Incidental Mutation 'IGL01518:4933427I04Rik'
ID89387
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 4933427I04Rik
Ensembl Gene ENSMUSG00000073761
Gene NameRiken cDNA 4933427I04 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL01518
Quality Score
Status
Chromosome4
Chromosomal Location123859679-123863165 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 123860701 bp
ZygosityHeterozygous
Amino Acid Change Glutamic Acid to Valine at position 136 (E136V)
Ref Sequence ENSEMBL: ENSMUSP00000095506 (fasta)
Predicted Effect probably benign
Transcript: ENSMUST00000097896
AA Change: E136V

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
Predicted Effect noncoding transcript
Transcript: ENSMUST00000137546
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930447F04Rik A C X: 66,304,054 V16G unknown Het
Aadac A G 3: 60,035,899 D75G probably damaging Het
Arfgap1 T A 2: 180,972,725 S125T probably benign Het
Atxn2 G T 5: 121,810,979 A813S probably damaging Het
Cadps C A 14: 12,522,352 S604I probably damaging Het
Ces1a G T 8: 93,045,098 P24T probably damaging Het
Col4a4 T A 1: 82,455,759 M1488L unknown Het
Fndc3c1 T C X: 106,431,423 N941S probably damaging Het
Fryl T C 5: 73,086,962 Y1172C possibly damaging Het
Gm1527 T C 3: 28,895,588 probably benign Het
Hsf2 T C 10: 57,512,134 L458P probably damaging Het
Il2 T C 3: 37,123,007 T127A possibly damaging Het
Inpp5e A G 2: 26,397,934 Y617H probably damaging Het
Isoc2b G A 7: 4,850,764 S137F probably damaging Het
Map2 C T 1: 66,425,331 P241S probably damaging Het
Mfsd6 C A 1: 52,709,322 R128L probably damaging Het
Mrnip A G 11: 50,197,635 T153A probably damaging Het
Olfr1269 A G 2: 90,118,971 F209S possibly damaging Het
Olfr26 A T 9: 38,855,799 M246L probably benign Het
Pi4ka T C 16: 17,280,735 N2022S probably benign Het
Scrt2 C A 2: 152,093,640 R238S probably damaging Het
St3gal6 T A 16: 58,484,775 D108V probably benign Het
Tmem132b C T 5: 125,778,791 T529M probably damaging Het
Trappc11 T C 8: 47,501,869 probably null Het
Tspyl1 T A 10: 34,283,199 S307T possibly damaging Het
Ush2a A G 1: 188,399,785 S735G probably benign Het
Wnk2 T C 13: 49,068,192 M1186V possibly damaging Het
Other mutations in 4933427I04Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00979:4933427I04Rik APN 4 123860545 missense probably damaging 0.97
IGL02246:4933427I04Rik APN 4 123860862 missense probably damaging 0.99
PIT4494001:4933427I04Rik UTSW 4 123860905 missense probably benign
R0090:4933427I04Rik UTSW 4 123860982 missense possibly damaging 0.66
R0299:4933427I04Rik UTSW 4 123860822 missense possibly damaging 0.66
R0598:4933427I04Rik UTSW 4 123860888 missense possibly damaging 0.46
R1775:4933427I04Rik UTSW 4 123860493 missense possibly damaging 0.66
R2082:4933427I04Rik UTSW 4 123860976 missense probably benign 0.05
R4581:4933427I04Rik UTSW 4 123860353 missense possibly damaging 0.90
R4594:4933427I04Rik UTSW 4 123860538 missense possibly damaging 0.66
R4841:4933427I04Rik UTSW 4 123860377 missense probably benign 0.04
R6021:4933427I04Rik UTSW 4 123860716 missense possibly damaging 0.90
R6759:4933427I04Rik UTSW 4 123860086 start gained probably benign
R7660:4933427I04Rik UTSW 4 123860719 missense possibly damaging 0.66
Z1176:4933427I04Rik UTSW 4 123860875 missense probably damaging 0.97
Posted On2013-12-03