Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01637:Vwf'

93042

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vwf

Ensembl Gene

ENSMUSG00000001930

Gene Name

Von Willebrand factor

Synonyms

6820430P06Rik, B130011O06Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.165) question?

Stock #

IGL01637

Quality Score

Status

Chromosome

Chromosomal Location

125546774-125686679 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 125645736 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Asparagine at position 1718 (I1718N)

Ref Sequence

ENSEMBL: ENSMUSP00000107873 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000112254]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000112254
AA Change: I1718N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000107873
Gene: ENSMUSG00000001930
AA Change: I1718N

Domain	Start	End	E-Value	Type
VWD	23	181	3.43e-35	SMART
C8	221	295	1.11e-21	SMART
Pfam:TIL	298	351	6.9e-15	PFAM
VWC	353	413	8.71e-1	SMART
VWD	380	543	2.93e-52	SMART
C8	580	652	3.82e-25	SMART
Pfam:TIL	655	710	4.1e-14	PFAM
EGF_like	790	825	4.37e1	SMART
VWC	832	901	3.29e-3	SMART
VWD	859	1015	5.15e-39	SMART
C8	1056	1130	1.01e-33	SMART
Pfam:TIL	1144	1199	1.3e-9	PFAM
VWA	1278	1461	1.81e-20	SMART
low complexity region	1464	1477	N/A	INTRINSIC
VWA	1499	1672	8.43e-39	SMART
VWA	1692	1875	2.83e-31	SMART
VWC	1882	1949	2.99e0	SMART
VWD	1941	2104	5.03e-42	SMART
C8	2135	2203	1.29e-13	SMART
Pfam:TIL	2206	2257	8.3e-8	PFAM
VWC	2260	2328	3.16e-16	SMART
low complexity region	2417	2428	N/A	INTRINSIC
VWC	2434	2497	2.61e-17	SMART
VWC	2513	2577	3.37e0	SMART
VWC	2585	2647	2.55e-11	SMART
CT	2730	2815	1.37e-31	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134073

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000141521

Predicted Effect

probably benign
Transcript: ENSMUST00000147101

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
PHENOTYPE: Homozygous null mutants exhibit hemostatic and thrombotic defects similar to human von Willebrand disease. Mutants have prolonged bleeding time, newborns occasionally show fatal intra-abdominal bleeding and some adults have detectable fecal occult blood. [provided by MGI curators]

Allele List at MGI

All alleles(33) : Targeted, knock-out(1) Gene trapped(32)

