Incidental Mutation 'IGL01563:Vmn1r23'
ID90879
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r23
Ensembl Gene ENSMUSG00000093376
Gene Namevomeronasal 1 receptor 23
SynonymsV1rc24
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.081) question?
Stock #IGL01563
Quality Score
Status
Chromosome6
Chromosomal Location57925842-57926838 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 57926076 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 239 (V239A)
Ref Sequence ENSEMBL: ENSMUSP00000135676 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000175817]
Predicted Effect possibly damaging
Transcript: ENSMUST00000175817
AA Change: V239A

PolyPhen 2 Score 0.886 (Sensitivity: 0.82; Specificity: 0.94)
SMART Domains Protein: ENSMUSP00000135676
Gene: ENSMUSG00000093376
AA Change: V239A

DomainStartEndE-ValueType
Pfam:V1R 28 293 3.1e-57 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alms1 A G 6: 85,627,983 E2205G probably damaging Het
Arid2 G A 15: 96,372,397 V1464I probably damaging Het
Axin2 A G 11: 108,923,805 Q173R probably damaging Het
Best1 A G 19: 9,986,735 F454L probably benign Het
CK137956 T G 4: 127,970,635 K67T possibly damaging Het
Col14a1 G A 15: 55,487,941 G1555R unknown Het
Csad G A 15: 102,187,163 S153F probably damaging Het
Cyp4f40 A T 17: 32,673,956 D315V probably damaging Het
Galnt3 G A 2: 66,097,757 A265V probably damaging Het
Gm5901 C A 7: 105,377,515 Y163* probably null Het
Golga4 A G 9: 118,527,006 probably benign Het
Greb1l A G 18: 10,469,399 D138G probably damaging Het
Has1 A T 17: 17,843,662 probably benign Het
Ighv1-42 A G 12: 114,937,184 S94P probably damaging Het
Katnb1 T A 8: 95,098,159 L569Q probably damaging Het
Nedd1 C T 10: 92,698,169 probably null Het
Olfr1359 A G 13: 21,703,073 E24G probably benign Het
Olfr893 T A 9: 38,209,701 I214N probably damaging Het
Pdcd4 G A 19: 53,929,121 R463H probably benign Het
Psmg2 G A 18: 67,653,223 V218I probably benign Het
Rps19bp1 A G 15: 80,261,331 M84T probably benign Het
Sass6 A T 3: 116,605,198 D43V probably damaging Het
Senp6 G A 9: 80,122,008 S551N probably benign Het
Sh2d2a A G 3: 87,852,125 E273G probably damaging Het
Slc16a14 T C 1: 84,912,187 probably benign Het
Smcr8 C T 11: 60,783,845 R816C possibly damaging Het
Trappc8 A T 18: 20,837,046 N962K probably benign Het
Trove2 A G 1: 143,761,382 V364A probably benign Het
Trpc6 A G 9: 8,656,603 E677G probably damaging Het
Ubap2 G T 4: 41,195,998 P961T probably damaging Het
Vps41 T C 13: 18,782,727 probably benign Het
Vwf A T 6: 125,591,165 D341V probably damaging Het
Zfp618 C T 4: 63,079,896 P45L probably benign Het
Other mutations in Vmn1r23
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01980:Vmn1r23 APN 6 57926490 missense probably damaging 1.00
IGL02934:Vmn1r23 APN 6 57925929 missense probably benign 0.26
IGL03153:Vmn1r23 APN 6 57925932 missense probably damaging 0.98
R0410:Vmn1r23 UTSW 6 57926190 missense probably benign 0.11
R0452:Vmn1r23 UTSW 6 57926484 missense possibly damaging 0.90
R0590:Vmn1r23 UTSW 6 57926364 missense probably benign 0.43
R0647:Vmn1r23 UTSW 6 57926184 missense probably benign
R0692:Vmn1r23 UTSW 6 57926125 nonsense probably null
R1674:Vmn1r23 UTSW 6 57926061 missense possibly damaging 0.75
R1744:Vmn1r23 UTSW 6 57925925 missense possibly damaging 0.81
R1774:Vmn1r23 UTSW 6 57926690 missense probably damaging 0.97
R2101:Vmn1r23 UTSW 6 57926452 missense possibly damaging 0.90
R2202:Vmn1r23 UTSW 6 57926619 missense probably benign 0.01
R2204:Vmn1r23 UTSW 6 57926619 missense probably benign 0.01
R2205:Vmn1r23 UTSW 6 57926619 missense probably benign 0.01
R4282:Vmn1r23 UTSW 6 57926467 missense probably benign 0.27
R4408:Vmn1r23 UTSW 6 57926368 missense probably benign 0.01
R4532:Vmn1r23 UTSW 6 57925929 missense probably benign 0.21
R4690:Vmn1r23 UTSW 6 57926025 missense probably benign
R4700:Vmn1r23 UTSW 6 57926205 missense probably benign 0.17
R4894:Vmn1r23 UTSW 6 57926325 missense probably benign 0.00
R6164:Vmn1r23 UTSW 6 57926055 missense possibly damaging 0.90
R6930:Vmn1r23 UTSW 6 57926145 missense probably benign
R7129:Vmn1r23 UTSW 6 57926076 missense possibly damaging 0.89
R7731:Vmn1r23 UTSW 6 57926334 missense probably benign 0.03
R7877:Vmn1r23 UTSW 6 57926556 missense probably benign
R8751:Vmn1r23 UTSW 6 57926467 missense probably benign 0.27
R8809:Vmn1r23 UTSW 6 57926367 missense probably damaging 0.97
Posted On2013-12-09