Incidental Mutation 'IGL01516:Vmn1r202'
ID 90385
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r202
Ensembl Gene ENSMUSG00000094379
Gene Name vomeronasal 1 receptor 202
Synonyms V1ri7
Accession Numbers
Essential gene? Probably non essential (E-score: 0.087) question?
Stock # IGL01516
Quality Score
Status
Chromosome 13
Chromosomal Location 22685507-22686415 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) T to A at 22685632 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Threonine to Serine at position 262 (T262S)
Ref Sequence ENSEMBL: ENSMUSP00000154314 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078642] [ENSMUST00000228020]
AlphaFold Q8R259
Predicted Effect possibly damaging
Transcript: ENSMUST00000078642
AA Change: T262S

PolyPhen 2 Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000077711
Gene: ENSMUSG00000094379
AA Change: T262S

DomainStartEndE-ValueType
Pfam:TAS2R 5 301 2.2e-11 PFAM
Pfam:V1R 35 300 5.6e-44 PFAM
Predicted Effect possibly damaging
Transcript: ENSMUST00000228020
AA Change: T262S

PolyPhen 2 Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 44 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921517D22Rik A G 13: 59,838,548 (GRCm39) S95P probably benign Het
Abca6 T A 11: 110,109,043 (GRCm39) H709L possibly damaging Het
Bpifb1 A G 2: 154,060,172 (GRCm39) Y455C probably benign Het
Clk1 G A 1: 58,453,563 (GRCm39) T341I probably damaging Het
Corin A T 5: 72,611,830 (GRCm39) Y77* probably null Het
Cps1 C T 1: 67,269,443 (GRCm39) R1481C probably damaging Het
Cspg5 A G 9: 110,075,761 (GRCm39) K166E probably benign Het
Dcxr A G 11: 120,616,584 (GRCm39) probably null Het
Epha5 C A 5: 84,534,135 (GRCm39) L65F probably damaging Het
Erbb4 T A 1: 68,367,404 (GRCm39) K438* probably null Het
Gldc A T 19: 30,076,432 (GRCm39) C1005S probably damaging Het
Hs3st5 C T 10: 36,709,047 (GRCm39) T194I probably damaging Het
Hspa12a T A 19: 58,816,108 (GRCm39) D45V probably benign Het
Il1rn C T 2: 24,239,551 (GRCm39) T130I probably damaging Het
Klk1b22 G T 7: 43,765,732 (GRCm39) C196F probably damaging Het
Lamp1 C T 8: 13,223,863 (GRCm39) H332Y probably damaging Het
Limd2 T C 11: 106,049,870 (GRCm39) T40A probably benign Het
Lztr1 G A 16: 17,340,255 (GRCm39) probably null Het
Mbd4 T C 6: 115,826,491 (GRCm39) T167A probably damaging Het
Mitf T A 6: 97,987,351 (GRCm39) probably null Het
Mlph A G 1: 90,867,112 (GRCm39) D378G probably damaging Het
Mrgprb5 A T 7: 47,818,132 (GRCm39) L201Q probably damaging Het
Myo5b A T 18: 74,760,266 (GRCm39) I261F probably damaging Het
Or8b3b C T 9: 38,584,159 (GRCm39) V207I probably benign Het
Or9s23 A T 1: 92,501,165 (GRCm39) I91F probably benign Het
Paics T A 5: 77,104,578 (GRCm39) L68I probably damaging Het
Pramel15 A G 4: 144,104,337 (GRCm39) V56A probably damaging Het
Prkca C T 11: 107,852,428 (GRCm39) V102M probably null Het
Ptpn21 G A 12: 98,681,448 (GRCm39) T62I probably damaging Het
Ptpre A T 7: 135,266,728 (GRCm39) E212V probably damaging Het
Rufy2 A C 10: 62,847,212 (GRCm39) K539Q possibly damaging Het
Serpinb9d T A 13: 33,386,654 (GRCm39) probably null Het
Smarcd1 T C 15: 99,610,094 (GRCm39) F442L probably benign Het
Tas2r115 A G 6: 132,714,576 (GRCm39) V125A probably damaging Het
Tmem154 C T 3: 84,591,897 (GRCm39) H120Y probably benign Het
Tnrc6b A G 15: 80,786,823 (GRCm39) K1321E possibly damaging Het
