Incidental Mutation 'IGL01637:Rnf123'
| ID |
93061 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Rnf123
|
| Ensembl Gene |
ENSMUSG00000041528 |
| Gene Name |
ring finger protein 123 |
| Synonyms |
KPC1 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.174)
|
| Stock # |
IGL01637
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
9 |
| Chromosomal Location |
108051534-108083346 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 108058238 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 979
(F979L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125495
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047746]
[ENSMUST00000085060]
[ENSMUST00000160249]
[ENSMUST00000160649]
[ENSMUST00000162355]
[ENSMUST00000162753]
[ENSMUST00000178267]
|
| AlphaFold |
Q5XPI3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047746
AA Change: F985L
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000040803
Gene: ENSMUSG00000041528
AA Change: F985L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000085060
|
| SMART Domains |
Protein: ENSMUSP00000082137
Gene: ENSMUSG00000032593
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
LRRNT
|
33 |
65 |
2.55e-2 |
SMART |
|
LRR
|
65 |
83 |
6.97e1 |
SMART |
|
LRR_TYP
|
84 |
107 |
1.56e-2 |
SMART |
|
LRR
|
109 |
131 |
2.84e1 |
SMART |
|
LRR
|
132 |
155 |
7.05e-1 |
SMART |
|
LRR
|
156 |
176 |
3.98e1 |
SMART |
|
LRR
|
182 |
206 |
5.56e0 |
SMART |
|
Blast:LRRCT
|
219 |
274 |
8e-23 |
BLAST |
|
IG
|
285 |
372 |
1.59e-6 |
SMART |
|
transmembrane domain
|
383 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
422 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
504 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159136
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000159306
AA Change: F110L
|
| SMART Domains |
Protein: ENSMUSP00000125695
Gene: ENSMUSG00000041528
AA Change: F110L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
172 |
192 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160249
AA Change: F979L
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000124548
Gene: ENSMUSG00000041528
AA Change: F979L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160649
AA Change: F979L
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125495
Gene: ENSMUSG00000041528
AA Change: F979L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160841
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161673
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000162123
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162355
AA Change: F985L
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000125745
Gene: ENSMUSG00000041528
AA Change: F985L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162753
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000178267
AA Change: F979L
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000136953
Gene: ENSMUSG00000041528
AA Change: F979L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173683
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actn4 |
A |
T |
7: 28,904,684 (GRCm38) |
I384N |
probably damaging |
Het |
| Adsl |
G |
T |
15: 80,948,700 (GRCm38) |
Q51H |
probably null |
Het |
| Apcdd1 |
A |
G |
18: 62,937,286 (GRCm38) |
E208G |
probably damaging |
Het |
| Arrdc4 |
G |
A |
7: 68,744,832 (GRCm38) |
R155* |
probably null |
Het |
| Atp9b |
T |
C |
18: 80,756,455 (GRCm38) |
E823G |
probably benign |
Het |
| Bmp1 |
A |
G |
14: 70,492,461 (GRCm38) |
W468R |
probably damaging |
Het |
| C6 |
A |
G |
15: 4,759,917 (GRCm38) |
I281M |
possibly damaging |
Het |
| Ccdc88b |
T |
C |
19: 6,846,710 (GRCm38) |
T1392A |
probably benign |
Het |
| Dhx34 |
G |
T |
7: 16,205,473 (GRCm38) |
S665Y |
probably damaging |
Het |
| Dock1 |
A |
T |
