Incidental Mutation 'IGL01561:Fpr-rs3'
ID90837
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fpr-rs3
Ensembl Gene ENSMUSG00000060701
Gene Nameformyl peptide receptor, related sequence 3
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.224) question?
Stock #IGL01561
Quality Score
Status
Chromosome17
Chromosomal Location20623846-20624877 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 20624597 bp
ZygosityHeterozygous
Amino Acid Change Glycine to Aspartic acid at position 94 (G94D)
Ref Sequence ENSEMBL: ENSMUSP00000071179 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000071189]
Predicted Effect probably damaging
Transcript: ENSMUST00000071189
AA Change: G94D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000071179
Gene: ENSMUSG00000060701
AA Change: G94D

DomainStartEndE-ValueType
Pfam:7tm_1 43 297 1.8e-36 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aebp1 G A 11: 5,871,349 D583N probably damaging Het
Aoah T C 13: 20,905,735 probably benign Het
Aoah G T 13: 21,005,094 D496Y probably damaging Het
Cdh10 G T 15: 18,999,926 A486S possibly damaging Het
Cers2 A T 3: 95,322,161 probably null Het
Clec4a4 T A 6: 123,024,016 C229* probably null Het
Col15a1 T C 4: 47,312,118 V1311A possibly damaging Het
Fsd1 T A 17: 55,995,363 M269K probably benign Het
Golga2 A G 2: 32,296,677 M73V probably benign Het
Gusb A T 5: 129,998,086 V388E probably damaging Het
Heg1 A G 16: 33,766,668 N1267S probably benign Het
Htra4 A C 8: 25,033,571 I326S probably damaging Het
Klhl33 T C 14: 50,891,431 I780M probably benign Het
Mertk T C 2: 128,736,636 S181P probably damaging Het
Mpdz T C 4: 81,284,614 H1882R probably damaging Het
Muc13 A G 16: 33,806,041 K317E possibly damaging Het
Nek3 A G 8: 22,129,456 F440S probably damaging Het
Nrxn2 G A 19: 6,490,142 R831H probably damaging Het
Olfr1490 T C 19: 13,654,905 F159L probably benign Het
Olfr357 T A 2: 36,996,943 F44L probably benign Het
Olfr866 T C 9: 20,027,522 M139V probably benign Het
Palmd A T 3: 116,924,093 S252T probably damaging Het
Piezo2 C A 18: 63,124,614 M344I probably benign Het
Pygo1 T A 9: 72,945,288 N252K probably damaging Het
Rhobtb1 A G 10: 69,270,391 Q262R probably benign Het
Xpo1 T C 11: 23,282,706 Y409H possibly damaging Het
Zan T A 5: 137,463,866 E1017V unknown Het
Other mutations in Fpr-rs3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02230:Fpr-rs3 APN 17 20623928 missense probably damaging 1.00
IGL02503:Fpr-rs3 APN 17 20624555 missense probably damaging 1.00
IGL02809:Fpr-rs3 APN 17 20623963 missense probably damaging 0.99
IGL03212:Fpr-rs3 APN 17 20623859 missense probably benign 0.00
I2288:Fpr-rs3 UTSW 17 20624495 missense probably damaging 0.99
R0318:Fpr-rs3 UTSW 17 20624148 missense probably benign 0.02
R0565:Fpr-rs3 UTSW 17 20624021 missense probably damaging 1.00
R1005:Fpr-rs3 UTSW 17 20624084 missense probably benign 0.04
R1986:Fpr-rs3 UTSW 17 20623841 unclassified probably null
R3941:Fpr-rs3 UTSW 17 20624849 missense probably benign 0.42
R4297:Fpr-rs3 UTSW 17 20624746 missense probably damaging 1.00
R4809:Fpr-rs3 UTSW 17 20624421 missense probably benign 0.00
R4959:Fpr-rs3 UTSW 17 20623949 missense possibly damaging 0.73
R4973:Fpr-rs3 UTSW 17 20623949 missense possibly damaging 0.73
R5116:Fpr-rs3 UTSW 17 20624300 missense probably benign 0.12
R5356:Fpr-rs3 UTSW 17 20624334 missense probably damaging 0.98
R5394:Fpr-rs3 UTSW 17 20624208 missense probably benign 0.00
R5779:Fpr-rs3 UTSW 17 20624226 missense possibly damaging 0.53
R6091:Fpr-rs3 UTSW 17 20624270 missense probably benign 0.30
R6389:Fpr-rs3 UTSW 17 20623968 missense probably damaging 0.96
R6860:Fpr-rs3 UTSW 17 20624298 missense possibly damaging 0.68
R7578:Fpr-rs3 UTSW 17 20624031 missense possibly damaging 0.81
X0018:Fpr-rs3 UTSW 17 20624637 missense probably benign 0.30
Posted On2013-12-09