Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01606:Gm5862'

93410

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Is this an essential gene?

Possibly non essential (E-score: 0.253) question?

Stock #

IGL01606

Quality Score

Status

Chromosome

Chromosomal Location

26017278-26022916 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 26019516 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 152 (T152S)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: T152S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: T152S

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1600012H06Rik	A	G	17: 14,943,863	D84G	probably damaging	Het
Adat3	A	T	10: 80,607,338	I337F	probably damaging	Het
Carmil3	T	A	14: 55,493,849	N128K	possibly damaging	Het
Ceacam2	T	C	7: 25,530,707	E158G	possibly damaging	Het
Cel	T	C	2: 28,560,564	I150V	probably benign	Het
Chd5	A	G	4: 152,360,975	H441R	probably damaging	Het
Clic5	G	T	17: 44,248,746	R109L	probably benign	Het
Cpd	T	C	11: 76,812,640	M466V	probably benign	Het
Cyp39a1	T	A	17: 43,746,618		probably benign	Het
Dnah11	C	A	12: 117,983,032	A3106S	probably benign	Het
Fasn	A	C	11: 120,809,023		probably null	Het
Fat1	G	A	8: 45,023,049	V1688I	probably benign	Het
Fibcd1	A	G	2: 31,833,853	I258T	probably benign	Het
Frem2	C	A	3: 53,653,591	R1165I	possibly damaging	Het
Gm5627	C	T	9: 102,749,486		noncoding transcript	Het
Gnb3	T	A	6: 124,837,255	D154V	probably damaging	Het
Ighv1-14	T	C	12: 114,646,837		noncoding transcript	Het
Klrb1	C	A	6: 128,723,005	E14D	probably benign	Het
Osbpl1a	A	T	18: 12,756,214	D556E	possibly damaging	Het
Pkd1	T	C	17: 24,576,523	V2330A	probably damaging	Het
Pkdrej	T	C	15: 85,817,700	K1345R	possibly damaging	Het
Plxna4	A	G	6: 32,158,001	F1756L	probably damaging	Het
Psg28	A	C	7: 18,430,371	S139A	probably benign	Het
Ptpru	A	T	4: 131,808,481	I395N	possibly damaging	Het
Reps1	A	G	10: 18,107,687	E426G	probably damaging	Het
Rtp4	T	A	16: 23,613,254	S179T	probably benign	Het
Sh3pxd2a	C	A	19: 47,268,596	R561L	probably benign	Het
Slc29a2	T	A	19: 5,027,439	L215Q	possibly damaging	Het
Slc44a4	T	C	17: 34,929,018	F653L	probably damaging	Het
Sulf1	G	T	1: 12,836,204	R490L	possibly damaging	Het
Ttll4	T	C	1: 74,685,893	L602P	probably damaging	Het
Ttn	A	G	2: 76,776,790	V17963A	probably damaging	Het
Urb1	A	G	16: 90,760,459	S1760P	probably damaging	Het
Zmynd11	G	A	13: 9,697,688	R149W	probably damaging	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01863:Gm5862	APN	5	26022771	missense	probably benign
IGL01868:Gm5862	APN	5	26022771	missense	probably benign
IGL01873:Gm5862	APN	5	26022771	missense	probably benign
IGL01881:Gm5862	APN	5	26022771	missense	probably benign
IGL01902:Gm5862	APN	5	26022771	missense	probably benign
IGL01905:Gm5862	APN	5	26022771	missense	probably benign
IGL01909:Gm5862	APN	5	26022771	missense	probably benign
IGL01917:Gm5862	APN	5	26022771	missense	probably benign
IGL01924:Gm5862	APN	5	26022771	missense	probably benign
IGL01927:Gm5862	APN	5	26022771	missense	probably benign
IGL01951:Gm5862	APN	5	26022771	missense	probably benign
IGL03374:Gm5862	APN	5	26019512	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26019492	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26019347	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26019488	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26019348	missense	probably benign
R8291:Gm5862	UTSW	5	26019446	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26021626	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26018487	frame shift	probably null

Posted On

2013-12-09