7: 135,137,813 (GRCm38) |
|
probably null |
Het |
| Dpp7 |
T |
C |
2: 25,354,613 (GRCm38) |
N252S |
probably benign |
Het |
| Dyrk2 |
A |
G |
10: 118,860,507 (GRCm38) |
V282A |
probably damaging |
Het |
| Edrf1 |
T |
C |
7: 133,650,525 (GRCm38) |
L401P |
probably damaging |
Het |
| Epc1 |
A |
G |
18: 6,439,724 (GRCm38) |
V150A |
probably benign |
Het |
| Fam170a |
A |
T |
18: 50,281,667 (GRCm38) |
M127L |
possibly damaging |
Het |
| Fam19a3 |
C |
T |
3: 104,773,079 (GRCm38) |
V75M |
probably damaging |
Het |
| Gabrg1 |
T |
A |
5: 70,777,205 (GRCm38) |
T277S |
probably damaging |
Het |
| Galntl5 |
T |
C |
5: 25,189,825 (GRCm38) |
|
probably benign |
Het |
| Gbp2b |
A |
G |
3: 142,598,312 (GRCm38) |
N56S |
probably damaging |
Het |
| Gfm2 |
T |
A |
13: 97,150,409 (GRCm38) |
V172E |
probably damaging |
Het |
| Gm10419 |
T |
C |
5: 108,372,358 (GRCm38) |
|
probably benign |
Het |
| Gm7293 |
A |
G |
9: 51,623,606 (GRCm38) |
|
noncoding transcript |
Het |
| Gstm3 |
T |
C |
3: 107,967,633 (GRCm38) |
E101G |
probably damaging |
Het |
| Ifnlr1 |
T |
C |
4: 135,686,545 (GRCm38) |
W2R |
possibly damaging |
Het |
| Ighv13-1 |
A |
T |
12: 114,267,733 (GRCm38) |
|
probably benign |
Het |
| Ighv7-1 |
T |
A |
12: 113,896,503 (GRCm38) |
I90F |
possibly damaging |
Het |
| Itga2b |
A |
G |
11: 102,455,583 (GRCm38) |
L1009P |
probably damaging |
Het |
| Kif1a |
A |
G |
1: 93,039,853 (GRCm38) |
V1112A |
possibly damaging |
Het |
| Kif5a |
A |
T |
10: 127,245,368 (GRCm38) |
D232E |
possibly damaging |
Het |
| Klb |
G |
A |
5: 65,375,679 (GRCm38) |
|
probably null |
Het |
| Lrriq1 |
G |
A |
10: 103,215,628 (GRCm38) |
A421V |
probably benign |
Het |
| Mdga1 |
G |
A |
17: 29,839,871 (GRCm38) |
R721C |
probably damaging |
Het |
| Mrpl48 |
G |
T |
7: 100,550,532 (GRCm38) |
|
probably benign |
Het |
| Myo18b |
T |
A |
5: 112,840,629 (GRCm38) |
R1030S |
possibly damaging |
Het |
| Nf1 |
T |
A |
11: 79,547,120 (GRCm38) |
H2101Q |
probably damaging |
Het |
| Nlrp3 |
C |
A |
11: 59,549,378 (GRCm38) |
L594I |
probably damaging |
Het |
| Notch2 |
C |
T |
3: 98,146,060 (GRCm38) |
T2013I |
probably damaging |
Het |
| Olfr1018 |
A |
T |
2: 85,822,988 (GRCm38) |
T6S |
probably benign |
Het |
| Olfr131 |
G |
A |
17: 38,082,103 (GRCm38) |
L292F |
possibly damaging |
Het |
| Olfr593 |
C |
A |
7: 103,212,177 (GRCm38) |
R95S |
probably benign |
Het |
| Olfr812 |
A |
G |
10: 129,842,610 (GRCm38) |
L144P |
probably benign |
Het |
| Olfr845 |
T |
C |
9: 19,338,964 (GRCm38) |
F168S |
probably damaging |
Het |
| Panx3 |
T |
C |
9: 37,664,056 (GRCm38) |
D170G |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,540,034 (GRCm38) |
S783G |
unknown |
Het |
| Pde3b |
T |
A |
7: 114,526,901 (GRCm38) |
L790* |
probably null |
Het |
| Pik3r2 |
T |
C |
8: 70,772,348 (GRCm38) |
|
probably benign |
Het |
| Rassf4 |
A |
G |
6: 116,641,690 (GRCm38) |
F211L |
probably damaging |
Het |
| Rbl2 |
C |
T |
8: 91,106,438 (GRCm38) |
P666S |
probably benign |
Het |
| Rock2 |
T |
A |
12: 16,965,171 (GRCm38) |
D788E |
probably benign |
Het |
| Serpina3b |
A |
G |
12: 104,132,957 (GRCm38) |
T244A |
probably benign |
Het |
| Setd1b |
T |
C |
5: 123,148,513 (GRCm38) |
S541P |
unknown |
Het |
| Slc12a4 |
T |
C |
8: 105,960,707 (GRCm38) |
D60G |
possibly damaging |
Het |
| Stac2 |
T |
C |
11: 98,041,354 (GRCm38) |
E241G |
probably benign |
Het |
| Tas2r115 |
A |
G |
6: 132,737,629 (GRCm38) |
Y120H |
probably damaging |
Het |
| Tmtc2 |
A |
T |
10: 105,370,085 (GRCm38) |
F450I |
probably benign |
Het |
| Txnl1 |
A |
T |
18: 63,674,191 (GRCm38) |
I198N |
probably damaging |
Het |
| Ubr2 |
A |
T |
17: 46,956,654 (GRCm38) |
M1049K |
probably damaging |
Het |
| Ugt2b5 |
T |
C |
5: 87,139,900 (GRCm38) |
E136G |
probably benign |
Het |
| Unc13b |
C |
T |
