Incidental Mutation 'IGL01516:Vmn1r202'
ID90385
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r202
Ensembl Gene ENSMUSG00000094379
Gene Namevomeronasal 1 receptor 202
SynonymsV1ri7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.088) question?
Stock #IGL01516
Quality Score
Status
Chromosome13
Chromosomal Location22497750-22505381 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 22501462 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Serine at position 262 (T262S)
Ref Sequence ENSEMBL: ENSMUSP00000154314 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078642] [ENSMUST00000228020]
Predicted Effect possibly damaging
Transcript: ENSMUST00000078642
AA Change: T262S

PolyPhen 2 Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000077711
Gene: ENSMUSG00000094379
AA Change: T262S

DomainStartEndE-ValueType
Pfam:TAS2R 5 301 2.2e-11 PFAM
Pfam:V1R 35 300 5.6e-44 PFAM
Predicted Effect possibly damaging
Transcript: ENSMUST00000228020
AA Change: T262S

PolyPhen 2 Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 44 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921517D22Rik A G 13: 59,690,734 S95P probably benign Het
Abca6 T A 11: 110,218,217 H709L possibly damaging Het
BC051142 A G 17: 34,449,260 D168G possibly damaging Het
Bpifb1 A G 2: 154,218,252 Y455C probably benign Het
Clk1 G A 1: 58,414,404 T341I probably damaging Het
Corin A T 5: 72,454,487 Y77* probably null Het
Cps1 C T 1: 67,230,284 R1481C probably damaging Het
Cspg5 A G 9: 110,246,693 K166E probably benign Het
Dcxr A G 11: 120,725,758 probably null Het
Epha5 C A 5: 84,386,276 L65F probably damaging Het
Erbb4 T A 1: 68,328,245 K438* probably null Het
Gldc A T 19: 30,099,032 C1005S probably damaging Het
Hs3st5 C T 10: 36,833,051 T194I probably damaging Het
Hspa12a T A 19: 58,827,676 D45V probably benign Het
Il1rn C T 2: 24,349,539 T130I probably damaging Het
Klk1b22 G T 7: 44,116,308 C196F probably damaging Het
Lamp1 C T 8: 13,173,863 H332Y probably damaging Het
Limd2 T C 11: 106,159,044 T40A probably benign Het
Lztr1 G A 16: 17,522,391 probably null Het
Mbd4 T C 6: 115,849,530 T167A probably damaging Het
Mitf T A 6: 98,010,390 probably null Het
Mlph A G 1: 90,939,390 D378G probably damaging Het
Mrgprb5 A T 7: 48,168,384 L201Q probably damaging Het
Myo5b A T 18: 74,627,195 I261F probably damaging Het
Olfr1413 A T 1: 92,573,443 I91F probably benign Het
Olfr918 C T 9: 38,672,863 V207I probably benign Het
Paics T A 5: 76,956,731 L68I probably damaging Het
Pramef20 A G 4: 144,377,767 V56A probably damaging Het
Prkca C T 11: 107,961,602 V102M probably null Het
Ptpn21 G A 12: 98,715,189 T62I probably damaging Het
Ptpre A T 7: 135,664,999 E212V probably damaging Het
Rufy2 A C 10: 63,011,433 K539Q possibly damaging Het
Serpinb9d T A 13: 33,202,671 probably null Het
Smarcd1 T C 15: 99,712,213 F442L probably benign Het
Tas2r115 A G 6: 132,737,613 V125A probably damaging Het
Tmem154 C T 3: 84,684,590 H120Y probably benign Het
Tnrc6b A G 15: 80,902,622 K1321E possibly damaging Het
Trmt13 A G 3: 116,589,810 probably benign Het
Vmn1r19 T C 6: 57,404,872 F137L probably benign Het
Vmn2r57 A G 7: 41,399,946 V793A probably damaging Het
Wapl A G 14: 34,692,081 N300S probably damaging Het
Xpot T A 10: 121,590,222 probably null Het
Zfp784 G A 7: 5,036,037 probably benign Het
Zfyve26 G T 12: 79,287,851 P131Q probably benign Het
Other mutations in Vmn1r202
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01472:Vmn1r202 APN 13 22501989 missense possibly damaging 0.95
IGL01722:Vmn1r202 APN 13 22501720 missense probably benign 0.00
IGL02641:Vmn1r202 APN 13 22502104 missense probably benign 0.34
IGL02863:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL02876:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL02891:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL02943:Vmn1r202 APN 13 22502194 missense probably benign 0.01
IGL03057:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL03114:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL03114:Vmn1r202 APN 13 22501330 utr 3 prime probably benign
IGL03143:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL03159:Vmn1r202 APN 13 22501470 missense probably benign 0.00
IGL03097:Vmn1r202 UTSW 13 22501470 missense probably benign 0.00
R0611:Vmn1r202 UTSW 13 22501654 missense probably damaging 1.00
R1350:Vmn1r202 UTSW 13 22501716 missense probably benign 0.04
R1666:Vmn1r202 UTSW 13 22501370 missense possibly damaging 0.94
R1668:Vmn1r202 UTSW 13 22501370 missense possibly damaging 0.94
R1803:Vmn1r202 UTSW 13 22502143 missense probably benign 0.00
R2035:Vmn1r202 UTSW 13 22501602 missense probably damaging 0.98
R2112:Vmn1r202 UTSW 13 22501734 missense possibly damaging 0.76
R2145:Vmn1r202 UTSW 13 22501783 missense possibly damaging 0.79
R3026:Vmn1r202 UTSW 13 22501762 missense probably benign 0.03
R3808:Vmn1r202 UTSW 13 22501900 missense possibly damaging 0.83
R4714:Vmn1r202 UTSW 13 22501807 missense probably damaging 1.00
R5016:Vmn1r202 UTSW 13 22502205 missense probably damaging 1.00
R5124:Vmn1r202 UTSW 13 22501750 missense probably benign 0.01
R6136:Vmn1r202 UTSW 13 22501462 missense possibly damaging 0.90
R6365:Vmn1r202 UTSW 13 22502204 missense probably benign 0.12
R6982:Vmn1r202 UTSW 13 22501747 missense probably benign 0.02
R7293:Vmn1r202 UTSW 13 22501702 missense probably benign 0.00
R7502:Vmn1r202 UTSW 13 22502018 missense probably damaging 1.00
R7603:Vmn1r202 UTSW 13 22501620 missense probably damaging 1.00
R7672:Vmn1r202 UTSW 13 22501680 missense probably benign 0.45
R7822:Vmn1r202 UTSW 13 22502071 missense probably damaging 1.00
R8026:Vmn1r202 UTSW 13 22502144 missense possibly damaging 0.65
Posted On2013-12-09