Incidental Mutation 'IGL01514:Accs'
ID89328
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Accs
Ensembl Gene ENSMUSG00000040272
Gene Name1-aminocyclopropane-1-carboxylate synthase (non-functional)
Synonyms2610203E10Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.067) question?
Stock #IGL01514
Quality Score
Status
Chromosome2
Chromosomal Location93833467-93849943 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 93839242 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000041593] [ENSMUST00000068513] [ENSMUST00000111246] [ENSMUST00000130077]
Predicted Effect probably benign
Transcript: ENSMUST00000041593
SMART Domains Protein: ENSMUSP00000036268
Gene: ENSMUSG00000040272

DomainStartEndE-ValueType
low complexity region 35 43 N/A INTRINSIC
Pfam:Aminotran_1_2 74 448 1.9e-59 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000068513
SMART Domains Protein: ENSMUSP00000065389
Gene: ENSMUSG00000040272

DomainStartEndE-ValueType
low complexity region 35 43 N/A INTRINSIC
Pfam:Aminotran_1_2 74 448 1.9e-59 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000111246
SMART Domains Protein: ENSMUSP00000106877
Gene: ENSMUSG00000040272

DomainStartEndE-ValueType
low complexity region 58 66 N/A INTRINSIC
Pfam:Aminotran_1_2 97 471 2.1e-58 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000128719
Predicted Effect probably benign
Transcript: ENSMUST00000130077
SMART Domains Protein: ENSMUSP00000114687
Gene: ENSMUSG00000040272

DomainStartEndE-ValueType
low complexity region 35 43 N/A INTRINSIC
Pfam:Aminotran_1_2 74 157 2.5e-8 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000140018
Predicted Effect noncoding transcript
Transcript: ENSMUST00000141413
Predicted Effect noncoding transcript
Transcript: ENSMUST00000146045
Predicted Effect noncoding transcript
Transcript: ENSMUST00000146436
Predicted Effect noncoding transcript
Transcript: ENSMUST00000149073
Predicted Effect probably benign
Transcript: ENSMUST00000150666
SMART Domains Protein: ENSMUSP00000119096
Gene: ENSMUSG00000040272

DomainStartEndE-ValueType
SCOP:d1b8ga_ 2 72 7e-9 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Actl7b T C 4: 56,740,677 Y227C probably damaging Het
Adam26a A T 8: 43,568,448 H668Q probably benign Het
Alcam A T 16: 52,274,290 probably benign Het
Aldh3a2 C T 11: 61,253,798 probably benign Het
Atp11b G T 3: 35,836,981 G801V probably damaging Het
C3 G A 17: 57,215,866 T1006I probably benign Het
Cacna2d4 T C 6: 119,282,173 probably benign Het
Cldn34b3 A T X: 76,267,074 I83F probably damaging Het
Clec2g G A 6: 128,948,773 M48I probably benign Het
Coch A G 12: 51,603,353 D375G probably damaging Het
Erbb2 C T 11: 98,432,919 T653I possibly damaging Het
Etv3 A G 3: 87,535,718 H203R possibly damaging Het
Fat4 A G 3: 38,949,534 R1801G possibly damaging Het
Gars T A 6: 55,065,520 S413T probably benign Het
Gnat1 G A 9: 107,676,301 R253C possibly damaging Het
Hook3 A T 8: 26,088,189 L91I possibly damaging Het
Lrp8 T C 4: 107,855,684 Y377H probably damaging Het
Lztr1 G A 16: 17,522,391 probably null Het
Malt1 A G 18: 65,476,400 D825G possibly damaging Het
Nlrp9b T C 7: 20,045,934 probably null Het
Olfr1396 A T 11: 49,113,576 I50N probably damaging Het
Olfr54 C T 11: 51,027,589 R196* probably null Het
Orc1 A G 4: 108,602,052 R473G probably damaging Het
Pard6g G A 18: 80,117,446 R258H probably damaging Het
Pkdrej T C 15: 85,818,063 D1224G possibly damaging Het
Polr1e A G 4: 45,018,723 T18A probably benign Het
Pycrl T C 15: 75,917,004 T240A probably damaging Het
Ralgapa1 C A 12: 55,719,657 G1284V probably damaging Het
Rcl1 T C 19: 29,143,298 probably benign Het
Sec24c C T 14: 20,682,771 T134I possibly damaging Het
Sis A G 3: 72,935,920 probably benign Het
Susd5 A C 9: 114,068,879 probably benign Het
Tlk1 T C 2: 70,752,266 N173S probably benign Het
Uroc1 T C 6: 90,363,100 probably benign Het
Other mutations in Accs
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02704:Accs APN 2 93842926 missense probably damaging 0.99
IGL02724:Accs APN 2 93845776 missense probably damaging 1.00
IGL02929:Accs APN 2 93844221 missense probably damaging 1.00
PIT4243001:Accs UTSW 2 93841334 missense probably benign
R0043:Accs UTSW 2 93841885 missense probably benign 0.03
R0644:Accs UTSW 2 93839229 missense probably damaging 1.00
R1712:Accs UTSW 2 93848103 missense probably damaging 0.96
R2215:Accs UTSW 2 93841898 missense probably benign 0.00
R4755:Accs UTSW 2 93841337 missense probably damaging 1.00
R4852:Accs UTSW 2 93844260 missense probably damaging 1.00
R4997:Accs UTSW 2 93841883 nonsense probably null
R5287:Accs UTSW 2 93835953 missense probably damaging 1.00
R5556:Accs UTSW 2 93836083 missense probably damaging 1.00
R5760:Accs UTSW 2 93845760 missense probably damaging 1.00
R5942:Accs UTSW 2 93836047 missense probably damaging 1.00
R5972:Accs UTSW 2 93839227 missense probably damaging 1.00
R6820:Accs UTSW 2 93842921 missense probably null 1.00
R7513:Accs UTSW 2 93840092 missense possibly damaging 0.94
R7861:Accs UTSW 2 93835732 makesense probably null
R7947:Accs UTSW 2 93844257 missense probably damaging 1.00
R8038:Accs UTSW 2 93842917 critical splice donor site probably null
R8404:Accs UTSW 2 93838115 missense probably damaging 1.00
R8502:Accs UTSW 2 93838115 missense probably damaging 1.00
Z1177:Accs UTSW 2 93848153 missense probably benign 0.00
Posted On2013-12-03