Incidental Mutation 'IGL01588:Znhit6'
ID91517
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Znhit6
Ensembl Gene ENSMUSG00000074182
Gene Namezinc finger, HIT type 6
Synonyms2410019A14Rik
Accession Numbers
Is this an essential gene? Essential (E-score: 1.000) question?
Stock #IGL01588
Quality Score
Status
Chromosome3
Chromosomal Location145576205-145604795 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 145596207 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000143306 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000098534] [ENSMUST00000196413] [ENSMUST00000197604] [ENSMUST00000199033]
Predicted Effect probably benign
Transcript: ENSMUST00000098534
SMART Domains Protein: ENSMUSP00000096136
Gene: ENSMUSG00000074182

DomainStartEndE-ValueType
low complexity region 19 34 N/A INTRINSIC
low complexity region 118 150 N/A INTRINSIC
Pfam:zf-HIT 208 237 4.1e-10 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000196413
SMART Domains Protein: ENSMUSP00000143376
Gene: ENSMUSG00000074182

DomainStartEndE-ValueType
Pfam:zf-HIT 64 93 3.4e-7 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000197474
Predicted Effect probably benign
Transcript: ENSMUST00000197604
SMART Domains Protein: ENSMUSP00000143484
Gene: ENSMUSG00000074182

DomainStartEndE-ValueType
Pfam:zf-HIT 40 69 2.4e-7 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000199033
SMART Domains Protein: ENSMUSP00000143306
Gene: ENSMUSG00000074182

DomainStartEndE-ValueType
Pfam:zf-HIT 40 69 4.7e-7 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aspm T A 1: 139,478,162 S1596T probably benign Het
Atp10b G A 11: 43,172,721 R161H probably benign Het
Csn2 T C 5: 87,694,649 H165R probably benign Het
Dido1 A G 2: 180,688,875 V260A probably benign Het
Ece1 C T 4: 137,957,206 probably benign Het
Garem1 T G 18: 21,129,797 R653S probably damaging Het
Gpatch2 A T 1: 187,230,794 S261C probably damaging Het
Ing4 A G 6: 125,043,986 N24D possibly damaging Het
Klhdc7a A T 4: 139,966,946 V230D probably damaging Het
Ly96 G A 1: 16,709,454 V116I probably benign Het
Myom1 C T 17: 71,117,437 T1427M possibly damaging Het
Nedd1 C A 10: 92,686,262 V638L probably benign Het
Olfr1161 T C 2: 88,025,073 V117A probably benign Het
Olfr653 C T 7: 104,579,943 S99F probably damaging Het
Olfr948 G A 9: 39,318,832 Q261* probably null Het
Pbx2 T C 17: 34,595,618 probably benign Het
Phlpp1 A T 1: 106,380,389 H1132L probably damaging Het
Plpp5 T A 8: 25,724,168 H237Q probably damaging Het
Stard13 C T 5: 151,045,237 R856H probably damaging Het
Sult1e1 T C 5: 87,576,243 K285R probably benign Het
Ubxn8 C T 8: 33,621,559 V269M probably damaging Het
Usp29 A T 7: 6,962,611 K484N probably benign Het
Whrn C T 4: 63,472,778 V80M probably damaging Het
Other mutations in Znhit6
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00160:Znhit6 APN 3 145578160 missense probably damaging 1.00
IGL00969:Znhit6 APN 3 145594596 splice site probably benign
IGL01911:Znhit6 APN 3 145578098 splice site probably benign
IGL02118:Znhit6 APN 3 145578104 missense probably damaging 1.00
R1066:Znhit6 UTSW 3 145578497 missense probably damaging 1.00
R1115:Znhit6 UTSW 3 145594685 splice site probably null
R2278:Znhit6 UTSW 3 145576236 unclassified probably benign
R2391:Znhit6 UTSW 3 145594658 missense probably damaging 1.00
R2656:Znhit6 UTSW 3 145578169 critical splice donor site probably null
R2877:Znhit6 UTSW 3 145576654 missense probably benign 0.31
R3825:Znhit6 UTSW 3 145578344 missense probably benign 0.17
R4636:Znhit6 UTSW 3 145600578 splice site silent
R4636:Znhit6 UTSW 3 145600579 missense probably null 0.11
R5295:Znhit6 UTSW 3 145600493 missense probably benign 0.41
R5964:Znhit6 UTSW 3 145576933 missense possibly damaging 0.66
R5965:Znhit6 UTSW 3 145578348 missense possibly damaging 0.80
R6537:Znhit6 UTSW 3 145594619 missense probably benign 0.32
X0065:Znhit6 UTSW 3 145578486 missense probably benign
Posted On2013-12-09