Incidental Mutation 'IGL01563:Vmn1r23'
| ID |
90879 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r23
|
| Ensembl Gene |
ENSMUSG00000093376 |
| Gene Name |
vomeronasal 1 receptor 23 |
| Synonyms |
V1rc24 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.124)
|
| Stock # |
IGL01563
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
57902868-57903776 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 57903061 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 239
(V239A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135676
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000175817]
|
| AlphaFold |
Q8R2D0 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000175817
AA Change: V239A
PolyPhen 2
Score 0.886 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000135676
Gene: ENSMUSG00000093376
AA Change: V239A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
28 |
293 |
3.1e-57 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 33 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Alms1 |
A |
G |
6: 85,604,965 (GRCm39) |
E2205G |
probably damaging |
Het |
| Arid2 |
G |
A |
15: 96,270,278 (GRCm39) |
V1464I |
probably damaging |
Het |
| Axin2 |
A |
G |
11: 108,814,631 (GRCm39) |
Q173R |
probably damaging |
Het |
| Best1 |
A |
G |
19: 9,964,099 (GRCm39) |
F454L |
probably benign |
Het |
| CK137956 |
T |
G |
4: 127,864,428 (GRCm39) |
K67T |
possibly damaging |
Het |
| Col14a1 |
G |
A |
15: 55,351,337 (GRCm39) |
G1555R |
unknown |
Het |
| Csad |
G |
A |
15: 102,095,598 (GRCm39) |
S153F |
probably damaging |
Het |
| Cyp4f40 |
A |
T |
17: 32,892,930 (GRCm39) |
D315V |
probably damaging |
Het |
| Galnt3 |
G |
A |
2: 65,928,101 (GRCm39) |
A265V |
probably damaging |
Het |
| Gm5901 |
C |
A |
7: 105,026,722 (GRCm39) |
Y163* |
probably null |
Het |
| Golga4 |
A |
G |
9: 118,356,074 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
A |
G |
18: 10,469,399 (GRCm39) |
D138G |
probably damaging |
Het |
| Has1 |
A |
T |
17: 18,063,924 (GRCm39) |
|
probably benign |
Het |
| Ighv1-42 |
A |
G |
12: 114,900,804 (GRCm39) |
S94P |
probably damaging |
Het |
| Katnb1 |
T |
A |
8: 95,824,787 (GRCm39) |
L569Q |
probably damaging |
Het |
| Nedd1 |
C |
T |
10: 92,534,031 (GRCm39) |
|
probably null |
Het |
| Or2b2 |
A |
G |
13: 21,887,243 (GRCm39) |
E24G |
probably benign |
Het |
| Or8c15 |
T |
A |
9: 38,120,997 (GRCm39) |
I214N |
probably damaging |
Het |
| Pdcd4 |
G |
A |
19: 53,917,552 (GRCm39) |
R463H |
probably benign |
Het |
| Psmg2 |
G |
A |
18: 67,786,293 (GRCm39) |
V218I |
probably benign |
Het |
| Ro60 |
A |
G |
1: 143,637,120 (GRCm39) |
V364A |
probably benign |
Het |
| Rps19bp1 |
A |
G |
15: 80,145,532 (GRCm39) |
M84T |
probably benign |
Het |
| Sass6 |
A |
T |
3: 116,398,847 (GRCm39) |
D43V |
probably damaging |
Het |
| Senp6 |
G |
A |
9: 80,029,290 (GRCm39) |
S551N |
probably benign |
Het |
| Sh2d2a |
A |
G |
3: 87,759,432 (GRCm39) |
E273G |
probably damaging |
Het |
| Slc16a14 |
T |
C |
1: 84,889,908 (GRCm39) |
|
probably benign |
Het |
| Smcr8 |
C |
T |
11: 60,674,671 (GRCm39) |
R816C |
possibly damaging |
Het |
| Trappc8 |
A |
T |
18: 20,970,103 (GRCm39) |
N962K |
probably benign |
Het |
| Trpc6 |
A |
G |
9: 8,656,604 (GRCm39) |
E677G |
probably damaging |
Het |
| Ubap2 |
G |
T |
4: 41,195,998 (GRCm39) |
P961T |
probably damaging |
Het |
| Vps41 |
T |
C |
13: 18,966,897 (GRCm39) |
|
probably benign |
Het |
| Vwf |
A |
T |
6: 125,568,128 (GRCm39) |
D341V |
probably damaging |
Het |
| Zfp618 |
C |
T |
4: 62,998,133 (GRCm39) |
P45L |
probably benign |
Het |
|
| Other mutations in Vmn1r23 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01980:Vmn1r23
|
APN |
6 |
57,903,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02934:Vmn1r23
|
APN |
6 |
57,902,914 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL03153:Vmn1r23
|
APN |
6 |
57,902,917 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0410:Vmn1r23
|
UTSW |
6 |
57,903,175 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0452:Vmn1r23
|
UTSW |
6 |
57,903,469 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0590:Vmn1r23
|
UTSW |
6 |
57,903,349 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0647:Vmn1r23
|
UTSW |
6 |
57,903,169 (GRCm39) |
missense |
probably benign |
|
|
R0692:Vmn1r23
|
UTSW |
6 |
57,903,110 (GRCm39) |
nonsense |
probably null |
|
|
R1674:Vmn1r23
|
UTSW |
6 |
57,903,046 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1744:Vmn1r23
|
UTSW |
6 |
57,902,910 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1774:Vmn1r23
|
UTSW |
6 |
57,903,675 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2101:Vmn1r23
|
UTSW |
6 |
57,903,437 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2202:Vmn1r23
|
UTSW |
6 |
57,903,604 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2204:Vmn1r23
|
UTSW |
6 |
57,903,604 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2205:Vmn1r23
|
UTSW |
6 |
57,903,604 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4282:Vmn1r23
|
UTSW |
6 |
57,903,452 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4408:Vmn1r23
|
UTSW |
6 |
57,903,353 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4532:Vmn1r23
|
UTSW |
6 |
57,902,914 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4690:Vmn1r23
|
UTSW |
6 |
57,903,010 (GRCm39) |
missense |
probably benign |
|
|
R4700:Vmn1r23
|
UTSW |
6 |
57,903,190 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4894:Vmn1r23
|
UTSW |
6 |
57,903,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6164:Vmn1r23
|
UTSW |
6 |
57,903,040 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6930:Vmn1r23
|
UTSW |
6 |
57,903,130 (GRCm39) |
missense |
probably benign |
|
|
R7129:Vmn1r23
|
UTSW |
6 |
57,903,061 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7731:Vmn1r23
|
UTSW |
6 |
57,903,319 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7877:Vmn1r23
|
UTSW |
6 |
57,903,541 (GRCm39) |
missense |
probably benign |
|
|
R8751:Vmn1r23
|
UTSW |
6 |
57,903,452 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8809:Vmn1r23
|
UTSW |
6 |
57,903,352 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Posted On |
2013-12-09 |
Incidental Mutation