Incidental Mutation 'R1111:Olfr829'
ID96747
Institutional Source Beutler Lab
Gene Symbol Olfr829
Ensembl Gene ENSMUSG00000051414
Gene Nameolfactory receptor 829
SynonymsGA_x6K02T2PVTD-12599710-12600648, MOR147-1
MMRRC Submission 039184-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.165) question?
Stock #R1111 (G1)
Quality Score225
Status Not validated
Chromosome9
Chromosomal Location18854933-18859080 bp(+) (GRCm38)
Type of Mutationmakesense
DNA Base Change (assembly) A to T at 18857592 bp
ZygosityHeterozygous
Amino Acid Change Stop codon to Cysteine at position 313 (*313C)
Ref Sequence ENSEMBL: ENSMUSP00000148395 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000058411] [ENSMUST00000212229]
Predicted Effect probably null
Transcript: ENSMUST00000058411
AA Change: *322C
SMART Domains Protein: ENSMUSP00000058101
Gene: ENSMUSG00000051414
AA Change: *322C

DomainStartEndE-ValueType
Pfam:7tm_4 40 317 2e-52 PFAM
Pfam:7TM_GPCR_Srsx 44 174 1e-10 PFAM
Pfam:7tm_1 50 299 1.6e-21 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000212229
AA Change: *313C
Coding Region Coverage
  • 1x: 99.0%
  • 3x: 98.1%
  • 10x: 95.7%
  • 20x: 91.4%
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 11 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adsl T A 15: 80,967,660 N421K probably damaging Het
Crip2 C T 12: 113,144,074 Q86* probably null Het
Fabp3 C T 4: 130,312,387 T57I probably benign Het
Gtf3c3 C T 1: 54,417,778 A488T probably damaging Het
Kcp T C 6: 29,485,423 S1191G probably benign Het
Nr5a2 A T 1: 136,882,421 probably null Het
Rdm1 T C 11: 101,633,895 V218A probably benign Het
Slc22a4 T C 11: 54,007,841 T142A probably benign Het
Tgfbrap1 G A 1: 43,051,976 A663V probably benign Het
Togaram1 A G 12: 65,006,341 N1282D probably damaging Het
Zfp687 T C 3: 95,009,512 S768G probably damaging Het
Other mutations in Olfr829
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01142:Olfr829 APN 9 18857534 missense probably damaging 0.97
IGL01696:Olfr829 APN 9 18857056 missense probably benign 0.19
IGL02285:Olfr829 APN 9 18856990 missense possibly damaging 0.87
R0133:Olfr829 UTSW 9 18856629 start codon destroyed probably null
R0173:Olfr829 UTSW 9 18857029 missense probably damaging 0.98
R0270:Olfr829 UTSW 9 18856831 missense probably damaging 1.00
R0449:Olfr829 UTSW 9 18856649 missense probably benign 0.00
R1462:Olfr829 UTSW 9 18857111 missense probably benign 0.30
R1462:Olfr829 UTSW 9 18857111 missense probably benign 0.30
R1845:Olfr829 UTSW 9 18857486 missense possibly damaging 0.95
R4090:Olfr829 UTSW 9 18857102 missense probably benign 0.00
R4096:Olfr829 UTSW 9 18856637 missense probably benign
R4097:Olfr829 UTSW 9 18856637 missense probably benign
R4755:Olfr829 UTSW 9 18857180 missense probably benign 0.03
R4867:Olfr829 UTSW 9 18857566 missense probably benign 0.00
R5084:Olfr829 UTSW 9 18857336 missense probably benign 0.43
R7216:Olfr829 UTSW 9 18857336 missense probably benign 0.43
R7252:Olfr829 UTSW 9 18857252 missense probably damaging 1.00
R7300:Olfr829 UTSW 9 18857234 missense not run
R7412:Olfr829 UTSW 9 18856789 missense possibly damaging 0.51
R8079:Olfr829 UTSW 9 18857429 missense possibly damaging 0.54
X0024:Olfr829 UTSW 9 18857024 missense probably damaging 1.00
X0057:Olfr829 UTSW 9 18856637 missense probably benign
Predicted Primers
Posted On2014-01-05