Incidental Mutation 'IGL01512:Zfp791'
| ID |
89267 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp791
|
| Ensembl Gene |
ENSMUSG00000074194 |
| Gene Name |
zinc finger protein 791 |
| Synonyms |
EG244556 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01512
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
8 |
| Chromosomal Location |
85835182-85849724 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 85840172 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 32
(V32M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000147335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098550]
[ENSMUST00000211109]
|
| AlphaFold |
Q497V9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000098550
AA Change: V32M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000096150
Gene: ENSMUSG00000074194
AA Change: V32M
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
64 |
4.26e-18 |
SMART |
|
ZnF_C2H2
|
102 |
124 |
2.53e-2 |
SMART |
|
ZnF_C2H2
|
139 |
161 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
167 |
189 |
3.34e-2 |
SMART |
|
ZnF_C2H2
|
195 |
217 |
2.79e-4 |
SMART |
|
ZnF_C2H2
|
223 |
245 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
251 |
273 |
2.12e-4 |
SMART |
|
ZnF_C2H2
|
281 |
303 |
2.02e-1 |
SMART |
|
ZnF_C2H2
|
309 |
331 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
337 |
359 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
365 |
387 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
393 |
415 |
1.13e-4 |
SMART |
|
ZnF_C2H2
|
421 |
443 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
449 |
471 |
2.05e-2 |
SMART |
|
ZnF_C2H2
|
477 |
499 |
3.95e-4 |
SMART |
|
ZnF_C2H2
|
505 |
527 |
2.71e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000158588
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000211109
AA Change: V32M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 18 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
T |
C |
11: 110,208,649 (GRCm39) |
I223V |
probably benign |
Het |
| Abra |
T |
C |
15: 41,729,413 (GRCm39) |
E329G |
probably damaging |
Het |
| Ahsa2 |
C |
T |
11: 23,441,582 (GRCm39) |
A163T |
probably benign |
Het |
| Atxn1 |
T |
C |
13: 45,720,077 (GRCm39) |
Q606R |
probably damaging |
Het |
| Fads1 |
T |
A |
19: 10,160,506 (GRCm39) |
S31T |
probably benign |
Het |
| Il6st |
T |
A |
13: 112,640,900 (GRCm39) |
M831K |
probably benign |
Het |
| Lztr1 |
G |
A |
16: 17,340,255 (GRCm39) |
|
probably null |
Het |
| Megf6 |
G |
A |
4: 154,347,040 (GRCm39) |
R755Q |
possibly damaging |
Het |
| Ndn |
T |
G |
7: 61,998,481 (GRCm39) |
L109R |
probably damaging |
Het |
| Or2b4 |
T |
G |
17: 38,116,503 (GRCm39) |
S156A |
probably damaging |
Het |
| Or4c52 |
A |
G |
2: 89,845,636 (GRCm39) |
I121V |
probably damaging |
Het |
| Psmd6 |
T |
C |
14: 14,114,237 (GRCm38) |
Y294C |
probably damaging |
Het |
| Serpina6 |
A |
G |
12: 103,620,318 (GRCm39) |
Y144H |
probably damaging |
Het |
| Top3b |
T |
C |
16: 16,709,286 (GRCm39) |
I68T |
possibly damaging |
Het |
| Trav6d-4 |
G |
A |
14: 52,990,870 (GRCm39) |
V6I |
probably benign |
Het |
| Utp3 |
T |
C |
5: 88,703,803 (GRCm39) |
V444A |
probably damaging |
Het |
| Wdr72 |
T |
C |
9: 74,056,041 (GRCm39) |
V299A |
probably benign |
Het |
| Zfp9 |
A |
G |
6: 118,444,292 (GRCm39) |
F17S |
probably damaging |
Het |
|
| Other mutations in Zfp791 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
R0004:Zfp791
|
UTSW |
8 |
85,837,495 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0085:Zfp791
|
UTSW |
8 |
85,838,862 (GRCm39) |
nonsense |
probably null |
|
|
R0496:Zfp791
|
UTSW |
8 |
85,836,609 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1196:Zfp791
|
UTSW |
8 |
85,837,583 (GRCm39) |
nonsense |
probably null |
|
|
R1927:Zfp791
|
UTSW |
8 |
85,837,312 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4240:Zfp791
|
UTSW |
8 |
85,836,295 (GRCm39) |
missense |
probably null |
1.00 |
|
R4370:Zfp791
|
UTSW |
8 |
85,840,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4637:Zfp791
|
UTSW |
8 |
85,836,514 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4684:Zfp791
|
UTSW |
8 |
85,837,559 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4713:Zfp791
|
UTSW |
8 |
85,837,597 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4822:Zfp791
|
UTSW |
8 |
85,837,035 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4914:Zfp791
|
UTSW |
8 |
85,837,580 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4915:Zfp791
|
UTSW |
8 |
85,837,580 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4916:Zfp791
|
UTSW |
8 |
85,837,580 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4918:Zfp791
|
UTSW |
8 |
85,837,580 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5106:Zfp791
|
UTSW |
8 |
85,837,259 (GRCm39) |
nonsense |
probably null |
|
|
R5549:Zfp791
|
UTSW |
8 |
85,836,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6093:Zfp791
|
UTSW |
8 |
85,840,135 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6362:Zfp791
|
UTSW |
8 |
85,846,279 (GRCm39) |
start gained |
probably benign |
|
|
R7737:Zfp791
|
UTSW |
8 |
85,838,844 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8986:Zfp791
|
UTSW |
8 |
85,837,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9050:Zfp791
|
UTSW |
8 |
85,837,334 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
| Posted On |
2013-12-03 |
Incidental Mutation