Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01448:Stra6l'

84542

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Stra6l

Ensembl Gene

ENSMUSG00000028327

Gene Name

STRA6-like

Synonyms

Rbpr2, 1300002K09Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01448

Quality Score

Status

Chromosome

Chromosomal Location

45848664-45887008 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to A at 45864864 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000103412 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030011] [ENSMUST00000030011] [ENSMUST00000107782] [ENSMUST00000107783]

AlphaFold

Q9DBN1

Predicted Effect

probably null
Transcript: ENSMUST00000030011

SMART Domains

Protein: ENSMUSP00000030011
Gene: ENSMUSG00000028327

Domain	Start	End	E-Value	Type
Pfam:RBP_receptor	13	602	8.7e-228	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000030011

SMART Domains

Protein: ENSMUSP00000030011
Gene: ENSMUSG00000028327

Domain	Start	End	E-Value	Type
Pfam:RBP_receptor	13	602	8.7e-228	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000107782

SMART Domains

Protein: ENSMUSP00000103411
Gene: ENSMUSG00000028327

Domain	Start	End	E-Value	Type
Pfam:RBP_receptor	1	512	2.8e-221	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000107783

SMART Domains

Protein: ENSMUSP00000103412
Gene: ENSMUSG00000028327

Domain	Start	End	E-Value	Type
Pfam:RBP_receptor	12	603	1e-254	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000128947

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700020A23Rik	A	T	2: 130,405,847 (GRCm38)	E75D	possibly damaging	Het
1700084J12Rik	A	G	15: 33,405,633 (GRCm38)		probably benign	Het
2610303G11Rik	T	A	9: 98,186,709 (GRCm38)		noncoding transcript	Het
4931414P19Rik	T	C	14: 54,585,960 (GRCm38)	D320G	possibly damaging	Het
Adamts6	G	A	13: 104,297,164 (GRCm38)	E34K	probably damaging	Het
Alms1	T	A	6: 85,677,899 (GRCm38)	N3142K	possibly damaging	Het
Anapc7	G	A	5: 122,428,213 (GRCm38)	A62T	probably damaging	Het
Atp8b3	G	A	10: 80,520,422 (GRCm38)	P1152L	probably benign	Het
Cc2d2a	C	T	5: 43,684,185 (GRCm38)	T181I	possibly damaging	Het
Celsr2	A	G	3: 108,393,239 (GRCm38)	L2835P	probably damaging	Het
Ctns	A	T	11: 73,188,722 (GRCm38)	V99D	possibly damaging	Het
Dchs1	T	C	7: 105,771,927 (GRCm38)	R429G	probably damaging	Het
Ddx11	T	C	17: 66,134,137 (GRCm38)	V218A	probably damaging	Het
Eftud2	G	A	11: 102,865,563 (GRCm38)		probably benign	Het
Erich1	G	T	8: 14,078,853 (GRCm38)	T29N	possibly damaging	Het
Exosc8	T	C	3: 54,729,265 (GRCm38)	E215G	probably damaging	Het
Fam184a	G	T	10: 53,698,949 (GRCm38)	A188E	probably benign	Het
Fign	A	G	2: 63,979,688 (GRCm38)	S413P	probably damaging	Het
Fkbp6	A	G	5: 135,349,696 (GRCm38)	S33P	probably damaging	Het
Glb1	A	G	9: 114,450,677 (GRCm38)		probably benign	Het
H2-Q1	T	C	17: 35,323,461 (GRCm38)		probably benign	Het
Helz2	T	C	2: 181,233,977 (GRCm38)	T1575A	probably damaging	Het
Il18r1	A	G	1: 40,474,730 (GRCm38)	E32G	probably damaging	Het
Ints5	C	T	19: 8,895,487 (GRCm38)	P270L	possibly damaging	Het
Itga7	G	T	10: 128,949,468 (GRCm38)	E847*	probably null	Het
Kcns3	A	C	12: 11,091,643 (GRCm38)	S352A	possibly damaging	Het
Kiz	A	G	2: 146,863,801 (GRCm38)	K94E	probably benign	Het
Lin7b	C	T	7: 45,369,200 (GRCm38)	V12M	probably damaging	Het
Myo18b	A	T	5: 112,811,704 (GRCm38)	I1409N	probably damaging	Het
Myo5b	A	G	18: 74,644,090 (GRCm38)	H407R	probably damaging	Het
Nelfa	T	C	5: 33,898,802 (GRCm38)	T506A	probably damaging	Het
Olfr497	T	A	7: 108,423,028 (GRCm38)	Y152*	probably null	Het
Olfr763	A	G	10: 129,011,860 (GRCm38)	T192A	probably damaging	Het
Olfr816	A	G	10: 129,912,245 (GRCm38)	I11T	possibly damaging	Het
Olfr984	A	T	9: 40,101,082 (GRCm38)	M136K	probably damaging	Het
Pclo	A	C	5: 14,676,394 (GRCm38)		probably benign	Het
Pes1	G	A	11: 3,977,979 (GRCm38)	E544K	possibly damaging	Het
Rabgap1l	A	G	1: 160,740,745 (GRCm38)		probably benign	Het
Rapgef2	T	C	3: 79,068,937 (GRCm38)	M1521V	probably benign	Het
Rapgef2	C	T	3: 79,103,962 (GRCm38)		probably null	Het
Reln	A	G	5: 22,040,405 (GRCm38)	V735A	probably benign	Het
Slc2a4	A	G	11: 69,945,076 (GRCm38)	S316P	possibly damaging	Het
Smarce1	C	T	11: 99,210,187 (GRCm38)	G373E	possibly damaging	Het
Spata31d1a	T	A	13: 59,701,559 (GRCm38)	R918S	probably benign	Het
St3gal4	T	C	9: 35,052,331 (GRCm38)	K227R	probably benign	Het
Stxbp5l	T	C	16: 37,215,979 (GRCm38)	I425V	probably damaging	Het
Tcaf2	T	C	6: 42,630,328 (GRCm38)	T231A	probably benign	Het
Tiparp	G	T	3: 65,552,609 (GRCm38)	G442*	probably null	Het
Tnks	A	G	8: 34,839,982 (GRCm38)	Y1138H	probably damaging	Het
Vezt	T	A	10: 93,996,857 (GRCm38)	I231F	probably damaging	Het
Vmn2r4	A	T	3: 64,406,395 (GRCm38)	N388K	probably damaging	Het
Zbed3	A	G	13: 95,336,634 (GRCm38)	K189E	possibly damaging	Het
Zfp512b	T	C	2: 181,587,785 (GRCm38)	T625A	possibly damaging	Het
Zfp827	A	T	8: 79,060,733 (GRCm38)	Q176L	possibly damaging	Het

