Incidental Mutation 'IGL01569:Trgv4'
| ID |
91102 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Trgv4
|
| Ensembl Gene |
ENSMUSG00000076745 |
| Gene Name |
T cell receptor gamma, variable 4 |
| Synonyms |
Tcrg-V4 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.048)
|
| Stock # |
IGL01569
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
19369151-19369676 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
A to G
at 19369678 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142811
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000103554]
[ENSMUST00000103555]
[ENSMUST00000198330]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103554
|
| SMART Domains |
Protein: ENSMUSP00000100335
Gene: ENSMUSG00000076745
| Domain | Start | End | E-Value | Type |
|---|
|
IGv
|
57 |
137 |
5.79e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103555
|
| SMART Domains |
Protein: ENSMUSP00000100336
Gene: ENSMUSG00000076746
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
40 |
134 |
2.94e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197661
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000198330
|
| SMART Domains |
Protein: ENSMUSP00000142811
Gene: ENSMUSG00000076746
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
IG
|
27 |
121 |
1.2e-3 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
T |
C |
17: 9,215,827 (GRCm39) |
V311A |
probably benign |
Het |
| Bdh1 |
T |
C |
16: 31,273,909 (GRCm39) |
M194T |
probably benign |
Het |
| Dnmbp |
T |
C |
19: 43,863,295 (GRCm39) |
R808G |
probably benign |
Het |
| Esco2 |
T |
C |
14: 66,063,977 (GRCm39) |
I402M |
probably benign |
Het |
| Gm5422 |
T |
C |
10: 31,125,897 (GRCm39) |
|
noncoding transcript |
Het |
| Il5ra |
C |
A |
6: 106,708,794 (GRCm39) |
M1I |
probably null |
Het |
| Kcnk4 |
T |
A |
19: 6,904,545 (GRCm39) |
I240F |
probably damaging |
Het |
| Mast4 |
T |
C |
13: 102,897,523 (GRCm39) |
E698G |
probably damaging |
Het |
| Mkln1 |
A |
G |
6: 31,405,063 (GRCm39) |
|
probably benign |
Het |
| Mypn |
C |
T |
10: 62,963,538 (GRCm39) |
G978R |
probably damaging |
Het |
| Or2m12 |
T |
C |
16: 19,105,410 (GRCm39) |
T28A |
probably benign |
Het |
| Podn |
T |
A |
4: 107,881,496 (GRCm39) |
Y6F |
probably damaging |
Het |
| Psmg2 |
G |
A |
18: 67,786,293 (GRCm39) |
V218I |
probably benign |
Het |
| Rad54l |
T |
C |
4: 115,956,195 (GRCm39) |
D544G |
probably damaging |
Het |
| Reck |
C |
A |
4: 43,925,172 (GRCm39) |
S470R |
probably benign |
Het |
| Sik3 |
A |
G |
9: 46,123,024 (GRCm39) |
H891R |
probably benign |
Het |
| Tbata |
C |
T |
10: 61,011,739 (GRCm39) |
R92* |
probably null |
Het |
| Tdrd1 |
A |
G |
19: 56,822,841 (GRCm39) |
N103S |
probably damaging |
Het |
| Timm21 |
A |
G |
18: 84,969,400 (GRCm39) |
V8A |
probably benign |
Het |
| Tnn |
A |
G |
1: 159,948,124 (GRCm39) |
V863A |
possibly damaging |
Het |
| Togaram1 |
A |
G |
12: 65,029,436 (GRCm39) |
D953G |
possibly damaging |
Het |
| Tpm1 |
T |
C |
9: 66,938,390 (GRCm39) |
|
probably null |
Het |
| Vmn1r8 |
A |
T |
6: 57,013,272 (GRCm39) |
N108Y |
possibly damaging |
Het |
| Vmn1r89 |
T |
C |
7: 12,953,432 (GRCm39) |
M56T |
probably benign |
Het |
| Ythdc2 |
A |
G |
18: 45,020,718 (GRCm39) |
E1434G |
probably benign |
Het |
|
| Other mutations in Trgv4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02821:Trgv4
|
APN |
13 |
19,369,422 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL03269:Trgv4
|
APN |
13 |
19,369,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0102:Trgv4
|
UTSW |
13 |
19,369,370 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0104:Trgv4
|
UTSW |
13 |
19,369,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4369:Trgv4
|
UTSW |
13 |
19,369,567 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4856:Trgv4
|
UTSW |
13 |
19,369,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4886:Trgv4
|
UTSW |
13 |
19,369,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Trgv4
|
UTSW |
13 |
19,369,250 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8894:Trgv4
|
UTSW |
13 |
19,369,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9031:Trgv4
|
UTSW |
13 |
19,369,169 (GRCm39) |
nonsense |
probably null |
|
|
| Posted On |
2013-12-09 |
Incidental Mutation