Incidental Mutation 'R0904:1700011L22Rik'
ID 99134
Institutional Source Beutler Lab
Gene Symbol 1700011L22Rik
Ensembl Gene ENSMUSG00000031682
Gene Name RIKEN cDNA 1700011L22 gene
Synonyms
MMRRC Submission 039062-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.050) question?
Stock # R0904 (G1)
Quality Score 225
Status Validated
Chromosome 8
Chromosomal Location 79210431-79248570 bp(-) (GRCm38)
Type of Mutation start gained
DNA Base Change (assembly) A to G at 79248489 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000034109 (fasta)
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000034109
Predicted Effect noncoding transcript
Transcript: ENSMUST00000210889
Meta Mutation Damage Score 0.0898 question?
Coding Region Coverage
  • 1x: 99.4%
  • 3x: 98.8%
  • 10x: 97.2%
  • 20x: 94.7%
Validation Efficiency 89% (34/38)
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2810474O19Rik G A 6: 149,328,269 A938T probably damaging Het
9230110F15Rik T C 9: 35,839,070 D102G probably damaging Het
Abca13 T C 11: 9,298,740 V2829A probably benign Het
Adk G T 14: 21,092,428 D26Y probably damaging Het
Bpifb9a T C 2: 154,264,225 probably benign Het
Dap G A 15: 31,272,380 probably benign Het
Eqtn A T 4: 94,907,655 S270T probably benign Het
Fam193a A G 5: 34,462,143 D764G probably damaging Het
Fbxl6 A T 15: 76,537,083 probably null Het
Gm13212 T C 4: 145,622,175 Y61H possibly damaging Het
Gm3259 A C 5: 95,341,327 T210P probably damaging Het
Gtf3c1 A T 7: 125,668,842 probably benign Het
H2-D1 G C 17: 35,263,861 M122I probably benign Het
Lgr6 C T 1: 134,994,010 A199T probably damaging Het
Map1s C A 8: 70,914,188 P579Q probably damaging Het
Mapk10 A G 5: 102,987,280 probably benign Het
Mllt6 C G 11: 97,664,998 C51W probably damaging Het
Mzf1 C A 7: 13,052,771 R124L possibly damaging Het
Naip2 T C 13: 100,161,854 E558G probably benign Het
Naip2 C T 13: 100,161,860 G556D probably benign Het
Neurod2 G T 11: 98,327,321 T339K probably benign Het
Nfya G A 17: 48,395,787 Q29* probably null Het
Nipbl A T 15: 8,361,718 D257E probably benign Het
Pex5 G A 6: 124,399,937 probably benign Het
Prx T A 7: 27,518,294 F879Y probably damaging Het
Scai G A 2: 39,075,152 T560M possibly damaging Het
Slfn10-ps T C 11: 83,035,409 noncoding transcript Het
Spdye4b A G 5: 143,195,668 probably benign Het
Ss18l1 A G 2: 180,059,354 Y287C probably damaging Het
Tpbg C A 9: 85,844,564 F195L unknown Het
Trbv16 T C 6: 41,151,847 probably benign Het
Unc5c A G 3: 141,803,840 T620A probably benign Het
Vangl1 A G 3: 102,183,994 S259P probably damaging Het
Vmn1r52 T A 6: 90,179,464 M71K probably damaging Het
Vmn2r23 A T 6: 123,742,135 I816F probably damaging Het
Other mutations in 1700011L22Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02969:1700011L22Rik APN 8 79220237 splice site probably benign
IGL03344:1700011L22Rik APN 8 79248376 missense probably damaging 1.00
IGL02835:1700011L22Rik UTSW 8 79210655 nonsense probably null
R0331:1700011L22Rik UTSW 8 79229392 missense probably benign 0.08
R3801:1700011L22Rik UTSW 8 79248293 missense probably benign 0.06
R3804:1700011L22Rik UTSW 8 79248293 missense probably benign 0.06
R4606:1700011L22Rik UTSW 8 79210745 missense probably benign 0.00
R6045:1700011L22Rik UTSW 8 79229367 missense probably benign 0.00
R6993:1700011L22Rik UTSW 8 79248424 missense possibly damaging 0.91
R7249:1700011L22Rik UTSW 8 79248341 missense probably benign 0.00
R7442:1700011L22Rik UTSW 8 79220290 missense probably damaging 0.99
R8798:1700011L22Rik UTSW 8 79210751 nonsense probably null
Z1177:1700011L22Rik UTSW 8 79248296 missense probably damaging 1.00
Predicted Primers
Posted On 2014-01-10