Incidental Mutation 'IGL01640:4933402N03Rik'
ID93111
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 4933402N03Rik
Ensembl Gene ENSMUSG00000013668
Gene NameRIKEN cDNA 4933402N03 gene
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01640
Quality Score
Status
Chromosome7
Chromosomal Location131137713-131146314 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 131139119 bp
ZygosityHeterozygous
Amino Acid Change Serine to Threonine at position 123 (S123T)
Ref Sequence ENSEMBL: ENSMUSP00000070291 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000070980] [ENSMUST00000124096]
Predicted Effect possibly damaging
Transcript: ENSMUST00000070980
AA Change: S123T

PolyPhen 2 Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
Predicted Effect probably benign
Transcript: ENSMUST00000124096
SMART Domains Protein: ENSMUSP00000130971
Gene: ENSMUSG00000030849

DomainStartEndE-ValueType
Pfam:Pkinase 1 118 4.8e-19 PFAM
Pfam:Pkinase_Tyr 1 118 1.7e-50 PFAM
low complexity region 146 160 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700003H04Rik T C 3: 124,579,938 T3A probably damaging Het
Adamts17 A T 7: 67,029,680 T559S probably damaging Het
Adh4 C T 3: 138,429,027 probably benign Het
Arel1 G A 12: 84,920,701 T783M probably damaging Het
B3gntl1 C T 11: 121,673,020 E5K probably benign Het
Faf1 T A 4: 109,840,403 F309I probably damaging Het
Fhod3 T G 18: 25,115,793 M1343R probably benign Het
Fnbp1 A G 2: 31,105,291 F44L probably damaging Het
Gm3633 A T 14: 42,638,367 Y206* probably null Het
Gprc6a A C 10: 51,627,084 F228V probably damaging Het
Il31ra T C 13: 112,531,758 I453V possibly damaging Het
Kif2a A G 13: 106,974,552 I529T probably damaging Het
Lrrc19 C T 4: 94,638,508 V271I probably damaging Het
Ncaph2 A G 15: 89,363,838 probably null Het
Nek5 A G 8: 22,120,840 I49T probably benign Het
Nhlrc3 A T 3: 53,453,537 probably benign Het
Olfr616 A G 7: 103,565,021 V86A probably damaging Het
Olfr659 A T 7: 104,671,664 S321C probably damaging Het
Olfr945 C A 9: 39,258,263 M136I probably damaging Het
Pcnx2 T C 8: 125,801,558 T1308A probably benign Het
Pla2g6 T C 15: 79,304,313 N448S probably benign Het
Pole T A 5: 110,298,266 L571Q probably null Het
Rufy1 A G 11: 50,390,378 probably benign Het
Sftpd C A 14: 41,172,635 A276S probably benign Het
Slc35f4 A C 14: 49,318,768 V176G probably damaging Het
Snrpb T C 2: 130,175,331 D89G probably benign Het
Stab2 A T 10: 86,954,171 V577D probably benign Het
Synrg A C 11: 83,981,508 S152R probably damaging Het
Tcrg-V7 T C 13: 19,178,090 probably benign Het
Trpm1 A G 7: 64,226,897 E682G probably damaging Het
Unc80 T C 1: 66,679,585 I2989T probably benign Het
Vmn1r116 A G 7: 20,872,448 T65A probably benign Het
Zfp469 G A 8: 122,271,270 probably benign Het
Other mutations in 4933402N03Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01289:4933402N03Rik APN 7 131138621 missense probably benign 0.14
IGL01374:4933402N03Rik APN 7 131146101 missense probably benign 0.34
IGL01394:4933402N03Rik APN 7 131146231 nonsense probably null
IGL01713:4933402N03Rik APN 7 131139043 missense possibly damaging 0.92
H8786:4933402N03Rik UTSW 7 131139177 missense probably damaging 0.96
R0321:4933402N03Rik UTSW 7 131146227 missense probably benign 0.00
R0496:4933402N03Rik UTSW 7 131146131 missense probably benign
R0541:4933402N03Rik UTSW 7 131139143 missense probably benign 0.01
R1527:4933402N03Rik UTSW 7 131138860 missense probably benign 0.10
R1750:4933402N03Rik UTSW 7 131146130 missense probably benign 0.09
R2047:4933402N03Rik UTSW 7 131146107 missense probably damaging 0.96
R2404:4933402N03Rik UTSW 7 131139194 missense possibly damaging 0.94
R3881:4933402N03Rik UTSW 7 131139094 missense probably benign 0.19
R4507:4933402N03Rik UTSW 7 131145872 missense probably damaging 1.00
R4684:4933402N03Rik UTSW 7 131138684 missense probably damaging 0.96
R5368:4933402N03Rik UTSW 7 131139196 missense possibly damaging 0.92
R5814:4933402N03Rik UTSW 7 131139082 missense probably benign 0.09
R6238:4933402N03Rik UTSW 7 131146134 missense probably benign 0.05
Posted On2013-12-09