Incidental Mutation 'IGL01509:Slc16a4'
ID89155
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc16a4
Ensembl Gene ENSMUSG00000027896
Gene Namesolute carrier family 16 (monocarboxylic acid transporters), member 4
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01509
Quality Score
Status
Chromosome3
Chromosomal Location107291230-107312115 bp(+) (GRCm38)
Type of Mutationcritical splice acceptor site
DNA Base Change (assembly) A to C at 107311434 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000029502 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000029502] [ENSMUST00000029502] [ENSMUST00000106723]
Predicted Effect probably null
Transcript: ENSMUST00000029502
SMART Domains Protein: ENSMUSP00000029502
Gene: ENSMUSG00000027896

DomainStartEndE-ValueType
Pfam:MFS_1 27 373 8.2e-26 PFAM
Pfam:MFS_1 305 499 2e-17 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000029502
SMART Domains Protein: ENSMUSP00000029502
Gene: ENSMUSG00000027896

DomainStartEndE-ValueType
Pfam:MFS_1 27 373 8.2e-26 PFAM
Pfam:MFS_1 305 499 2e-17 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000106723
SMART Domains Protein: ENSMUSP00000102334
Gene: ENSMUSG00000027896

DomainStartEndE-ValueType
Pfam:MFS_1 27 375 2.1e-28 PFAM
Pfam:MFS_1 327 462 3.6e-11 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A4gnt T A 9: 99,613,766 I85N probably benign Het
Bbof1 T A 12: 84,411,085 N41K possibly damaging Het
Cdh10 A G 15: 18,986,798 K372E possibly damaging Het
Clmn T A 12: 104,780,903 Q795L probably benign Het
Enox1 T C 14: 77,699,273 S583P probably damaging Het
Fam208a T C 14: 27,459,774 probably benign Het
Hmcn1 C T 1: 150,609,631 G4407S probably damaging Het
Ifi206 T A 1: 173,485,576 M109L probably benign Het
Ighmbp2 A G 19: 3,268,711 M455T possibly damaging Het
Inpp4b T C 8: 81,890,703 probably benign Het
Mctp2 A G 7: 72,259,269 S99P probably benign Het
Mrgprb2 G A 7: 48,552,926 T17M possibly damaging Het
Ogdhl T A 14: 32,337,759 M410K probably damaging Het
Pard3b A T 1: 62,161,248 R315S possibly damaging Het
Pde3b A G 7: 114,518,410 Q625R probably benign Het
Plxna3 A G X: 74,332,433 Q355R probably benign Het
Ptprm A T 17: 66,762,213 F907I possibly damaging Het
Vmn1r82 A T 7: 12,305,169 H123L probably damaging Het
Vmn2r1 T C 3: 64,103,045 I568T probably benign Het
Wdr78 G A 4: 103,072,687 P369L possibly damaging Het
Zfp7 G A 15: 76,881,133 V9M probably damaging Het
Zfp759 A G 13: 67,139,594 N403S probably benign Het
Other mutations in Slc16a4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01065:Slc16a4 APN 3 107303100 missense possibly damaging 0.67
IGL01311:Slc16a4 APN 3 107292505 missense possibly damaging 0.83
IGL01780:Slc16a4 APN 3 107303099 missense probably benign 0.00
IGL02294:Slc16a4 APN 3 107301068 missense probably benign 0.00
IGL02350:Slc16a4 APN 3 107303099 missense probably benign 0.00
IGL02357:Slc16a4 APN 3 107303099 missense probably benign 0.00
IGL02792:Slc16a4 APN 3 107298877 missense probably benign
IGL02873:Slc16a4 APN 3 107300795 missense probably benign 0.00
IGL03001:Slc16a4 APN 3 107311542 missense possibly damaging 0.91
IGL03002:Slc16a4 APN 3 107300786 missense probably benign 0.07
R0370:Slc16a4 UTSW 3 107301097 missense possibly damaging 0.66
R0525:Slc16a4 UTSW 3 107297939 splice site probably benign
R1192:Slc16a4 UTSW 3 107298873 missense probably benign 0.07
R1458:Slc16a4 UTSW 3 107300932 missense probably benign 0.00
R1939:Slc16a4 UTSW 3 107301001 missense probably benign 0.00
R2061:Slc16a4 UTSW 3 107300711 missense probably benign 0.00
R2098:Slc16a4 UTSW 3 107300847 nonsense probably null
R2102:Slc16a4 UTSW 3 107304503 splice site probably null
R3411:Slc16a4 UTSW 3 107300872 missense probably benign
R4983:Slc16a4 UTSW 3 107300860 missense probably benign 0.00
R5394:Slc16a4 UTSW 3 107292442 missense probably benign
R5804:Slc16a4 UTSW 3 107298964 missense probably benign 0.04
R6077:Slc16a4 UTSW 3 107301065 missense possibly damaging 0.91
R6626:Slc16a4 UTSW 3 107301196 missense possibly damaging 0.95
R6693:Slc16a4 UTSW 3 107303064 missense probably damaging 1.00
R6811:Slc16a4 UTSW 3 107298917 missense probably benign 0.06
R6823:Slc16a4 UTSW 3 107311498 missense probably benign 0.02
R6982:Slc16a4 UTSW 3 107299273 missense probably benign 0.01
R7050:Slc16a4 UTSW 3 107300832 missense probably benign
R7103:Slc16a4 UTSW 3 107311471 missense probably damaging 1.00
R7608:Slc16a4 UTSW 3 107303127 missense probably damaging 1.00
R7623:Slc16a4 UTSW 3 107297981 missense possibly damaging 0.71
X0018:Slc16a4 UTSW 3 107300815 missense probably benign 0.01
Posted On2013-12-03