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actn4	A	T	7: 28,904,684 (GRCm38)	I384N	probably damaging	Het
Adsl	G	T	15: 80,948,700 (GRCm38)	Q51H	probably null	Het
Apcdd1	A	G	18: 62,937,286 (GRCm38)	E208G	probably damaging	Het
Arrdc4	G	A	7: 68,744,832 (GRCm38)	R155*	probably null	Het
Atp9b	T	C	18: 80,756,455 (GRCm38)	E823G	probably benign	Het
Bmp1	A	G	14: 70,492,461 (GRCm38)	W468R	probably damaging	Het
C6	A	G	15: 4,759,917 (GRCm38)	I281M	possibly damaging	Het
Ccdc88b	T	C	19: 6,846,710 (GRCm38)	T1392A	probably benign	Het
Dhx34	G	T	7: 16,205,473 (GRCm38)	S665Y	probably damaging	Het
Dock1	A	T	7: 135,137,813 (GRCm38)		probably null	Het
Dpp7	T	C	2: 25,354,613 (GRCm38)	N252S	probably benign	Het
Dyrk2	A	G	10: 118,860,507 (GRCm38)	V282A	probably damaging	Het
Edrf1	T	C	7: 133,650,525 (GRCm38)	L401P	probably damaging	Het
Epc1	A	G	18: 6,439,724 (GRCm38)	V150A	probably benign	Het
Fam170a	A	T	18: 50,281,667 (GRCm38)	M127L	possibly damaging	Het
Fam19a3	C	T	3: 104,773,079 (GRCm38)	V75M	probably damaging	Het
Gabrg1	T	A	5: 70,777,205 (GRCm38)	T277S	probably damaging	Het
Galntl5	T	C	5: 25,189,825 (GRCm38)		probably benign	Het
Gbp2b	A	G	3: 142,598,312 (GRCm38)	N56S	probably damaging	Het
Gfm2	T	A	13: 97,150,409 (GRCm38)	V172E	probably damaging	Het
Gm10419	T	C	5: 108,372,358 (GRCm38)		probably benign	Het
Gm7293	A	G	9: 51,623,606 (GRCm38)		noncoding transcript	Het
Gstm3	T	C	3: 107,967,633 (GRCm38)	E101G	probably damaging	Het
Ifnlr1	T	C	4: 135,686,545 (GRCm38)	W2R	possibly damaging	Het
Ighv13-1	A	T	12: 114,267,733 (GRCm38)		probably benign	Het
Ighv7-1	T	A	12: 113,896,503 (GRCm38)	I90F	possibly damaging	Het
Itga2b	A	G	11: 102,455,583 (GRCm38)	L1009P	probably damaging	Het
Kif1a	A	G	1: 93,039,853 (GRCm38)	V1112A	possibly damaging	Het
Kif5a	A	T	10: 127,245,368 (GRCm38)	D232E	possibly damaging	Het
Klb	G	A	5: 65,375,679 (GRCm38)		probably null	Het
Lrriq1	G	A	10: 103,215,628 (GRCm38)	A421V	probably benign	Het
Mdga1	G	A	17: 29,839,871 (GRCm38)	R721C	probably damaging	Het
Mrpl48	G	T	7: 100,550,532 (GRCm38)		probably benign	Het
Myo18b	T	A	5: 112,840,629 (GRCm38)	R1030S	possibly damaging	Het
Nf1	T	A	11: 79,547,120 (GRCm38)	H2101Q	probably damaging	Het
Nlrp3	C	A	11: 59,549,378 (GRCm38)	L594I	probably damaging	Het
Notch2	C	T	3: 98,146,060 (GRCm38)	T2013I	probably damaging	Het
Olfr1018	A	T	2: 85,822,988 (GRCm38)	T6S	probably benign	Het
Olfr131	G	A	17: 38,082,103 (GRCm38)	L292F	possibly damaging	Het
Olfr593	C	A	7: 103,212,177 (GRCm38)	R95S	probably benign	Het
Olfr812	A	G	10: 129,842,610 (GRCm38)	L144P	probably benign	Het
Olfr845	T	C	9: 19,338,964 (GRCm38)	F168S	probably damaging	Het
Panx3	T	C	9: 37,664,056 (GRCm38)	D170G	probably damaging	Het
Pclo	A	G	5: 14,540,034 (GRCm38)	S783G	unknown	Het
Pde3b	T	A	7: 114,526,901 (GRCm38)	L790*	probably null	Het
Pik3r2	T	C	8: 70,772,348 (GRCm38)		probably benign	Het
Rassf4	A	G	6: 116,641,690 (GRCm38)	F211L	probably damaging	Het
Rbl2	C	T	8: 91,106,438 (GRCm38)	P666S	probably benign	Het
Rnf123	A	G	9: 108,058,238 (GRCm38)	F979L	probably damaging	Het
Rock2	T	A	12: 16,965,171 (GRCm38)	D788E	probably benign	Het
Serpina3b	A	G	12: 104,132,957 (GRCm38)	T244A	probably benign	Het
Setd1b	T	C	5: 123,148,513 (GRCm38)	S541P	unknown	Het
Slc12a4	T	C	8: 105,960,707 (GRCm38)	D60G	possibly damaging	Het
Stac2	T	C	11: 98,041,354 (GRCm38)	E241G	probably benign	Het
Tas2r115	A	G	6: 132,737,629 (GRCm38)	Y120H	probably damaging	Het
Tmtc2	A	T	10: 105,370,085 (GRCm38)	F450I	probably benign	Het
Txnl1	A	T	18: 63,674,191 (GRCm38)	I198N	probably damaging	Het
Ubr2	A	T	17: 46,956,654 (GRCm38)	M1049K	probably damaging	Het
Ugt2b5	T	C	5: 87,139,900 (GRCm38)	E136G	probably benign	Het
Unc13b	C	T	4: 43,241,066 (GRCm38)	T3623I	probably damaging	Het
Usp13	T	A	3: 32,919,064 (GRCm38)	S797T	probably benign	Het
Vmn1r173	A	T	7: 23,702,948 (GRCm38)	T203S	probably damaging	Het
Zfr	A	G	15: 12,159,646 (GRCm38)	H676R	probably benign	Het

