Incidental Mutation 'IGL01478:Igsf23'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Igsf23
Ensembl Gene ENSMUSG00000040498
Gene Nameimmunoglobulin superfamily, member 23
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.106) question?
Stock #IGL01478
Quality Score
Chromosomal Location19937305-19950756 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) G to A at 19938236 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000147077 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000043440] [ENSMUST00000208974]
Predicted Effect probably benign
Transcript: ENSMUST00000043440
SMART Domains Protein: ENSMUSP00000047914
Gene: ENSMUSG00000040498

signal peptide 1 34 N/A INTRINSIC
IG 107 181 2.71e0 SMART
low complexity region 182 195 N/A INTRINSIC
transmembrane domain 213 235 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000207513
Predicted Effect noncoding transcript
Transcript: ENSMUST00000208210
Predicted Effect probably benign
Transcript: ENSMUST00000208974
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Nov 2011]
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930590J08Rik A G 6: 91,934,609 T613A probably benign Het
Cdh16 G T 8: 104,614,488 probably benign Het
Epn2 A G 11: 61,523,086 S419P probably benign Het
Eral1 A T 11: 78,075,732 V234D probably damaging Het
Fhad1 T C 4: 141,951,638 K576E possibly damaging Het
Frmd4b T A 6: 97,328,293 D170V probably damaging Het
Gm4353 A G 7: 116,083,740 V202A possibly damaging Het
Ighmbp2 A G 19: 3,274,531 I245T probably benign Het
Krt1 A G 15: 101,846,286 probably benign Het
Mapk8 A G 14: 33,383,900 V371A probably benign Het
Mtrf1 T G 14: 79,402,920 probably benign Het
Myzap A G 9: 71,515,067 probably null Het
Nsrp1 C T 11: 77,050,652 V73I probably benign Het
Olfr1089 A T 2: 86,733,329 Y94* probably null Het
Olfr344 T A 2: 36,568,742 L48H probably damaging Het
Olfr670 A G 7: 104,960,348 I128T probably damaging Het
Pex6 C T 17: 46,725,304 R976C probably benign Het
Ranbp9 G A 13: 43,414,084 T546I probably benign Het
Rfx5 T C 3: 94,958,440 V350A possibly damaging Het
Rnf19b A G 4: 129,058,830 E187G probably damaging Het
Sbf1 A G 15: 89,299,743 V1217A probably damaging Het
Sfmbt1 T A 14: 30,811,521 D618E probably damaging Het
Sipa1l1 A G 12: 82,446,898 E1697G probably benign Het
Syk A G 13: 52,624,748 Y290C probably benign Het
Trim69 T C 2: 122,178,443 L328P probably damaging Het
Unc5c T A 3: 141,828,451 I911N probably damaging Het
Wdr5 T C 2: 27,533,832 V294A probably damaging Het
Other mutations in Igsf23
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0334:Igsf23 UTSW 7 19941753 missense probably benign 0.27
R0831:Igsf23 UTSW 7 19941737 splice site probably benign
R2351:Igsf23 UTSW 7 19944798 nonsense probably null
R4835:Igsf23 UTSW 7 19941830 missense possibly damaging 0.80
R4850:Igsf23 UTSW 7 19953934 unclassified probably benign
R6739:Igsf23 UTSW 7 19944748 missense probably damaging 0.97
R6924:Igsf23 UTSW 7 19941759 missense possibly damaging 0.83
R8244:Igsf23 UTSW 7 19941873 missense possibly damaging 0.66
R8285:Igsf23 UTSW 7 19941956 missense possibly damaging 0.90
Posted On2013-11-18