Incidental Mutation 'IGL01458:Gm5771'
ID84894
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5771
Ensembl Gene ENSMUSG00000058119
Gene Namepredicted gene 5771
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.083) question?
Stock #IGL01458
Quality Score
Status
Chromosome6
Chromosomal Location41392356-41397230 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to G at 41396687 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 161 (D161E)
Ref Sequence ENSEMBL: ENSMUSP00000039684 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000049079]
Predicted Effect probably benign
Transcript: ENSMUST00000049079
AA Change: D161E

PolyPhen 2 Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
SMART Domains Protein: ENSMUSP00000039684
Gene: ENSMUSG00000058119
AA Change: D161E

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
Tryp_SPc 22 238 9.72e-105 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930433N12Rik A T 9: 3,134,008 noncoding transcript Het
Akap12 A G 10: 4,354,060 E290G probably damaging Het
Akap6 T A 12: 52,886,818 C364* probably null Het
Akr1c18 A T 13: 4,137,144 Y198N probably damaging Het
Aurka T C 2: 172,368,979 probably benign Het
Bloc1s6 T A 2: 122,744,215 probably null Het
Clca1 C T 3: 145,007,778 M697I probably benign Het
Csn2 T C 5: 87,696,020 probably benign Het
Dsc1 T C 18: 20,099,138 E271G probably damaging Het
Evi5 G A 5: 107,815,647 A354V probably damaging Het
Fcer2a T A 8: 3,688,151 R137S probably benign Het
Fto A G 8: 91,441,716 T266A probably benign Het
Fzd4 G A 7: 89,404,735 V17I unknown Het
Gadd45b T C 10: 80,931,241 L105P probably damaging Het
Galntl6 T C 8: 58,427,709 S137G probably damaging Het
Gm2022 A T 12: 87,895,388 K7* probably null Het
Gpr135 T C 12: 72,069,668 M442V probably benign Het
Kcnq1 T A 7: 143,194,278 Y330* probably null Het
Kdm5b A G 1: 134,621,986 R1106G possibly damaging Het
Lrrc8e C T 8: 4,236,141 R789W probably damaging Het
Myo16 T C 8: 10,435,853 L644P probably damaging Het
Nbeal1 G T 1: 60,242,625 probably null Het
Nlrp4c T C 7: 6,100,784 C906R possibly damaging Het
Olfr1118 C T 2: 87,309,482 T251I probably damaging Het
Olfr344 T A 2: 36,568,742 L48H probably damaging Het
Olfr389 A T 11: 73,776,706 I207N probably benign Het
Ovgp1 A G 3: 105,974,991 N70D probably benign Het
Panx3 A T 9: 37,661,147 M369K probably damaging Het
Plet1 A G 9: 50,494,717 N52S probably benign Het
Psg18 A T 7: 18,354,816 M1K probably null Het
Ptprz1 A T 6: 22,972,844 D251V probably damaging Het
Serpinb6a A G 13: 33,930,081 Y88H possibly damaging Het
Siglecf G A 7: 43,355,138 R297Q possibly damaging Het
Tbx15 T C 3: 99,316,228 V244A probably damaging Het
Top2a A T 11: 99,011,030 L458Q probably damaging Het
Trim39 A G 17: 36,263,963 probably benign Het
Vps37c T C 19: 10,710,417 C81R probably damaging Het
Wdr62 A T 7: 30,241,762 S744T probably benign Het
Zyg11a G A 4: 108,204,902 T234I probably damaging Het
Other mutations in Gm5771
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00330:Gm5771 APN 6 41394773 missense probably damaging 1.00
IGL00586:Gm5771 APN 6 41396115 missense probably damaging 1.00
IGL01103:Gm5771 APN 6 41397157 missense probably damaging 1.00
IGL01368:Gm5771 APN 6 41396686 missense possibly damaging 0.94
IGL03114:Gm5771 APN 6 41397078 missense probably damaging 1.00
R0167:Gm5771 UTSW 6 41396261 splice site probably benign
R1548:Gm5771 UTSW 6 41396011 missense probably damaging 1.00
R4584:Gm5771 UTSW 6 41396767 missense probably benign 0.35
R5622:Gm5771 UTSW 6 41396150 missense probably damaging 1.00
R5664:Gm5771 UTSW 6 41394671 missense probably benign 0.04
R6222:Gm5771 UTSW 6 41397166 missense probably damaging 0.98
R6325:Gm5771 UTSW 6 41396656 missense probably benign 0.00
R7816:Gm5771 UTSW 6 41394773 missense probably damaging 1.00
R7986:Gm5771 UTSW 6 41396124 missense probably damaging 1.00
R8016:Gm5771 UTSW 6 41397166 missense probably damaging 0.98
Posted On2013-11-11