Incidental Mutation 'IGL01535:Vmn1r177'
ID89925
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r177
Ensembl Gene ENSMUSG00000057513
Gene Namevomeronasal 1 receptor 177
SynonymsV1rd12
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.086) question?
Stock #IGL01535
Quality Score
Status
Chromosome7
Chromosomal Location23865520-23866449 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 23866340 bp
ZygosityHeterozygous
Amino Acid Change Histidine to Leucine at position 37 (H37L)
Ref Sequence ENSEMBL: ENSMUSP00000073621 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000073967]
Predicted Effect probably damaging
Transcript: ENSMUST00000073967
AA Change: H37L

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000073621
Gene: ENSMUSG00000057513
AA Change: H37L

DomainStartEndE-ValueType
Pfam:TAS2R 8 299 4.1e-13 PFAM
Pfam:V1R 41 297 5.3e-14 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000207027
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9930021J03Rik T C 19: 29,753,812 H600R possibly damaging Het
Adamts19 T A 18: 58,968,819 S654T probably benign Het
Cacnb3 A T 15: 98,639,588 Q49L probably benign Het
Dapk1 A G 13: 60,731,031 probably benign Het
Dopey2 T A 16: 93,769,958 L1091* probably null Het
Epb42 A G 2: 121,027,688 V263A probably damaging Het
Fig4 T G 10: 41,256,494 S439R probably benign Het
Gatc A T 5: 115,340,989 V54E possibly damaging Het
Hook2 T C 8: 85,002,989 L686P probably benign Het
Med12l A T 3: 59,262,259 T1615S probably damaging Het
Msr1 C T 8: 39,611,673 G320D probably benign Het
Nbeal1 T A 1: 60,217,255 F220I probably damaging Het
Olfr113 T A 17: 37,574,788 I212F possibly damaging Het
Olfr167 G A 16: 19,515,478 H53Y probably benign Het
Pcdh10 A T 3: 45,379,643 I131F probably damaging Het
Phlpp2 A G 8: 109,934,065 E784G possibly damaging Het
Prr36 A T 8: 4,214,043 probably benign Het
Ptprq G A 10: 107,699,596 S436L probably benign Het
Rock1 T A 18: 10,132,119 probably benign Het
Sash1 T G 10: 8,741,577 T522P probably damaging Het
Serpinb2 T C 1: 107,519,773 probably null Het
Supt16 T C 14: 52,177,190 K422E probably damaging Het
Syt14 T G 1: 192,986,765 D60A probably damaging Het
Tbc1d2b A C 9: 90,215,473 probably benign Het
Thsd7b T C 1: 129,678,217 I565T possibly damaging Het
Ttn A G 2: 76,734,192 Y28534H probably damaging Het
Vps13b A T 15: 35,454,957 N671Y possibly damaging Het
Other mutations in Vmn1r177
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01456:Vmn1r177 APN 7 23866328 missense possibly damaging 0.58
IGL01504:Vmn1r177 APN 7 23866410 missense probably damaging 0.98
IGL01551:Vmn1r177 APN 7 23866263 missense probably benign 0.04
IGL01647:Vmn1r177 APN 7 23866175 missense probably damaging 1.00
ANU74:Vmn1r177 UTSW 7 23866220 missense possibly damaging 0.86
R0396:Vmn1r177 UTSW 7 23865597 missense probably damaging 1.00
R0894:Vmn1r177 UTSW 7 23866050 missense probably benign 0.09
R1446:Vmn1r177 UTSW 7 23866340 missense probably damaging 1.00
R1835:Vmn1r177 UTSW 7 23865686 missense probably damaging 1.00
R1893:Vmn1r177 UTSW 7 23866148 missense probably benign 0.02
R1995:Vmn1r177 UTSW 7 23865687 missense probably damaging 1.00
R2206:Vmn1r177 UTSW 7 23866131 missense probably damaging 1.00
R3889:Vmn1r177 UTSW 7 23865864 missense possibly damaging 0.86
R4458:Vmn1r177 UTSW 7 23866220 missense possibly damaging 0.86
R4579:Vmn1r177 UTSW 7 23866347 missense possibly damaging 0.46
R5290:Vmn1r177 UTSW 7 23866073 missense probably damaging 0.99
R6128:Vmn1r177 UTSW 7 23865842 missense probably damaging 0.99
R6128:Vmn1r177 UTSW 7 23865843 missense probably damaging 1.00
R6730:Vmn1r177 UTSW 7 23865812 missense probably damaging 1.00
R6785:Vmn1r177 UTSW 7 23866137 missense probably damaging 1.00
R7100:Vmn1r177 UTSW 7 23866110 missense probably benign 0.15
R7738:Vmn1r177 UTSW 7 23866134 missense probably damaging 1.00
R8191:Vmn1r177 UTSW 7 23866311 nonsense probably null
X0020:Vmn1r177 UTSW 7 23866293 missense probably damaging 1.00
Z1177:Vmn1r177 UTSW 7 23865935 missense probably damaging 0.99
Posted On2013-12-03