Incidental Mutation 'IGL01584:Vmn1r206'
ID91461
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r206
Ensembl Gene ENSMUSG00000101578
Gene Namevomeronasal 1 receptor 206
SynonymsV1rh7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.114) question?
Stock #IGL01584
Quality Score
Status
Chromosome13
Chromosomal Location22617456-22624251 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 22620794 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Arginine at position 81 (K81R)
Ref Sequence ENSEMBL: ENSMUSP00000154713 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000187140] [ENSMUST00000227244]
Predicted Effect probably damaging
Transcript: ENSMUST00000110445
AA Change: K81R

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000106075
Gene: ENSMUSG00000071495
AA Change: K81R

DomainStartEndE-ValueType
low complexity region 3 21 N/A INTRINSIC
Pfam:V1R 32 297 6.7e-36 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000119308
Predicted Effect probably damaging
Transcript: ENSMUST00000187140
AA Change: K81R

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000139772
Gene: ENSMUSG00000101578
AA Change: K81R

DomainStartEndE-ValueType
low complexity region 3 21 N/A INTRINSIC
Pfam:V1R 32 297 6.7e-36 PFAM
Predicted Effect probably damaging
Transcript: ENSMUST00000227244
AA Change: K81R

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 A G 11: 110,304,923 V570A probably damaging Het
Abcb1a T C 5: 8,698,637 S323P possibly damaging Het
Adcy8 C T 15: 64,815,321 D445N probably damaging Het
Cdc14a A T 3: 116,392,825 Y102* probably null Het
Cubn A G 2: 13,308,661 probably benign Het
Dcaf7 T C 11: 106,053,827 S279P probably benign Het
Dock10 T C 1: 80,533,850 Q1514R probably damaging Het
Dtx2 G A 5: 136,026,566 S369N possibly damaging Het
Dusp11 A G 6: 85,953,394 F136S probably damaging Het
Fbxo32 T C 15: 58,184,236 D227G probably damaging Het
Flg2 T A 3: 93,213,466 V1215E unknown Het
Flg2 A T 3: 93,215,470 D1649V unknown Het
Gabbr2 T C 4: 46,674,524 K821R probably damaging Het
Gga2 T C 7: 121,991,538 T516A probably benign Het
Gm12394 A C 4: 42,794,014 S39R probably damaging Het
Gm15446 T A 5: 109,940,802 *64K probably null Het
Gm5900 T C 7: 104,950,154 noncoding transcript Het
Il17rb A G 14: 30,003,680 F121S probably damaging Het
Ip6k3 C A 17: 27,151,060 R128L probably benign Het
Kmt2d A T 15: 98,856,369 probably benign Het
Lrrn4 A G 2: 132,878,076 L268P probably damaging Het
Mthfd1l C A 10: 4,016,738 S332R probably damaging Het
Olfr101 C T 17: 37,299,738 R228H probably benign Het
Olfr1102 G A 2: 87,002,151 V61I probably benign Het
Pdzd2 T C 15: 12,592,483 E25G probably damaging Het
Prima1 A T 12: 103,202,788 probably null Het
Rbm26 A G 14: 105,131,532 V737A probably damaging Het
Ryr2 C T 13: 11,601,758 probably null Het
Sema5b G T 16: 35,645,423 C114F probably damaging Het
Speg T C 1: 75,430,937 V3196A probably damaging Het
Svs3b T C 2: 164,256,023 Y126C probably benign Het
Tmem171 T C 13: 98,692,175 probably null Het
Tnrc6b T A 15: 80,879,682 W462R probably benign Het
Trdmt1 T C 2: 13,519,928 R239G probably benign Het
Usp5 A T 6: 124,819,387 V583E probably damaging Het
Utrn A G 10: 12,726,367 V639A probably benign Het
Vwa3a A G 7: 120,783,974 I599M probably benign Het
Other mutations in Vmn1r206
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02016:Vmn1r206 APN 13 22620164 missense probably damaging 0.99
IGL02754:Vmn1r206 APN 13 22620890 nonsense probably null
R0317:Vmn1r206 UTSW 13 22620960 missense possibly damaging 0.86
R0570:Vmn1r206 UTSW 13 22620413 missense probably damaging 1.00
R1056:Vmn1r206 UTSW 13 22620614 missense probably benign 0.10
R1497:Vmn1r206 UTSW 13 22620990 missense probably benign 0.23
R2018:Vmn1r206 UTSW 13 22620188 missense probably damaging 1.00
R2128:Vmn1r206 UTSW 13 22620612 missense probably benign 0.09
R2129:Vmn1r206 UTSW 13 22620612 missense probably benign 0.09
R5159:Vmn1r206 UTSW 13 22620605 missense probably damaging 1.00
R7692:Vmn1r206 UTSW 13 22620657 missense probably damaging 1.00
R7763:Vmn1r206 UTSW 13 22620669 missense possibly damaging 0.74
R7910:Vmn1r206 UTSW 13 22620301 nonsense probably null
R7991:Vmn1r206 UTSW 13 22620301 nonsense probably null
X0026:Vmn1r206 UTSW 13 22620554 missense possibly damaging 0.53
Posted On2013-12-09