Incidental Mutation 'IGL01580:Oog4'
ID91359
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Oog4
Ensembl Gene ENSMUSG00000047799
Gene Nameoogenesin 4
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.092) question?
Stock #IGL01580
Quality Score
Status
Chromosome4
Chromosomal Location143437164-143450324 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 143439112 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 155 (N155S)
Ref Sequence ENSEMBL: ENSMUSP00000073325 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000061277] [ENSMUST00000073641]
Predicted Effect probably benign
Transcript: ENSMUST00000061277
AA Change: N83S

PolyPhen 2 Score 0.161 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000052217
Gene: ENSMUSG00000047799
AA Change: N83S

DomainStartEndE-ValueType
SCOP:d1a4ya_ 195 357 6e-7 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000073641
AA Change: N155S

PolyPhen 2 Score 0.268 (Sensitivity: 0.91; Specificity: 0.88)
SMART Domains Protein: ENSMUSP00000073325
Gene: ENSMUSG00000047799
AA Change: N155S

DomainStartEndE-ValueType
SCOP:d1a4ya_ 267 429 3e-7 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca13 G A 11: 9,293,527 V1797I probably benign Het
Abi3bp A G 16: 56,675,210 E865G probably damaging Het
Ahnak A G 19: 9,002,839 T496A probably benign Het
BC030500 T C 8: 58,913,020 probably benign Het
Col6a4 A C 9: 106,068,198 Y906D probably damaging Het
Dip2c T G 13: 9,637,088 probably null Het
Frem2 A G 3: 53,655,175 I637T probably damaging Het
Guf1 T C 5: 69,565,421 probably benign Het
Htr1f G A 16: 64,925,835 R365* probably null Het
Olfr1123 A T 2: 87,418,536 I163F probably benign Het
Olfr686 T C 7: 105,203,906 I146V probably benign Het
Phactr3 C A 2: 178,269,504 probably benign Het
Pi4k2b T C 5: 52,754,661 V300A possibly damaging Het
Pik3c2g A G 6: 139,622,516 D210G probably damaging Het
Pxdn A G 12: 29,984,493 T182A probably benign Het
Scn10a A G 9: 119,627,159 V1199A probably damaging Het
Scrn2 A G 11: 97,032,130 H133R probably benign Het
Shq1 G A 6: 100,573,744 S411L possibly damaging Het
Tmcc1 A C 6: 116,042,985 V462G possibly damaging Het
Other mutations in Oog4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02207:Oog4 APN 4 143438940 missense probably benign 0.20
R0038:Oog4 UTSW 4 143438944 missense probably benign 0.20
R0038:Oog4 UTSW 4 143438944 missense probably benign 0.20
R0326:Oog4 UTSW 4 143439203 missense probably benign 0.03
R0372:Oog4 UTSW 4 143437689 missense probably damaging 1.00
R1056:Oog4 UTSW 4 143438011 missense possibly damaging 0.72
R1598:Oog4 UTSW 4 143438001 missense probably damaging 0.99
R1712:Oog4 UTSW 4 143439914 missense probably damaging 1.00
R4028:Oog4 UTSW 4 143440200 missense probably benign 0.02
R4029:Oog4 UTSW 4 143440200 missense probably benign 0.02
R4030:Oog4 UTSW 4 143440200 missense probably benign 0.02
R4705:Oog4 UTSW 4 143438875 missense probably benign 0.00
R5260:Oog4 UTSW 4 143437854 missense probably benign 0.00
R5945:Oog4 UTSW 4 143437723 missense probably benign 0.01
R6499:Oog4 UTSW 4 143437978 missense probably damaging 0.96
R6614:Oog4 UTSW 4 143437875 missense possibly damaging 0.66
R6852:Oog4 UTSW 4 143439109 missense possibly damaging 0.72
R7371:Oog4 UTSW 4 143438776 missense possibly damaging 0.47
R7375:Oog4 UTSW 4 143438974 missense possibly damaging 0.72
R7501:Oog4 UTSW 4 143437452 frame shift probably null
R7564:Oog4 UTSW 4 143437452 frame shift probably null
R7678:Oog4 UTSW 4 143437452 frame shift probably null
R7688:Oog4 UTSW 4 143437452 frame shift probably null
R7689:Oog4 UTSW 4 143437452 frame shift probably null
Z1177:Oog4 UTSW 4 143437574 missense possibly damaging 0.91
Z1177:Oog4 UTSW 4 143437575 missense probably benign 0.06
Posted On2013-12-09