Incidental Mutation 'IGL01606:Psg28'
ID93421
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Psg28
Ensembl Gene ENSMUSG00000030373
Gene Namepregnancy-specific glycoprotein 28
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL01606
Quality Score
Status
Chromosome7
Chromosomal Location18422536-18432041 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 18430371 bp
ZygosityHeterozygous
Amino Acid Change Serine to Alanine at position 139 (S139A)
Ref Sequence ENSEMBL: ENSMUSP00000019291 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000019291]
Predicted Effect probably benign
Transcript: ENSMUST00000019291
AA Change: S139A

PolyPhen 2 Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
SMART Domains Protein: ENSMUSP00000019291
Gene: ENSMUSG00000030373
AA Change: S139A

DomainStartEndE-ValueType
IG 40 138 1.84e-2 SMART
IG 157 258 1.67e0 SMART
IG 277 376 1.65e-4 SMART
IGc2 394 458 8.31e-10 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1600012H06Rik A G 17: 14,943,863 D84G probably damaging Het
Adat3 A T 10: 80,607,338 I337F probably damaging Het
Carmil3 T A 14: 55,493,849 N128K possibly damaging Het
Ceacam2 T C 7: 25,530,707 E158G possibly damaging Het
Cel T C 2: 28,560,564 I150V probably benign Het
Chd5 A G 4: 152,360,975 H441R probably damaging Het
Clic5 G T 17: 44,248,746 R109L probably benign Het
Cpd T C 11: 76,812,640 M466V probably benign Het
Cyp39a1 T A 17: 43,746,618 probably benign Het
Dnah11 C A 12: 117,983,032 A3106S probably benign Het
Fasn A C 11: 120,809,023 probably null Het
Fat1 G A 8: 45,023,049 V1688I probably benign Het
Fibcd1 A G 2: 31,833,853 I258T probably benign Het
Frem2 C A 3: 53,653,591 R1165I possibly damaging Het
Gm5627 C T 9: 102,749,486 noncoding transcript Het
Gm5862 T A 5: 26,019,516 T152S probably benign Het
Gnb3 T A 6: 124,837,255 D154V probably damaging Het
Ighv1-14 T C 12: 114,646,837 noncoding transcript Het
Klrb1 C A 6: 128,723,005 E14D probably benign Het
Osbpl1a A T 18: 12,756,214 D556E possibly damaging Het
Pkd1 T C 17: 24,576,523 V2330A probably damaging Het
Pkdrej T C 15: 85,817,700 K1345R possibly damaging Het
Plxna4 A G 6: 32,158,001 F1756L probably damaging Het
Ptpru A T 4: 131,808,481 I395N possibly damaging Het
Reps1 A G 10: 18,107,687 E426G probably damaging Het
Rtp4 T A 16: 23,613,254 S179T probably benign Het
Sh3pxd2a C A 19: 47,268,596 R561L probably benign Het
Slc29a2 T A 19: 5,027,439 L215Q possibly damaging Het
Slc44a4 T C 17: 34,929,018 F653L probably damaging Het
Sulf1 G T 1: 12,836,204 R490L possibly damaging Het
Ttll4 T C 1: 74,685,893 L602P probably damaging Het
Ttn A G 2: 76,776,790 V17963A probably damaging Het
Urb1 A G 16: 90,760,459 S1760P probably damaging Het
Zmynd11 G A 13: 9,697,688 R149W probably damaging Het
Other mutations in Psg28
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00673:Psg28 APN 7 18427891 missense probably damaging 1.00
IGL01118:Psg28 APN 7 18428092 missense probably damaging 1.00
R0276:Psg28 UTSW 7 18430396 missense probably benign 0.00
R0391:Psg28 UTSW 7 18426173 missense probably benign 0.02
R0713:Psg28 UTSW 7 18423074 missense possibly damaging 0.61
R1454:Psg28 UTSW 7 18427964 missense possibly damaging 0.50
R1725:Psg28 UTSW 7 18428011 missense possibly damaging 0.67
R2176:Psg28 UTSW 7 18427879 missense probably damaging 1.00
R3154:Psg28 UTSW 7 18426423 missense possibly damaging 0.91
R4520:Psg28 UTSW 7 18422901 missense probably benign 0.00
R5010:Psg28 UTSW 7 18427891 missense probably damaging 1.00
R5529:Psg28 UTSW 7 18430448 missense probably benign 0.15
R5772:Psg28 UTSW 7 18430715 missense probably damaging 1.00
R6039:Psg28 UTSW 7 18426182 missense possibly damaging 0.82
R6039:Psg28 UTSW 7 18426182 missense possibly damaging 0.82
R6046:Psg28 UTSW 7 18426380 missense probably damaging 1.00
R6275:Psg28 UTSW 7 18430440 missense probably damaging 1.00
R6586:Psg28 UTSW 7 18430544 missense probably damaging 0.99
R6928:Psg28 UTSW 7 18423078 missense possibly damaging 0.80
R7197:Psg28 UTSW 7 18430584 missense probably damaging 1.00
R7237:Psg28 UTSW 7 18427844 missense possibly damaging 0.65
R7859:Psg28 UTSW 7 18426224 missense probably damaging 1.00
R7863:Psg28 UTSW 7 18428117 missense possibly damaging 0.62
R7993:Psg28 UTSW 7 18426476 missense possibly damaging 0.63
R8009:Psg28 UTSW 7 18422997 missense probably damaging 0.96
R8115:Psg28 UTSW 7 18430386 missense probably benign 0.15
R8247:Psg28 UTSW 7 18422939 missense probably benign 0.01
RF016:Psg28 UTSW 7 18422922 missense probably damaging 0.97
X0020:Psg28 UTSW 7 18427939 missense possibly damaging 0.95
Posted On2013-12-09