Mutagenetix > Incidental Mutation

Incidental Mutation 'R1110:Prune2'

96724

Institutional Source

Beutler Lab

Gene Symbol

Prune2

Ensembl Gene

ENSMUSG00000039126

Gene Name

prune homolog 2

Synonyms

A230083H22Rik, 6330414G02Rik, A330102H22Rik

MMRRC Submission

039183-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1110 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

16956118-17223932 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 17125222 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 2582 (S2582P)

Ref Sequence

ENSEMBL: ENSMUSP00000084977 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000087689]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000087689
AA Change: S2582P

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000084977
Gene: ENSMUSG00000039126
AA Change: S2582P

Domain	Start	End	E-Value	Type
DHHA2	208	351	8.32e-17	SMART
low complexity region	433	445	N/A	INTRINSIC
low complexity region	476	488	N/A	INTRINSIC
low complexity region	547	553	N/A	INTRINSIC
low complexity region	962	975	N/A	INTRINSIC
low complexity region	1071	1082	N/A	INTRINSIC
low complexity region	1368	1378	N/A	INTRINSIC
low complexity region	1533	1545	N/A	INTRINSIC
low complexity region	1668	1685	N/A	INTRINSIC
low complexity region	1740	1751	N/A	INTRINSIC
low complexity region	2162	2175	N/A	INTRINSIC
low complexity region	2222	2233	N/A	INTRINSIC
low complexity region	2591	2606	N/A	INTRINSIC
low complexity region	2731	2744	N/A	INTRINSIC
SEC14	2882	3037	2.08e-12	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000226052

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.7%
20x: 94.3%

Validation Efficiency

97% (63/65)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Allele List at MGI

All alleles(160) : Gene trapped(160)

