Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01542:Rergl'

90203

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Rergl

Ensembl Gene

ENSMUSG00000092164

Gene Name

RERG/RAS-like

Synonyms

EG632971

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.074) question?

Stock #

IGL01542

Quality Score

Status

Chromosome

Chromosomal Location

139470180-139478907 bp(-) (GRCm39)

Type of Mutation

critical splice acceptor site

DNA Base Change (assembly)

T to A at 139470496 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131303 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170650]

AlphaFold

B2RVE2

Predicted Effect

probably null
Transcript: ENSMUST00000170650

SMART Domains

Protein: ENSMUSP00000131303
Gene: ENSMUSG00000092164

Domain	Start	End	E-Value	Type
Pfam:Ras	5	173	7.7e-30	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arap3	G	A	18: 38,123,889 (GRCm39)	R377C	probably damaging	Het
Arhgap20	A	G	9: 51,750,187 (GRCm39)	M316V	probably benign	Het
Chd7	T	G	4: 8,859,285 (GRCm39)	N2458K	possibly damaging	Het
Clock	T	C	5: 76,379,322 (GRCm39)	E538G	possibly damaging	Het
Clpb	G	A	7: 101,436,712 (GRCm39)	V596I	probably damaging	Het
Col9a3	T	C	2: 180,251,109 (GRCm39)		probably benign	Het
D130043K22Rik	G	A	13: 25,060,020 (GRCm39)		probably null	Het
Drd4	T	C	7: 140,873,744 (GRCm39)		probably benign	Het
Fam228b	A	T	12: 4,813,055 (GRCm39)	I105N	probably damaging	Het
Gm20939	A	T	17: 95,181,721 (GRCm39)		probably benign	Het
Gm4952	A	G	19: 12,595,771 (GRCm39)	T54A	possibly damaging	Het
Hbs1l	T	C	10: 21,183,655 (GRCm39)	V132A	probably benign	Het
Kpna2	T	A	11: 106,882,027 (GRCm39)	E266D	probably benign	Het
Lars1	T	C	18: 42,347,892 (GRCm39)	E977G	probably benign	Het
Lrrn4	T	C	2: 132,721,392 (GRCm39)	T142A	probably benign	Het
Myo19	T	C	11: 84,800,372 (GRCm39)	L919P	probably damaging	Het
Nhlrc1	A	T	13: 47,167,607 (GRCm39)	F217I	probably damaging	Het
Or10q12	T	C	19: 13,745,901 (GRCm39)	F65S	probably damaging	Het
Plch1	T	C	3: 63,639,070 (GRCm39)	I468V	probably damaging	Het
Sctr	A	G	1: 119,972,499 (GRCm39)		probably benign	Het
Sdhb	T	C	4: 140,700,278 (GRCm39)	V126A	probably benign	Het
Smad3	C	T	9: 63,562,868 (GRCm39)	R214Q	probably damaging	Het
Spmip3	A	G	1: 177,570,950 (GRCm39)	T95A	possibly damaging	Het
Tdrd9	T	C	12: 112,013,423 (GRCm39)	M1219T	possibly damaging	Het
Tmem167b	A	T	3: 108,466,222 (GRCm39)	N75K	possibly damaging	Het
Vmn2r83	T	C	10: 79,314,846 (GRCm39)	S365P	probably benign	Het
Vps16	T	C	2: 130,280,314 (GRCm39)	F153L	probably damaging	Het

Other mutations in Rergl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01309:Rergl	APN	6	139,470,256 (GRCm39)	nonsense	probably null
IGL01761:Rergl	APN	6	139,478,863 (GRCm39)	missense	probably damaging	0.96
IGL02236:Rergl	APN	6	139,471,918 (GRCm39)	missense	probably benign	0.25
IGL02507:Rergl	APN	6	139,470,351 (GRCm39)	missense	probably damaging	1.00
IGL02523:Rergl	APN	6	139,473,458 (GRCm39)	splice site	probably benign
R0518:Rergl	UTSW	6	139,473,524 (GRCm39)	missense	probably damaging	1.00
R0521:Rergl	UTSW	6	139,473,524 (GRCm39)	missense	probably damaging	1.00
R2086:Rergl	UTSW	6	139,471,832 (GRCm39)	missense	probably benign
R4629:Rergl	UTSW	6	139,478,850 (GRCm39)	missense	probably damaging	1.00
R5275:Rergl	UTSW	6	139,478,819 (GRCm39)	critical splice donor site	probably null
R6364:Rergl	UTSW	6	139,477,746 (GRCm39)	missense	probably damaging	1.00
R7175:Rergl	UTSW	6	139,473,533 (GRCm39)	missense	probably benign	0.01
R8808:Rergl	UTSW	6	139,478,865 (GRCm39)	missense	probably benign	0.18
R9033:Rergl	UTSW	6	139,471,900 (GRCm39)	missense	probably damaging	1.00
R9403:Rergl	UTSW	6	139,471,852 (GRCm39)	missense	possibly damaging	0.79
R9803:Rergl	UTSW	6	139,477,761 (GRCm39)	missense	probably damaging	1.00
Z1088:Rergl	UTSW	6	139,470,424 (GRCm39)	nonsense	probably null

Posted On

2013-12-03