Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01634:Myo15a'

93558

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Myo15a

Ensembl Gene

ENSMUSG00000042678

Gene Name

myosin XVA

Synonyms

Myo15

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01634

Quality Score

Status

Chromosome

Chromosomal Location

60360165-60419195 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 60386298 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1808 (T1808A)

Ref Sequence

ENSEMBL: ENSMUSP00000091686 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071880] [ENSMUST00000081823] [ENSMUST00000094135]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000071880
AA Change: T1808A

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000071777
Gene: ENSMUSG00000042678
AA Change: T1808A

Domain	Start	End	E-Value	Type
low complexity region	4	24	N/A	INTRINSIC
low complexity region	87	100	N/A	INTRINSIC
low complexity region	107	120	N/A	INTRINSIC
low complexity region	269	292	N/A	INTRINSIC
low complexity region	295	306	N/A	INTRINSIC
low complexity region	311	325	N/A	INTRINSIC
low complexity region	349	384	N/A	INTRINSIC
low complexity region	425	435	N/A	INTRINSIC
low complexity region	487	498	N/A	INTRINSIC
low complexity region	502	509	N/A	INTRINSIC
low complexity region	653	681	N/A	INTRINSIC
low complexity region	692	705	N/A	INTRINSIC
low complexity region	737	747	N/A	INTRINSIC
low complexity region	758	775	N/A	INTRINSIC
low complexity region	781	792	N/A	INTRINSIC
low complexity region	796	809	N/A	INTRINSIC
low complexity region	825	849	N/A	INTRINSIC
low complexity region	883	897	N/A	INTRINSIC
low complexity region	1067	1082	N/A	INTRINSIC
low complexity region	1115	1130	N/A	INTRINSIC
MYSc	1200	1884	N/A	SMART
IQ	1885	1907	1.63e-1	SMART
IQ	1908	1930	1.77e-2	SMART
IQ	1931	1953	2.97e2	SMART
low complexity region	1955	1974	N/A	INTRINSIC
low complexity region	1992	2006	N/A	INTRINSIC
MyTH4	2049	2195	1.8e-42	SMART
low complexity region	2396	2405	N/A	INTRINSIC
low complexity region	2451	2461	N/A	INTRINSIC
Blast:MYSc	2665	2848	2e-14	BLAST
SH3	2851	2933	1.55e-4	SMART
low complexity region	2949	2962	N/A	INTRINSIC
MyTH4	3031	3185	5.59e-48	SMART
B41	3188	3400	6.94e-3	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000081823
AA Change: T621A

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000080507
Gene: ENSMUSG00000042678
AA Change: T621A

Domain	Start	End	E-Value	Type
MYSc	13	697	N/A	SMART
IQ	698	720	1.63e-1	SMART
IQ	721	743	1.77e-2	SMART
IQ	744	766	2.97e2	SMART
low complexity region	787	801	N/A	INTRINSIC
MyTH4	844	990	1.8e-42	SMART
low complexity region	1191	1200	N/A	INTRINSIC
low complexity region	1246	1256	N/A	INTRINSIC
Blast:MYSc	1460	1643	7e-15	BLAST
SH3	1646	1728	1.55e-4	SMART
low complexity region	1744	1757	N/A	INTRINSIC
MyTH4	1826	1980	5.59e-48	SMART
B41	1983	2195	6.94e-3	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000094135
AA Change: T1808A

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000091686
Gene: ENSMUSG00000042678
AA Change: T1808A

Domain	Start	End	E-Value	Type
low complexity region	4	24	N/A	INTRINSIC
low complexity region	87	100	N/A	INTRINSIC
low complexity region	107	120	N/A	INTRINSIC
low complexity region	269	292	N/A	INTRINSIC
low complexity region	295	306	N/A	INTRINSIC
low complexity region	311	325	N/A	INTRINSIC
low complexity region	349	384	N/A	INTRINSIC
low complexity region	425	435	N/A	INTRINSIC
low complexity region	487	498	N/A	INTRINSIC
low complexity region	502	509	N/A	INTRINSIC
low complexity region	653	681	N/A	INTRINSIC
low complexity region	692	705	N/A	INTRINSIC
low complexity region	737	747	N/A	INTRINSIC
low complexity region	758	775	N/A	INTRINSIC
low complexity region	781	792	N/A	INTRINSIC
low complexity region	796	809	N/A	INTRINSIC
low complexity region	825	849	N/A	INTRINSIC
low complexity region	883	897	N/A	INTRINSIC
low complexity region	1067	1082	N/A	INTRINSIC
low complexity region	1115	1130	N/A	INTRINSIC
MYSc	1200	1884	N/A	SMART
IQ	1885	1907	1.63e-1	SMART
IQ	1908	1930	1.77e-2	SMART
IQ	1931	1953	2.97e2	SMART
low complexity region	1974	1988	N/A	INTRINSIC
MyTH4	2031	2177	1.8e-42	SMART
low complexity region	2378	2387	N/A	INTRINSIC
low complexity region	2433	2443	N/A	INTRINSIC
Blast:MYSc	2647	2830	2e-14	BLAST
SH3	2833	2915	1.55e-4	SMART
low complexity region	2931	2944	N/A	INTRINSIC
MyTH4	3013	3167	5.59e-48	SMART
B41	3170	3382	6.94e-3	SMART

