Incidental Mutation 'IGL01520:4430402I18Rik'
ID90498
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 4430402I18Rik
Ensembl Gene ENSMUSG00000064202
Gene NameRIKEN cDNA 4430402I18 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.142) question?
Stock #IGL01520
Quality Score
Status
Chromosome19
Chromosomal Location28893042-28967800 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 28896132 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000137486 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025875] [ENSMUST00000179171]
Predicted Effect probably benign
Transcript: ENSMUST00000025875
SMART Domains Protein: ENSMUSP00000025875
Gene: ENSMUSG00000024935

DomainStartEndE-ValueType
Pfam:SDF 20 464 2.3e-135 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000160702
Predicted Effect noncoding transcript
Transcript: ENSMUST00000161119
Predicted Effect noncoding transcript
Transcript: ENSMUST00000162189
Predicted Effect probably null
Transcript: ENSMUST00000179171
SMART Domains Protein: ENSMUSP00000137486
Gene: ENSMUSG00000064202

DomainStartEndE-ValueType
transmembrane domain 36 58 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2410089E03Rik C A 15: 8,221,911 T1889K probably damaging Het
4932438A13Rik T A 3: 36,973,260 Y2265* probably null Het
Acan T A 7: 79,084,570 H58Q probably damaging Het
Atp6v1c2 A T 12: 17,297,753 L149Q probably damaging Het
Cd40lg A G X: 57,219,788 N132D probably benign Het
Cemip G T 7: 83,948,622 T1060K probably benign Het
Ces1a G T 8: 93,045,098 P24T probably damaging Het
Ces5a A T 8: 93,519,578 S328T probably benign Het
Cfap70 A G 14: 20,420,687 C497R probably benign Het
Cndp2 T C 18: 84,668,607 K430R probably benign Het
Crlf3 T C 11: 80,060,146 D126G probably benign Het
Cxcr1 A T 1: 74,192,275 L196Q probably damaging Het
E330013P04Rik A G 19: 60,161,897 noncoding transcript Het
Erbb2 C T 11: 98,434,009 H810Y probably benign Het
Fam57a T C 11: 76,207,225 probably null Het
Fmn1 C A 2: 113,444,368 probably benign Het
Fpr3 A G 17: 17,971,063 T199A possibly damaging Het
Gcsh A G 8: 116,983,949 probably benign Het
Gm10073 T A 8: 106,573,269 I28F probably benign Het
Gucy1a2 C A 9: 3,759,561 Q456K probably damaging Het
Hgs C A 11: 120,478,348 P317T probably damaging Het
Inmt C A 6: 55,171,228 V139F probably damaging Het
Kcnma1 C A 14: 23,501,143 M460I possibly damaging Het
Map9 A T 3: 82,378,965 N359I probably damaging Het
Mavs T C 2: 131,245,343 S254P probably benign Het
Mcts1 T A X: 38,611,759 probably benign Het
Mecp2 C A X: 74,035,841 R344L possibly damaging Het
Olfr1006 T C 2: 85,674,357 T265A probably benign Het
Olfr1427 A G 19: 12,099,636 M1T probably null Het
Olfr1469 G T 19: 13,410,750 M60I probably damaging Het
Olfr392 T G 11: 73,814,786 T99P probably damaging Het
Olfr957 T C 9: 39,511,046 I225V possibly damaging Het
Olfr969 T G 9: 39,795,378 M1R probably null Het
Rasgrp1 T C 2: 117,288,663 I498V probably damaging Het
Rbbp6 T A 7: 122,985,675 S185T possibly damaging Het
Rd3 A T 1: 191,985,322 H251L possibly damaging Het
Rnf180 T A 13: 105,250,356 D148V probably damaging Het
Rnf43 C A 11: 87,664,716 A34E probably damaging Het
Rslcan18 A G 13: 67,102,108 V21A probably benign Het
Sept9 T C 11: 117,352,643 V128A probably damaging Het
Slc36a1 A G 11: 55,219,656 H103R probably benign Het
Ssh2 A G 11: 77,449,906 D628G probably damaging Het
Tmem119 A G 5: 113,795,485 F85S probably damaging Het
Tpp1 A T 7: 105,747,729 I398N probably benign Het
Ttc3 T C 16: 94,390,207 Y203H probably benign Het
Vars G T 17: 35,013,873 V898L probably benign Het
Vmn1r85 A C 7: 13,085,154 V21G probably damaging Het
Zfp521 T C 18: 13,938,988 H65R possibly damaging Het
Other mutations in 4430402I18Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00535:4430402I18Rik APN 19 28959673 intron probably benign
IGL01115:4430402I18Rik APN 19 28944442 unclassified probably null
R1104:4430402I18Rik UTSW 19 28967632 start codon destroyed probably null 0.99
R1434:4430402I18Rik UTSW 19 28927639 splice site probably benign
R1850:4430402I18Rik UTSW 19 28939171 critical splice acceptor site probably null
R1992:4430402I18Rik UTSW 19 28948624 missense probably damaging 1.00
R4042:4430402I18Rik UTSW 19 28945783 missense possibly damaging 0.83
R4043:4430402I18Rik UTSW 19 28945783 missense possibly damaging 0.83
R4044:4430402I18Rik UTSW 19 28945783 missense possibly damaging 0.83
R4845:4430402I18Rik UTSW 19 28927748 missense probably benign
R4911:4430402I18Rik UTSW 19 28897503 critical splice donor site probably benign
R4933:4430402I18Rik UTSW 19 28941775 missense possibly damaging 0.86
R5213:4430402I18Rik UTSW 19 28963564 missense probably benign 0.22
R5396:4430402I18Rik UTSW 19 28927689 missense possibly damaging 0.66
R6898:4430402I18Rik UTSW 19 28944288 missense probably benign 0.01
R7530:4430402I18Rik UTSW 19 28948721 nonsense probably null
R7883:4430402I18Rik UTSW 19 28928613 missense probably benign 0.09
R7966:4430402I18Rik UTSW 19 28928613 missense probably benign 0.09
Posted On2013-12-09