Incidental Mutation 'IGL01555:Nipal2'
ID90706
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Nipal2
Ensembl Gene ENSMUSG00000038879
Gene NameNIPA-like domain containing 2
SynonymsNpal2, 9330161F08Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL01555
Quality Score
Status
Chromosome15
Chromosomal Location34572799-34679212 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 34600118 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000153811 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000040791] [ENSMUST00000228073]
Predicted Effect probably benign
Transcript: ENSMUST00000040791
SMART Domains Protein: ENSMUSP00000038922
Gene: ENSMUSG00000038879

DomainStartEndE-ValueType
Pfam:Mg_trans_NIPA 45 332 1.5e-121 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000227222
Predicted Effect probably benign
Transcript: ENSMUST00000228073
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 18 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4833420G17Rik A G 13: 119,473,907 H372R probably benign Het
A3galt2 G A 4: 128,762,058 C73Y probably damaging Het
Arid4a C T 12: 71,061,527 probably benign Het
Ascc3 T C 10: 50,750,522 V1706A probably damaging Het
Boll A G 1: 55,305,668 probably benign Het
Camsap1 A T 2: 25,939,393 M773K possibly damaging Het
Dhx9 A T 1: 153,459,566 D929E probably damaging Het
Ect2l A G 10: 18,130,730 L775P probably damaging Het
Fat2 A T 11: 55,278,930 V3001D probably damaging Het
Gm8857 A T 5: 10,949,084 probably benign Het
Kcnh6 A T 11: 106,017,619 I354F probably damaging Het
Nemp2 T A 1: 52,641,043 V142E probably damaging Het
Otop1 A G 5: 38,302,845 Y585C probably damaging Het
Peli3 T C 19: 4,935,058 T108A probably damaging Het
Pramel6 T C 2: 87,510,785 probably benign Het
Rbfa G A 18: 80,197,800 T83I possibly damaging Het
Sstr2 A T 11: 113,625,619 I342F probably benign Het
Tll2 T A 19: 41,086,366 I920L probably benign Het
Other mutations in Nipal2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00657:Nipal2 APN 15 34600078 missense probably damaging 1.00
IGL02882:Nipal2 APN 15 34600077 missense probably damaging 1.00
IGL03230:Nipal2 APN 15 34575556 missense probably damaging 0.97
PIT4486001:Nipal2 UTSW 15 34584729 missense probably damaging 0.99
R0603:Nipal2 UTSW 15 34650398 missense probably damaging 0.97
R1255:Nipal2 UTSW 15 34584682 missense probably benign 0.30
R1530:Nipal2 UTSW 15 34625022 makesense probably null
R1673:Nipal2 UTSW 15 34648695 missense probably damaging 0.99
R1857:Nipal2 UTSW 15 34678633 missense possibly damaging 0.93
R1888:Nipal2 UTSW 15 34625021 missense possibly damaging 0.49
R1888:Nipal2 UTSW 15 34625021 missense possibly damaging 0.49
R3825:Nipal2 UTSW 15 34578706 critical splice donor site probably null
R4016:Nipal2 UTSW 15 34600061 missense possibly damaging 0.91
R4656:Nipal2 UTSW 15 34577568 critical splice donor site probably null
R6159:Nipal2 UTSW 15 34600026 missense probably damaging 1.00
R7082:Nipal2 UTSW 15 34584663 missense possibly damaging 0.95
R7263:Nipal2 UTSW 15 34578758 nonsense probably null
X0065:Nipal2 UTSW 15 34609261 nonsense probably null
Posted On2013-12-09