Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01598:Iqcf6'

91750

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Iqcf6

Ensembl Gene

ENSMUSG00000091129

Gene Name

IQ motif containing F6

Synonyms

100041096

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.140) question?

Stock #

IGL01598

Quality Score

Status

Chromosome

Chromosomal Location

106503800-106504874 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 106504707 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 124 (T124A)

Ref Sequence

ENSEMBL: ENSMUSP00000131823 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171091]

AlphaFold

G3UWF2

Predicted Effect

probably benign
Transcript: ENSMUST00000171091
AA Change: T124A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000131823
Gene: ENSMUSG00000091129
AA Change: T124A

Domain	Start	End	E-Value	Type
IQ	35	57	2.06e-3	SMART
IQ	91	113	8.13e-2	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410124H12Rik	T	A	16: 92,275,817 (GRCm39)		noncoding transcript	Het
Apc2	T	A	10: 80,148,882 (GRCm39)	L1283Q	probably damaging	Het
Apol6	G	A	15: 76,934,916 (GRCm39)	A62T	probably damaging	Het
AU018091	A	T	7: 3,212,110 (GRCm39)	I204N	possibly damaging	Het
B4galnt4	G	T	7: 140,650,428 (GRCm39)	R765L	probably benign	Het
Brca1	T	C	11: 101,415,156 (GRCm39)	T993A	probably benign	Het
Cadps	C	T	14: 12,522,202 (GRCm38)		probably null	Het
Ccdc177	A	G	12: 80,805,519 (GRCm39)	S252P	unknown	Het
Cdc73	A	G	1: 143,575,017 (GRCm39)	S59P	probably damaging	Het
Cep63	G	T	9: 102,467,657 (GRCm39)	Q570K	possibly damaging	Het
Ces1c	A	T	8: 93,845,041 (GRCm39)	I120K	probably benign	Het
Cpeb1	T	C	7: 81,011,549 (GRCm39)	M131V	probably benign	Het
Dync1h1	G	A	12: 110,624,562 (GRCm39)	V3701I	probably damaging	Het
Fxr1	T	C	3: 34,118,381 (GRCm39)	S535P	possibly damaging	Het
Gldc	A	T	19: 30,111,156 (GRCm39)	V540D	probably damaging	Het
Itih4	A	G	14: 30,609,774 (GRCm39)	I35V	possibly damaging	Het
Kmt2c	T	C	5: 25,478,664 (GRCm39)	*1525W	probably null	Het
Kmt2c	A	T	5: 25,559,769 (GRCm39)	V963E	probably damaging	Het
Lmnb2	T	C	10: 80,742,999 (GRCm39)	S202G	probably benign	Het
Med23	T	G	10: 24,779,696 (GRCm39)	S924R	probably benign	Het
Or5b102	T	C	19: 13,041,513 (GRCm39)	V246A	probably damaging	Het
Pcif1	T	C	2: 164,728,531 (GRCm39)	F263L	possibly damaging	Het
Pon2	A	T	6: 5,272,331 (GRCm39)	L163H	probably damaging	Het
Scn1a	C	T	2: 66,132,829 (GRCm39)	V165M	possibly damaging	Het
Sema6d	C	A	2: 124,507,018 (GRCm39)	P961Q	probably damaging	Het
Snx27	A	G	3: 94,469,150 (GRCm39)	Y64H	probably damaging	Het
Srsf11	C	T	3: 157,717,672 (GRCm39)		probably benign	Het
Taok1	A	G	11: 77,462,510 (GRCm39)	V193A	probably damaging	Het
Tut4	A	G	4: 108,408,017 (GRCm39)		probably benign	Het
Vps13d	T	C	4: 144,743,471 (GRCm39)	T4137A	probably benign	Het
Zbtb26	T	C	2: 37,326,283 (GRCm39)	Y251C	probably damaging	Het

Other mutations in Iqcf6

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02006:Iqcf6	APN	9	106,504,510 (GRCm39)	missense	probably benign	0.13
IGL02519:Iqcf6	APN	9	106,504,479 (GRCm39)	missense	probably damaging	1.00
R0925:Iqcf6	UTSW	9	106,504,500 (GRCm39)	missense	probably benign	0.00
R1493:Iqcf6	UTSW	9	106,504,641 (GRCm39)	missense	probably benign	0.00
R4686:Iqcf6	UTSW	9	106,504,543 (GRCm39)	missense	probably damaging	1.00
R6590:Iqcf6	UTSW	9	106,504,501 (GRCm39)	missense	possibly damaging	0.83
R6690:Iqcf6	UTSW	9	106,504,501 (GRCm39)	missense	possibly damaging	0.83
R7489:Iqcf6	UTSW	9	106,504,656 (GRCm39)	missense	probably benign	0.25
R8847:Iqcf6	UTSW	9	106,504,650 (GRCm39)	missense	probably damaging	1.00
R8867:Iqcf6	UTSW	9	106,504,698 (GRCm39)	missense	possibly damaging	0.73

Posted On

2013-12-09