Predicted Effect

unknown
Transcript: ENSMUST00000126522
AA Change: T639A

SMART Domains

Protein: ENSMUSP00000120839
Gene: ENSMUSG00000042678
AA Change: T639A

Domain	Start	End	E-Value	Type
MYSc	34	716	N/A	SMART
IQ	717	739	1.63e-1	SMART
IQ	740	762	1.77e-2	SMART
IQ	763	785	2.97e2	SMART
low complexity region	806	820	N/A	INTRINSIC
MyTH4	863	1009	1.8e-42	SMART
low complexity region	1210	1219	N/A	INTRINSIC
low complexity region	1265	1275	N/A	INTRINSIC
Blast:MYSc	1479	1662	5e-15	BLAST
SH3	1665	1747	1.55e-4	SMART
low complexity region	1763	1776	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mutations in this gene result in profound deafness and neurological behavior. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 64 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700034H15Rik	A	T	1: 191,633,016 (GRCm39)		noncoding transcript	Het
4933421I07Rik	C	T	7: 42,097,123 (GRCm39)	D63N	probably benign	Het
Alg9	C	A	9: 50,686,677 (GRCm39)		probably null	Het
Anln	T	C	9: 22,271,771 (GRCm39)	T695A	probably benign	Het
Aox4	G	T	1: 58,261,089 (GRCm39)	D141Y	possibly damaging	Het
Arhgap21	C	A	2: 20,919,455 (GRCm39)	Q84H	probably benign	Het
Arnt	G	A	3: 95,377,709 (GRCm39)		probably benign	Het
Atp8a2	T	A	14: 60,235,511 (GRCm39)	Y677F	probably benign	Het
Car6	C	T	4: 150,282,610 (GRCm39)	V12M	probably benign	Het
Cd209d	A	T	8: 3,927,974 (GRCm39)		probably null	Het
Ctnna1	T	A	18: 35,356,501 (GRCm39)	V390E	probably damaging	Het
Cypt4	T	A	9: 24,536,952 (GRCm39)	N147K	possibly damaging	Het
Dnah10	C	A	5: 124,898,405 (GRCm39)	A3729E	probably damaging	Het
Dusp8	A	G	7: 141,638,160 (GRCm39)	V156A	probably benign	Het
Ecm1	G	A	3: 95,642,211 (GRCm39)	P458L	probably damaging	Het
Fat3	T	G	9: 15,909,654 (GRCm39)	Y2116S	probably damaging	Het
Fscn3	T	A	6: 28,430,537 (GRCm39)	Y236N	probably damaging	Het
Gaa	G	A	11: 119,164,902 (GRCm39)	S265N	possibly damaging	Het
Gas7	T	C	11: 67,565,057 (GRCm39)		probably benign	Het
Gbp8	T	C	5: 105,166,438 (GRCm39)	K297R	probably damaging	Het
Gm1818	G	A	12: 48,602,992 (GRCm39)		noncoding transcript	Het
Gm5114	G	T	7: 39,058,071 (GRCm39)	T516K	probably benign	Het
Hectd1	A	G	12: 51,850,562 (GRCm39)	S165P	probably damaging	Het
Hoxb4	G	T	11: 96,209,726 (GRCm39)	R44L	probably damaging	Het
Ivd	G	A	2: 118,706,863 (GRCm39)	R285H	probably damaging	Het
