Incidental Mutation 'IGL01584:Gm15446'
ID91495
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm15446
Ensembl Gene ENSMUSG00000090015
Gene Namepredicted gene 15446
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.058) question?
Stock #IGL01584
Quality Score
Status
Chromosome5
Chromosomal Location109923400-109943936 bp(+) (GRCm38)
Type of Mutationmakesense
DNA Base Change (assembly) T to A at 109940802 bp
ZygosityHeterozygous
Amino Acid Change Stop codon to Lysine at position 64 (*64K)
Ref Sequence ENSEMBL: ENSMUSP00000127438 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000112544] [ENSMUST00000170826]
Predicted Effect probably null
Transcript: ENSMUST00000112544
SMART Domains Protein: ENSMUSP00000108163
Gene: ENSMUSG00000090015

DomainStartEndE-ValueType
KRAB 4 60 1.74e-14 SMART
ZnF_C2H2 103 125 1.1e-2 SMART
ZnF_C2H2 131 153 1.67e-2 SMART
ZnF_C2H2 159 181 4.87e-4 SMART
ZnF_C2H2 187 209 3.39e-3 SMART
ZnF_C2H2 215 237 1.76e-1 SMART
ZnF_C2H2 243 265 1.3e-4 SMART
ZnF_C2H2 271 293 1.1e-2 SMART
ZnF_C2H2 299 321 2.27e-4 SMART
ZnF_C2H2 327 349 6.99e-5 SMART
ZnF_C2H2 355 377 5.21e-4 SMART
ZnF_C2H2 383 405 9.73e-4 SMART
ZnF_C2H2 411 433 3.39e-3 SMART
ZnF_C2H2 439 461 1.58e-3 SMART
ZnF_C2H2 467 489 5.14e-3 SMART
ZnF_C2H2 495 517 2.61e-4 SMART
ZnF_C2H2 523 545 3.21e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000146564
Predicted Effect probably null
Transcript: ENSMUST00000170826
AA Change: *64K
SMART Domains Protein: ENSMUSP00000127438
Gene: ENSMUSG00000090015
AA Change: *64K

DomainStartEndE-ValueType
KRAB 3 59 1.74e-14 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 A G 11: 110,304,923 V570A probably damaging Het
Abcb1a T C 5: 8,698,637 S323P possibly damaging Het
Adcy8 C T 15: 64,815,321 D445N probably damaging Het
Cdc14a A T 3: 116,392,825 Y102* probably null Het
Cubn A G 2: 13,308,661 probably benign Het
Dcaf7 T C 11: 106,053,827 S279P probably benign Het
Dock10 T C 1: 80,533,850 Q1514R probably damaging Het
Dtx2 G A 5: 136,026,566 S369N possibly damaging Het
Dusp11 A G 6: 85,953,394 F136S probably damaging Het
Fbxo32 T C 15: 58,184,236 D227G probably damaging Het
Flg2 T A 3: 93,213,466 V1215E unknown Het
Flg2 A T 3: 93,215,470 D1649V unknown Het
Gabbr2 T C 4: 46,674,524 K821R probably damaging Het
Gga2 T C 7: 121,991,538 T516A probably benign Het
Gm12394 A C 4: 42,794,014 S39R probably damaging Het
Gm5900 T C 7: 104,950,154 noncoding transcript Het
Il17rb A G 14: 30,003,680 F121S probably damaging Het
Ip6k3 C A 17: 27,151,060 R128L probably benign Het
Kmt2d A T 15: 98,856,369 probably benign Het
Lrrn4 A G 2: 132,878,076 L268P probably damaging Het
Mthfd1l C A 10: 4,016,738 S332R probably damaging Het
Olfr101 C T 17: 37,299,738 R228H probably benign Het
Olfr1102 G A 2: 87,002,151 V61I probably benign Het
Pdzd2 T C 15: 12,592,483 E25G probably damaging Het
Prima1 A T 12: 103,202,788 probably null Het
Rbm26 A G 14: 105,131,532 V737A probably damaging Het
Ryr2 C T 13: 11,601,758 probably null Het
Sema5b G T 16: 35,645,423 C114F probably damaging Het
Speg T C 1: 75,430,937 V3196A probably damaging Het
Svs3b T C 2: 164,256,023 Y126C probably benign Het
Tmem171 T C 13: 98,692,175 probably null Het
Tnrc6b T A 15: 80,879,682 W462R probably benign Het
Trdmt1 T C 2: 13,519,928 R239G probably benign Het
Usp5 A T 6: 124,819,387 V583E probably damaging Het
Utrn A G 10: 12,726,367 V639A probably benign Het
Vmn1r206 T C 13: 22,620,794 K81R probably damaging Het
Vwa3a A G 7: 120,783,974 I599M probably benign Het
Other mutations in Gm15446
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0278:Gm15446 UTSW 5 109943415 missense probably benign 0.14
R0606:Gm15446 UTSW 5 109943481 missense probably benign
R1608:Gm15446 UTSW 5 109942457 missense probably damaging 1.00
R1874:Gm15446 UTSW 5 109942553 missense probably damaging 0.99
R1892:Gm15446 UTSW 5 109943387 missense probably damaging 1.00
R2000:Gm15446 UTSW 5 109942811 missense possibly damaging 0.67
R2059:Gm15446 UTSW 5 109942496 missense probably damaging 1.00
R3083:Gm15446 UTSW 5 109943292 missense possibly damaging 0.48
R3883:Gm15446 UTSW 5 109940447 missense probably damaging 0.98
R4086:Gm15446 UTSW 5 109943255 missense probably benign 0.02
R4095:Gm15446 UTSW 5 109940724 intron probably null
R4459:Gm15446 UTSW 5 109943241 missense probably benign 0.03
R4721:Gm15446 UTSW 5 109943000 missense probably damaging 1.00
R4735:Gm15446 UTSW 5 109942952 missense probably damaging 1.00
R5229:Gm15446 UTSW 5 109943170 missense probably damaging 1.00
R5502:Gm15446 UTSW 5 109940498 nonsense probably null
R6116:Gm15446 UTSW 5 109943036 missense probably damaging 1.00
R6166:Gm15446 UTSW 5 109942780 nonsense probably null
R6322:Gm15446 UTSW 5 109943517 missense probably damaging 1.00
R7871:Gm15446 UTSW 5 109943299 nonsense probably null
R7954:Gm15446 UTSW 5 109943299 nonsense probably null
R8045:Gm15446 UTSW 5 109940528 missense probably damaging 1.00
R8069:Gm15446 UTSW 5 109940440 nonsense probably null
Posted On2013-12-09