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acap3	T	A	4: 155,905,399 (GRCm38)		probably null	Het
Acp2	A	G	2: 91,208,422 (GRCm38)		probably null	Het
Akap13	T	G	7: 75,611,377 (GRCm38)	S447A	possibly damaging	Het
Alk	G	A	17: 71,984,745 (GRCm38)		probably benign	Het
Arhgef39	T	C	4: 43,496,834 (GRCm38)	T327A	probably benign	Het
Cdan1	G	A	2: 120,720,602 (GRCm38)	A1103V	probably damaging	Het
Cdh18	A	G	15: 23,474,317 (GRCm38)	T758A	probably benign	Het
Cdk17	T	A	10: 93,239,033 (GRCm38)	Y3*	probably null	Het
Cdon	T	C	9: 35,456,437 (GRCm38)		probably benign	Het
Cntn3	T	A	6: 102,245,158 (GRCm38)	N460I	probably benign	Het
Cntrl	T	A	2: 35,160,627 (GRCm38)	C985S	possibly damaging	Het
Col6a2	T	C	10: 76,607,740 (GRCm38)	E497G	probably benign	Het
Crybg1	A	G	10: 43,999,093 (GRCm38)	M673T	possibly damaging	Het
Cyp2u1	A	G	3: 131,293,609 (GRCm38)	I441T	possibly damaging	Het
Disp2	T	C	2: 118,790,439 (GRCm38)	S551P	probably damaging	Het
Dock2	A	T	11: 34,256,535 (GRCm38)	F1354I	possibly damaging	Het
Dstyk	A	G	1: 132,453,325 (GRCm38)		probably benign	Het
Dzip1	T	C	14: 118,889,305 (GRCm38)	N527S	probably benign	Het
Eomes	A	G	9: 118,484,599 (GRCm38)	I571V	probably benign	Het
Fam26e	T	G	10: 34,096,017 (GRCm38)	I141L	probably benign	Het
Fbxl13	T	C	5: 21,484,036 (GRCm38)	D758G	probably benign	Het
Frem1	T	C	4: 82,950,320 (GRCm38)	S1457G	probably damaging	Het
Gabbr2	C	T	4: 46,718,838 (GRCm38)	C613Y	probably damaging	Het
Gm906	A	T	13: 50,248,260 (GRCm38)	D83E	possibly damaging	Het
Gm9755	A	T	8: 67,515,058 (GRCm38)		noncoding transcript	Het
Hnrnpul2	A	G	19: 8,826,746 (GRCm38)	R570G	probably damaging	Het
Igdcc4	A	G	9: 65,126,926 (GRCm38)	H674R	possibly damaging	Het
Kdm5d	T	A	Y: 910,539 (GRCm38)	L250H	probably damaging	Het
Kif1a	T	C	1: 93,023,453 (GRCm38)		probably benign	Het
Kmt2c	T	C	5: 25,314,362 (GRCm38)	N2250S	probably benign	Het
Kmt2e	C	T	5: 23,502,655 (GRCm38)	H1739Y	probably damaging	Het
Lmtk3	T	A	7: 45,795,003 (GRCm38)		probably benign	Het
Lpin3	A	G	2: 160,894,079 (GRCm38)	D93G	probably benign	Het
Myh10	T	C	11: 68,791,850 (GRCm38)		probably benign	Het
Myom2	G	A	8: 15,122,413 (GRCm38)	E1171K	probably benign	Het
Ncoa6	A	T	2: 155,411,520 (GRCm38)		probably benign	Het
Nup160	A	G	2: 90,733,219 (GRCm38)		probably benign	Het
Oit3	G	A	10: 59,428,194 (GRCm38)	R373C	probably damaging	Het
Olfml2a	A	T	2: 38,959,753 (GRCm38)	I494L	probably damaging	Het
Olfr743	T	C	14: 50,533,702 (GRCm38)	S97P	possibly damaging	Het
Olfr824	A	G	10: 130,126,653 (GRCm38)	Y135H	probably damaging	Het
Parp6	G	T	9: 59,649,564 (GRCm38)	C584F	probably damaging	Het
Pcgf2	A	G	11: 97,691,850 (GRCm38)		probably benign	Het
Pde3a	T	C	6: 141,459,316 (GRCm38)		probably benign	Het
Pibf1	C	T	14: 99,112,973 (GRCm38)	R186C	probably damaging	Het
Pitrm1	A	G	13: 6,558,244 (GRCm38)	D335G	probably benign	Het
Pkp4	T	C	2: 59,338,765 (GRCm38)	L752P	probably damaging	Het
Plcb3	C	A	19: 6,961,913 (GRCm38)	E566*	probably null	Het
Reln	A	T	5: 22,034,775 (GRCm38)	D831E	probably benign	Het
Samd9l	T	A	6: 3,374,267 (GRCm38)	D998V	probably benign	Het
Sardh	G	A	2: 27,191,919 (GRCm38)	T865I	possibly damaging	Het
Setbp1	G	A	18: 78,857,860 (GRCm38)	T864I	probably damaging	Het
Slc9a1	T	A	4: 133,370,548 (GRCm38)	M2K	probably benign	Het
Sorbs2	A	G	8: 45,795,730 (GRCm38)	T593A	probably benign	Het
Svs5	A	T	2: 164,333,587 (GRCm38)	I120L	probably benign	Het
Tcl1b1	G	T	12: 105,159,815 (GRCm38)	V19F	probably damaging	Het
Ttc30a1	A	T	2: 75,979,976 (GRCm38)	C588S	probably damaging	Het
Urgcp	T	C	11: 5,716,004 (GRCm38)	N778S	probably benign	Het
Vnn1	A	T	10: 23,899,601 (GRCm38)	I250F	possibly damaging	Het
Xntrpc	A	G	7: 102,082,974 (GRCm38)	R365G	possibly damaging	Het
Zfp84	T	A	7: 29,771,372 (GRCm38)	M1K	probably null	Het
Zfyve26	G	A	12: 79,280,067 (GRCm38)	R761C	probably damaging	Het
Zp3r	A	G	1: 130,577,884 (GRCm38)		probably null	Het

