Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01563:Vmn1r23'

90879

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r23

Ensembl Gene

ENSMUSG00000093376

Gene Name

vomeronasal 1 receptor 23

Synonyms

V1rc24

Accession Numbers

Is this an essential gene?

Possibly non essential (E-score: 0.303) question?

Stock #

IGL01563

Quality Score

Status

Chromosome

Chromosomal Location

57925842-57926838 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 57926076 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 239 (V239A)

Ref Sequence

ENSEMBL: ENSMUSP00000135676 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000175817]

AlphaFold

Q8R2D0

Predicted Effect

possibly damaging
Transcript: ENSMUST00000175817
AA Change: V239A

PolyPhen 2 Score 0.886 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000135676
Gene: ENSMUSG00000093376
AA Change: V239A

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	3.1e-57	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alms1	A	G	6: 85,627,983	E2205G	probably damaging	Het
Arid2	G	A	15: 96,372,397	V1464I	probably damaging	Het
Axin2	A	G	11: 108,923,805	Q173R	probably damaging	Het
Best1	A	G	19: 9,986,735	F454L	probably benign	Het
CK137956	T	G	4: 127,970,635	K67T	possibly damaging	Het
Col14a1	G	A	15: 55,487,941	G1555R	unknown	Het
Csad	G	A	15: 102,187,163	S153F	probably damaging	Het
Cyp4f40	A	T	17: 32,673,956	D315V	probably damaging	Het
Galnt3	G	A	2: 66,097,757	A265V	probably damaging	Het
Gm5901	C	A	7: 105,377,515	Y163*	probably null	Het
Golga4	A	G	9: 118,527,006		probably benign	Het
Greb1l	A	G	18: 10,469,399	D138G	probably damaging	Het
Has1	A	T	17: 17,843,662		probably benign	Het
Ighv1-42	A	G	12: 114,937,184	S94P	probably damaging	Het
Katnb1	T	A	8: 95,098,159	L569Q	probably damaging	Het
Nedd1	C	T	10: 92,698,169		probably null	Het
Olfr1359	A	G	13: 21,703,073	E24G	probably benign	Het
Olfr893	T	A	9: 38,209,701	I214N	probably damaging	Het
Pdcd4	G	A	19: 53,929,121	R463H	probably benign	Het
Psmg2	G	A	18: 67,653,223	V218I	probably benign	Het
Rps19bp1	A	G	15: 80,261,331	M84T	probably benign	Het
Sass6	A	T	3: 116,605,198	D43V	probably damaging	Het
Senp6	G	A	9: 80,122,008	S551N	probably benign	Het
Sh2d2a	A	G	3: 87,852,125	E273G	probably damaging	Het
Slc16a14	T	C	1: 84,912,187		probably benign	Het
Smcr8	C	T	11: 60,783,845	R816C	possibly damaging	Het
Trappc8	A	T	18: 20,837,046	N962K	probably benign	Het
Trove2	A	G	1: 143,761,382	V364A	probably benign	Het
Trpc6	A	G	9: 8,656,603	E677G	probably damaging	Het
Ubap2	G	T	4: 41,195,998	P961T	probably damaging	Het
Vps41	T	C	13: 18,782,727		probably benign	Het
Vwf	A	T	6: 125,591,165	D341V	probably damaging	Het
Zfp618	C	T	4: 63,079,896	P45L	probably benign	Het

Other mutations in Vmn1r23

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01980:Vmn1r23	APN	6	57926490	missense	probably damaging	1.00
IGL02934:Vmn1r23	APN	6	57925929	missense	probably benign	0.26
IGL03153:Vmn1r23	APN	6	57925932	missense	probably damaging	0.98
R0410:Vmn1r23	UTSW	6	57926190	missense	probably benign	0.11
R0452:Vmn1r23	UTSW	6	57926484	missense	possibly damaging	0.90
R0590:Vmn1r23	UTSW	6	57926364	missense	probably benign	0.43
R0647:Vmn1r23	UTSW	6	57926184	missense	probably benign
R0692:Vmn1r23	UTSW	6	57926125	nonsense	probably null
R1674:Vmn1r23	UTSW	6	57926061	missense	possibly damaging	0.75
R1744:Vmn1r23	UTSW	6	57925925	missense	possibly damaging	0.81
R1774:Vmn1r23	UTSW	6	57926690	missense	probably damaging	0.97
R2101:Vmn1r23	UTSW	6	57926452	missense	possibly damaging	0.90
R2202:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R2204:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R2205:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R4282:Vmn1r23	UTSW	6	57926467	missense	probably benign	0.27
R4408:Vmn1r23	UTSW	6	57926368	missense	probably benign	0.01
R4532:Vmn1r23	UTSW	6	57925929	missense	probably benign	0.21
R4690:Vmn1r23	UTSW	6	57926025	missense	probably benign
R4700:Vmn1r23	UTSW	6	57926205	missense	probably benign	0.17
R4894:Vmn1r23	UTSW	6	57926325	missense	probably benign	0.00
R6164:Vmn1r23	UTSW	6	57926055	missense	possibly damaging	0.90
R6930:Vmn1r23	UTSW	6	57926145	missense	probably benign
R7129:Vmn1r23	UTSW	6	57926076	missense	possibly damaging	0.89
R7731:Vmn1r23	UTSW	6	57926334	missense	probably benign	0.03
R7877:Vmn1r23	UTSW	6	57926556	missense	probably benign
R8751:Vmn1r23	UTSW	6	57926467	missense	probably benign	0.27
R8809:Vmn1r23	UTSW	6	57926367	missense	probably damaging	0.97

Posted On

2013-12-09