Other mutations in Vwf

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00489:Vwf	APN	6	125,658,872 (GRCm38)	missense	unknown
IGL00561:Vwf	APN	6	125,642,721 (GRCm38)	missense	possibly damaging	0.88
IGL01104:Vwf	APN	6	125,683,556 (GRCm38)	missense	probably damaging	1.00
IGL01404:Vwf	APN	6	125,677,970 (GRCm38)	missense	probably damaging	1.00
IGL01539:Vwf	APN	6	125,590,262 (GRCm38)	missense	possibly damaging	0.85
IGL01550:Vwf	APN	6	125,679,289 (GRCm38)	missense	probably benign	0.00
IGL01563:Vwf	APN	6	125,591,165 (GRCm38)	missense	probably damaging	1.00
IGL01720:Vwf	APN	6	125,642,835 (GRCm38)	missense	possibly damaging	0.69
IGL01834:Vwf	APN	6	125,590,170 (GRCm38)	splice site	probably benign
IGL02103:Vwf	APN	6	125,646,355 (GRCm38)	missense	probably damaging	1.00
IGL02120:Vwf	APN	6	125,616,034 (GRCm38)	missense	probably benign	0.26
IGL02174:Vwf	APN	6	125,555,395 (GRCm38)	missense	probably damaging	1.00
IGL02203:Vwf	APN	6	125,642,406 (GRCm38)	missense	probably damaging	1.00
IGL02420:Vwf	APN	6	125,677,916 (GRCm38)	missense	probably benign	0.00
IGL02723:Vwf	APN	6	125,642,930 (GRCm38)	missense	possibly damaging	0.85
IGL02818:Vwf	APN	6	125,663,548 (GRCm38)	missense	probably benign
IGL02931:Vwf	APN	6	125,615,968 (GRCm38)	missense	possibly damaging	0.68
IGL03015:Vwf	APN	6	125,684,138 (GRCm38)	splice site	probably benign
IGL03038:Vwf	APN	6	125,604,157 (GRCm38)	missense	possibly damaging	0.92
IGL03060:Vwf	APN	6	125,663,560 (GRCm38)	missense	probably damaging	1.00
IGL03114:Vwf	APN	6	125,599,363 (GRCm38)	nonsense	probably null
IGL03266:Vwf	APN	6	125,678,077 (GRCm38)	splice site	probably benign
gingerman	UTSW	6	125,662,963 (GRCm38)	critical splice acceptor site	probably null
R0605_vwf_644	UTSW	6	125,685,837 (GRCm38)	missense	probably benign	0.02
R1575_Vwf_091	UTSW	6	125,663,571 (GRCm38)	nonsense	probably null
R1628_Vwf_608	UTSW	6	125,647,738 (GRCm38)	unclassified	probably benign
R1669_Vwf_448	UTSW	6	125,647,906 (GRCm38)	missense	possibly damaging	0.92
R1833_Vwf_948	UTSW	6	125,642,037 (GRCm38)	missense	probably benign	0.14
R2130_vwf_946	UTSW	6	125,657,057 (GRCm38)	missense	probably damaging	1.00
R6360_Vwf_065	UTSW	6	125,683,526 (GRCm38)	missense	probably benign	0.13
R7900_Vwf_938	UTSW	6	125,628,476 (GRCm38)	critical splice donor site	probably null
Russiahouse	UTSW	6	125,639,341 (GRCm38)	nonsense	probably null
B5639:Vwf	UTSW	6	125,642,984 (GRCm38)	missense	probably damaging	1.00
R0025:Vwf	UTSW	6	125,682,812 (GRCm38)	missense	probably benign	0.05
R0025:Vwf	UTSW	6	125,682,812 (GRCm38)	missense	probably benign	0.05