Other mutations in Prune2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00234:Prune2	APN	19	17,168,344 (GRCm38)	critical splice donor site	probably null
IGL00848:Prune2	APN	19	17,119,118 (GRCm38)	missense	probably damaging	1.00
IGL00862:Prune2	APN	19	17,119,349 (GRCm38)	missense	probably benign	0.41
IGL00915:Prune2	APN	19	17,016,253 (GRCm38)	missense	probably damaging	1.00
IGL01084:Prune2	APN	19	17,118,209 (GRCm38)	missense	probably benign	0.19
IGL01109:Prune2	APN	19	17,123,879 (GRCm38)	missense	probably benign	0.03
IGL01372:Prune2	APN	19	17,125,069 (GRCm38)	missense	probably damaging	1.00
IGL01650:Prune2	APN	19	17,168,292 (GRCm38)	missense	possibly damaging	0.95
IGL01752:Prune2	APN	19	17,123,903 (GRCm38)	missense	possibly damaging	0.50
IGL01812:Prune2	APN	19	17,003,777 (GRCm38)	missense	possibly damaging	0.50
IGL01902:Prune2	APN	19	17,118,638 (GRCm38)	missense	probably benign	0.00
IGL02195:Prune2	APN	19	17,119,557 (GRCm38)	missense	probably benign	0.00
IGL02502:Prune2	APN	19	17,123,881 (GRCm38)	missense	probably benign	0.00
IGL02569:Prune2	APN	19	17,178,859 (GRCm38)	missense	probably damaging	0.99
IGL02693:Prune2	APN	19	17,124,491 (GRCm38)	missense	probably benign	0.03
IGL02737:Prune2	APN	19	17,193,411 (GRCm38)	nonsense	probably null
IGL02794:Prune2	APN	19	17,119,361 (GRCm38)	missense	probably benign	0.19
IGL02985:Prune2	APN	19	17,016,359 (GRCm38)	critical splice donor site	probably null
IGL03349:Prune2	APN	19	17,123,346 (GRCm38)	missense	probably damaging	1.00
3-1:Prune2	UTSW	19	17,125,282 (GRCm38)	missense	probably benign	0.00
R0060:Prune2	UTSW	19	17,003,733 (GRCm38)	missense	probably damaging	1.00
R0098:Prune2	UTSW	19	17,123,903 (GRCm38)	missense	possibly damaging	0.50
R0098:Prune2	UTSW	19	17,123,903 (GRCm38)	missense	possibly damaging	0.50
R0165:Prune2	UTSW	19	17,122,610 (GRCm38)	missense	probably benign	0.00
R0277:Prune2	UTSW	19	17,121,389 (GRCm38)	missense	probably damaging	0.99
R0321:Prune2	UTSW	19	17,122,454 (GRCm38)	missense	probably benign	0.39
R0321:Prune2	UTSW	19	17,120,927 (GRCm38)	missense	possibly damaging	0.78
R0374:Prune2	UTSW	19	17,120,910 (GRCm38)	missense	probably benign	0.00
R0380:Prune2	UTSW	19	17,124,007 (GRCm38)	missense	probably damaging	1.00
R0396:Prune2	UTSW	19	17,123,080 (GRCm38)	missense	probably benign	0.35
R0408:Prune2	UTSW	19	17,122,310 (GRCm38)	missense	probably benign	0.00
R0421:Prune2	UTSW	19	17,123,311 (GRCm38)	missense	probably benign	0.02
R0480:Prune2	UTSW	19	17,006,792 (GRCm38)	splice site	probably benign
R0531:Prune2	UTSW	19	17,006,753 (GRCm38)	missense	probably damaging	1.00
R0546:Prune2	UTSW	19	17,020,666 (GRCm38)	splice site	probably benign
R0554:Prune2	UTSW	19	17,125,218 (GRCm38)	nonsense	probably null
R0659:Prune2	UTSW	19	17,122,835 (GRCm38)	missense	probably damaging	1.00
R0699:Prune2	UTSW	19	17,123,955 (GRCm38)	missense	probably damaging	1.00
R0781:Prune2	UTSW	19	17,125,222 (GRCm38)	missense	probably benign
R1178:Prune2	UTSW	19	17,123,105 (GRCm38)	missense	probably benign	0.22
R1181:Prune2	UTSW	19	17,123,105 (GRCm38)	missense	probably benign	0.22
