Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01522:Pcdha11'

89453

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Pcdha11

Ensembl Gene

ENSMUSG00000102206

Gene Name

protocadherin alpha 11

Synonyms

A830022B16Rik, Crnr7, Cnr7

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.124) question?

Stock #

IGL01522

Quality Score

Status

Chromosome

Chromosomal Location

37010712-37187657 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 37185008 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 925 (F925L)

Ref Sequence

ENSEMBL: ENSMUSP00000039888 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000007584] [ENSMUST00000047479] [ENSMUST00000047614] [ENSMUST00000070797] [ENSMUST00000115657] [ENSMUST00000115658] [ENSMUST00000115659] [ENSMUST00000115661] [ENSMUST00000115662] [ENSMUST00000192168] [ENSMUST00000192295] [ENSMUST00000192447] [ENSMUST00000193389] [ENSMUST00000193777] [ENSMUST00000192503] [ENSMUST00000194038] [ENSMUST00000192631] [ENSMUST00000192512] [ENSMUST00000195590] [ENSMUST00000193839] [ENSMUST00000194544] [ENSMUST00000194751]

AlphaFold

Q91Y19

Predicted Effect

possibly damaging
Transcript: ENSMUST00000007584
AA Change: F883L

PolyPhen 2 Score 0.922 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000007584
Gene: ENSMUSG00000103255
AA Change: F883L

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
CA	45	122	3.59e-1	SMART
CA	146	231	6.32e-22	SMART
CA	255	338	5.18e-18	SMART
CA	362	443	9.73e-23	SMART
CA	467	554	4.24e-23	SMART
CA	584	662	1.11e-8	SMART
Pfam:Cadherin_C_2	682	773	1.1e-12	PFAM
Pfam:Cadherin_tail	813	947	5.4e-58	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000047479
AA Change: F925L

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000039888
Gene: ENSMUSG00000102697
AA Change: F925L

Domain	Start	End	E-Value	Type
CA	30	145	9.8e-3	SMART
CA	169	254	2.07e-17	SMART
CA	278	362	2.86e-29	SMART
CA	386	466	4.79e-22	SMART
CA	490	576	1.44e-25	SMART
CA	606	687	3.45e-14	SMART
Pfam:Cadherin_C_2	702	809	1.2e-26	PFAM
low complexity region	810	823	N/A	INTRINSIC
Pfam:Cadherin_tail	855	989	5.8e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000047614
AA Change: F869L

PolyPhen 2 Score 0.060 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000047609
Gene: ENSMUSG00000103310
AA Change: F869L

Domain	Start	End	E-Value	Type
CA	19	131	3.78e-2	SMART
CA	155	240	3.26e-24	SMART
CA	264	348	6.37e-27	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	6.18e-25	SMART
CA	594	676	5.6e-14	SMART
low complexity region	679	696	N/A	INTRINSIC
transmembrane domain	699	721	N/A	INTRINSIC
Pfam:Cadherin_tail	799	933	5.3e-58	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000070797
AA Change: F867L

PolyPhen 2 Score 0.901 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000068828
Gene: ENSMUSG00000103442
AA Change: F867L

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC
Pfam:Cadherin_tail	797	931	5.3e-58	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000115657
AA Change: F869L

PolyPhen 2 Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000111321
Gene: ENSMUSG00000102206
AA Change: F869L

Domain	Start	End	E-Value	Type
CA	21	131	2.95e-2	SMART
CA	155	240	7.44e-19	SMART
CA	264	347	5.63e-28	SMART
CA	371	452	3.14e-26	SMART
CA	476	562	1.42e-24	SMART
CA	593	675	1.03e-12	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC
low complexity region	918	942	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000115658
AA Change: F865L

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000111322
Gene: ENSMUSG00000007440
AA Change: F865L

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
CA	46	132	6.34e-2	SMART
CA	156	241	4.65e-20	SMART
CA	265	349	1.25e-25	SMART
CA	373	454	9.22e-24	SMART
CA	478	564	4.3e-24	SMART
CA	595	678	5.07e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	795	929	5.3e-58	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000115659
AA Change: F898L

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000111323
Gene: ENSMUSG00000103770
AA Change: F898L

Domain	Start	End	E-Value	Type
low complexity region	44	51	N/A	INTRINSIC
CA	75	161	2.46e-2	SMART
CA	185	270	8.1e-20	SMART
CA	294	378	1.69e-22	SMART
CA	402	483	1.52e-24	SMART
CA	507	593	5.68e-24	SMART
CA	624	705	6.69e-12	SMART
transmembrane domain	727	749	N/A	INTRINSIC
Pfam:Cadherin_tail	828	962	5.6e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115661