R0087:Vwf	UTSW	6	125,645,954 (GRCm38)	missense	probably benign	0.03
R0194:Vwf	UTSW	6	125,643,297 (GRCm38)	missense	probably benign
R0206:Vwf	UTSW	6	125,637,456 (GRCm38)	missense	probably damaging	1.00
R0233:Vwf	UTSW	6	125,686,510 (GRCm38)	missense	possibly damaging	0.91
R0233:Vwf	UTSW	6	125,686,510 (GRCm38)	missense	possibly damaging	0.91
R0390:Vwf	UTSW	6	125,626,361 (GRCm38)	nonsense	probably null
R0427:Vwf	UTSW	6	125,673,939 (GRCm38)	missense	probably benign
R0437:Vwf	UTSW	6	125,566,318 (GRCm38)	missense	probably damaging	1.00
R0470:Vwf	UTSW	6	125,628,428 (GRCm38)	missense	possibly damaging	0.70
R0499:Vwf	UTSW	6	125,638,114 (GRCm38)	missense	probably benign	0.10
R0554:Vwf	UTSW	6	125,642,781 (GRCm38)	missense	probably benign	0.13
R0605:Vwf	UTSW	6	125,685,837 (GRCm38)	missense	probably benign	0.02
R0711:Vwf	UTSW	6	125,626,271 (GRCm38)	missense	probably benign	0.01
R0723:Vwf	UTSW	6	125,566,262 (GRCm38)	missense	probably benign	0.01
R0973:Vwf	UTSW	6	125,643,006 (GRCm38)	missense	probably damaging	1.00
R1054:Vwf	UTSW	6	125,590,227 (GRCm38)	missense	probably damaging	1.00
R1115:Vwf	UTSW	6	125,655,065 (GRCm38)	missense	unknown
R1156:Vwf	UTSW	6	125,637,488 (GRCm38)	missense	probably damaging	1.00
R1191:Vwf	UTSW	6	125,599,252 (GRCm38)	missense	probably damaging	1.00
R1240:Vwf	UTSW	6	125,603,308 (GRCm38)	splice site	probably null
R1398:Vwf	UTSW	6	125,603,457 (GRCm38)	missense	probably benign	0.02
R1435:Vwf	UTSW	6	125,642,249 (GRCm38)	nonsense	probably null
R1528:Vwf	UTSW	6	125,608,291 (GRCm38)	missense	possibly damaging	0.69
R1575:Vwf	UTSW	6	125,663,571 (GRCm38)	nonsense	probably null
R1575:Vwf	UTSW	6	125,655,251 (GRCm38)	missense	unknown
R1628:Vwf	UTSW	6	125,647,738 (GRCm38)	unclassified	probably benign
R1669:Vwf	UTSW	6	125,647,906 (GRCm38)	missense	possibly damaging	0.92
R1699:Vwf	UTSW	6	125,685,900 (GRCm38)	missense	possibly damaging	0.74
R1699:Vwf	UTSW	6	125,643,069 (GRCm38)	missense	probably damaging	1.00
R1725:Vwf	UTSW	6	125,646,282 (GRCm38)	missense	probably benign	0.05
R1742:Vwf	UTSW	6	125,667,550 (GRCm38)	missense	probably benign	0.02
R1809:Vwf	UTSW	6	125,590,175 (GRCm38)	splice site	probably benign
R1833:Vwf	UTSW	6	125,642,037 (GRCm38)	missense	probably benign	0.14
R1866:Vwf	UTSW	6	125,667,529 (GRCm38)	missense	possibly damaging	0.62
R1870:Vwf	UTSW	6	125,642,939 (GRCm38)	missense	probably damaging	1.00
R1874:Vwf	UTSW	6	125,628,372 (GRCm38)	missense	probably benign	0.00
R1941:Vwf	UTSW	6	125,639,279 (GRCm38)	missense	possibly damaging	0.64
R2061:Vwf	UTSW	6	125,591,188 (GRCm38)	missense	probably damaging	0.98