Trmt13 A G 3: 116,383,459 (GRCm39) probably benign Het
Tsbp1 A G 17: 34,668,234 (GRCm39) D168G possibly damaging Het
Vmn1r19 T C 6: 57,381,857 (GRCm39) F137L probably benign Het
Vmn2r57 A G 7: 41,049,370 (GRCm39) V793A probably damaging Het
Wapl A G 14: 34,414,038 (GRCm39) N300S probably damaging Het
Xpot T A 10: 121,426,127 (GRCm39) probably null Het
Zfp784 G A 7: 5,039,036 (GRCm39) probably benign Het
Zfyve26 G T 12: 79,334,625 (GRCm39) P131Q probably benign Het
Other mutations in Vmn1r202
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01472:Vmn1r202 APN 13 22,686,159 (GRCm39) missense possibly damaging 0.95
IGL01722:Vmn1r202 APN 13 22,685,890 (GRCm39) missense probably benign 0.00
IGL02641:Vmn1r202 APN 13 22,686,274 (GRCm39) missense probably benign 0.34
IGL02863:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL02876:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL02891:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL02943:Vmn1r202 APN 13 22,686,364 (GRCm39) missense probably benign 0.01
IGL03057:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL03114:Vmn1r202 APN 13 22,685,500 (GRCm39) utr 3 prime probably benign
IGL03114:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL03143:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL03159:Vmn1r202 APN 13 22,685,640 (GRCm39) missense probably benign 0.00
IGL03097:Vmn1r202 UTSW 13 22,685,640 (GRCm39) missense probably benign 0.00
R0611:Vmn1r202 UTSW 13 22,685,824 (GRCm39) missense probably damaging 1.00
R1350:Vmn1r202 UTSW 13 22,685,886 (GRCm39) missense probably benign 0.04
R1666:Vmn1r202 UTSW 13 22,685,540 (GRCm39) missense possibly damaging 0.94
R1668:Vmn1r202 UTSW 13 22,685,540 (GRCm39) missense possibly damaging 0.94
R1803:Vmn1r202 UTSW 13 22,686,313 (GRCm39) missense probably benign 0.00
R2035:Vmn1r202 UTSW 13 22,685,772 (GRCm39) missense probably damaging 0.98
R2112:Vmn1r202 UTSW 13 22,685,904 (GRCm39) missense possibly damaging 0.76
R2145:Vmn1r202 UTSW 13 22,685,953 (GRCm39) missense possibly damaging 0.79
R3026:Vmn1r202 UTSW 13 22,685,932 (GRCm39) missense probably benign 0.03
R3808:Vmn1r202 UTSW 13 22,686,070 (GRCm39) missense possibly damaging 0.83
R4714:Vmn1r202 UTSW 13 22,685,977 (GRCm39) missense probably damaging 1.00
R5016:Vmn1r202 UTSW 13 22,686,375 (GRCm39) missense probably damaging 1.00
R5124:Vmn1r202 UTSW 13 22,685,920 (GRCm39) missense probably benign 0.01
R6136:Vmn1r202 UTSW 13 22,685,632 (GRCm39) missense possibly damaging 0.90
R6365:Vmn1r202 UTSW 13 22,686,374 (GRCm39) missense probably benign 0.12
R6982:Vmn1r202 UTSW 13 22,685,917 (GRCm39) missense probably benign 0.02
R7293:Vmn1r202 UTSW 13 22,685,872 (GRCm39) missense probably benign 0.00
R7502:Vmn1r202 UTSW 13 22,686,188 (GRCm39) missense probably damaging 1.00
R7603:Vmn1r202 UTSW 13 22,685,790 (GRCm39) missense probably damaging 1.00
R7672:Vmn1r202 UTSW 13 22,685,850 (GRCm39) missense probably benign 0.45
R7822:Vmn1r202 UTSW 13 22,686,241 (GRCm39) missense probably damaging 1.00
R7954:Vmn1r202 UTSW 13 22,685,871 (GRCm39) missense probably benign 0.01
R8026:Vmn1r202 UTSW 13 22,686,314 (GRCm39) missense possibly damaging 0.65
R8419:Vmn1r202 UTSW 13 22,685,985 (GRCm39) missense probably damaging 1.00
R9079:Vmn1r202 UTSW 13 22,685,602 (GRCm39) missense probably benign 0.00
R9194:Vmn1r202 UTSW 13 22,686,316 (GRCm39) missense possibly damaging 0.48
Posted On 2013-12-09