Krtap20-2	T	C	16: 89,002,977 (GRCm39)	F59S	unknown	Het
Megf8	G	A	7: 25,058,206 (GRCm39)		probably benign	Het
Mgat4d	A	T	8: 84,094,745 (GRCm39)	M261L	possibly damaging	Het
Mlc1	A	T	15: 88,858,921 (GRCm39)		probably benign	Het
Mmp20	T	A	9: 7,635,149 (GRCm39)	Y43*	probably null	Het
Morc3	G	A	16: 93,670,125 (GRCm39)	V767I	probably benign	Het
Notch4	T	C	17: 34,791,562 (GRCm39)	F574L	probably damaging	Het
Npas3	G	A	12: 53,993,946 (GRCm39)	V164M	probably damaging	Het
Nptx1	A	G	11: 119,435,498 (GRCm39)	Y273H	probably damaging	Het
Oaf	T	C	9: 43,135,301 (GRCm39)	N159S	probably damaging	Het
Or10a3n	A	T	7: 108,493,292 (GRCm39)	F107L	probably benign	Het
Or4c111	T	A	2: 88,843,788 (GRCm39)	I207F	probably damaging	Het
Or5ak24	A	T	2: 85,260,783 (GRCm39)	L130H	probably damaging	Het
Pgm2	T	C	5: 64,258,317 (GRCm39)	F101L	probably benign	Het
Pkd1l3	A	C	8: 110,394,157 (GRCm39)		probably null	Het
Plcd1	C	T	9: 118,902,857 (GRCm39)	R527H	probably damaging	Het
Rexo2	C	T	9: 48,380,215 (GRCm39)	E206K	probably damaging	Het
Ropn1	C	A	16: 34,487,148 (GRCm39)	T28N	possibly damaging	Het
Ropn1	A	T	16: 34,487,141 (GRCm39)	I26F	probably damaging	Het
Rpgrip1l	C	A	8: 91,979,171 (GRCm39)	S998I	probably benign	Het
Rpgrip1l	T	A	8: 91,979,172 (GRCm39)	S998C	probably benign	Het
Scap	T	C	9: 110,207,857 (GRCm39)		probably null	Het
Sec23b	T	C	2: 144,401,150 (GRCm39)	Y4H	probably damaging	Het
Sfrp4	C	A	13: 19,807,800 (GRCm39)	D66E	possibly damaging	Het
Slc25a36	T	C	9: 96,962,534 (GRCm39)	T13A	probably benign	Het
Synpr	A	T	14: 13,608,576 (GRCm38)	I119F	possibly damaging	Het
Tamm41	A	C	6: 114,993,059 (GRCm39)	H109Q	probably benign	Het
Tet1	A	T	10: 62,714,367 (GRCm39)	I476K	possibly damaging	Het
Tg	A	T	15: 66,601,415 (GRCm39)	I142F	probably benign	Het
Thada	A	T	17: 84,700,786 (GRCm39)		probably null	Het
Triobp	T	C	15: 78,877,568 (GRCm39)	L1654P	probably damaging	Het
Trpm7	A	G	2: 126,668,738 (GRCm39)	V726A	probably damaging	Het
Txndc15	T	G	13: 55,869,438 (GRCm39)	V197G	probably damaging	Het
Ubr3	A	T	2: 69,803,916 (GRCm39)	T1169S	probably benign	Het
Uhmk1	C	T	1: 170,034,682 (GRCm39)		probably null	Het
Vmn2r16	T	A	5: 109,488,177 (GRCm39)	M350K	probably benign	Het
Vmn2r77	G	A	7: 86,460,857 (GRCm39)	V728I	probably benign	Het
Wipf1	G	A	2: 73,278,225 (GRCm39)	P7S	unknown	Het
Zswim3	A	G	2: 164,661,922 (GRCm39)	D134G	probably damaging	Het

