Incidental Mutation 'IGL01631:Tsga13'
ID93443
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tsga13
Ensembl Gene ENSMUSG00000039032
Gene Nametestis specific gene A13
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.147) question?
Stock #IGL01631
Quality Score
Status
Chromosome6
Chromosomal Location30896981-30915573 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 30913566 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Glutamic Acid at position 8 (K8E)
Ref Sequence ENSEMBL: ENSMUSP00000040894 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000048580]
Predicted Effect possibly damaging
Transcript: ENSMUST00000048580
AA Change: K8E

PolyPhen 2 Score 0.470 (Sensitivity: 0.89; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000040894
Gene: ENSMUSG00000039032
AA Change: K8E

DomainStartEndE-ValueType
Pfam:TSGA13 3 271 9.5e-125 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000139006
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4931408C20Rik T C 1: 26,685,414 I228M probably damaging Het
Apip C A 2: 103,073,849 probably benign Het
Arid4a C T 12: 71,022,262 probably benign Het
Brwd1 C A 16: 96,046,466 E98D probably damaging Het
Cactin A G 10: 81,323,224 E303G probably benign Het
Ccdc181 T A 1: 164,280,144 I132K possibly damaging Het
Celsr3 A G 9: 108,837,404 H1995R probably benign Het
Cog4 A G 8: 110,881,840 E756G probably damaging Het
Ctsf T C 19: 4,858,078 L217P probably damaging Het
Dmp1 G T 5: 104,212,868 R470L probably benign Het
Dnajc9 T C 14: 20,388,108 D142G probably benign Het
Ednrb T A 14: 103,843,225 R84S probably benign Het
Gm1110 A T 9: 26,897,916 probably null Het
Gm13119 A G 4: 144,362,445 H111R probably benign Het
Has2 A G 15: 56,681,676 S177P possibly damaging Het
Herc6 C T 6: 57,604,107 S264F probably benign Het
Il1rl2 T A 1: 40,356,814 probably null Het
Ltbp2 A G 12: 84,809,146 probably null Het
Map4 A G 9: 110,063,133 probably benign Het
March4 T A 1: 72,452,531 K194* probably null Het
Megf10 A G 18: 57,259,797 D422G possibly damaging Het
Mfsd2a C A 4: 122,949,307 A394S probably benign Het
Mmp27 T C 9: 7,573,288 probably benign Het
Mvd A G 8: 122,434,821 Y370H possibly damaging Het
Olfr1254 T C 2: 89,788,785 D189G probably damaging Het
Olfr922 T A 9: 38,816,039 C179S probably damaging Het
Ptk2 G A 15: 73,216,371 H859Y probably damaging Het
Ptprq T A 10: 107,643,538 E1209D probably benign Het
Rhot1 C T 11: 80,265,774 T636M probably damaging Het
Ripk2 C A 4: 16,163,342 A19S possibly damaging Het
Rsbn1l G A 5: 20,896,571 S657L probably damaging Het
Rsbn1l A T 5: 20,896,572 S657T probably damaging Het
Sema6c A G 3: 95,170,403 T450A probably benign Het
Slc25a1 C T 16: 17,926,066 C262Y probably damaging Het
Slfn3 T C 11: 83,213,535 S288P probably damaging Het
Snrnp200 T A 2: 127,238,824 probably benign Het
Ssu2 T C 6: 112,374,882 Y294C probably damaging Het
Terb1 A G 8: 104,472,864 S483P probably damaging Het
Zbbx T G 3: 75,078,677 D351A probably damaging Het
Zfp454 G T 11: 50,883,735 A37D probably benign Het
Other mutations in Tsga13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02487:Tsga13 APN 6 30907427 missense probably damaging 1.00
IGL02602:Tsga13 APN 6 30902277 missense possibly damaging 0.92
R3894:Tsga13 UTSW 6 30912263 missense probably benign
R4335:Tsga13 UTSW 6 30900045 missense probably damaging 0.97
R4582:Tsga13 UTSW 6 30902363 missense probably benign 0.04
R5705:Tsga13 UTSW 6 30900016 missense probably damaging 1.00
R6248:Tsga13 UTSW 6 30897204 missense probably benign 0.01
R7470:Tsga13 UTSW 6 30900046 missense possibly damaging 0.70
Posted On2013-12-09