Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01635:Cfap95'

92961

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cfap95

Ensembl Gene

ENSMUSG00000033053

Gene Name

cilia and flagella associated protein 95

Synonyms

1700028P14Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL01635

Quality Score

Status

Chromosome

Chromosomal Location

23536124-23630176 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 23536379 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 176 (Y176C)

Ref Sequence

ENSEMBL: ENSMUSP00000048680 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035849]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000035849
AA Change: Y176C

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000048680
Gene: ENSMUSG00000033053
AA Change: Y176C

Domain	Start	End	E-Value	Type
Pfam:DUF4572	28	219	1.3e-89	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abat	A	G	16: 8,431,910 (GRCm39)	I396V	probably benign	Het
Bag2	T	A	1: 33,786,013 (GRCm39)	N103I	possibly damaging	Het
Chd1	T	C	17: 17,598,858 (GRCm39)	S107P	probably damaging	Het
Chd3	A	T	11: 69,252,076 (GRCm39)		probably benign	Het
Cytip	T	C	2: 58,038,243 (GRCm39)	E106G	probably damaging	Het
Dcp1b	T	A	6: 119,183,498 (GRCm39)	I195N	probably damaging	Het
Ddhd1	C	A	14: 45,867,037 (GRCm39)	V322F	probably null	Het
Esrrg	A	T	1: 187,930,797 (GRCm39)	D296V	probably damaging	Het
F5	A	G	1: 164,035,427 (GRCm39)	K1867R	probably benign	Het
Gm10717	C	A	9: 3,025,511 (GRCm39)	A32D	probably damaging	Het
Gm10717	C	A	9: 3,025,506 (GRCm39)	F30L	possibly damaging	Het
Gstt1	G	T	10: 75,629,951 (GRCm39)	T54K	probably damaging	Het
Ighmbp2	C	T	19: 3,317,265 (GRCm39)	V536I	possibly damaging	Het
Mphosph8	A	T	14: 56,910,003 (GRCm39)	R119W	probably damaging	Het
Negr1	A	G	3: 156,267,929 (GRCm39)	D33G	probably benign	Het
Or2l13b	A	G	16: 19,348,845 (GRCm39)	V275A	probably benign	Het
Or7d10	A	T	9: 19,831,780 (GRCm39)	I92L	probably damaging	Het
Plbd2	T	C	5: 120,637,114 (GRCm39)	D116G	probably damaging	Het
Pold1	A	T	7: 44,185,401 (GRCm39)	V733E	probably damaging	Het
Prorsd1	T	A	11: 29,463,467 (GRCm39)	K98N	probably benign	Het
Rasal2	G	T	1: 156,991,394 (GRCm39)	L611I	probably damaging	Het
Rffl	G	A	11: 82,703,378 (GRCm39)	R147C	probably benign	Het
Rpl27rt	A	T	18: 34,870,795 (GRCm39)	M110L	probably benign	Het
Sdad1	A	G	5: 92,445,019 (GRCm39)	M315T	probably damaging	Het
Shprh	T	A	10: 11,045,763 (GRCm39)	Y861*	probably null	Het
Six4	G	A	12: 73,155,971 (GRCm39)	A324V	probably benign	Het
Stab2	T	C	10: 86,816,992 (GRCm39)	D135G	probably benign	Het
Tada3	T	C	6: 113,352,973 (GRCm39)	H12R	probably benign	Het
Zap70	A	G	1: 36,810,238 (GRCm39)	D116G	probably damaging	Het

Other mutations in Cfap95

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01329:Cfap95	APN	19	23,630,100 (GRCm39)	utr 5 prime	probably benign
IGL01999:Cfap95	APN	19	23,569,529 (GRCm39)	missense	possibly damaging	0.93
IGL03011:Cfap95	APN	19	23,630,017 (GRCm39)	missense	unknown
R0036:Cfap95	UTSW	19	23,593,932 (GRCm39)	unclassified	probably benign
R0894:Cfap95	UTSW	19	23,630,062 (GRCm39)	missense	unknown
R3898:Cfap95	UTSW	19	23,570,466 (GRCm39)	missense	probably benign	0.07
R4771:Cfap95	UTSW	19	23,536,337 (GRCm39)	missense	probably damaging	0.98
R8959:Cfap95	UTSW	19	23,536,385 (GRCm39)	missense	possibly damaging	0.85

Posted On

2013-12-09