Other mutations in Myo15a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00845:Myo15a	APN	11	60,368,605 (GRCm39)	missense	probably damaging	1.00
IGL01011:Myo15a	APN	11	60,367,818 (GRCm39)	missense	probably benign	0.33
IGL01100:Myo15a	APN	11	60,401,984 (GRCm39)	missense	probably damaging	1.00
IGL01357:Myo15a	APN	11	60,393,115 (GRCm39)	splice site	probably benign
IGL01763:Myo15a	APN	11	60,412,564 (GRCm39)	missense	probably benign	0.07
IGL01901:Myo15a	APN	11	60,418,260 (GRCm39)	utr 3 prime	probably benign
IGL01931:Myo15a	APN	11	60,386,964 (GRCm39)	missense	probably damaging	1.00
IGL02006:Myo15a	APN	11	60,401,954 (GRCm39)	missense	probably damaging	1.00
IGL02041:Myo15a	APN	11	60,397,689 (GRCm39)	missense	probably damaging	0.99
IGL02094:Myo15a	APN	11	60,401,473 (GRCm39)	unclassified	probably benign
IGL02122:Myo15a	APN	11	60,374,292 (GRCm39)	missense	probably benign	0.23
IGL02153:Myo15a	APN	11	60,389,223 (GRCm39)	missense	probably damaging	1.00
IGL02328:Myo15a	APN	11	60,417,433 (GRCm39)	missense	probably benign	0.13
IGL02330:Myo15a	APN	11	60,367,987 (GRCm39)	missense	possibly damaging	0.94
IGL02431:Myo15a	APN	11	60,401,465 (GRCm39)	missense	possibly damaging	0.73
IGL02639:Myo15a	APN	11	60,369,447 (GRCm39)	missense	probably benign
IGL02659:Myo15a	APN	11	60,382,609 (GRCm39)	splice site	probably benign
IGL02800:Myo15a	APN	11	60,393,195 (GRCm39)	missense	probably damaging	1.00
IGL02812:Myo15a	APN	11	60,368,005 (GRCm39)	missense	probably benign	0.15
IGL02863:Myo15a	APN	11	60,368,953 (GRCm39)	missense	probably damaging	1.00
IGL02873:Myo15a	APN	11	60,374,308 (GRCm39)	missense	probably damaging	1.00
IGL02990:Myo15a	APN	11	60,370,266 (GRCm39)	missense	probably benign	0.02
IGL03011:Myo15a	APN	11	60,400,357 (GRCm39)	splice site	probably benign
IGL03243:Myo15a	APN	11	60,387,344 (GRCm39)	missense	probably damaging	1.00
IGL03297:Myo15a	APN	11	60,369,967 (GRCm39)	missense	probably damaging	1.00
novichok	UTSW	11	60,372,566 (GRCm39)	critical splice donor site	probably null
parker	UTSW	11	60,411,740 (GRCm39)	critical splice donor site	probably null
Typhoon	UTSW	11	60,378,251 (GRCm39)	critical splice donor site	probably null
PIT4131001:Myo15a	UTSW	11	60,386,280 (GRCm39)	missense	probably damaging	1.00
PIT4131001:Myo15a	UTSW	11	60,373,953 (GRCm39)	missense	probably damaging	1.00
R0133:Myo15a	UTSW	11	60,368,676 (GRCm39)	missense	possibly damaging	0.94
R0265:Myo15a	UTSW	11	60,405,723 (GRCm39)	critical splice acceptor site	probably null
R0389:Myo15a	UTSW	11	60,369,364 (GRCm39)	missense	probably benign
R0416:Myo15a	UTSW	11	60,402,000 (GRCm39)	missense	probably damaging	1.00
R0449:Myo15a	UTSW	11	60,400,422 (GRCm39)	missense	possibly damaging	0.92
R0477:Myo15a	UTSW	11	60,411,740 (GRCm39)	critical splice donor site	probably null
R0543:Myo15a	UTSW	11	60,369,877 (GRCm39)	missense	probably benign
R0546:Myo15a	UTSW	11	60,397,139 (GRCm39)	missense	probably damaging	1.00
R0555:Myo15a	UTSW	11	60,412,464 (GRCm39)	missense	probably damaging	1.00
R0639:Myo15a	UTSW	11	60,370,162 (GRCm39)	missense	probably benign	0.12