Other mutations in Stra6l

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02343:Stra6l	APN	4	45,869,588 (GRCm38)	missense	probably damaging	0.99
IGL02710:Stra6l	APN	4	45,882,728 (GRCm38)	missense	possibly damaging	0.72
IGL02880:Stra6l	APN	4	45,885,278 (GRCm38)	missense	possibly damaging	0.70
IGL03034:Stra6l	APN	4	45,885,392 (GRCm38)	missense	probably benign	0.41
IGL03163:Stra6l	APN	4	45,881,455 (GRCm38)	missense	probably benign	0.03
IGL03355:Stra6l	APN	4	45,873,689 (GRCm38)	missense	probably benign	0.16
K2124:Stra6l	UTSW	4	45,870,770 (GRCm38)	splice site	probably benign
R0800:Stra6l	UTSW	4	45,882,797 (GRCm38)	missense	probably benign	0.29
R1171:Stra6l	UTSW	4	45,864,982 (GRCm38)	missense	probably benign
R1931:Stra6l	UTSW	4	45,882,698 (GRCm38)	nonsense	probably null
R1982:Stra6l	UTSW	4	45,867,237 (GRCm38)	nonsense	probably null
R2331:Stra6l	UTSW	4	45,858,224 (GRCm38)	critical splice donor site	probably null
R4691:Stra6l	UTSW	4	45,882,851 (GRCm38)	missense	probably benign	0.39
R4846:Stra6l	UTSW	4	45,873,682 (GRCm38)	missense	possibly damaging	0.76
R5175:Stra6l	UTSW	4	45,870,860 (GRCm38)	missense	probably benign	0.01
R5633:Stra6l	UTSW	4	45,881,455 (GRCm38)	missense	probably benign	0.00
R6212:Stra6l	UTSW	4	45,884,664 (GRCm38)	missense	probably benign
R6517:Stra6l	UTSW	4	45,879,473 (GRCm38)	missense	probably benign
R6534:Stra6l	UTSW	4	45,860,041 (GRCm38)	splice site	probably null
R6584:Stra6l	UTSW	4	45,869,635 (GRCm38)	splice site	probably null
R7763:Stra6l	UTSW	4	45,869,570 (GRCm38)	nonsense	probably null
R8400:Stra6l	UTSW	4	45,864,905 (GRCm38)	missense	probably damaging	1.00
R8511:Stra6l	UTSW	4	45,885,347 (GRCm38)	missense	probably benign	0.00
R9007:Stra6l	UTSW	4	45,864,910 (GRCm38)	missense	possibly damaging	0.81
R9313:Stra6l	UTSW	4	45,881,454 (GRCm38)	missense	probably benign
R9379:Stra6l	UTSW	4	45,849,093 (GRCm38)	missense	probably benign
R9400:Stra6l	UTSW	4	45,885,293 (GRCm38)	missense	probably damaging	1.00
R9764:Stra6l	UTSW	4	45,884,602 (GRCm38)	missense	probably damaging	0.98

Posted On

2013-11-11