SMART Domains

Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	796	930	3.9e-58	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000115662
AA Change: F867L

PolyPhen 2 Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000111326
Gene: ENSMUSG00000104148
AA Change: F867L

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC
low complexity region	916	940	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000192168
AA Change: F853L

PolyPhen 2 Score 0.963 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000142293
Gene: ENSMUSG00000103092
AA Change: F853L

Domain	Start	End	E-Value	Type
CA	21	131	2.2e-2	SMART
CA	155	240	2.05e-21	SMART
CA	264	348	8.81e-21	SMART
CA	372	453	2.01e-24	SMART
CA	477	563	1.42e-24	SMART
CA	591	673	1.63e-15	SMART
transmembrane domain	693	715	N/A	INTRINSIC
low complexity region	902	926	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000192295
AA Change: F605L

PolyPhen 2 Score 0.787 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000142103
Gene: ENSMUSG00000104252
AA Change: F605L

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	568	5.38e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000192447
AA Change: F869L

PolyPhen 2 Score 0.071 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000142270
Gene: ENSMUSG00000102206
AA Change: F869L

Domain	Start	End	E-Value	Type
CA	21	131	1.5e-4	SMART
CA	155	240	3.6e-21	SMART
CA	264	347	2.8e-30	SMART
CA	371	452	1.5e-28	SMART
CA	476	562	6.8e-27	SMART
CA	593	675	4.9e-15	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000193389
AA Change: F865L

PolyPhen 2 Score 0.901 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000141459
Gene: ENSMUSG00000103707
AA Change: F865L

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000193777
AA Change: F865L

PolyPhen 2 Score 0.834 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000141587
Gene: ENSMUSG00000103707
AA Change: F865L

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000192503
AA Change: F861L

PolyPhen 2 Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000141989
Gene: ENSMUSG00000102312
AA Change: F861L

Domain	Start	End	E-Value	Type
low complexity region	11	17	N/A	INTRINSIC
CA	42	128	3.78e-2	SMART
CA	152	237	8.94e-22	SMART
CA	261	345	3.74e-24	SMART
CA	369	450	1.09e-25	SMART
CA	474	560	1.42e-24	SMART
CA	588	670	2.96e-13	SMART
transmembrane domain	692	714	N/A	INTRINSIC
low complexity region	910	934	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000194038
AA Change: F865L

PolyPhen 2 Score 0.825 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000142159
Gene: ENSMUSG00000103800
AA Change: F865L

Domain	Start	End	E-Value	Type
CA	20	131	6.34e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	2.04e-25	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	9.88e-24	SMART
CA	594	676	8.62e-15	SMART
transmembrane domain	699	721	N/A	INTRINSIC
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000192631
AA Change: F856L

PolyPhen 2 Score 0.978 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000142156
Gene: ENSMUSG00000104318
AA Change: F856L

Domain	Start	End	E-Value	Type
CA	21	131	2.58e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	1.42e-24	SMART
CA	372	453	9.36e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	671	4.03e-6	SMART
transmembrane domain	696	718	N/A	INTRINSIC
low complexity region	905	929	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192512
AA Change: F866L

PolyPhen 2 Score 0.189 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000141408
Gene: ENSMUSG00000104252
AA Change: F866L

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
low complexity region	915	939	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000195590
AA Change: F867L

PolyPhen 2 Score 0.213 (Sensitivity: 0.92; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000141355
Gene: ENSMUSG00000104148
AA Change: F867L

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193839
AA Change: F867L

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000142308
Gene: ENSMUSG00000103442
AA Change: F867L

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000193856
AA Change: F139L

Predicted Effect

probably benign
Transcript: ENSMUST00000194544

SMART Domains

Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836

Domain	Start	End	E-Value	Type
Blast:CA	18	66	5e-20	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000193984

