Incidental Mutation 'IGL01619:Prss29'
ID92538
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prss29
Ensembl Gene ENSMUSG00000034039
Gene Nameprotease, serine 29
SynonymsIsp2, mISP-2
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.059) question?
Stock #IGL01619
Quality Score
Status
Chromosome17
Chromosomal Location25318654-25322681 bp(+) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) T to C at 25321139 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000024993 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000024993]
Predicted Effect probably null
Transcript: ENSMUST00000024993
SMART Domains Protein: ENSMUSP00000024993
Gene: ENSMUSG00000034039

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
Tryp_SPc 30 271 7.11e-89 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ankrd46 T C 15: 36,485,967 T47A possibly damaging Het
Asxl3 T G 18: 22,523,328 V1465G probably damaging Het
Celsr3 A G 9: 108,837,404 H1995R probably benign Het
Celsr3 A T 9: 108,834,557 D1657V probably damaging Het
Cntn6 G A 6: 104,728,374 probably benign Het
Def6 C T 17: 28,207,864 L8F probably damaging Het
Dnah9 T A 11: 65,831,615 K1940* probably null Het
Dock10 A G 1: 80,634,298 probably benign Het
Fam166b G A 4: 43,427,814 T170I possibly damaging Het
Fam72a A G 1: 131,533,912 I112V probably benign Het
Fgl1 A T 8: 41,196,971 W258R probably damaging Het
Ints6l G T X: 56,496,744 probably benign Het
Lifr A T 15: 7,191,162 N1091I probably damaging Het
Mga T C 2: 119,931,828 I1100T possibly damaging Het
Mrpl40 T A 16: 18,872,544 M139L probably benign Het
Myom1 T C 17: 71,044,476 probably benign Het
Olfr164 T A 16: 19,286,159 T195S probably damaging Het
Pcdhb5 T C 18: 37,322,939 F791L probably damaging Het
Ranbp2 A G 10: 58,464,078 probably null Het
Serpinb9e A G 13: 33,255,125 K178R probably damaging Het
Shtn1 A G 19: 59,028,169 S233P probably damaging Het
Smpd1 G A 7: 105,555,342 V143M possibly damaging Het
Terb1 G A 8: 104,473,014 H433Y probably benign Het
Traf6 C T 2: 101,690,098 Q164* probably null Het
Trip12 C A 1: 84,814,910 R4L probably damaging Het
Ttn G A 2: 76,863,535 P208S possibly damaging Het
Ube2c T C 2: 164,771,312 I50T probably damaging Het
Uggt1 T C 1: 36,161,694 D1174G probably damaging Het
Vmn2r121 T G X: 124,132,300 M387L probably benign Het
Vmn2r18 T A 5: 151,586,764 N48I probably benign Het
Zc3h15 T C 2: 83,660,173 L217P probably damaging Het
Zyg11a T A 4: 108,205,217 E129V probably damaging Het
Other mutations in Prss29
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01120:Prss29 APN 17 25322133 missense probably benign 0.05
IGL01670:Prss29 APN 17 25322463 missense probably benign 0.03
IGL02516:Prss29 APN 17 25320901 missense probably damaging 1.00
R1538:Prss29 UTSW 17 25320283 start codon destroyed possibly damaging 0.93
R4285:Prss29 UTSW 17 25322257 missense probably damaging 1.00
R5148:Prss29 UTSW 17 25320907 missense probably benign 0.00
R5468:Prss29 UTSW 17 25321046 missense possibly damaging 0.95
R5483:Prss29 UTSW 17 25322203 missense probably benign 0.00
R5852:Prss29 UTSW 17 25322434 missense probably benign 0.01
R6226:Prss29 UTSW 17 25320539 missense possibly damaging 0.74
R6346:Prss29 UTSW 17 25321110 missense possibly damaging 0.83
R7430:Prss29 UTSW 17 25321139 critical splice donor site probably null
R7547:Prss29 UTSW 17 25320922 missense probably damaging 1.00
Posted On2013-12-09