R1337:Prune2	UTSW	19	17,119,607 (GRCm38)	missense	possibly damaging	0.70
R1356:Prune2	UTSW	19	17,212,317 (GRCm38)	missense	probably benign	0.40
R1385:Prune2	UTSW	19	17,124,948 (GRCm38)	missense	possibly damaging	0.50
R1659:Prune2	UTSW	19	17,120,651 (GRCm38)	missense	possibly damaging	0.59
R1738:Prune2	UTSW	19	17,125,010 (GRCm38)	missense	probably benign	0.01
R1756:Prune2	UTSW	19	17,123,704 (GRCm38)	missense	probably benign	0.01
R1765:Prune2	UTSW	19	17,125,598 (GRCm38)	missense	probably damaging	1.00
R1782:Prune2	UTSW	19	17,122,173 (GRCm38)	missense	probably benign	0.00
R1817:Prune2	UTSW	19	17,122,081 (GRCm38)	missense	probably benign	0.00
R1838:Prune2	UTSW	19	17,199,878 (GRCm38)	missense	probably damaging	1.00
R1851:Prune2	UTSW	19	17,199,139 (GRCm38)	missense	probably damaging	1.00
R1852:Prune2	UTSW	19	17,199,139 (GRCm38)	missense	probably damaging	1.00
R1866:Prune2	UTSW	19	17,123,492 (GRCm38)	missense	probably damaging	1.00
R1911:Prune2	UTSW	19	17,113,674 (GRCm38)	missense	probably benign	0.02
R1983:Prune2	UTSW	19	17,020,642 (GRCm38)	missense	probably damaging	0.97
R2014:Prune2	UTSW	19	17,120,523 (GRCm38)	missense	probably damaging	1.00
R2066:Prune2	UTSW	19	17,120,678 (GRCm38)	missense	possibly damaging	0.57
R2088:Prune2	UTSW	19	17,119,745 (GRCm38)	missense	possibly damaging	0.95
R2111:Prune2	UTSW	19	17,208,238 (GRCm38)	missense	probably damaging	1.00
R2128:Prune2	UTSW	19	17,122,422 (GRCm38)	missense	probably benign	0.00
R2165:Prune2	UTSW	19	17,120,182 (GRCm38)	missense	probably benign	0.19
R2241:Prune2	UTSW	19	17,123,092 (GRCm38)	missense	probably damaging	0.96
R2278:Prune2	UTSW	19	17,118,555 (GRCm38)	missense	possibly damaging	0.93
R2504:Prune2	UTSW	19	17,000,036 (GRCm38)	missense	probably damaging	1.00
R2508:Prune2	UTSW	19	17,122,622 (GRCm38)	missense	probably benign	0.43
R3055:Prune2	UTSW	19	17,125,043 (GRCm38)	missense	probably damaging	0.98
R3086:Prune2	UTSW	19	17,121,413 (GRCm38)	missense	possibly damaging	0.75
R3104:Prune2	UTSW	19	17,119,156 (GRCm38)	missense	probably damaging	1.00
R3105:Prune2	UTSW	19	17,119,156 (GRCm38)	missense	probably damaging	1.00
R3547:Prune2	UTSW	19	17,124,348 (GRCm38)	missense	probably damaging	0.96
R3702:Prune2	UTSW	19	17,178,871 (GRCm38)	missense	probably damaging	1.00
R3753:Prune2	UTSW	19	17,125,454 (GRCm38)	missense	probably benign	0.38
R3933:Prune2	UTSW	19	17,123,954 (GRCm38)	missense	probably damaging	1.00
R3935:Prune2	UTSW	19	17,199,786 (GRCm38)	missense	probably damaging	1.00
R4022:Prune2	UTSW	19	17,000,020 (GRCm38)	missense	probably damaging	1.00
R4042:Prune2	UTSW	19	17,003,826 (GRCm38)	critical splice donor site	probably null
R4164:Prune2	UTSW	19	17,003,734 (GRCm38)	missense	possibly damaging	0.87
R4453:Prune2	UTSW	19	17,121,910 (GRCm38)	missense	probably benign	0.00
R4642:Prune2	UTSW	19	17,020,655 (GRCm38)	critical splice donor site	probably null
R4661:Prune2	UTSW	19	17,000,023 (GRCm38)	missense	probably damaging	1.00
R4666:Prune2	UTSW	19	17,120,188 (GRCm38)	nonsense	probably null
