Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01540:Cyp2j13'

90136

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp2j13

Ensembl Gene

ENSMUSG00000028571

Gene Name

cytochrome P450, family 2, subfamily j, polypeptide 13

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL01540

Quality Score

Status

Chromosome

Chromosomal Location

95930897-95965803 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 95956959 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000102693 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030305] [ENSMUST00000097973] [ENSMUST00000107078]

AlphaFold

Q3UNV4

Predicted Effect

probably benign
Transcript: ENSMUST00000030305

SMART Domains

Protein: ENSMUSP00000030305
Gene: ENSMUSG00000028571

Domain	Start	End	E-Value	Type
transmembrane domain	10	32	N/A	INTRINSIC
Pfam:p450	44	499	6.7e-131	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000097973

SMART Domains

Protein: ENSMUSP00000095587
Gene: ENSMUSG00000028571

Domain	Start	End	E-Value	Type
transmembrane domain	10	32	N/A	INTRINSIC
Pfam:p450	44	404	8.9e-97	PFAM
low complexity region	411	420	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000107078

SMART Domains

Protein: ENSMUSP00000102693
Gene: ENSMUSG00000028571

Domain	Start	End	E-Value	Type
transmembrane domain	10	32	N/A	INTRINSIC
Pfam:p450	44	231	2.5e-39	PFAM
Pfam:p450	218	345	8.6e-41	PFAM
low complexity region	352	361	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000120275

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 20 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrb3	A	G	1: 25,151,252 (GRCm39)		probably null	Het
Ceacam12	T	C	7: 17,805,727 (GRCm39)		probably benign	Het
Golim4	T	G	3: 75,794,047 (GRCm39)	E538A	possibly damaging	Het
Gstcd	A	T	3: 132,692,175 (GRCm39)	V580D	probably damaging	Het
Hspg2	A	G	4: 137,247,017 (GRCm39)	T1115A	probably damaging	Het
Maea	T	C	5: 33,515,910 (GRCm39)	S18P	probably benign	Het
Mertk	T	C	2: 128,625,887 (GRCm39)	L674P	probably damaging	Het
Nol8	A	T	13: 49,815,146 (GRCm39)	Q400L	probably benign	Het
Nt5el	T	C	13: 105,218,761 (GRCm39)	S32P	possibly damaging	Het
Or10a3b	G	T	7: 108,444,887 (GRCm39)	T110N	probably damaging	Het
Or6b2	A	G	1: 92,408,202 (GRCm39)	L47P	probably damaging	Het
Pycard	T	A	7: 127,592,002 (GRCm39)	D113V	probably benign	Het
S100z	G	A	13: 95,613,861 (GRCm39)	T83M	probably damaging	Het
Sacs	A	G	14: 61,429,084 (GRCm39)	D381G	possibly damaging	Het
Spata31h1	A	T	10: 82,120,016 (GRCm39)	H4331Q	possibly damaging	Het
Tbpl2	T	C	2: 23,984,985 (GRCm39)	H53R	probably benign	Het
Tlr6	T	C	5: 65,112,629 (GRCm39)	R93G	probably damaging	Het
Trabd	A	G	15: 88,968,998 (GRCm39)	E172G	probably benign	Het
Vrk3	A	G	7: 44,416,568 (GRCm39)	H277R	probably damaging	Het
Zfp512	T	C	5: 31,630,840 (GRCm39)	V338A	probably damaging	Het

Other mutations in Cyp2j13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00470:Cyp2j13	APN	4	95,950,275 (GRCm39)	missense	probably damaging	1.00
IGL01511:Cyp2j13	APN	4	95,965,552 (GRCm39)	missense	possibly damaging	0.79
IGL01923:Cyp2j13	APN	4	95,950,294 (GRCm39)	missense	probably benign	0.00
IGL03124:Cyp2j13	APN	4	95,950,159 (GRCm39)	missense	possibly damaging	0.78
IGL03389:Cyp2j13	APN	4	95,956,558 (GRCm39)	missense	probably damaging	1.00
R0671:Cyp2j13	UTSW	4	95,959,932 (GRCm39)	missense	probably damaging	0.97
R1351:Cyp2j13	UTSW	4	95,945,155 (GRCm39)	missense	probably benign	0.00
R1510:Cyp2j13	UTSW	4	95,950,209 (GRCm39)	missense	possibly damaging	0.48
R1708:Cyp2j13	UTSW	4	95,950,304 (GRCm39)	missense	probably damaging	0.99
R2327:Cyp2j13	UTSW	4	95,947,344 (GRCm39)	missense	possibly damaging	0.50
R3834:Cyp2j13	UTSW	4	95,944,794 (GRCm39)	critical splice donor site	probably null
R4643:Cyp2j13	UTSW	4	95,945,161 (GRCm39)	missense	possibly damaging	0.62
R4867:Cyp2j13	UTSW	4	95,947,235 (GRCm39)	missense	possibly damaging	0.68
R4900:Cyp2j13	UTSW	4	95,947,280 (GRCm39)	missense	probably damaging	1.00
R5175:Cyp2j13	UTSW	4	95,956,452 (GRCm39)	missense	possibly damaging	0.55
R5291:Cyp2j13	UTSW	4	95,956,566 (GRCm39)	missense	probably damaging	1.00
R5770:Cyp2j13	UTSW	4	95,965,669 (GRCm39)	missense	probably benign	0.23
R5837:Cyp2j13	UTSW	4	95,959,919 (GRCm39)	missense	probably damaging	0.98
R5912:Cyp2j13	UTSW	4	95,945,079 (GRCm39)	missense	probably damaging	1.00
R6283:Cyp2j13	UTSW	4	95,945,074 (GRCm39)	missense	possibly damaging	0.89
R6362:Cyp2j13	UTSW	4	95,959,932 (GRCm39)	missense	probably damaging	0.97
R6627:Cyp2j13	UTSW	4	95,947,343 (GRCm39)	missense	probably damaging	0.96
R7001:Cyp2j13	UTSW	4	95,945,112 (GRCm39)	missense	probably damaging	1.00
R7356:Cyp2j13	UTSW	4	95,965,655 (GRCm39)	missense	probably benign	0.23
R7620:Cyp2j13	UTSW	4	95,944,899 (GRCm39)	missense	probably benign	0.25
R8717:Cyp2j13	UTSW	4	95,933,777 (GRCm39)	missense	probably benign	0.06
R8810:Cyp2j13	UTSW	4	95,945,153 (GRCm39)	missense	probably benign	0.30
R8850:Cyp2j13	UTSW	4	95,956,428 (GRCm39)	missense	probably benign	0.09
R8981:Cyp2j13	UTSW	4	95,965,527 (GRCm39)	missense	possibly damaging	0.87
R9359:Cyp2j13	UTSW	4	95,950,170 (GRCm39)	missense	probably damaging	1.00
R9595:Cyp2j13	UTSW	4	95,933,797 (GRCm39)	nonsense	probably null

Posted On

2013-12-03