Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01508:Pate4'

89106

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Pate4

Ensembl Gene

ENSMUSG00000032099

Gene Name

prostate and testis expressed 4

Synonyms

Svs7, Pate-B, 9530004K16Rik, SVS VII

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01508

Quality Score

Status

Chromosome

Chromosomal Location

35518387-35523164 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 35519602 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 29 (C29*)

Ref Sequence

ENSEMBL: ENSMUSP00000034610 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000034610] [ENSMUST00000098906]

AlphaFold

Q09098

Predicted Effect

probably null
Transcript: ENSMUST00000034610
AA Change: C29*

SMART Domains

Protein: ENSMUSP00000034610
Gene: ENSMUSG00000032099
AA Change: C29*

Domain	Start	End	E-Value	Type
signal peptide	1	23	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000098906

SMART Domains

Protein: ENSMUSP00000096505
Gene: ENSMUSG00000074452

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000137309

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knockout allele do not exhibit defects in viability, bone formation or remodeling, organ gross morphology or fertility. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	C	T	6: 121,636,326 (GRCm39)	R732*	probably null	Het
Adarb2	C	A	13: 8,802,606 (GRCm39)		probably null	Het
Alb	C	T	5: 90,618,697 (GRCm39)	A430V	probably benign	Het
Cdhr3	A	T	12: 33,103,427 (GRCm39)	F397I	possibly damaging	Het
Cmya5	A	G	13: 93,230,535 (GRCm39)	S1518P	probably benign	Het
Col6a4	T	A	9: 105,890,804 (GRCm39)	Y1830F	possibly damaging	Het
Col6a6	A	G	9: 105,604,365 (GRCm39)		probably benign	Het
Dnah7a	T	C	1: 53,666,231 (GRCm39)	S599G	probably benign	Het
Dnai4	G	A	4: 102,929,884 (GRCm39)	P369L	possibly damaging	Het
Fbxo3	A	T	2: 103,864,021 (GRCm39)	H92L	probably benign	Het
Ffar2	T	C	7: 30,518,601 (GRCm39)	D313G	probably benign	Het
Fnta	T	C	8: 26,497,294 (GRCm39)	E185G	probably damaging	Het
Gdap2	C	T	3: 100,078,243 (GRCm39)	T69I	possibly damaging	Het
Gimap7	A	T	6: 48,701,230 (GRCm39)	N272I	probably damaging	Het
Gin1	T	C	1: 97,705,162 (GRCm39)	V84A	probably benign	Het
Itga8	A	G	2: 12,237,613 (GRCm39)	L369P	possibly damaging	Het
Itgax	C	T	7: 127,743,990 (GRCm39)	T891I	probably damaging	Het
Lama1	T	A	17: 68,116,356 (GRCm39)		probably benign	Het
Lkaaear1	T	C	2: 181,338,830 (GRCm39)	T169A	probably benign	Het
Nckap5	A	G	1: 125,953,309 (GRCm39)	V1017A	probably damaging	Het
Nemf	A	C	12: 69,391,760 (GRCm39)		probably benign	Het
Osr1	A	G	12: 9,629,370 (GRCm39)	D81G	probably damaging	Het
Prkce	C	T	17: 86,937,513 (GRCm39)	R649C	probably damaging	Het
Ptpn5	A	G	7: 46,741,303 (GRCm39)	V14A	probably benign	Het
Rnf166	C	A	8: 123,197,081 (GRCm39)	C57F	probably damaging	Het
Tenm3	A	G	8: 48,729,680 (GRCm39)	I1426T	probably benign	Het
Trpm6	C	T	19: 18,773,894 (GRCm39)	Q424*	probably null	Het
Ttc27	T	A	17: 75,142,352 (GRCm39)	S606T	probably damaging	Het
Tyrp1	T	C	4: 80,759,002 (GRCm39)	S292P	possibly damaging	Het
Wdr70	A	G	15: 8,108,747 (GRCm39)	V133A	probably benign	Het
Ylpm1	T	C	12: 85,062,229 (GRCm39)	F252S	possibly damaging	Het

Other mutations in Pate4

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0096:Pate4	UTSW	9	35,523,130 (GRCm39)	missense	probably damaging	1.00
R2091:Pate4	UTSW	9	35,519,553 (GRCm39)	missense	possibly damaging	0.84
R3912:Pate4	UTSW	9	35,523,140 (GRCm39)	start codon destroyed	probably null	0.82
R3913:Pate4	UTSW	9	35,523,140 (GRCm39)	start codon destroyed	probably null	0.82
R4864:Pate4	UTSW	9	35,519,535 (GRCm39)	missense	probably damaging	1.00
R5443:Pate4	UTSW	9	35,519,170 (GRCm39)	missense	possibly damaging	0.74
R6182:Pate4	UTSW	9	35,519,586 (GRCm39)	missense	possibly damaging	0.79
R6273:Pate4	UTSW	9	35,519,086 (GRCm39)	missense	probably benign	0.02
R7622:Pate4	UTSW	9	35,519,595 (GRCm39)	missense	possibly damaging	0.90
R9507:Pate4	UTSW	9	35,519,538 (GRCm39)	missense	probably damaging	0.99

Posted On

2013-12-03