Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01457:Vmn2r111'

84805

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r111

Ensembl Gene

ENSMUSG00000095093

Gene Name

vomeronasal 2, receptor 111

Synonyms

EG210876

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.100) question?

Stock #

IGL01457

Quality Score

Status

Chromosome

Chromosomal Location

22547941-22573273 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to A at 22571985 bp

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Stop codon at position 111 (E111*)

Ref Sequence

ENSEMBL: ENSMUSP00000090148 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092491]

Predicted Effect

probably null
Transcript: ENSMUST00000092491
AA Change: E111*

SMART Domains

Protein: ENSMUSP00000090148
Gene: ENSMUSG00000095093
AA Change: E111*

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	2.5e-29	PFAM
Pfam:NCD3G	512	565	1.1e-20	PFAM
Pfam:7tm_3	595	833	5.6e-54	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3425401B19Rik	T	A	14: 32,660,951	Y1019F	probably benign	Het
4930455H04Rik	T	G	3: 116,968,551		probably benign	Het
4930548H24Rik	A	T	5: 31,487,427	I175L	probably benign	Het
4932415D10Rik	C	A	10: 82,284,734	K4147N	probably damaging	Het
9830107B12Rik	A	T	17: 48,128,583		probably benign	Het
Abcc8	A	G	7: 46,135,493	V737A	possibly damaging	Het
Adamts20	T	A	15: 94,331,448	Y930F	probably damaging	Het
Alkbh8	T	A	9: 3,369,825	F365I	probably damaging	Het
App	G	A	16: 85,103,239	H108Y	probably damaging	Het
Bfsp1	T	C	2: 143,827,644		probably benign	Het
Cabin1	T	C	10: 75,742,429	N478S	probably damaging	Het
Camsap3	G	A	8: 3,604,795	V796I	probably damaging	Het
Carns1	A	T	19: 4,166,499		probably null	Het
Clca1	C	T	3: 145,007,778	M697I	probably benign	Het
Cltc	C	T	11: 86,702,248	M1600I	probably benign	Het
Cnot1	T	A	8: 95,741,009	N1499Y	probably damaging	Het
Crebbp	T	A	16: 4,124,768	I196L	probably damaging	Het
Drc3	C	A	11: 60,358,649		probably benign	Het
Fam161a	T	A	11: 23,020,702	Y234*	probably null	Het
Il1r1	C	A	1: 40,313,170	P500Q	probably damaging	Het
Katnal1	G	T	5: 148,893,797		probably benign	Het
Klhdc2	A	G	12: 69,297,053	N20S	probably benign	Het
Kmt2e	A	T	5: 23,502,019	T1527S	possibly damaging	Het
Magi1	C	T	6: 93,747,224	G270D	probably damaging	Het
Mdn1	T	A	4: 32,715,922	S2035T	possibly damaging	Het
Mki67	A	T	7: 135,699,546	M1253K	probably benign	Het
Myh7	T	C	14: 54,988,879	M435V	possibly damaging	Het
Myh8	A	G	11: 67,292,679	I739V	probably benign	Het
Npnt	T	C	3: 132,885,982	K430R	probably damaging	Het
Nrd1	A	G	4: 109,047,660	N696S	probably benign	Het
Oit3	T	C	10: 59,425,484		probably benign	Het
Olfr1350	A	G	7: 6,570,212	T74A	probably benign	Het
Olfr478	A	T	7: 108,032,121	I74K	possibly damaging	Het
Olfr571	A	G	7: 102,909,719	I40T	possibly damaging	Het
Olfr642	A	G	7: 104,050,169	Y62H	probably damaging	Het
Pkd1	G	A	17: 24,594,821		probably null	Het
Plat	A	G	8: 22,776,828	M279V	probably benign	Het
Prkd1	A	T	12: 50,392,910	L378*	probably null	Het
Rasgef1a	C	T	6: 118,084,545	T157I	probably benign	Het
Rbm22	A	G	18: 60,560,857	N11S	probably damaging	Het
Ros1	T	C	10: 52,046,330		probably benign	Het
Sema6d	T	A	2: 124,653,642	F3Y	unknown	Het
Sis	T	C	3: 72,961,021	D112G	probably benign	Het
Slit1	C	A	19: 41,611,044	G1023C	probably damaging	Het
Sptb	T	C	12: 76,612,555		probably benign	Het
Sspo	T	C	6: 48,498,343	I4881T	probably benign	Het
Supt6	C	A	11: 78,221,143	D1038Y	probably damaging	Het
Tbc1d2b	A	T	9: 90,205,091	L945Q	probably damaging	Het
Tgfbr3	G	T	5: 107,149,898	A212E	probably damaging	Het
Tipin	A	G	9: 64,304,408	T259A	probably benign	Het
Traip	T	C	9: 107,970,472	S365P	probably benign	Het
Tst	T	C	15: 78,399,767	T287A	probably benign	Het
Tube1	C	T	10: 39,145,722		probably benign	Het
Uhrf1bp1l	T	C	10: 89,805,762	S932P	probably benign	Het
Vmn1r37	T	A	6: 66,731,409	N6K	probably damaging	Het
Vmn2r17	C	T	5: 109,453,032	T732I	probably benign	Het
Vmn2r69	A	T	7: 85,406,628	D767E	possibly damaging	Het

