Incidental Mutation 'IGL01563:Slc16a14'
| ID |
90909 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Slc16a14
|
| Ensembl Gene |
ENSMUSG00000026220 |
| Gene Name |
solute carrier family 16 (monocarboxylic acid transporters), member 14 |
| Synonyms |
1110004H10Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.090)
|
| Stock # |
IGL01563
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
1 |
| Chromosomal Location |
84883619-84912855 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 84889908 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000027422
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027422]
|
| AlphaFold |
Q8K1C7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000027422
|
| SMART Domains |
Protein: ENSMUSP00000027422
Gene: ENSMUSG00000026220
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:MFS_1
|
42 |
427 |
6.7e-42 |
PFAM |
|
Pfam:MFS_1
|
419 |
509 |
7.9e-10 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 33 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Alms1 |
A |
G |
6: 85,604,965 (GRCm39) |
E2205G |
probably damaging |
Het |
| Arid2 |
G |
A |
15: 96,270,278 (GRCm39) |
V1464I |
probably damaging |
Het |
| Axin2 |
A |
G |
11: 108,814,631 (GRCm39) |
Q173R |
probably damaging |
Het |
| Best1 |
A |
G |
19: 9,964,099 (GRCm39) |
F454L |
probably benign |
Het |
| CK137956 |
T |
G |
4: 127,864,428 (GRCm39) |
K67T |
possibly damaging |
Het |
| Col14a1 |
G |
A |
15: 55,351,337 (GRCm39) |
G1555R |
unknown |
Het |
| Csad |
G |
A |
15: 102,095,598 (GRCm39) |
S153F |
probably damaging |
Het |
| Cyp4f40 |
A |
T |
17: 32,892,930 (GRCm39) |
D315V |
probably damaging |
Het |
| Galnt3 |
G |
A |
2: 65,928,101 (GRCm39) |
A265V |
probably damaging |
Het |
| Gm5901 |
C |
A |
7: 105,026,722 (GRCm39) |
Y163* |
probably null |
Het |
| Golga4 |
A |
G |
9: 118,356,074 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
A |
G |
18: 10,469,399 (GRCm39) |
D138G |
probably damaging |
Het |
| Has1 |
A |
T |
17: 18,063,924 (GRCm39) |
|
probably benign |
Het |
| Ighv1-42 |
A |
G |
12: 114,900,804 (GRCm39) |
S94P |
probably damaging |
Het |
| Katnb1 |
T |
A |
8: 95,824,787 (GRCm39) |
L569Q |
probably damaging |
Het |
| Nedd1 |
C |
T |
10: 92,534,031 (GRCm39) |
|
probably null |
Het |
| Or2b2 |
A |
G |
13: 21,887,243 (GRCm39) |
E24G |
probably benign |
Het |
| Or8c15 |
T |
A |
9: 38,120,997 (GRCm39) |
I214N |
probably damaging |
Het |
| Pdcd4 |
G |
A |
19: 53,917,552 (GRCm39) |
R463H |
probably benign |
Het |
| Psmg2 |
G |
A |
18: 67,786,293 (GRCm39) |
V218I |
probably benign |
Het |
| Ro60 |
A |
G |
1: 143,637,120 (GRCm39) |
V364A |
probably benign |
Het |
| Rps19bp1 |
A |
G |
15: 80,145,532 (GRCm39) |
M84T |
probably benign |
Het |
| Sass6 |
A |
T |
3: 116,398,847 (GRCm39) |
D43V |
probably damaging |
Het |
| Senp6 |
G |
A |
9: 80,029,290 (GRCm39) |
S551N |
probably benign |
Het |
| Sh2d2a |
A |
G |
3: 87,759,432 (GRCm39) |
E273G |
probably damaging |
Het |
| Smcr8 |
C |
T |
11: 60,674,671 (GRCm39) |
R816C |
possibly damaging |
Het |
| Trappc8 |
A |
T |
18: 20,970,103 (GRCm39) |
N962K |
probably benign |
Het |
| Trpc6 |
A |
G |
9: 8,656,604 (GRCm39) |
E677G |
probably damaging |
Het |
| Ubap2 |
G |
T |
4: 41,195,998 (GRCm39) |
P961T |
probably damaging |
Het |
| Vmn1r23 |
A |
G |
6: 57,903,061 (GRCm39) |
V239A |
possibly damaging |
Het |
| Vps41 |
T |
C |
13: 18,966,897 (GRCm39) |
|
probably benign |
Het |
| Vwf |
A |
T |
6: 125,568,128 (GRCm39) |
D341V |
probably damaging |
Het |
| Zfp618 |
C |
T |
4: 62,998,133 (GRCm39) |
P45L |
probably benign |
Het |
|
| Other mutations in Slc16a14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00942:Slc16a14
|
APN |
1 |
84,900,592 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0315:Slc16a14
|
UTSW |
1 |
84,890,217 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0380:Slc16a14
|
UTSW |
1 |
84,907,251 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1469:Slc16a14
|
UTSW |
1 |
84,907,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Slc16a14
|
UTSW |
1 |
84,907,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1837:Slc16a14
|
UTSW |
1 |
84,890,120 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2149:Slc16a14
|
UTSW |
1 |
84,885,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2293:Slc16a14
|
UTSW |
1 |
84,890,564 (GRCm39) |
missense |
probably benign |
|
|
R3790:Slc16a14
|
UTSW |
1 |
84,907,001 (GRCm39) |
unclassified |
probably benign |
|
|
R4016:Slc16a14
|
UTSW |
1 |
84,890,228 (GRCm39) |
nonsense |
probably null |
|
|
R4596:Slc16a14
|
UTSW |
1 |
84,907,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4637:Slc16a14
|
UTSW |
1 |
84,885,003 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4723:Slc16a14
|
UTSW |
1 |
84,890,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5137:Slc16a14
|
UTSW |
1 |
84,890,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5262:Slc16a14
|
UTSW |
1 |
84,890,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5410:Slc16a14
|
UTSW |
1 |
84,885,145 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5927:Slc16a14
|
UTSW |
1 |
84,889,988 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5968:Slc16a14
|
UTSW |
1 |
84,890,226 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6052:Slc16a14
|
UTSW |
1 |
84,890,430 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6264:Slc16a14
|
UTSW |
1 |
84,885,130 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6290:Slc16a14
|
UTSW |
1 |
84,885,106 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7383:Slc16a14
|
UTSW |
1 |
84,890,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7390:Slc16a14
|
UTSW |
1 |
84,907,187 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7535:Slc16a14
|
UTSW |
1 |
84,890,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8326:Slc16a14
|
UTSW |
1 |
84,890,066 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8669:Slc16a14
|
UTSW |
1 |
84,900,605 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8784:Slc16a14
|
UTSW |
1 |
84,890,784 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9409:Slc16a14
|
UTSW |
1 |
84,907,116 (GRCm39) |
nonsense |
probably null |
|
|
R9469:Slc16a14
|
UTSW |
1 |
84,900,612 (GRCm39) |
missense |
probably benign |
0.05 |
|
| Posted On |
2013-12-09 |
Incidental Mutation