R2103:Vwf	UTSW	6	125,646,330 (GRCm38)	missense	probably benign	0.31
R2104:Vwf	UTSW	6	125,646,330 (GRCm38)	missense	probably benign	0.31
R2130:Vwf	UTSW	6	125,657,057 (GRCm38)	missense	probably damaging	1.00
R2159:Vwf	UTSW	6	125,626,341 (GRCm38)	missense	probably damaging	0.99
R2178:Vwf	UTSW	6	125,642,132 (GRCm38)	missense	possibly damaging	0.90
R2656:Vwf	UTSW	6	125,555,361 (GRCm38)	missense	probably benign	0.00
R2913:Vwf	UTSW	6	125,685,846 (GRCm38)	missense	probably benign	0.08
R2917:Vwf	UTSW	6	125,608,143 (GRCm38)	missense	probably benign	0.07
R3726:Vwf	UTSW	6	125,677,948 (GRCm38)	utr 3 prime	probably benign
R3735:Vwf	UTSW	6	125,588,613 (GRCm38)	missense	probably damaging	1.00
R3774:Vwf	UTSW	6	125,649,099 (GRCm38)	splice site	probably null
R3934:Vwf	UTSW	6	125,555,499 (GRCm38)	missense	probably damaging	1.00
R4291:Vwf	UTSW	6	125,642,322 (GRCm38)	missense	probably damaging	1.00
R4384:Vwf	UTSW	6	125,655,116 (GRCm38)	missense	unknown
R4743:Vwf	UTSW	6	125,684,091 (GRCm38)	critical splice acceptor site	probably null
R4760:Vwf	UTSW	6	125,570,604 (GRCm38)	missense	probably damaging	1.00
R4776:Vwf	UTSW	6	125,566,305 (GRCm38)	missense	possibly damaging	0.53
R4791:Vwf	UTSW	6	125,643,363 (GRCm38)	missense
R4871:Vwf	UTSW	6	125,686,462 (GRCm38)	missense	probably benign	0.25
R4894:Vwf	UTSW	6	125,645,934 (GRCm38)	nonsense	probably null
R4963:Vwf	UTSW	6	125,667,483 (GRCm38)	nonsense	probably null
R5010:Vwf	UTSW	6	125,566,257 (GRCm38)	missense	probably benign	0.15
R5289:Vwf	UTSW	6	125,667,510 (GRCm38)	utr 3 prime	probably benign
R5512:Vwf	UTSW	6	125,673,887 (GRCm38)	utr 3 prime	probably benign
R5523:Vwf	UTSW	6	125,643,042 (GRCm38)	missense
R5642:Vwf	UTSW	6	125,603,418 (GRCm38)	missense
R5860:Vwf	UTSW	6	125,679,265 (GRCm38)	utr 3 prime	probably benign
R5860:Vwf	UTSW	6	125,643,090 (GRCm38)	missense
R5896:Vwf	UTSW	6	125,678,762 (GRCm38)	critical splice acceptor site	probably null
R5926:Vwf	UTSW	6	125,604,174 (GRCm38)	missense	probably damaging	1.00
R5976:Vwf	UTSW	6	125,603,463 (GRCm38)	missense
R6053:Vwf	UTSW	6	125,600,665 (GRCm38)	missense	probably benign	0.21
R6151:Vwf	UTSW	6	125,657,065 (GRCm38)	missense	unknown
R6179:Vwf	UTSW	6	125,649,289 (GRCm38)	missense	unknown
R6181:Vwf	UTSW	6	125,566,146 (GRCm38)	missense	probably damaging	0.98
R6234:Vwf	UTSW	6	125,657,165 (GRCm38)	missense	unknown
R6360:Vwf	UTSW	6	125,683,526 (GRCm38)	missense	probably benign	0.13
R6412:Vwf	UTSW	6	125,679,316 (GRCm38)	missense	probably benign	0.00
R6464:Vwf	UTSW	6	125,639,400 (GRCm38)	critical splice donor site	probably null