R0723:Myo15a	UTSW	11	60,369,803 (GRCm39)	missense	possibly damaging	0.94
R0837:Myo15a	UTSW	11	60,378,077 (GRCm39)	missense	probably damaging	0.98
R0865:Myo15a	UTSW	11	60,382,514 (GRCm39)	missense	probably damaging	1.00
R0899:Myo15a	UTSW	11	60,368,011 (GRCm39)	missense	possibly damaging	0.87
R1022:Myo15a	UTSW	11	60,370,442 (GRCm39)	missense	probably benign	0.00
R1024:Myo15a	UTSW	11	60,370,442 (GRCm39)	missense	probably benign	0.00
R1035:Myo15a	UTSW	11	60,401,384 (GRCm39)	unclassified	probably benign
R1109:Myo15a	UTSW	11	60,383,892 (GRCm39)	missense	probably damaging	1.00
R1170:Myo15a	UTSW	11	60,370,233 (GRCm39)	missense	probably benign	0.04
R1241:Myo15a	UTSW	11	60,390,256 (GRCm39)	missense	possibly damaging	0.58
R1392:Myo15a	UTSW	11	60,368,800 (GRCm39)	missense	possibly damaging	0.95
R1392:Myo15a	UTSW	11	60,368,800 (GRCm39)	missense	possibly damaging	0.95
R1434:Myo15a	UTSW	11	60,395,157 (GRCm39)	missense	probably benign	0.00
R1450:Myo15a	UTSW	11	60,386,308 (GRCm39)	missense	probably damaging	1.00
R1456:Myo15a	UTSW	11	60,399,028 (GRCm39)	missense	probably damaging	1.00
R1468:Myo15a	UTSW	11	60,396,832 (GRCm39)	missense	probably damaging	1.00
R1468:Myo15a	UTSW	11	60,396,832 (GRCm39)	missense	probably damaging	1.00
R1548:Myo15a	UTSW	11	60,379,064 (GRCm39)	missense	probably damaging	1.00
R1551:Myo15a	UTSW	11	60,383,791 (GRCm39)	missense	possibly damaging	0.70
R1571:Myo15a	UTSW	11	60,409,290 (GRCm39)	missense	probably damaging	1.00
R1662:Myo15a	UTSW	11	60,392,527 (GRCm39)	missense	probably damaging	1.00
R1777:Myo15a	UTSW	11	60,405,762 (GRCm39)	missense	probably benign
R1778:Myo15a	UTSW	11	60,369,238 (GRCm39)	missense	possibly damaging	0.57
R1847:Myo15a	UTSW	11	60,390,321 (GRCm39)	nonsense	probably null
R1875:Myo15a	UTSW	11	60,398,354 (GRCm39)	missense	probably damaging	0.99
R1944:Myo15a	UTSW	11	60,392,909 (GRCm39)	missense	probably damaging	0.99
R1945:Myo15a	UTSW	11	60,392,909 (GRCm39)	missense	probably damaging	0.99
R2013:Myo15a	UTSW	11	60,385,057 (GRCm39)	missense	probably damaging	1.00
R2107:Myo15a	UTSW	11	60,382,636 (GRCm39)	missense	probably damaging	1.00
R2108:Myo15a	UTSW	11	60,382,636 (GRCm39)	missense	probably damaging	1.00
R2112:Myo15a	UTSW	11	60,384,994 (GRCm39)	missense	probably damaging	0.99
R2147:Myo15a	UTSW	11	60,401,055 (GRCm39)	missense	possibly damaging	0.66
R2196:Myo15a	UTSW	11	60,400,847 (GRCm39)	nonsense	probably null
R2207:Myo15a	UTSW	11	60,396,860 (GRCm39)	missense	probably benign	0.01
R2245:Myo15a	UTSW	11	60,399,925 (GRCm39)	missense	probably damaging	1.00
R2367:Myo15a	UTSW	11	60,408,064 (GRCm39)	missense	probably damaging	0.99
R2374:Myo15a	UTSW	11	60,369,669 (GRCm39)	missense	possibly damaging	0.88
R2438:Myo15a	UTSW	11	60,373,878 (GRCm39)	missense	probably damaging	1.00
R3154:Myo15a	UTSW	11	60,370,186 (GRCm39)	splice site	probably null
R3423:Myo15a	UTSW	11	60,401,126 (GRCm39)	critical splice donor site	probably null
R3551:Myo15a	UTSW	11	60,400,489 (GRCm39)	missense	possibly damaging	0.93
R3552:Myo15a	UTSW	11	60,400,489 (GRCm39)	missense	possibly damaging	0.93
R3612:Myo15a	UTSW	11	60,368,505 (GRCm39)	missense	probably damaging	1.00