Predicted Effect

probably benign
Transcript: ENSMUST00000194751

SMART Domains

Protein: ENSMUSP00000142285
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
Pfam:Cadherin_2	29	112	4.5e-32	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610010F05Rik	A	G	11: 23,582,865		probably null	Het
Adamts12	T	C	15: 11,065,159		probably null	Het
Adamts3	T	C	5: 89,702,943	N579S	probably benign	Het
Akr1c19	A	G	13: 4,239,099		probably benign	Het
Ankrd39	T	A	1: 36,542,061	H69L	probably damaging	Het
Apcdd1	T	A	18: 62,952,115	M461K	possibly damaging	Het
Bpifa3	G	A	2: 154,137,582	C209Y	probably damaging	Het
Cep131	T	C	11: 120,067,163	E779G	probably benign	Het
Cep85	T	C	4: 134,152,255	Q394R	probably damaging	Het
Cep85	G	T	4: 134,152,256	Q394K	probably damaging	Het
Clcn6	T	C	4: 148,017,535	Y364C	probably benign	Het
Fetub	G	A	16: 22,929,641	M1I	probably null	Het
Greb1	T	C	12: 16,701,201	I1003V	probably damaging	Het
Hsf3	A	G	X: 96,320,594		probably benign	Het
Jcad	A	G	18: 4,673,312	N358S	probably damaging	Het
Kndc1	T	C	7: 139,913,972		probably benign	Het
Lama1	A	T	17: 67,752,774		probably benign	Het
Mark2	A	G	19: 7,281,238	V50A	probably benign	Het
Mmp7	T	C	9: 7,692,228	W35R	probably damaging	Het
Ndc80	A	G	17: 71,499,325	V578A	probably benign	Het
Nfyc	T	C	4: 120,781,524	E42G	probably damaging	Het
Olfr1164	T	C	2: 88,093,016	K307E	possibly damaging	Het
Olfr1504	A	T	19: 13,887,358	L284*	probably null	Het
Olfr344	A	G	2: 36,569,221	T208A	probably benign	Het
Olfr547	A	T	7: 102,535,184	I146F	probably damaging	Het
Olfr935	A	T	9: 38,995,100	C112S	probably benign	Het
Pdcd1	T	G	1: 94,040,846	R154S	probably benign	Het
Pepd	T	A	7: 34,924,440	D87E	probably benign	Het
Pfn4	A	G	12: 4,770,240	T30A	probably benign	Het
Pgpep1l	A	G	7: 68,237,708	M48T	possibly damaging	Het
Pla2g15	A	G	8: 106,163,116	N340S	probably benign	Het
Plcb4	A	G	2: 136,002,627	D155G	probably damaging	Het
Plg	G	A	17: 12,404,069	G499S	probably damaging	Het
Plin3	C	T	17: 56,280,799	W305*	probably null	Het
Polq	C	A	16: 37,027,903	L291I	probably damaging	Het
Sdf2l1	T	A	16: 17,132,150	H54L	probably damaging	Het
Slc38a2	C	T	15: 96,693,055	D276N	possibly damaging	Het
Syk	A	G	13: 52,643,061	T576A	probably benign	Het
Tas2r119	G	A	15: 32,178,193	V302I	probably benign	Het
Uso1	T	C	5: 92,181,419	F389L	probably damaging	Het
Wwc2	T	A	8: 47,868,633	Y482F	unknown	Het