R4823:Prune2	UTSW	19	17,120,504 (GRCm38)	missense	probably damaging	1.00
R4897:Prune2	UTSW	19	17,121,855 (GRCm38)	missense	probably benign	0.03
R4922:Prune2	UTSW	19	17,122,752 (GRCm38)	missense	probably benign	0.00
R4962:Prune2	UTSW	19	17,122,273 (GRCm38)	missense	probably benign	0.11
R5026:Prune2	UTSW	19	17,199,142 (GRCm38)	missense	probably damaging	1.00
R5042:Prune2	UTSW	19	17,119,797 (GRCm38)	missense	possibly damaging	0.94
R5124:Prune2	UTSW	19	17,199,910 (GRCm38)	missense	probably damaging	1.00
R5133:Prune2	UTSW	19	17,003,631 (GRCm38)	missense	probably damaging	1.00
R5184:Prune2	UTSW	19	17,216,357 (GRCm38)	missense	possibly damaging	0.95
R5234:Prune2	UTSW	19	17,118,668 (GRCm38)	missense	probably damaging	1.00
R5339:Prune2	UTSW	19	17,120,872 (GRCm38)	missense	probably damaging	1.00
R5363:Prune2	UTSW	19	17,118,266 (GRCm38)	missense	probably damaging	1.00
R5382:Prune2	UTSW	19	17,003,659 (GRCm38)	missense	probably damaging	1.00
R5436:Prune2	UTSW	19	17,020,643 (GRCm38)	missense	probably damaging	1.00
R5480:Prune2	UTSW	19	17,120,947 (GRCm38)	missense	possibly damaging	0.66
R5635:Prune2	UTSW	19	17,118,209 (GRCm38)	missense	probably benign	0.19
R5678:Prune2	UTSW	19	17,118,668 (GRCm38)	missense	probably damaging	1.00
R5814:Prune2	UTSW	19	17,016,361 (GRCm38)	splice site	probably null
R5894:Prune2	UTSW	19	17,121,391 (GRCm38)	missense	possibly damaging	0.88
R6011:Prune2	UTSW	19	17,118,716 (GRCm38)	missense	probably benign	0.35
R6207:Prune2	UTSW	19	17,118,116 (GRCm38)	missense	probably damaging	1.00
R6218:Prune2	UTSW	19	17,121,562 (GRCm38)	missense	probably benign	0.00
R6573:Prune2	UTSW	19	17,121,158 (GRCm38)	missense	possibly damaging	0.61
R6573:Prune2	UTSW	19	17,121,157 (GRCm38)	missense	probably damaging	1.00
R6734:Prune2	UTSW	19	17,003,733 (GRCm38)	missense	probably damaging	1.00
R6805:Prune2	UTSW	19	17,120,590 (GRCm38)	missense	probably benign
R6837:Prune2	UTSW	19	17,178,928 (GRCm38)	missense	probably damaging	1.00
R6850:Prune2	UTSW	19	17,122,188 (GRCm38)	missense	probably benign	0.00
R6858:Prune2	UTSW	19	17,118,106 (GRCm38)	missense	possibly damaging	0.70
R6874:Prune2	UTSW	19	17,123,228 (GRCm38)	missense	probably damaging	1.00
R6954:Prune2	UTSW	19	17,000,021 (GRCm38)	missense	probably damaging	1.00
R7098:Prune2	UTSW	19	17,120,602 (GRCm38)	missense	probably benign	0.39
R7102:Prune2	UTSW	19	17,121,213 (GRCm38)	missense	probably benign	0.24
R7246:Prune2	UTSW	19	17,121,368 (GRCm38)	missense	probably damaging	0.99
R7284:Prune2	UTSW	19	17,119,886 (GRCm38)	missense	probably damaging	1.00
R7295:Prune2	UTSW	19	17,119,897 (GRCm38)	missense	probably benign	0.01
R7371:Prune2	UTSW	19	17,119,370 (GRCm38)	missense	probably benign	0.02
R7651:Prune2	UTSW	19	17,120,408 (GRCm38)	missense	probably damaging	1.00
R7830:Prune2	UTSW	19	17,122,674 (GRCm38)	missense	probably benign	0.21
R7872:Prune2	UTSW	19	17,119,434 (GRCm38)	missense	probably benign	0.05
R7881:Prune2	UTSW	19	17,123,029 (GRCm38)	missense	possibly damaging	0.50
R7966:Prune2	UTSW	19	17,178,859 (GRCm38)	missense	probably damaging	0.99