R3620:Myo15a	UTSW	11	60,369,468 (GRCm39)	missense	possibly damaging	0.63
R3713:Myo15a	UTSW	11	60,370,057 (GRCm39)	missense	possibly damaging	0.55
R3714:Myo15a	UTSW	11	60,370,057 (GRCm39)	missense	possibly damaging	0.55
R3715:Myo15a	UTSW	11	60,370,057 (GRCm39)	missense	possibly damaging	0.55
R3783:Myo15a	UTSW	11	60,368,398 (GRCm39)	missense	probably damaging	0.97
R3784:Myo15a	UTSW	11	60,368,398 (GRCm39)	missense	probably damaging	0.97
R3785:Myo15a	UTSW	11	60,368,398 (GRCm39)	missense	probably damaging	0.97
R3786:Myo15a	UTSW	11	60,368,398 (GRCm39)	missense	probably damaging	0.97
R3787:Myo15a	UTSW	11	60,368,398 (GRCm39)	missense	probably damaging	0.97
R3894:Myo15a	UTSW	11	60,395,145 (GRCm39)	missense	probably benign	0.00
R3962:Myo15a	UTSW	11	60,370,654 (GRCm39)	missense	probably benign	0.00
R4082:Myo15a	UTSW	11	60,378,022 (GRCm39)	missense	possibly damaging	0.92
R4555:Myo15a	UTSW	11	60,387,763 (GRCm39)	missense	probably damaging	1.00
R4641:Myo15a	UTSW	11	60,393,867 (GRCm39)	missense	probably damaging	1.00
R4665:Myo15a	UTSW	11	60,395,705 (GRCm39)	critical splice acceptor site	probably null
R4713:Myo15a	UTSW	11	60,370,756 (GRCm39)	missense	probably benign	0.21
R4820:Myo15a	UTSW	11	60,367,741 (GRCm39)	missense	probably damaging	0.98
R5013:Myo15a	UTSW	11	60,382,493 (GRCm39)	missense	probably damaging	1.00
R5051:Myo15a	UTSW	11	60,378,251 (GRCm39)	critical splice donor site	probably null
R5187:Myo15a	UTSW	11	60,394,440 (GRCm39)	missense	probably damaging	1.00
R5230:Myo15a	UTSW	11	60,393,674 (GRCm39)	missense	possibly damaging	0.68
R5277:Myo15a	UTSW	11	60,367,940 (GRCm39)	nonsense	probably null
R5345:Myo15a	UTSW	11	60,388,364 (GRCm39)	missense	probably damaging	0.99
R5349:Myo15a	UTSW	11	60,384,409 (GRCm39)	missense	probably damaging	1.00
R5356:Myo15a	UTSW	11	60,389,192 (GRCm39)	missense	probably damaging	1.00
R5445:Myo15a	UTSW	11	60,411,603 (GRCm39)	nonsense	probably null
R5477:Myo15a	UTSW	11	60,368,503 (GRCm39)	missense	probably damaging	1.00
R5629:Myo15a	UTSW	11	60,370,578 (GRCm39)	missense	probably benign
R5728:Myo15a	UTSW	11	60,379,722 (GRCm39)	missense	probably damaging	1.00
R5818:Myo15a	UTSW	11	60,388,777 (GRCm39)	missense	probably benign	0.06
R5952:Myo15a	UTSW	11	60,370,246 (GRCm39)	missense	possibly damaging	0.50
R6338:Myo15a	UTSW	11	60,368,959 (GRCm39)	missense	probably damaging	0.99
R6467:Myo15a	UTSW	11	60,417,487 (GRCm39)	critical splice donor site	probably null
R6488:Myo15a	UTSW	11	60,369,313 (GRCm39)	missense	possibly damaging	0.86
R6521:Myo15a	UTSW	11	60,393,195 (GRCm39)	missense	probably damaging	1.00
R6645:Myo15a	UTSW	11	60,368,118 (GRCm39)	missense	probably benign	0.00
R6702:Myo15a	UTSW	11	60,383,818 (GRCm39)	missense	probably benign	0.16
R6703:Myo15a	UTSW	11	60,383,818 (GRCm39)	missense	probably benign	0.16
R6821:Myo15a	UTSW	11	60,415,301 (GRCm39)	missense	probably damaging	1.00
R6882:Myo15a	UTSW	11	60,414,832 (GRCm39)	missense	probably damaging	1.00
R6908:Myo15a	UTSW	11	60,396,832 (GRCm39)	missense	probably damaging	1.00
R6932:Myo15a	UTSW	11	60,390,320 (GRCm39)	missense	probably damaging	1.00
