Incidental Mutation 'IGL01478:Igsf23'
ID88531
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Igsf23
Ensembl Gene ENSMUSG00000040498
Gene Nameimmunoglobulin superfamily, member 23
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.106) question?
Stock #IGL01478
Quality Score
Status
Chromosome7
Chromosomal Location19937305-19950756 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) G to A at 19938236 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000147077 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000043440] [ENSMUST00000208974]
Predicted Effect probably benign
Transcript: ENSMUST00000043440
SMART Domains Protein: ENSMUSP00000047914
Gene: ENSMUSG00000040498

DomainStartEndE-ValueType
signal peptide 1 34 N/A INTRINSIC
IG 107 181 2.71e0 SMART
low complexity region 182 195 N/A INTRINSIC
transmembrane domain 213 235 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000207513
Predicted Effect noncoding transcript
Transcript: ENSMUST00000208210
Predicted Effect probably benign
Transcript: ENSMUST00000208974
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Nov 2011]
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930590J08Rik A G 6: 91,934,609 T613A probably benign Het
Cdh16 G T 8: 104,614,488 probably benign Het
Epn2 A G 11: 61,523,086 S419P probably benign Het
Eral1 A T 11: 78,075,732 V234D probably damaging Het
Fhad1 T C 4: 141,951,638 K576E possibly damaging Het
Frmd4b T A 6: 97,328,293 D170V probably damaging Het
Gm4353 A G 7: 116,083,740 V202A possibly damaging Het
Ighmbp2 A G 19: 3,274,531 I245T probably benign Het
Krt1 A G 15: 101,846,286 probably benign Het
Mapk8 A G 14: 33,383,900 V371A probably benign Het
Mtrf1 T G 14: 79,402,920 probably benign Het
Myzap A G 9: 71,515,067 probably null Het
Nsrp1 C T 11: 77,050,652 V73I probably benign Het
Olfr1089 A T 2: 86,733,329 Y94* probably null Het
Olfr344 T A 2: 36,568,742 L48H probably damaging Het
Olfr670 A G 7: 104,960,348 I128T probably damaging Het
Pex6 C T 17: 46,725,304 R976C probably benign Het
Ranbp9 G A 13: 43,414,084 T546I probably benign Het
Rfx5 T C 3: 94,958,440 V350A possibly damaging Het
Rnf19b A G 4: 129,058,830 E187G probably damaging Het
Sbf1 A G 15: 89,299,743 V1217A probably damaging Het
Sfmbt1 T A 14: 30,811,521 D618E probably damaging Het
Sipa1l1 A G 12: 82,446,898 E1697G probably benign Het
Syk A G 13: 52,624,748 Y290C probably benign Het
Trim69 T C 2: 122,178,443 L328P probably damaging Het
Unc5c T A 3: 141,828,451 I911N probably damaging Het
Wdr5 T C 2: 27,533,832 V294A probably damaging Het
Other mutations in Igsf23
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0334:Igsf23 UTSW 7 19941753 missense probably benign 0.27
R0831:Igsf23 UTSW 7 19941737 splice site probably benign
R2351:Igsf23 UTSW 7 19944798 nonsense probably null
R4835:Igsf23 UTSW 7 19941830 missense possibly damaging 0.80
R4850:Igsf23 UTSW 7 19953934 unclassified probably benign
R6739:Igsf23 UTSW 7 19944748 missense probably damaging 0.97
R6924:Igsf23 UTSW 7 19941759 missense possibly damaging 0.83
R8244:Igsf23 UTSW 7 19941873 missense possibly damaging 0.66
R8285:Igsf23 UTSW 7 19941956 missense possibly damaging 0.90
Posted On2013-11-18