4: 43,241,066 (GRCm38) |
T3623I |
probably damaging |
Het |
| Usp13 |
T |
A |
3: 32,919,064 (GRCm38) |
S797T |
probably benign |
Het |
| Vmn1r173 |
A |
T |
7: 23,702,948 (GRCm38) |
T203S |
probably damaging |
Het |
| Vwf |
T |
A |
6: 125,645,736 (GRCm38) |
I1718N |
probably damaging |
Het |
| Zfr |
A |
G |
15: 12,159,646 (GRCm38) |
H676R |
probably benign |
Het |
|
| Other mutations in Rnf123 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00950:Rnf123
|
APN |
9 |
108,067,395 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01358:Rnf123
|
APN |
9 |
108,069,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01464:Rnf123
|
APN |
9 |
108,052,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01669:Rnf123
|
APN |
9 |
108,058,356 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01905:Rnf123
|
APN |
9 |
108,071,370 (GRCm38) |
splice site |
probably benign |
|
|
IGL02070:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02072:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02073:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02074:Rnf123
|
APN |
9 |
108,066,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02079:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02080:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02231:Rnf123
|
APN |
9 |
108,066,399 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02281:Rnf123
|
APN |
9 |
108,071,452 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02336:Rnf123
|
APN |
9 |
108,061,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02543:Rnf123
|
APN |
9 |
108,066,348 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02565:Rnf123
|
APN |
9 |
108,052,212 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02571:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02572:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02574:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02586:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02589:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02600:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02601:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02602:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02603:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02609:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02628:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02629:Rnf123
|
APN |
9 |
108,070,789 (GRCm38) |
splice site |
probably benign |
|
|
IGL02629:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02630:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02631:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02632:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02650:Rnf123
|
APN |
9 |
108,069,748 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL02690:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02691:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02692:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02693:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02713:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02736:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02929:Rnf123
|
APN |
9 |
108,069,076 (GRCm38) |
missense |
probably benign |
|
|
R1175:Rnf123
|
UTSW |
9 |
108,077,373 (GRCm38) |
missense |
probably benign |
|
|
R1465:Rnf123
|
UTSW |
9 |
108,071,466 (GRCm38) |
splice site |
probably benign |
|
|
R1502:Rnf123
|
UTSW |
9 |
108,068,510 (GRCm38) |
splice site |
probably null |
|
|
R1682:Rnf123
|
UTSW |
9 |
108,077,398 (GRCm38) |
missense |
probably benign |
0.16 |
|
R1817:Rnf123
|
UTSW |
9 |
108,062,926 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1855:Rnf123
|
UTSW |
9 |
108,061,791 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2394:Rnf123
