Incidental Mutation 'IGL01573:Lrrc72'
ID91171
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lrrc72
Ensembl Gene ENSMUSG00000020545
Gene Nameleucine rich repeat containing 72
Synonyms1700108M19Rik, 4933421E18Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.067) question?
Stock #IGL01573
Quality Score
Status
Chromosome12
Chromosomal Location36208345-36253398 bp(-) (GRCm38)
Type of Mutationsplice site (3 bp from exon)
DNA Base Change (assembly) T to A at 36212562 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000152732 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000020853] [ENSMUST00000122115] [ENSMUST00000221155]
Predicted Effect probably null
Transcript: ENSMUST00000020853
Predicted Effect probably null
Transcript: ENSMUST00000122115
SMART Domains Protein: ENSMUSP00000113517
Gene: ENSMUSG00000020545

DomainStartEndE-ValueType
Pfam:LRR_9 1 69 6.6e-10 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000152817
Predicted Effect probably null
Transcript: ENSMUST00000221155
Predicted Effect noncoding transcript
Transcript: ENSMUST00000221665
Predicted Effect noncoding transcript
Transcript: ENSMUST00000222145
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 18 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
B3gntl1 A G 11: 121,670,963 S58P probably damaging Het
Cacna1e T C 1: 154,471,367 D1018G probably benign Het
Cenpq T C 17: 40,930,045 I108V possibly damaging Het
Il7 T C 3: 7,573,843 I154M possibly damaging Het
Itga9 C A 9: 118,877,230 probably benign Het
Klhl1 A G 14: 96,201,204 probably benign Het
Mbd3 G T 10: 80,393,261 Q233K probably benign Het
Mettl5 G A 2: 69,881,315 A69V probably damaging Het
Naip1 C A 13: 100,427,382 C425F probably benign Het
Ncor2 T C 5: 125,085,026 I395V unknown Het
Nelfb A G 2: 25,203,957 L393P probably damaging Het
Olfr1242 A T 2: 89,494,201 M37K probably damaging Het
Rgs5 T C 1: 169,676,844 I21T probably benign Het
Slc22a2 G A 17: 12,605,961 V237I probably damaging Het
Slc5a1 A G 5: 33,160,865 M621V probably benign Het
Slco1a4 A G 6: 141,812,851 probably benign Het
Smg1 A G 7: 118,167,962 probably benign Het
Trim3 A G 7: 105,625,493 M15T possibly damaging Het
Other mutations in Lrrc72
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00861:Lrrc72 APN 12 36221508 missense probably benign 0.01
R1905:Lrrc72 UTSW 12 36208662 splice site probably null
R3754:Lrrc72 UTSW 12 36212568 missense probably benign 0.04
R4429:Lrrc72 UTSW 12 36208624 missense probably damaging 1.00
R6263:Lrrc72 UTSW 12 36208604 nonsense probably null
R6895:Lrrc72 UTSW 12 36209718 missense probably damaging 0.99
R7263:Lrrc72 UTSW 12 36208612 missense probably damaging 1.00
R7410:Lrrc72 UTSW 12 36222804 missense probably damaging 1.00
R7452:Lrrc72 UTSW 12 36212693 missense probably benign 0.11
R8217:Lrrc72 UTSW 12 36208677 missense probably damaging 1.00
V8831:Lrrc72 UTSW 12 36208657 missense possibly damaging 0.65
Z1177:Lrrc72 UTSW 12 36247693 critical splice acceptor site probably null
Posted On2013-12-09