Other mutations in Vmn2r111

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00932:Vmn2r111	APN	17	22548753	missense	probably benign	0.00
IGL01306:Vmn2r111	APN	17	22568984	missense	probably damaging	0.99
IGL01309:Vmn2r111	APN	17	22569016	missense	possibly damaging	0.51
IGL01465:Vmn2r111	APN	17	22548737	missense	probably benign	0.00
IGL01505:Vmn2r111	APN	17	22548572	missense	probably benign	0.00
IGL01571:Vmn2r111	APN	17	22571392	missense	probably damaging	0.99
IGL01715:Vmn2r111	APN	17	22569073	splice site	probably benign
IGL01962:Vmn2r111	APN	17	22548284	missense	possibly damaging	0.90
IGL02190:Vmn2r111	APN	17	22570773	missense	probably benign	0.00
IGL02496:Vmn2r111	APN	17	22568856	missense	probably benign
IGL02519:Vmn2r111	APN	17	22548339	missense	possibly damaging	0.80
IGL02616:Vmn2r111	APN	17	22571050	missense	possibly damaging	0.67
IGL02641:Vmn2r111	APN	17	22573224	missense	possibly damaging	0.82
IGL02690:Vmn2r111	APN	17	22559042	critical splice donor site	probably null
IGL02698:Vmn2r111	APN	17	22571245	missense	probably damaging	1.00
IGL03017:Vmn2r111	APN	17	22570858	missense	probably damaging	1.00
R0046:Vmn2r111	UTSW	17	22548009	missense	probably benign
R0064:Vmn2r111	UTSW	17	22572072	missense	probably benign	0.00
R0519:Vmn2r111	UTSW	17	22573121	missense	probably benign	0.02
R1439:Vmn2r111	UTSW	17	22571116	missense	probably benign	0.00
R1467:Vmn2r111	UTSW	17	22571047	missense	probably damaging	0.99
R1467:Vmn2r111	UTSW	17	22571047	missense	probably damaging	0.99
R1636:Vmn2r111	UTSW	17	22571399	missense	probably damaging	1.00
R1647:Vmn2r111	UTSW	17	22569061	missense	probably benign	0.03
R1648:Vmn2r111	UTSW	17	22569061	missense	probably benign	0.03
R1697:Vmn2r111	UTSW	17	22548060	missense	probably benign	0.26
R1996:Vmn2r111	UTSW	17	22548081	missense	probably benign	0.21
R2040:Vmn2r111	UTSW	17	22548414	missense	probably damaging	1.00
R2075:Vmn2r111	UTSW	17	22559062	missense	probably damaging	1.00
R2134:Vmn2r111	UTSW	17	22573104	missense	possibly damaging	0.68
R2357:Vmn2r111	UTSW	17	22559170	splice site	probably benign
R3700:Vmn2r111	UTSW	17	22571161	nonsense	probably null
R3782:Vmn2r111	UTSW	17	22571320	missense	possibly damaging	0.89
R4085:Vmn2r111	UTSW	17	22559115	missense	probably benign	0.00
R4323:Vmn2r111	UTSW	17	22573178	missense	probably benign	0.02
R4900:Vmn2r111	UTSW	17	22548656	missense	possibly damaging	0.94
R5072:Vmn2r111	UTSW	17	22548041	missense	probably damaging	0.99
R5123:Vmn2r111	UTSW	17	22571143	missense	possibly damaging	0.82
R5181:Vmn2r111	UTSW	17	22571020	missense	possibly damaging	0.56
R5357:Vmn2r111	UTSW	17	22548102	nonsense	probably null
R5398:Vmn2r111	UTSW	17	22573271	start codon destroyed	probably null	0.88
R5434:Vmn2r111	UTSW	17	22548489	missense	probably damaging	0.99
R5462:Vmn2r111	UTSW	17	22548257	missense	probably damaging	1.00
R6149:Vmn2r111	UTSW	17	22548815	missense	probably benign	0.00
R6149:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6207:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6281:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6282:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6283:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6307:Vmn2r111	UTSW	17	22573089	missense	probably benign	0.00
R6323:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6325:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6367:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6368:Vmn2r111	UTSW	17	22571908	missense	probably benign	0.38
R6369:Vmn2r111	UTSW	17	22548602	missense	probably damaging	1.00
R6489:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6490:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6546:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6547:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6557:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6654:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6655:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6657:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6659:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6660:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6664:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6798:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6799:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6801:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6893:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6895:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6897:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6922:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6923:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6944:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R6945:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7017:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7018:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7024:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7031:Vmn2r111	UTSW	17	22571245	missense	probably damaging	1.00
R7039:Vmn2r111	UTSW	17	22548184	missense	probably damaging	1.00
R7053:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7054:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7055:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7056:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7145:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7146:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7246:Vmn2r111	UTSW	17	22548714	missense	probably damaging	1.00
R7259:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7260:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7327:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7401:Vmn2r111	UTSW	17	22571086	missense	possibly damaging	0.93
R7514:Vmn2r111	UTSW	17	22548399	missense	probably benign	0.05
R7651:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7781:Vmn2r111	UTSW	17	22570733	missense	probably benign	0.17
R7816:Vmn2r111	UTSW	17	22573102	missense	probably damaging	0.97
R7821:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7838:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
R7921:Vmn2r111	UTSW	17	22559051	missense	possibly damaging	0.50
X0026:Vmn2r111	UTSW	17	22548695	missense	probably damaging	0.98

Posted On

2013-11-11