Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01640:Gm3633'

93091

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm3633

Ensembl Gene

ENSMUSG00000095113

Gene Name

predicted gene 3633

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL01640

Quality Score

Status

Chromosome

Chromosomal Location

42458509-42463864 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 42460324 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Stop codon at position 206 (Y206*)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000163102]

AlphaFold

F6YU13

Predicted Effect

probably null
Transcript: ENSMUST00000100697
AA Change: Y206*

SMART Domains

Protein: ENSMUSP00000098262
Gene: ENSMUSG00000095113
AA Change: Y206*

Domain	Start	End	E-Value	Type
Pfam:Takusan	57	137	2.9e-26	PFAM
coiled coil region	164	186	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000163102

SMART Domains

Protein: ENSMUSP00000126330
Gene: ENSMUSG00000095113

Domain	Start	End	E-Value	Type
Pfam:Takusan	1	32	6.1e-9	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700003H04Rik	T	C	3: 124,373,587 (GRCm39)	T3A	probably damaging	Het
4933402N03Rik	A	T	7: 130,740,848 (GRCm39)	S123T	possibly damaging	Het
Adamts17	A	T	7: 66,679,428 (GRCm39)	T559S	probably damaging	Het
Adh4	C	T	3: 138,134,788 (GRCm39)		probably benign	Het
Arel1	G	A	12: 84,967,475 (GRCm39)	T783M	probably damaging	Het
B3gntl1	C	T	11: 121,563,846 (GRCm39)	E5K	probably benign	Het
Faf1	T	A	4: 109,697,600 (GRCm39)	F309I	probably damaging	Het
Fhod3	T	G	18: 25,248,850 (GRCm39)	M1343R	probably benign	Het
Fnbp1	A	G	2: 30,995,303 (GRCm39)	F44L	probably damaging	Het
Gprc6a	A	C	10: 51,503,180 (GRCm39)	F228V	probably damaging	Het
Il31ra	T	C	13: 112,668,292 (GRCm39)	I453V	possibly damaging	Het
Kif2a	A	G	13: 107,111,060 (GRCm39)	I529T	probably damaging	Het
Lrrc19	C	T	4: 94,526,745 (GRCm39)	V271I	probably damaging	Het
Ncaph2	A	G	15: 89,248,041 (GRCm39)		probably null	Het
Nek5	A	G	8: 22,610,856 (GRCm39)	I49T	probably benign	Het
Nhlrc3	A	T	3: 53,360,958 (GRCm39)		probably benign	Het
Or51ac3	A	G	7: 103,214,228 (GRCm39)	V86A	probably damaging	Het
Or52n20	A	T	7: 104,320,871 (GRCm39)	S321C	probably damaging	Het
Or8g28	C	A	9: 39,169,559 (GRCm39)	M136I	probably damaging	Het
Pcnx2	T	C	8: 126,528,297 (GRCm39)	T1308A	probably benign	Het
Pla2g6	T	C	15: 79,188,513 (GRCm39)	N448S	probably benign	Het
Pole	T	A	5: 110,446,132 (GRCm39)	L571Q	probably null	Het
Rufy1	A	G	11: 50,281,205 (GRCm39)		probably benign	Het
Sftpd	C	A	14: 40,894,592 (GRCm39)	A276S	probably benign	Het
Slc35f4	A	C	14: 49,556,225 (GRCm39)	V176G	probably damaging	Het
Snrpb	T	C	2: 130,017,251 (GRCm39)	D89G	probably benign	Het
Stab2	A	T	10: 86,790,035 (GRCm39)	V577D	probably benign	Het
Synrg	A	C	11: 83,872,334 (GRCm39)	S152R	probably damaging	Het
Trgv7	T	C	13: 19,362,260 (GRCm39)		probably benign	Het
Trpm1	A	G	7: 63,876,645 (GRCm39)	E682G	probably damaging	Het
Unc80	T	C	1: 66,718,744 (GRCm39)	I2989T	probably benign	Het
Vmn1r116	A	G	7: 20,606,373 (GRCm39)	T65A	probably benign	Het
Zfp469	G	A	8: 122,998,009 (GRCm39)		probably benign	Het

Other mutations in Gm3633

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01335:Gm3633	APN	14	42,462,595 (GRCm39)	unclassified	probably benign
IGL01875:Gm3633	APN	14	42,461,234 (GRCm39)	missense	probably damaging	1.00
IGL01912:Gm3633	APN	14	42,462,743 (GRCm39)	unclassified	probably benign
R5039:Gm3633	UTSW	14	42,461,161 (GRCm39)	missense	possibly damaging	0.78
R6866:Gm3633	UTSW	14	42,462,579 (GRCm39)	unclassified	probably benign
R8298:Gm3633	UTSW	14	42,462,675 (GRCm39)	missense
R8687:Gm3633	UTSW	14	42,462,648 (GRCm39)	missense
R9214:Gm3633	UTSW	14	42,460,359 (GRCm39)	unclassified	probably benign
R9397:Gm3633	UTSW	14	42,460,400 (GRCm39)	missense

Posted On

2013-12-09