R7969:Prune2	UTSW	19	17,201,670 (GRCm38)	missense	probably damaging	0.98
R8092:Prune2	UTSW	19	17,119,993 (GRCm38)	missense	probably damaging	1.00
R8110:Prune2	UTSW	19	17,120,719 (GRCm38)	missense	probably benign	0.22
R8115:Prune2	UTSW	19	17,123,924 (GRCm38)	missense	probably benign	0.02
R8129:Prune2	UTSW	19	17,118,836 (GRCm38)	missense	probably benign	0.01
R8169:Prune2	UTSW	19	17,125,091 (GRCm38)	missense	probably benign	0.10
R8171:Prune2	UTSW	19	17,120,518 (GRCm38)	missense	probably damaging	1.00
R8176:Prune2	UTSW	19	17,118,292 (GRCm38)	missense	probably damaging	1.00
R8200:Prune2	UTSW	19	17,124,973 (GRCm38)	missense	probably benign	0.01
R8217:Prune2	UTSW	19	17,120,116 (GRCm38)	missense	probably benign	0.01
R8258:Prune2	UTSW	19	17,212,308 (GRCm38)	missense	unknown
R8259:Prune2	UTSW	19	17,212,308 (GRCm38)	missense	unknown
R8289:Prune2	UTSW	19	17,123,009 (GRCm38)	missense	probably benign	0.43
R8329:Prune2	UTSW	19	17,121,265 (GRCm38)	missense	probably benign	0.02
R8342:Prune2	UTSW	19	17,125,663 (GRCm38)	missense	probably benign	0.01
R8558:Prune2	UTSW	19	17,122,238 (GRCm38)	missense	probably damaging	0.98
R8732:Prune2	UTSW	19	17,120,405 (GRCm38)	missense	probably damaging	1.00
R8743:Prune2	UTSW	19	17,119,556 (GRCm38)	missense	probably benign	0.22
R8769:Prune2	UTSW	19	17,123,078 (GRCm38)	missense	probably damaging	0.96
R8862:Prune2	UTSW	19	17,120,146 (GRCm38)	missense	probably benign	0.04
R8936:Prune2	UTSW	19	17,121,835 (GRCm38)	missense	probably benign	0.24
R9040:Prune2	UTSW	19	17,120,627 (GRCm38)	missense	probably damaging	1.00
R9084:Prune2	UTSW	19	17,120,377 (GRCm38)	missense	probably damaging	1.00
R9224:Prune2	UTSW	19	17,120,029 (GRCm38)	missense	probably damaging	1.00
R9273:Prune2	UTSW	19	17,118,326 (GRCm38)	missense	possibly damaging	0.74
R9275:Prune2	UTSW	19	17,123,780 (GRCm38)	missense	probably benign	0.06
R9278:Prune2	UTSW	19	17,123,780 (GRCm38)	missense	probably benign	0.06
R9290:Prune2	UTSW	19	17,168,327 (GRCm38)	missense	probably benign	0.41
R9305:Prune2	UTSW	19	17,120,261 (GRCm38)	missense	probably benign	0.14
R9317:Prune2	UTSW	19	17,121,670 (GRCm38)	missense	probably benign	0.00
R9354:Prune2	UTSW	19	17,122,622 (GRCm38)	missense	probably benign	0.43
R9373:Prune2	UTSW	19	17,122,138 (GRCm38)	missense	probably benign
R9394:Prune2	UTSW	19	17,003,689 (GRCm38)	missense	probably damaging	1.00
R9405:Prune2	UTSW	19	17,216,344 (GRCm38)	missense	probably damaging	0.99
R9476:Prune2	UTSW	19	17,119,342 (GRCm38)	missense	possibly damaging	0.64
R9532:Prune2	UTSW	19	17,122,430 (GRCm38)	missense	probably benign	0.00
X0019:Prune2	UTSW	19	17,121,517 (GRCm38)	missense	probably benign	0.16
X0028:Prune2	UTSW	19	17,122,885 (GRCm38)	missense	probably damaging	1.00
X0064:Prune2	UTSW	19	17,122,375 (GRCm38)	missense	probably damaging	1.00
X0066:Prune2	UTSW	19	17,118,790 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGACCATCAGGTACTAGCTGTGGAC -3'
(R):5'- GATTGGCTGCTCAAACCAGCAAC -3'

Sequencing Primer
(F):5'- CAGGTACTAGCTGTGGACTACATC -3'
(R):5'- AGTTCTACCAGGAGACTCAGGC -3'

Posted On

2014-01-05