|
UTSW |
9 |
108,063,536 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2483:Rnf123
|
UTSW |
9 |
108,063,521 (GRCm38) |
missense |
probably benign |
0.16 |
|
R3896:Rnf123
|
UTSW |
9 |
108,069,103 (GRCm38) |
splice site |
probably benign |
|
|
R3940:Rnf123
|
UTSW |
9 |
108,064,035 (GRCm38) |
splice site |
probably benign |
|
|
R4206:Rnf123
|
UTSW |
9 |
108,063,963 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4641:Rnf123
|
UTSW |
9 |
108,058,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4714:Rnf123
|
UTSW |
9 |
108,052,439 (GRCm38) |
splice site |
probably null |
|
|
R4767:Rnf123
|
UTSW |
9 |
108,052,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4849:Rnf123
|
UTSW |
9 |
108,056,091 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4899:Rnf123
|
UTSW |
9 |
108,063,680 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5274:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5275:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5276:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5294:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5295:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5394:Rnf123
|
UTSW |
9 |
108,070,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5717:Rnf123
|
UTSW |
9 |
108,067,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6186:Rnf123
|
UTSW |
9 |
108,069,958 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R6449:Rnf123
|
UTSW |
9 |
108,056,053 (GRCm38) |
missense |
probably benign |
0.17 |
|
R6502:Rnf123
|
UTSW |
9 |
108,068,332 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R6944:Rnf123
|
UTSW |
9 |
108,063,623 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7003:Rnf123
|
UTSW |
9 |
108,063,683 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7088:Rnf123
|
UTSW |
9 |
108,058,536 (GRCm38) |
missense |
probably null |
1.00 |
|
R7092:Rnf123
|
UTSW |
9 |
108,068,600 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7100:Rnf123
|
UTSW |
9 |
108,056,639 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7257:Rnf123
|
UTSW |
9 |
108,069,029 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7453:Rnf123
|
UTSW |
9 |
108,070,408 (GRCm38) |
splice site |
probably null |
|
|
R7468:Rnf123
|
UTSW |
9 |
108,069,009 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7517:Rnf123
|
UTSW |
9 |
108,070,274 (GRCm38) |
nonsense |
probably null |
|
|
R7577:Rnf123
|
UTSW |
9 |
108,070,619 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8296:Rnf123
|
UTSW |
9 |
108,062,890 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8322:Rnf123
|
UTSW |
9 |
108,068,507 (GRCm38) |
missense |
probably benign |
0.26 |
|
R8754:Rnf123
|
UTSW |
9 |
108,071,164 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8783:Rnf123
|
UTSW |
9 |
108,069,073 (GRCm38) |
missense |
probably benign |
|
|
R9052:Rnf123
|
UTSW |
9 |
108,059,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9156:Rnf123
|
UTSW |
9 |
108,063,028 (GRCm38) |
splice site |
probably benign |
|
|
R9170:Rnf123
|
UTSW |
9 |
108,071,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9332:Rnf123
|
UTSW |
9 |
108,067,505 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9385:Rnf123
|
UTSW |
9 |
108,052,268 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9394:Rnf123
|
UTSW |
9 |
108,065,706 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9432:Rnf123
|
UTSW |
9 |
108,059,809 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9717:Rnf123
|
UTSW |
9 |
108,077,764 (GRCm38) |
missense |
probably benign |
0.43 |
|
Z1176:Rnf123
|
UTSW |
9 |
108,062,981 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Rnf123
|
UTSW |
9 |
108,058,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2013-12-09 |
Incidental Mutation