Incidental Mutation 'IGL01640:Vmn1r116'
ID93090
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r116
Ensembl Gene ENSMUSG00000095973
Gene Namevomeronasal 1 receptor 116
SynonymsGm8547
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01640
Quality Score
Status
Chromosome7
Chromosomal Location20872256-20873179 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 20872448 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 65 (T65A)
Ref Sequence ENSEMBL: ENSMUSP00000128742 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164288]
Predicted Effect probably benign
Transcript: ENSMUST00000164288
AA Change: T65A

PolyPhen 2 Score 0.297 (Sensitivity: 0.91; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000128742
Gene: ENSMUSG00000095973
AA Change: T65A

DomainStartEndE-ValueType
Pfam:TAS2R 8 299 7.8e-15 PFAM
Pfam:7tm_1 31 290 8.6e-8 PFAM
Pfam:V1R 41 297 8.8e-17 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700003H04Rik T C 3: 124,579,938 T3A probably damaging Het
4933402N03Rik A T 7: 131,139,119 S123T possibly damaging Het
Adamts17 A T 7: 67,029,680 T559S probably damaging Het
Adh4 C T 3: 138,429,027 probably benign Het
Arel1 G A 12: 84,920,701 T783M probably damaging Het
B3gntl1 C T 11: 121,673,020 E5K probably benign Het
Faf1 T A 4: 109,840,403 F309I probably damaging Het
Fhod3 T G 18: 25,115,793 M1343R probably benign Het
Fnbp1 A G 2: 31,105,291 F44L probably damaging Het
Gm3633 A T 14: 42,638,367 Y206* probably null Het
Gprc6a A C 10: 51,627,084 F228V probably damaging Het
Il31ra T C 13: 112,531,758 I453V possibly damaging Het
Kif2a A G 13: 106,974,552 I529T probably damaging Het
Lrrc19 C T 4: 94,638,508 V271I probably damaging Het
Ncaph2 A G 15: 89,363,838 probably null Het
Nek5 A G 8: 22,120,840 I49T probably benign Het
Nhlrc3 A T 3: 53,453,537 probably benign Het
Olfr616 A G 7: 103,565,021 V86A probably damaging Het
Olfr659 A T 7: 104,671,664 S321C probably damaging Het
Olfr945 C A 9: 39,258,263 M136I probably damaging Het
Pcnx2 T C 8: 125,801,558 T1308A probably benign Het
Pla2g6 T C 15: 79,304,313 N448S probably benign Het
Pole T A 5: 110,298,266 L571Q probably null Het
Rufy1 A G 11: 50,390,378 probably benign Het
Sftpd C A 14: 41,172,635 A276S probably benign Het
Slc35f4 A C 14: 49,318,768 V176G probably damaging Het
Snrpb T C 2: 130,175,331 D89G probably benign Het
Stab2 A T 10: 86,954,171 V577D probably benign Het
Synrg A C 11: 83,981,508 S152R probably damaging Het
Tcrg-V7 T C 13: 19,178,090 probably benign Het
Trpm1 A G 7: 64,226,897 E682G probably damaging Het
Unc80 T C 1: 66,679,585 I2989T probably benign Het
Zfp469 G A 8: 122,271,270 probably benign Het
Other mutations in Vmn1r116
AlleleSourceChrCoordTypePredicted EffectPPH Score
R7381:Vmn1r116 UTSW 7 20872511 nonsense probably null
R7694:Vmn1r116 UTSW 7 20872412 missense possibly damaging 0.78
R8686:Vmn1r116 UTSW 7 20872691 missense probably damaging 1.00
Posted On2013-12-09