Incidental Mutation 'IGL01485:Vmn1r234'
ID88717
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r234
Ensembl Gene ENSMUSG00000057203
Gene Namevomeronasal 1 receptor 234
SynonymsV1rf1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.056) question?
Stock #IGL01485
Quality Score
Status
Chromosome17
Chromosomal Location21228826-21229815 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 21228909 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 28 (D28E)
Ref Sequence ENSEMBL: ENSMUSP00000078579 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000079633]
Predicted Effect possibly damaging
Transcript: ENSMUST00000079633
AA Change: D28E

PolyPhen 2 Score 0.533 (Sensitivity: 0.88; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203
AA Change: D28E

DomainStartEndE-ValueType
Pfam:TAS2R 25 315 2.8e-14 PFAM
Pfam:V1R 57 318 2.3e-26 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000177028
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930590J08Rik C T 6: 91,950,022 L888F probably damaging Het
Aftph G T 11: 20,692,507 A842E probably damaging Het
Ankrd13d A T 19: 4,273,564 M257K probably benign Het
Anks1 T C 17: 28,051,584 F786L probably damaging Het
Cd2ap A T 17: 42,852,474 I20N probably damaging Het
Cdh20 C T 1: 104,934,107 T4M probably benign Het
Dnah5 C T 15: 28,331,726 R2153C probably damaging Het
Fap G A 2: 62,544,311 P248L possibly damaging Het
Gm853 T A 4: 130,215,425 Y274F probably benign Het
Hps4 T A 5: 112,364,511 probably benign Het
Igdcc4 C A 9: 65,122,607 T313K probably benign Het
Klhl30 G A 1: 91,354,039 V121I probably damaging Het
Ldb3 C A 14: 34,542,562 E526D probably damaging Het
Lhfpl4 T A 6: 113,194,121 I35F probably benign Het
Lpin1 A G 12: 16,562,357 probably benign Het
Nek1 T A 8: 61,049,826 C436S probably benign Het
Nek5 C A 8: 22,083,369 A524S probably benign Het
Nkx2-3 C T 19: 43,612,655 T52M possibly damaging Het
Olfr1364 A T 13: 21,574,457 probably null Het
Olfr393 A G 11: 73,847,210 I305T probably benign Het
Olfr923 G A 9: 38,828,599 V303I possibly damaging Het
Pappa T C 4: 65,189,299 V649A probably damaging Het
Parp4 T A 14: 56,622,204 Y920N possibly damaging Het
Pdgfra G A 5: 75,163,652 S56N probably benign Het
Pigg T C 5: 108,336,201 V438A possibly damaging Het
Ptn A T 6: 36,743,363 C85S probably damaging Het
Sh3rf1 A C 8: 61,329,331 E169A possibly damaging Het
Slc30a10 T A 1: 185,455,419 V119E probably damaging Het
Speg A G 1: 75,387,827 E178G probably damaging Het
Sspo A G 6: 48,478,731 Y3105C probably damaging Het
Supt3 A G 17: 45,119,158 E366G possibly damaging Het
Top2a A T 11: 99,011,030 L458Q probably damaging Het
Ttc21b G A 2: 66,251,890 probably benign Het
Usp24 T C 4: 106,362,232 F542L probably benign Het
Other mutations in Vmn1r234
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00089:Vmn1r234 APN 17 21229598 missense possibly damaging 0.95
IGL02149:Vmn1r234 APN 17 21229007 missense probably benign 0.00
IGL02291:Vmn1r234 APN 17 21228931 missense probably benign 0.28
IGL02993:Vmn1r234 APN 17 21229703 missense probably damaging 0.99
IGL03223:Vmn1r234 APN 17 21229391 missense probably damaging 0.98
R0626:Vmn1r234 UTSW 17 21229745 missense probably benign 0.17
R1274:Vmn1r234 UTSW 17 21229251 frame shift probably null
R1275:Vmn1r234 UTSW 17 21229251 frame shift probably null
R1288:Vmn1r234 UTSW 17 21229251 frame shift probably null
R1289:Vmn1r234 UTSW 17 21229251 frame shift probably null
R1319:Vmn1r234 UTSW 17 21228910 missense probably benign 0.01
R1412:Vmn1r234 UTSW 17 21229250 missense probably benign 0.01
R2323:Vmn1r234 UTSW 17 21229703 missense probably benign 0.10
R3755:Vmn1r234 UTSW 17 21229009 missense probably damaging 0.98
R4299:Vmn1r234 UTSW 17 21229021 missense probably benign 0.03
R5301:Vmn1r234 UTSW 17 21229327 missense probably benign 0.11
R5741:Vmn1r234 UTSW 17 21229469 missense probably benign 0.21
R6197:Vmn1r234 UTSW 17 21229327 missense probably benign 0.04
R6218:Vmn1r234 UTSW 17 21229721 missense possibly damaging 0.71
R6486:Vmn1r234 UTSW 17 21229342 missense probably benign 0.11
R7482:Vmn1r234 UTSW 17 21229375 missense probably benign 0.07
R7635:Vmn1r234 UTSW 17 21229217 missense probably damaging 1.00
R8295:Vmn1r234 UTSW 17 21228839 missense probably benign 0.01
X0028:Vmn1r234 UTSW 17 21228890 missense probably benign 0.17
Posted On2013-11-18