Other mutations in Pcdha11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01843:Pcdha11	APN	18	37012833	missense	probably benign	0.28
R1165:Pcdha11	UTSW	18	37007704	intron	probably benign
R2422:Pcdha11	UTSW	18	37007272	missense	probably damaging	0.99
R2423:Pcdha11	UTSW	18	37007424	missense	possibly damaging	0.89
R2508:Pcdha11	UTSW	18	37012854	missense	possibly damaging	0.86
R3114:Pcdha11	UTSW	18	37011807	missense	probably damaging	1.00
R4173:Pcdha11	UTSW	18	37012623	missense	probably damaging	0.99
R4255:Pcdha11	UTSW	18	37012790	missense	probably benign	0.23
R4369:Pcdha11	UTSW	18	37006743	missense	possibly damaging	0.70
R4454:Pcdha11	UTSW	18	37007373	missense	probably benign	0.13
R4489:Pcdha11	UTSW	18	37006916	missense	possibly damaging	0.78
R4626:Pcdha11	UTSW	18	37006998	missense	probably damaging	1.00
R4751:Pcdha11	UTSW	18	37006944	missense	probably damaging	1.00
R4801:Pcdha11	UTSW	18	37005465	missense	probably damaging	1.00
R4802:Pcdha11	UTSW	18	37005465	missense	probably damaging	1.00
R4857:Pcdha11	UTSW	18	37011452	missense	probably benign	0.02
R4995:Pcdha11	UTSW	18	37011027	missense	probably benign	0.24
R5042:Pcdha11	UTSW	18	37011596	missense	probably damaging	1.00
R5480:Pcdha11	UTSW	18	37005882	missense	probably benign	0.04
R5495:Pcdha11	UTSW	18	37011026	missense	probably benign
R5523:Pcdha11	UTSW	18	37012386	missense	probably damaging	1.00
R5584:Pcdha11	UTSW	18	37006765	missense	probably damaging	1.00
R5682:Pcdha11	UTSW	18	37011449	missense	probably damaging	1.00
R5834:Pcdha11	UTSW	18	37012623	missense	probably damaging	0.99
R5842:Pcdha11	UTSW	18	37011284	missense	possibly damaging	0.85
R5859:Pcdha11	UTSW	18	37007283	missense	probably damaging	1.00
R6110:Pcdha11	UTSW	18	37011456	missense	probably damaging	1.00
R6135:Pcdha11	UTSW	18	37005817	missense	probably damaging	1.00
R6248:Pcdha11	UTSW	18	37005897	missense	probably benign	0.26
R6416:Pcdha11	UTSW	18	37012169	splice site	probably null
R6450:Pcdha11	UTSW	18	37013162	missense	probably damaging	1.00
R6594:Pcdha11	UTSW	18	37011182	missense	probably benign	0.04
R6631:Pcdha11	UTSW	18	37005791	missense	probably damaging	1.00
R6883:Pcdha11	UTSW	18	37011189	missense	probably damaging	1.00
R7088:Pcdha11	UTSW	18	37005417	missense	probably benign	0.00
R7129:Pcdha11	UTSW	18	37007238	missense	probably benign	0.45
R7153:Pcdha11	UTSW	18	37011225	missense	probably damaging	1.00
R7244:Pcdha11	UTSW	18	37011368	nonsense	probably null
R7295:Pcdha11	UTSW	18	37006926	missense	probably damaging	1.00
R7319:Pcdha11	UTSW	18	37013192	missense	probably benign	0.10
R7352:Pcdha11	UTSW	18	37006845	missense	probably damaging	1.00
R7516:Pcdha11	UTSW	18	37011618	missense	probably damaging	1.00
R7519:Pcdha11	UTSW	18	37006266	nonsense	probably null
R7660:Pcdha11	UTSW	18	37005851	missense	probably benign	0.17
R7677:Pcdha11	UTSW	18	37011552	missense	probably damaging	1.00
R7707:Pcdha11	UTSW	18	37011792	missense	probably benign	0.00
R7775:Pcdha11	UTSW	18	37012680	missense	possibly damaging	0.64
R7778:Pcdha11	UTSW	18	37012680	missense	possibly damaging	0.64
R7780:Pcdha11	UTSW	18	37012796	missense	probably damaging	0.97
R7916:Pcdha11	UTSW	18	37007388	missense	probably benign	0.01
R7991:Pcdha11	UTSW	18	37012856	missense	probably damaging	0.99
R8068:Pcdha11	UTSW	18	37005565	missense	probably damaging	1.00
R8220:Pcdha11	UTSW	18	37006571	missense	probably benign	0.01
R8252:Pcdha11	UTSW	18	37007537	missense	possibly damaging	0.65
R8392:Pcdha11	UTSW	18	37006159	nonsense	probably null
R8398:Pcdha11	UTSW	18	37013063	missense	possibly damaging	0.65
R8470:Pcdha11	UTSW	18	37012884	missense	probably benign	0.07
R8812:Pcdha11	UTSW	18	37007663	missense	probably benign	0.00
R8900:Pcdha11	UTSW	18	37012746	missense	probably damaging	1.00
R8968:Pcdha11	UTSW	18	37012254	missense	probably damaging	1.00
R9065:Pcdha11	UTSW	18	37006824	missense	possibly damaging	0.93
R9192:Pcdha11	UTSW	18	37007474	missense	probably benign	0.42
R9224:Pcdha11	UTSW	18	37006020	missense	probably damaging	0.99
R9228:Pcdha11	UTSW	18	37011459	missense	probably damaging	1.00
R9237:Pcdha11	UTSW	18	37012207	missense	probably damaging	1.00
R9336:Pcdha11	UTSW	18	37011461	missense	probably damaging	1.00
R9449:Pcdha11	UTSW	18	37012431	missense	probably damaging	1.00
R9475:Pcdha11	UTSW	18	37007538	missense	probably damaging	1.00
R9476:Pcdha11	UTSW	18	37006479	missense	probably benign	0.26
RF017:Pcdha11	UTSW	18	37005524	missense	possibly damaging	0.92
Z1177:Pcdha11	UTSW	18	37012923	missense	probably benign	0.43

Posted On

2013-12-03