaging	1.00
R6682:Celsr2	UTSW	3	108,400,501 (GRCm38)	critical splice donor site	probably null
R7062:Celsr2	UTSW	3	108,402,510 (GRCm38)	missense	possibly damaging	0.95
R7110:Celsr2	UTSW	3	108,397,865 (GRCm38)	missense	probably damaging	1.00
R7139:Celsr2	UTSW	3	108,415,359 (GRCm38)	missense	unknown
R7326:Celsr2	UTSW	3	108,394,995 (GRCm38)	missense	possibly damaging	0.85
R7425:Celsr2	UTSW	3	108,402,457 (GRCm38)	missense	probably damaging	1.00
R7452:Celsr2	UTSW	3	108,413,090 (GRCm38)	missense	possibly damaging	0.95
R7461:Celsr2	UTSW	3	108,395,640 (GRCm38)	missense	probably damaging	1.00
R7502:Celsr2	UTSW	3	108,398,902 (GRCm38)	missense	probably benign	0.00
R7613:Celsr2	UTSW	3	108,395,640 (GRCm38)	missense	probably damaging	1.00
R7644:Celsr2	UTSW	3	108,413,490 (GRCm38)	missense	probably damaging	0.99
R7666:Celsr2	UTSW	3	108,398,588 (GRCm38)	missense	probably benign
R7687:Celsr2	UTSW	3	108,397,769 (GRCm38)	missense	probably benign	0.27
R7695:Celsr2	UTSW	3	108,402,753 (GRCm38)	missense	probably damaging	1.00
R8002:Celsr2	UTSW	3	108,403,969 (GRCm38)	missense	probably damaging	1.00
R8052:Celsr2	UTSW	3	108,412,655 (GRCm38)	missense	probably damaging	1.00
R8283:Celsr2	UTSW	3	108,396,455 (GRCm38)	missense	probably damaging	1.00
R8356:Celsr2	UTSW	3	108,413,531 (GRCm38)	missense	possibly damaging	0.90
R8381:Celsr2	UTSW	3	108,395,636 (GRCm38)	missense	probably damaging	1.00
R8427:Celsr2	UTSW	3	108,392,633 (GRCm38)	makesense	probably null
R8435:Celsr2	UTSW	3	108,414,399 (GRCm38)	missense	probably benign
R8438:Celsr2	UTSW	3	108,393,823 (GRCm38)	missense	probably damaging	1.00
R8458:Celsr2	UTSW	3	108,398,902 (GRCm38)	missense	probably benign	0.00
R8460:Celsr2	UTSW	3	108,396,777 (GRCm38)	missense	possibly damaging	0.84
R8462:Celsr2	UTSW	3	108,412,851 (GRCm38)	nonsense	probably null
R8479:Celsr2	UTSW	3	108,398,902 (GRCm38)	missense	probably benign	0.00
R8480:Celsr2	UTSW	3	108,398,902 (GRCm38)	missense	probably benign	0.00
R8512:Celsr2	UTSW	3	108,413,838 (GRCm38)	missense	probably damaging	1.00
R8694:Celsr2	UTSW	3	108,406,860 (GRCm38)	missense	probably damaging	1.00
R8772:Celsr2	UTSW	3	108,397,073 (GRCm38)	missense	possibly damaging	0.84
R8843:Celsr2	UTSW	3	108,396,127 (GRCm38)	splice site	probably benign
R8888:Celsr2	UTSW	3	108,413,564 (GRCm38)	missense	possibly damaging	0.95
R8895:Celsr2	UTSW	3	108,413,564 (GRCm38)	missense	possibly damaging	0.95
R8917:Celsr2	UTSW	3	108,396,566 (GRCm38)	missense	probably benign	0.00
R9119:Celsr2	UTSW	3	108,401,972 (GRCm38)	missense	possibly damaging	0.90
R9169:Celsr2	UTSW	3	108,402,546 (GRCm38)	missense	probably benign	0.04
R9209:Celsr2	UTSW	3	108,414,033 (GRCm38)	missense	probably benign	0.02
R9342:Celsr2	UTSW	3	108,413,126 (GRCm38)	missense	probably damaging	1.00
R9416:Celsr2	UTSW	3	108,414,768 (GRCm38)	missense	probably damaging	0.96
R9493:Celsr2	UTSW	3	108,393,758 (GRCm38)	missense	probably damaging	1.00
R9564:Celsr2	UTSW	3	108,414,518 (GRCm38)	missense	probably damaging	1.00
R9598:Celsr2	UTSW	3	108,415,262 (GRCm38)	missense	possibly damaging	0.72
R9629:Celsr2	UTSW	3	108,401,599 (GRCm38)	missense	probably damaging	1.00
R9691:Celsr2	UTSW	3	108,394,235 (GRCm38)	missense	probably damaging	1.00
X0020:Celsr2	UTSW	3	108,396,110 (GRCm38)	missense	probably damaging	1.00
X0050:Celsr2	UTSW	3	108,401,272 (GRCm38)	missense	probably benign	0.09
Z1088:Celsr2	UTSW	3	108,414,117 (GRCm38)	missense	probably damaging	1.00
Z1176:Celsr2	UTSW	3	108,412,341 (GRCm38)	missense	probably benign	0.07
Z1176:Celsr2	UTSW	3	108,393,131 (GRCm38)	missense	probably benign	0.10
Z1177:Celsr2	UTSW	3	108,413,571 (GRCm38)	missense	probably benign	0.32
Z1177:Celsr2	UTSW	3	108,412,220 (GRCm38)	missense	probably damaging	1.00
Z1191:Celsr2	UTSW	3	108,414,549 (GRCm38)	missense	possibly damaging	0.68

Posted On

2013-11-11