Incidental Mutation 'IGL01590:Gpatch3'
ID91582
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gpatch3
Ensembl Gene ENSMUSG00000028850
Gene NameG patch domain containing 3
SynonymsGpatc3, D930035B09Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.097) question?
Stock #IGL01590
Quality Score
Status
Chromosome4
Chromosomal Location133574745-133584243 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to G at 133580717 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000101519 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000030661] [ENSMUST00000030662] [ENSMUST00000105899]
Predicted Effect probably benign
Transcript: ENSMUST00000030661
SMART Domains Protein: ENSMUSP00000030661
Gene: ENSMUSG00000028848

DomainStartEndE-ValueType
Pfam:ATP_bind_1 14 261 6.6e-81 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000030662
SMART Domains Protein: ENSMUSP00000030662
Gene: ENSMUSG00000028850

DomainStartEndE-ValueType
low complexity region 83 97 N/A INTRINSIC
low complexity region 274 305 N/A INTRINSIC
G_patch 409 457 1.3e-7 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000105899
SMART Domains Protein: ENSMUSP00000101519
Gene: ENSMUSG00000028848

DomainStartEndE-ValueType
Pfam:ATP_bind_1 14 117 9.2e-42 PFAM
Pfam:ATP_bind_1 115 238 4.3e-28 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000148909
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154648
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921504E06Rik T A 2: 19,477,779 probably benign Het
Adgrb2 T G 4: 130,013,813 probably benign Het
Apcs C T 1: 172,894,467 G104D probably damaging Het
Atp10b G A 11: 43,172,721 R161H probably benign Het
Cep250 A T 2: 155,992,317 Q2054L possibly damaging Het
Dennd6a T G 14: 26,619,352 V207G probably benign Het
Ehbp1 C A 11: 22,095,611 D688Y possibly damaging Het
Fam83a C A 15: 58,009,777 S334Y probably damaging Het
Fam83e T A 7: 45,723,936 F242Y probably null Het
Fnip1 A T 11: 54,493,300 D341V probably damaging Het
Gm17359 A C 3: 79,449,340 N150T probably damaging Het
Gm5286 G A 3: 94,198,367 probably benign Het
Gpc2 C A 5: 138,274,378 V558F probably damaging Het
H2-M10.6 A G 17: 36,812,749 N112D probably benign Het
Hs6st1 A T 1: 36,103,704 D240V probably damaging Het
Inpp5f T A 7: 128,664,307 probably null Het
Itga8 G T 2: 12,160,333 H822N probably damaging Het
Kif20b T A 19: 34,954,726 N1263K possibly damaging Het
Krt28 A G 11: 99,374,394 probably null Het
Muc5ac A T 7: 141,798,893 M706L probably benign Het
Olfr340 A T 2: 36,452,992 M136L probably benign Het
Olfr651 A C 7: 104,553,575 I219L probably benign Het
Prox2 A G 12: 85,088,071 W479R probably damaging Het
Rps19 A T 7: 24,888,456 D152V probably damaging Het
Slc20a1 G A 2: 129,209,226 probably benign Het
Slc7a2 C T 8: 40,914,100 P564S probably damaging Het
Slco1a5 C A 6: 142,250,319 M319I probably benign Het
Tanc1 A G 2: 59,785,473 T275A probably benign Het
Tenm3 A G 8: 48,228,802 S2598P probably damaging Het
Tiparp G A 3: 65,531,976 E56K probably benign Het
Trpm5 G A 7: 143,082,734 R489C probably damaging Het
Vmn2r84 C A 10: 130,386,095 G752V probably damaging Het
Wnt5b T A 6: 119,440,554 T130S possibly damaging Het
Other mutations in Gpatch3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02876:Gpatch3 APN 4 133580684 missense probably damaging 1.00
IGL03181:Gpatch3 APN 4 133578122 missense probably damaging 1.00
ANU23:Gpatch3 UTSW 4 133578302 small deletion probably benign
PIT4585001:Gpatch3 UTSW 4 133583086 missense probably damaging 0.99
R0358:Gpatch3 UTSW 4 133577904 splice site probably null
R0383:Gpatch3 UTSW 4 133578146 missense probably damaging 1.00
R1706:Gpatch3 UTSW 4 133575173 nonsense probably null
R2269:Gpatch3 UTSW 4 133583807 missense possibly damaging 0.83
R3788:Gpatch3 UTSW 4 133575168 missense possibly damaging 0.93
R4030:Gpatch3 UTSW 4 133578147 missense possibly damaging 0.94
R4334:Gpatch3 UTSW 4 133582481 missense probably damaging 1.00
R4718:Gpatch3 UTSW 4 133582544 missense probably benign 0.37
R5036:Gpatch3 UTSW 4 133578150 missense probably damaging 1.00
R6032:Gpatch3 UTSW 4 133578306 missense probably benign 0.06
R6032:Gpatch3 UTSW 4 133578306 missense probably benign 0.06
R6572:Gpatch3 UTSW 4 133574880 missense probably damaging 1.00
R6923:Gpatch3 UTSW 4 133582525 missense probably damaging 1.00
R7106:Gpatch3 UTSW 4 133578203 missense probably benign 0.05
R7572:Gpatch3 UTSW 4 133574806 missense probably benign 0.01
R7737:Gpatch3 UTSW 4 133575096 missense probably benign 0.01
RF025:Gpatch3 UTSW 4 133578310 frame shift probably null
Posted On2013-12-09