R6522:Vwf	UTSW	6	125,662,963 (GRCm38)	critical splice acceptor site	probably null
R6766:Vwf	UTSW	6	125,639,376 (GRCm38)	missense	unknown
R6856:Vwf	UTSW	6	125,642,150 (GRCm38)	nonsense	probably null
R6877:Vwf	UTSW	6	125,657,201 (GRCm38)	missense	possibly damaging	0.48
R6896:Vwf	UTSW	6	125,566,194 (GRCm38)	missense	probably damaging	1.00
R7113:Vwf	UTSW	6	125,655,044 (GRCm38)	missense
R7287:Vwf	UTSW	6	125,637,467 (GRCm38)	missense
R7359:Vwf	UTSW	6	125,566,257 (GRCm38)	missense
R7509:Vwf	UTSW	6	125,642,169 (GRCm38)	missense
R7519:Vwf	UTSW	6	125,667,543 (GRCm38)	missense
R7545:Vwf	UTSW	6	125,614,097 (GRCm38)	missense
R7549:Vwf	UTSW	6	125,626,267 (GRCm38)	missense
R7593:Vwf	UTSW	6	125,647,768 (GRCm38)	missense
R7635:Vwf	UTSW	6	125,682,734 (GRCm38)	missense
R7793:Vwf	UTSW	6	125,686,520 (GRCm38)	missense
R7802:Vwf	UTSW	6	125,666,677 (GRCm38)	missense
R7824:Vwf	UTSW	6	125,658,815 (GRCm38)	missense
R7849:Vwf	UTSW	6	125,656,803 (GRCm38)	missense
R7900:Vwf	UTSW	6	125,628,476 (GRCm38)	critical splice donor site	probably null
R7919:Vwf	UTSW	6	125,647,859 (GRCm38)	missense
R7966:Vwf	UTSW	6	125,639,341 (GRCm38)	nonsense	probably null
R8101:Vwf	UTSW	6	125,570,559 (GRCm38)	nonsense	probably null
R8162:Vwf	UTSW	6	125,645,836 (GRCm38)	splice site	probably null
R8345:Vwf	UTSW	6	125,679,302 (GRCm38)	missense
R8853:Vwf	UTSW	6	125,657,264 (GRCm38)	missense
R9027:Vwf	UTSW	6	125,666,663 (GRCm38)	missense
R9065:Vwf	UTSW	6	125,646,299 (GRCm38)	missense
R9068:Vwf	UTSW	6	125,648,829 (GRCm38)	unclassified	probably benign
R9128:Vwf	UTSW	6	125,642,730 (GRCm38)	missense
R9136:Vwf	UTSW	6	125,599,393 (GRCm38)	splice site	probably benign
R9164:Vwf	UTSW	6	125,565,843 (GRCm38)	missense
R9177:Vwf	UTSW	6	125,604,291 (GRCm38)	missense
R9334:Vwf	UTSW	6	125,677,946 (GRCm38)	missense
R9508:Vwf	UTSW	6	125,555,508 (GRCm38)	missense
R9553:Vwf	UTSW	6	125,600,699 (GRCm38)	missense
R9660:Vwf	UTSW	6	125,591,707 (GRCm38)	missense	possibly damaging	0.61
R9706:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9708:Vwf	UTSW	6	125,657,090 (GRCm38)	missense
R9712:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9714:Vwf	UTSW	6	125,624,573 (GRCm38)	missense
R9728:Vwf	UTSW	6	125,591,707 (GRCm38)	missense	possibly damaging	0.61
R9758:Vwf	UTSW	6	125,626,267 (GRCm38)	missense
X0021:Vwf	UTSW	6	125,646,331 (GRCm38)	missense	probably damaging	1.00
X0065:Vwf	UTSW	6	125,603,433 (GRCm38)	missense	probably null	0.05
Z1176:Vwf	UTSW	6	125,603,308 (GRCm38)	splice site	probably null
Z1176:Vwf	UTSW	6	125,591,231 (GRCm38)	missense

Posted On

2013-12-09