R6958:Myo15a	UTSW	11	60,394,451 (GRCm39)	missense	probably benign	0.07
R7041:Myo15a	UTSW	11	60,396,832 (GRCm39)	missense	probably damaging	1.00
R7149:Myo15a	UTSW	11	60,400,836 (GRCm39)	missense	possibly damaging	0.56
R7163:Myo15a	UTSW	11	60,389,195 (GRCm39)	missense
R7229:Myo15a	UTSW	11	60,387,321 (GRCm39)	missense	probably benign	0.08
R7347:Myo15a	UTSW	11	60,368,787 (GRCm39)	missense	probably benign
R7368:Myo15a	UTSW	11	60,381,741 (GRCm39)	splice site	probably null
R7392:Myo15a	UTSW	11	60,396,802 (GRCm39)	missense
R7414:Myo15a	UTSW	11	60,374,309 (GRCm39)	missense
R7461:Myo15a	UTSW	11	60,395,978 (GRCm39)	missense
R7609:Myo15a	UTSW	11	60,379,637 (GRCm39)	missense
R7613:Myo15a	UTSW	11	60,395,978 (GRCm39)	missense
R7734:Myo15a	UTSW	11	60,401,108 (GRCm39)	missense	probably benign
R7748:Myo15a	UTSW	11	60,395,727 (GRCm39)	missense
R7767:Myo15a	UTSW	11	60,392,922 (GRCm39)	missense
R7769:Myo15a	UTSW	11	60,399,975 (GRCm39)	missense
R7894:Myo15a	UTSW	11	60,381,963 (GRCm39)	missense
R7919:Myo15a	UTSW	11	60,417,356 (GRCm39)	missense	probably damaging	1.00
R8100:Myo15a	UTSW	11	60,408,016 (GRCm39)	missense	probably damaging	1.00
R8124:Myo15a	UTSW	11	60,398,279 (GRCm39)	missense
R8129:Myo15a	UTSW	11	60,399,026 (GRCm39)	missense
R8428:Myo15a	UTSW	11	60,387,241 (GRCm39)	missense	probably damaging	1.00
R8706:Myo15a	UTSW	11	60,370,443 (GRCm39)	missense	probably benign
R8735:Myo15a	UTSW	11	60,401,679 (GRCm39)	critical splice acceptor site	probably null
R8739:Myo15a	UTSW	11	60,368,088 (GRCm39)	missense	probably benign	0.06
R8790:Myo15a	UTSW	11	60,378,047 (GRCm39)	missense
R8790:Myo15a	UTSW	11	60,367,362 (GRCm39)	missense	possibly damaging	0.73
R8822:Myo15a	UTSW	11	60,367,740 (GRCm39)	missense	probably damaging	0.99
R8907:Myo15a	UTSW	11	60,417,434 (GRCm39)	missense
R8931:Myo15a	UTSW	11	60,368,020 (GRCm39)	missense	probably benign
R9061:Myo15a	UTSW	11	60,393,692 (GRCm39)	missense
R9124:Myo15a	UTSW	11	60,369,952 (GRCm39)	missense	probably benign	0.37
R9297:Myo15a	UTSW	11	60,385,899 (GRCm39)	missense	probably null
R9347:Myo15a	UTSW	11	60,374,555 (GRCm39)	missense
R9417:Myo15a	UTSW	11	60,378,243 (GRCm39)	missense
R9456:Myo15a	UTSW	11	60,392,668 (GRCm39)	missense
R9460:Myo15a	UTSW	11	60,372,566 (GRCm39)	critical splice donor site	probably null
R9615:Myo15a	UTSW	11	60,374,320 (GRCm39)	missense
R9630:Myo15a	UTSW	11	60,407,988 (GRCm39)	missense	probably damaging	1.00
R9746:Myo15a	UTSW	11	60,378,234 (GRCm39)	nonsense	probably null
X0021:Myo15a	UTSW	11	60,373,185 (GRCm39)	nonsense	probably null
X0066:Myo15a	UTSW	11	60,369,046 (GRCm39)	missense	probably damaging	1.00
X0067:Myo15a	UTSW	11	60,369,444 (GRCm39)	missense	possibly damaging	0.88
Z1176:Myo15a	UTSW	11	60,389,229 (GRCm39)	missense
Z1176:Myo15a	UTSW	11	60,379,084 (GRCm39)	missense
Z1176:Myo15a	UTSW	11	60,415,267 (GRCm39)	missense	probably damaging	1.00
Z1177:Myo15a	UTSW	11	60,386,301 (GRCm39)	missense
Z1177:Myo15a	UTSW	11	60,379,663 (GRCm39)	missense
Z1177:Myo15a	UTSW	11	60,368,349 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-12-09